LOCUS       NM_172604               3405 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus scavenger receptor class A, member 3 (Scara3), mRNA.
ACCESSION   NM_172604
VERSION     NM_172604.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3405)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3405)
  AUTHORS   Chen,P., Hu,B., Xie,L.Q., Jiang,T.J., Xia,Z.Y. and Peng,H.
  TITLE     Scara3 regulates bone marrow mesenchymal stem cell fate switch
            between osteoblasts and adipocytes by promoting Foxo1
  JOURNAL   Cell Prolif 54 (8), e13095 (2021)
   PUBMED   34254370
  REMARK    GeneRIF: Scara3 regulates bone marrow mesenchymal stem cell fate
            switch between osteoblasts and adipocytes by promoting Foxo1.
REFERENCE   3  (bases 1 to 3405)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3405)
  AUTHORS   Wu,Y., Wei,F.Y., Kawarada,L., Suzuki,T., Araki,K., Komohara,Y.,
            Fujimura,A., Kaitsuka,T., Takeya,M., Oike,Y., Suzuki,T. and
            Tomizawa,K.
  TITLE     Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is
            Required for Mitochondrial Translation and Is Involved in
            Reversible Infantile Liver Injury
  JOURNAL   PLoS Genet 12 (9), e1006355 (2016)
   PUBMED   27689697
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3405)
  AUTHORS   Cameron,T.L., Gresshoff,I.L., Bell,K.M., Pirog,K.A., Sampurno,L.,
            Hartley,C.L., Sanford,E.M., Wilson,R., Ermann,J.,
            Boot-Handford,R.P., Glimcher,L.H., Briggs,M.D. and Bateman,J.F.
  TITLE     Cartilage-specific ablation of XBP1 signaling in mouse results in a
            chondrodysplasia characterized by reduced chondrocyte proliferation
            and delayed cartilage maturation and mineralization
  JOURNAL   Osteoarthritis Cartilage 23 (4), 661-670 (2015)
   PUBMED   25600960
REFERENCE   6  (bases 1 to 3405)
  AUTHORS   Prabhudas,M., Bowdish,D., Drickamer,K., Febbraio,M., Herz,J.,
            Kobzik,L., Krieger,M., Loike,J., Means,T.K., Moestrup,S.K.,
            Post,S., Sawamura,T., Silverstein,S., Wang,X.Y. and El Khoury,J.
  TITLE     Standardizing scavenger receptor nomenclature
  JOURNAL   J Immunol 192 (5), 1997-2006 (2014)
   PUBMED   24563502
  REMARK    Review article
REFERENCE   7  (bases 1 to 3405)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   8  (bases 1 to 3405)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
REFERENCE   9  (bases 1 to 3405)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   10 (bases 1 to 3405)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC126444.3 and
            AC125058.4.
            
            On May 2, 2007 this sequence version replaced NM_172604.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK048423.1, BC051636.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-249               AC126444.3         52930-53178         c
            250-348             AC126444.3         37645-37743         c
            349-468             AC126444.3         35797-35916         c
            469-567             AC126444.3         32538-32636         c
            568-1611            AC126444.3         30232-31275         c
            1612-3405           AC125058.4         6383-8176
FEATURES             Location/Qualifiers
     source          1..3405
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 34.36 cM"
     gene            1..3405
                     /gene="Scara3"
                     /gene_synonym="APC7; C130058N24Rik; CSR; CSR1; MSLR1;
                     MSRL1"
                     /note="scavenger receptor class A, member 3"
                     /db_xref="GeneID:219151"
                     /db_xref="MGI:MGI:2444418"
     exon            1..249
                     /gene="Scara3"
                     /gene_synonym="APC7; C130058N24Rik; CSR; CSR1; MSLR1;
                     MSRL1"
                     /inference="alignment:Splign:2.1.0"
     CDS             243..2063
                     /gene="Scara3"
                     /gene_synonym="APC7; C130058N24Rik; CSR; CSR1; MSLR1;
                     MSRL1"
                     /codon_start=1
                     /product="scavenger receptor class A member 3"
                     /protein_id="NP_766192.1"
                     /db_xref="CCDS:CCDS49524.1"
                     /db_xref="GeneID:219151"
                     /db_xref="MGI:MGI:2444418"
                     /translation="MKVRSAGSDRDVLCVTEEDLAGEDEDMPSFPCTQEGRAGPRCNR
                     CQKNLSLHTSVRILYLFLTLLLVAVAVLASLVFRKVDSLSEDISLAQSIYNKKLVSMQ
                     ENLQGLDPKALINCSFCREAEQLGQEIRKVQEELEGLQKMLLAQEVQLDQTSQTHELL
                     STRSSQISQEMGSCSFSIHQVNQSLGLFLAQVRGWQATTAGMDITLKDLTQECYDVKA
                     AVHQINFTVGQTAEWIHGIQRKTDEETLTLQKIVTDWQNYTRLFGGLRTTSAKTGEIV
                     KTIQTTLGASSQRISQNSESMHDLVLQVMGLQLQLDNISSFLDDHEENMHDLQYHTRY
                     AQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSMLKYLDDVRLSCTLGFHTH
                     AEELYYLNKSVSLMLGTTDLLRERFSLLSARLDFNVRNLSMIMEEMKAVDTHHGEILR
                     NVTVIRGVPGPPGPRGLKGDTGVKGPVGSRGPKGDPGNLGPPGPQGPQGQPGEPGPVG
                     ERGPAGPRGFPGLKGSKGSFGTGGPRGQPGPKGDVGPLGPEGPPGSPGPSGPQGKPGI
                     SGKTGSPGQRGATGPKGEPGIQGPPGLPGPPGPPGNQSPY"
     exon            250..348
                     /gene="Scara3"
                     /gene_synonym="APC7; C130058N24Rik; CSR; CSR1; MSLR1;
                     MSRL1"
                     /inference="alignment:Splign:2.1.0"
     exon            349..468
                     /gene="Scara3"
                     /gene_synonym="APC7; C130058N24Rik; CSR; CSR1; MSLR1;
                     MSRL1"
                     /inference="alignment:Splign:2.1.0"
     exon            469..567
                     /gene="Scara3"
                     /gene_synonym="APC7; C130058N24Rik; CSR; CSR1; MSLR1;
                     MSRL1"
                     /inference="alignment:Splign:2.1.0"
     exon            568..1611
                     /gene="Scara3"
                     /gene_synonym="APC7; C130058N24Rik; CSR; CSR1; MSLR1;
                     MSRL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..3405
                     /gene="Scara3"
                     /gene_synonym="APC7; C130058N24Rik; CSR; CSR1; MSLR1;
                     MSRL1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacacagctc gccgggctcc ggcgggcagc gtggtgtccc cagcctgcga cccccgggat
       61 ccttctcctg cttcgccgcc cgagcagcgg cacagcgccg catgtgtccc cacccaagcc
      121 tcagacccgc gggccgcact taggggccgc ggtcggtgcc tggggaggac cccggcttcc
      181 cgctccatcc aaggctactc gagcgccgcg ggggccctgc agaggcccgc gcagaaggga
      241 ccatgaaagt gagatcagct ggcagtgaca gggatgtact gtgtgtcact gaagaggacc
      301 tggctggtga agacgaggac atgccatcct tcccatgcac ccaagagggc cgggcaggac
      361 cccgctgcaa ccgctgccag aagaacctat ctttgcacac atcagtgcgg attttgtacc
      421 tcttcctcac tctgctcctg gtggccgtgg ctgtgctggc ctctctggtt tttagaaagg
      481 tggactctct ctcagaagat atctccttgg cccagtccat ctataataag aagcttgtgt
      541 caatgcaaga aaatcttcaa ggactagacc caaaagccct gatcaattgt tccttttgcc
      601 gtgaggctga gcagctgggg caagagatca ggaaggtcca ggaggagctg gaggggcttc
      661 agaagatgct gctagcccag gaggtccagc tggaccagac ctcccagacc catgagctgc
      721 tctccaccag aagcagtcaa atctcccagg agatgggcag ttgctccttc tccattcacc
      781 aggtcaatca gtccctggga ctcttcctgg cacaggtgag gggctggcag gccaccacag
      841 caggcatgga catcaccctg aaggacctca cccaggagtg ctatgatgtc aaggctgctg
      901 tacaccagat caacttcacg gtgggccaga ctgctgagtg gatccacggg atccaaagga
      961 agacagatga ggagaccctg accctgcaga agatagtcac tgactggcag aactacacca
     1021 gactctttgg gggtctgcga accacctctg ccaagactgg cgaaatagtc aagaccattc
     1081 agaccaccct gggggcctcc tcacagcgca ttagccagaa ttctgagagc atgcatgact
     1141 tggttctgca ggtcatgggc ctacagctac agctggacaa catctcttcc tttttggatg
     1201 accatgagga gaacatgcat gacctccaat accacacccg atatgcccag aatcgcacag
     1261 tggaaaggtt cgagtctctg gaaggacgta tggcttctca tgagattgaa atcggcacta
     1321 tcttcaccaa tatcaatgcc accgacaacc acgtgcacag catgctcaag tacctggacg
     1381 acgtgcggct gtcttgcaca ctgggcttcc acacccatgc tgaagagctc tactacctga
     1441 ataaatccgt ctccctcatg ctgggcacca cagatctgct cagggagcgc ttcagtctgc
     1501 tcagtgcccg gttagacttc aatgtccgaa acctctccat gatcatggag gaaatgaagg
     1561 ctgtggacac acaccacgga gaaatccttc gcaatgtcac cgtcatccga ggtgtccccg
     1621 gccctccagg accaagagga ctcaaaggag atacaggcgt gaaaggacct gttggtagca
     1681 gaggacctaa aggggatcct ggcaatctgg gacccccagg acctcagggt cctcaggggc
     1741 agcctgggga gccaggacct gtgggagaaa gagggccagc tggccccaga ggctttccag
     1801 gcctcaaagg ctcaaagggc agctttggca ctggaggacc aagggggcag ccaggcccca
     1861 agggggatgt ggggccccta gggccagagg ggcccccagg gtctccagga ccttcagggc
     1921 ctcagggaaa gccaggaatt tcaggaaaga cagggtcacc aggccagcga ggggccacag
     1981 ggcctaaggg tgaaccaggc atccagggtc cccctggact acctggacct ccaggtccac
     2041 cagggaacca gagcccctac tgaaaaaagt ctttggcctg atgctgccat gcaggttgga
     2101 gaggtgaggg tcagagaaag cagccagaag ggttgctaca atcattgttc tttgatccta
     2161 atacgagggt gtctcttaga gctgactgca tagccttaag cttcccaata atgactgtac
     2221 cataggaaaa cagctcacct ccccctactt ttttctgctg actaaagggg agtctattgg
     2281 gtttctatgg ctggttagaa ggaaaggctg tgagagcctg ctggtggggg aagggatagc
     2341 tacctgggga agaatgtctt agatctcttg gatggtaact actctggtct ctgcaatgac
     2401 ttaacaccca tgcgagccaa gtcttgaaga aaaaaaaaat ccagggaaac ttttggggca
     2461 ttataaatga aactccaggg atagcagcct cccctctttc cccctccctc gacacataac
     2521 agtcacggta gaatcatgtg gagctgcctt gatccacaca gggcaagaga agtctgcctg
     2581 gctggcattc ccaggcctta tgcatggata ctgaccctga caagttcaga gagtttttat
     2641 tcacatgtcc agaaaattcc tcttttcagt cttacctctg catctcaaga gtggcctgga
     2701 agaaacccaa gcagagtttc atcggcaggt caagaaccta caggtcccag agcactctgc
     2761 ttgacttcta tccagctccc aggaagacca cagggctgga ggtgggagga catatcaggg
     2821 gaaaactccc ctctccaaag ccaccacttg ttcaacctac tctgccttgt cttactccca
     2881 gtaatagcca aggaggaaga agctggtaac acggcagctc ttgcctcctc ctcttggttg
     2941 acctgagaca gatgcacaat gacctcaccc cacaatgacc taagatggct ggagttcttt
     3001 cccacatgaa cagcaagctg gaccaggcat gcgaaaggct gaacgtgcac aaggaacctt
     3061 agatgttact tctcgtcttt catgaacttc ttgaatacac tggcagaaag ggatgctggg
     3121 aaaggcctgc atttccttga ctcattttgt agagctgccc tgatccttca tactccagca
     3181 gactcaaaca ctcctgggca gaggctagag ctgtgtcctc tcttgccctg cctcagagac
     3241 ctgtcttctt cttcctgttc aaaggctctg tgctaccttc ttcatcaata tcagtgtgca
     3301 actggcttgc acgacccatc tacccctgct gtataattgt cctgtctaca tatgaaaata
     3361 tcatgcaaca caatatcgct gacccagtaa agagctgttt ccagt
//
