LOCUS       NM_001004157            2884 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus scavenger receptor class F, member 1 (Scarf1), mRNA.
ACCESSION   NM_001004157 XM_354628
VERSION     NM_001004157.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2884)
  AUTHORS   Jorge,A.M., Lao,T., Kim,R., Licciardi,S., El Khoury,J.,
            Luster,A.D., Means,T.K. and Ramirez-Ortiz,Z.G.
  TITLE     SCARF1-Induced Efferocytosis Plays an Immunomodulatory Role in
            Humans, and Autoantibodies Targeting SCARF1 Are Produced in
            Patients with Systemic Lupus Erythematosus
  JOURNAL   J Immunol 208 (4), 955-967 (2022)
   PUBMED   35082161
  REMARK    GeneRIF: SCARF1-Induced Efferocytosis Plays an Immunomodulatory
            Role in Humans, and Autoantibodies Targeting SCARF1 Are Produced in
            Patients with Systemic Lupus Erythematosus.
REFERENCE   2  (bases 1 to 2884)
  AUTHORS   Pisko,J., Spirkova,A., Cikos,S., Olexikova,L., Kovarikova,V.,
            Sefcikova,Z. and Fabian,D.
  TITLE     Apoptotic cells in mouse blastocysts are eliminated by neighbouring
            blastomeres
  JOURNAL   Sci Rep 11 (1), 9228 (2021)
   PUBMED   33927296
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2884)
  AUTHORS   Murshid,A., Gong,J., Prince,T., Borges,T.J. and Calderwood,S.K.
  TITLE     Scavenger receptor SREC-I mediated entry of TLR4 into lipid
            microdomains and triggered inflammatory cytokine release in RAW
            264.7 cells upon LPS activation
  JOURNAL   PLoS One 10 (4), e0122529 (2015)
   PUBMED   25836976
  REMARK    GeneRIF: SREC-I became associated with TLR4 on binding bacterial
            lipopolysaccharides in RAW 264.7.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2884)
  AUTHORS   Ramirez-Ortiz,Z.G., Pendergraft,W.F. 3rd, Prasad,A., Byrne,M.H.,
            Iram,T., Blanchette,C.J., Luster,A.D., Hacohen,N., El Khoury,J. and
            Means,T.K.
  TITLE     The scavenger receptor SCARF1 mediates the clearance of apoptotic
            cells and prevents autoimmunity
  JOURNAL   Nat Immunol 14 (9), 917-926 (2013)
   PUBMED   23892722
  REMARK    GeneRIF: The scavenger receptor SCARF1 mediates the clearance of
            apoptotic cells and prevents autoimmunity.
REFERENCE   5  (bases 1 to 2884)
  AUTHORS   Murshid,A., Gong,J. and Calderwood,S.K.
  TITLE     Heat shock protein 90 mediates efficient antigen cross presentation
            through the scavenger receptor expressed by endothelial cells-I
  JOURNAL   J Immunol 185 (5), 2903-2917 (2010)
   PUBMED   20686127
  REMARK    GeneRIF: SREC-I mediated internalization of Hsp90-ovalbumin
            polypeptide complexes through an endocytic pathway known as the
            glycosylphosphatidylinositol-anchored protein-enriched early
            endosomal compartment to recycling endosomes.
REFERENCE   6  (bases 1 to 2884)
  AUTHORS   Hasegawa,H., Abbott,S., Han,B.X., Qi,Y. and Wang,F.
  TITLE     Analyzing somatosensory axon projections with the sensory
            neuron-specific Advillin gene
  JOURNAL   J Neurosci 27 (52), 14404-14414 (2007)
   PUBMED   18160648
REFERENCE   7  (bases 1 to 2884)
  AUTHORS   Ishii,J., Adachi,H., Shibata,N., Arai,H. and Tsujimoto,M.
  TITLE     Scavenger receptor expressed by endothelial cells (SREC)-I
            interacts with protein phosphatase 1alpha in L cells to induce
            neurite-like outgrowth
  JOURNAL   Biochem Biophys Res Commun 360 (1), 269-274 (2007)
   PUBMED   17586471
  REMARK    GeneRIF: Our system may be useful for the elucidation of the
            mechanism of morphological maturation of neuronal cells such as
            dorsal root ganglion neurons that express SREC-I during early
            development.
REFERENCE   8  (bases 1 to 2884)
  AUTHORS   Shibata,M., Ishii,J., Koizumi,H., Shibata,N., Dohmae,N., Takio,K.,
            Adachi,H., Tsujimoto,M. and Arai,H.
  TITLE     Type F scavenger receptor SREC-I interacts with advillin, a member
            of the gelsolin/villin family, and induces neurite-like outgrowth
  JOURNAL   J Biol Chem 279 (38), 40084-40090 (2004)
   PUBMED   15247299
  REMARK    GeneRIF: interaction of SREC-I and advillin are involved in the
            development of dorsal root ganglion neurons by inducing the
            described morphological changes.
REFERENCE   9  (bases 1 to 2884)
  AUTHORS   Tamura,Y., Osuga,J., Adachi,H., Tozawa,R., Takanezawa,Y.,
            Ohashi,K., Yahagi,N., Sekiya,M., Okazaki,H., Tomita,S., Iizuka,Y.,
            Koizumi,H., Inaba,T., Yagyu,H., Kamada,N., Suzuki,H., Shimano,H.,
            Kadowaki,T., Tsujimoto,M., Arai,H., Yamada,N. and Ishibashi,S.
  TITLE     Scavenger receptor expressed by endothelial cells I (SREC-I)
            mediates the uptake of acetylated low density lipoproteins by
            macrophages stimulated with lipopolysaccharide
  JOURNAL   J Biol Chem 279 (30), 30938-30944 (2004)
   PUBMED   15145948
REFERENCE   10 (bases 1 to 2884)
  AUTHORS   Ishii,J., Adachi,H., Aoki,J., Koizumi,H., Tomita,S., Suzuki,T.,
            Tsujimoto,M., Inoue,K. and Arai,H.
  TITLE     SREC-II, a new member of the scavenger receptor type F family,
            trans-interacts with SREC-I through its extracellular domain
  JOURNAL   J Biol Chem 277 (42), 39696-39702 (2002)
   PUBMED   12154095
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC080288.1, AK220215.1 and AK133477.1.
            
            On Feb 14, 2006 this sequence version replaced NM_001004157.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133477.1, AK220215.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                BC080288.1         1-16
            17-2518             AK220215.1         1-2502
            2519-2884           AK133477.1         2502-2867
FEATURES             Location/Qualifiers
     source          1..2884
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.92 cM"
     gene            1..2884
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /note="scavenger receptor class F, member 1"
                     /db_xref="GeneID:380713"
                     /db_xref="MGI:MGI:2449455"
     exon            1..150
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            151..209
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            210..311
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            312..834
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            835..1053
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1182
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1286
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1404
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1526
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1527..1673
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..2884
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2846..2851
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /note="hexamer: GATAAA"
     regulatory      2857..2862
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /note="hexamer: ATTAAA"
     regulatory      2861..2866
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /note="hexamer: AACAAA"
     polyA_site      2866
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /note="major polyA site"
     polyA_site      2877
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /note="major polyA site"
     polyA_site      2882
                     /gene="Scarf1"
                     /gene_synonym="mKIAA0149; SREC; SREC-I"
                     /note="major polyA site"
ORIGIN      
        1 gagctgtggg gaccagatca aaccaggccc tcctaccatg ctggccgcca tgggactaga
       61 gctggtgttc tcactgttgc tgctctggac tcaggggacc cagggatcca cgctagaccc
      121 tgctggtcag cacgtctgta aaggcagcag cccctctgag ctccagtgtt gtcccggctg
      181 gaggcagaaa gatcaagaat gcaccatccc catctgtgag gggcctgatg cctgcaggaa
      241 agaagaggtg tgcgtgaagc cgggcctctg tcggtgtaaa cctggattct tcggagccca
      301 gtgcagctcc cgctgtccag gacagtactg gggccacgac tgtcgtgaga cctgcccctg
      361 tcatccacgt ggccagtgcg aaccggccac gggtgattgc caatgccagc ctaactactg
      421 gggcaggctc tgtgagttcc cctgcacctg cggcccccac ggacagtgcg acccaaagac
      481 aggcttgtgc cactgtgacc ctggctggtg gtcacccacg tgtcgtcgcc catgccagtg
      541 caacccagcc tcacgctgtg accaggccac tggaacctgt gtatgcccgc cgggctggtg
      601 gggccgccgc tgcagcttca gttgcaactg ccacacctcg ccctgcatgc aggactccgg
      661 ccgctgcgtc tgcctgccgg gctggtgggg tccggagtgc agtcgtaagt gccagtgtgt
      721 gcgaggccaa tgcagcgtta cttctggcca ctgttcctgc cctcctggct tccatggaat
      781 ccgctgtgag ctgccttgca accctggcca ctatggggca cagtgcaaag aaagctgtgg
      841 ccactgtgag ctgaatgcca catgctctcc agtcaccggc aactgtgagt cctgcaagcc
      901 aggctggaac ggtactcagt gcaagcagcc atgtcctgca ggcacctttg gtgagaggtg
      961 cactgggcag tgcccccgct gccggcttgg ggagccctgt caagcggaaa ctgggcactg
     1021 ccagcactgc gaccccggtt ggctggggca caggtgtgag aacccttgtc cccttggcac
     1081 ctttgggaag ggctgcagct caacctgccc tgcctgtgct caggggactt gcgatgccgt
     1141 gactggggaa tgtgtctgca gtgctggcta ctgggggacc agctgcaaca gttcctgccc
     1201 agctggcttc cacggaaaca actgctctat gccctgccaa tgcccagagg ggctctgcca
     1261 ccctgtgtct gggacctgcc agctgggccg tcatggtaag aacgccctca ttgtgggcat
     1321 cctggtacct ctgctgctgc tcctcatggg catcgtctgc tgtgcctact gctgctcagg
     1381 aacccgactg gaccccaagg acaggcctga gagaaatggg gctgcctttt tcagaatgaa
     1441 gcagcaggta tggggggccc tcaccaactt gggctcggca ctgccctgtg gctccctcag
     1501 taactacaag ctaccctggg tgacagtttc tcatcacgat ccagaggtcc ccttcaacca
     1561 tagcttcatc gagcccccct ctgccggctg ggcctctgac gactccttct cttctgatcc
     1621 tgactctgga gaagaggacg aagctcatgc ctacttcgtg ccgcctcgag aagagatggt
     1681 ccctatggcc caagaagagt caccagaagc cagccttcct ggaggctcct tccctccccc
     1741 tgaggatgcc tccacaccat tccccattcc acgtacctcc agcctggcta gggccaagag
     1801 gccatccgtc tcctttgctg aaggcacgaa gtttgcacca cagaatggcc gaagctctgg
     1861 ggatctctcc agccccatac gaaaacccaa gagactctcc agaggtgctc aaccccgtcc
     1921 tgaagggcag gaggcggagg agtctacagg cccagagcaa gtgaacacag aggaggatgc
     1981 tcctacggcc acaagctctg gagatcctgc cactagtcac ggccaacttc cacctggtag
     2041 ccagatggta gctgagtgtg cggagaccac tgatggaggc atccaggaga gctcaggatc
     2101 tgtggccact atctatatgc tggcagggac acctcagaaa cctgagggtc ctgtctggtc
     2161 tgtctttcgt cgtttgggaa actaccagaa agatcagatg gatcccaaag taaagagtgc
     2221 tatccctaag cctctgcgcc gatctctggg tcggaaccag gccagcgctg gctcagctcc
     2281 aggtgctgtg ctctcccagg ccatggagtc caccgcagtt agaccagagg aaacacccag
     2341 aggtctggga gatggcattg agagctcagg gactgtccag gagccagacg ctggaggcag
     2401 ttccctggaa caggattccc agaagcaggc ggaagagaag gagcaagagg agcccctgta
     2461 tgagaatgtt gtgcccatgt ccgtgccgcc acagcactga ggaccttggt gagttcccgg
     2521 gaagcctgtg gatggggatg cagggagagc gggatgctga agctgctgtg gaccagattg
     2581 ggctttgtgc ctgaaaatga tgccatagct gtgacagact aaacagaaac tctgccgtga
     2641 aagaggcaag ggttagaggc cagctggttg tgggtctggc cctaggtggg attggaaggc
     2701 ctgagcggag accaaggtca gaggaaggag gagacggcga cagggctttt cctccattgt
     2761 tctgaattct gtcctgagac tattcttttc catctcttca aaacattttt tttttctgaa
     2821 ctggaaaaca acctaaatgt ttgatgataa agattgatta aacaaatatt tcttttagaa
     2881 aatt
//
