LOCUS       NM_001357652            5249 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus S phase cyclin A-associated protein in the ER
            (Scaper), transcript variant 2, mRNA.
ACCESSION   NM_001357652 XM_006511166
VERSION     NM_001357652.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5249)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5249)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5249)
  AUTHORS   Tatour,Y., Bar-Joseph,H., Shalgi,R. and Ben-Yosef,T.
  TITLE     Male sterility and reduced female fertility in SCAPER-deficient
            mice
  JOURNAL   Hum Mol Genet 29 (13), 2240-2249 (2020)
   PUBMED   32510560
  REMARK    GeneRIF: Male sterility and reduced female fertility in
            SCAPER-deficient mice.
REFERENCE   4  (bases 1 to 5249)
  AUTHORS   Tatour,Y., Sanchez-Navarro,I., Chervinsky,E., Hakonarson,H.,
            Gawi,H., Tahsin-Swafiri,S., Leibu,R., Lopez-Molina,M.I.,
            Fernandez-Sanz,G., Ayuso,C. and Ben-Yosef,T.
  TITLE     Mutations in SCAPER cause autosomal recessive retinitis pigmentosa
            with intellectual disability
  JOURNAL   J Med Genet 54 (10), 698-704 (2017)
   PUBMED   28794130
REFERENCE   5  (bases 1 to 5249)
  AUTHORS   Sasaki,N., Kurisu,J. and Kengaku,M.
  TITLE     Sonic hedgehog signaling regulates actin cytoskeleton via
            Tiam1-Rac1 cascade during spine formation
  JOURNAL   Mol Cell Neurosci 45 (4), 335-344 (2010)
   PUBMED   20654717
REFERENCE   6  (bases 1 to 5249)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   7  (bases 1 to 5249)
  AUTHORS   Mulligan,M.K., Ponomarev,I., Hitzemann,R.J., Belknap,J.K.,
            Tabakoff,B., Harris,R.A., Crabbe,J.C., Blednov,Y.A., Grahame,N.J.,
            Phillips,T.J., Finn,D.A., Hoffman,P.L., Iyer,V.R., Koob,G.F. and
            Bergeson,S.E.
  TITLE     Toward understanding the genetics of alcohol drinking through
            transcriptome meta-analysis
  JOURNAL   Proc Natl Acad Sci U S A 103 (16), 6368-6373 (2006)
   PUBMED   16618939
REFERENCE   8  (bases 1 to 5249)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
REFERENCE   9  (bases 1 to 5249)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   10 (bases 1 to 5249)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC107819.8, AC159901.2, AC164972.2, CT025567.10 and AC116699.9.
            
            On Nov 4, 2017 this sequence version replaced XM_006511166.3.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice junction compared to variant 1. The resulting isoform (2)
            has the same N- and C-termini but is shorter compared to isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC172119.1, SRR1660813.143010.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AC107819.8         90865-90914
            51-123              AC159901.2         189953-190025       c
            124-187             AC159901.2         188211-188274       c
            188-305             AC159901.2         184674-184791       c
            306-376             AC159901.2         183587-183657       c
            377-571             AC159901.2         180727-180921       c
            572-672             AC159901.2         163969-164069       c
            673-789             AC159901.2         160859-160975       c
            790-947             AC159901.2         152534-152691       c
            948-1207            AC159901.2         143332-143591       c
            1208-1408           AC159901.2         133091-133291       c
            1409-1579           AC159901.2         128435-128605       c
            1580-1655           AC159901.2         127686-127761       c
            1656-1730           AC159901.2         127138-127212       c
            1731-1773           AC164972.2         237280-237322       c
            1774-1885           AC164972.2         236953-237064       c
            1886-2026           AC164972.2         216992-217132       c
            2027-2182           AC164972.2         195526-195681       c
            2183-2325           AC164972.2         194233-194375       c
            2326-2407           AC164972.2         187974-188055       c
            2408-2560           AC164972.2         186478-186630       c
            2561-2668           AC164972.2         185885-185992       c
            2669-2805           AC164972.2         141100-141236       c
            2806-2871           AC164972.2         136865-136930       c
            2872-2998           CT025567.10        235872-235998       c
            2999-3114           CT025567.10        178209-178324       c
            3115-3238           CT025567.10        148234-148357       c
            3239-3471           CT025567.10        102171-102403       c
            3472-3627           CT025567.10        95095-95250         c
            3628-3862           CT025567.10        78548-78782         c
            3863-4012           CT025567.10        72536-72685         c
            4013-4204           AC116699.9         192484-192675       c
            4205-4256           AC116699.9         189870-189921       c
            4257-5249           AC116699.9         186278-187270       c
FEATURES             Location/Qualifiers
     source          1..5249
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 30.13 cM"
     gene            1..5249
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /note="S phase cyclin A-associated protein in the ER"
                     /db_xref="GeneID:244891"
                     /db_xref="MGI:MGI:1925976"
     exon            1..50
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            51..123
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            124..187
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     CDS             182..4360
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /note="isoform 2 is encoded by transcript variant 2; zinc
                     finger protein 291"
                     /codon_start=1
                     /product="S phase cyclin A-associated protein in the
                     endoplasmic reticulum isoform 2"
                     /protein_id="NP_001344581.1"
                     /db_xref="CCDS:CCDS90576.1"
                     /db_xref="GeneID:244891"
                     /db_xref="MGI:MGI:1925976"
                     /translation="MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKP
                     KCQTGGKSKRTIQGTHKTTKQNTAVECKITSTTGEKHFDKSPTKTRHPRKIDLRARYW
                     AFLFDNLRRAVDEIYVTCESDQSVVECKEVLMMLDYYVRDFKALIDWIQLQEKLEKTD
                     AQSRPTSLAWEVKKMSPGRHVIQSPSTDRMNVTSTARRSLNFGSLPGAVTAPCLAPTG
                     VSWADKVKAHHTGSAPPEATPAQSCAPMTVQKTSRKNERKDAEGWETVQRGRPVRSRS
                     TAVIPKVSLVTETLRSKDDSDKENICLLPEESIQKGKLEDRCSTVESLSKDSLLHSSD
                     HPLSERTQFTVCILDDVKNSGSSQDSSVHTSEIPAIDSDAVCVAPQNTTALPTDRVPA
                     ETTGMVTEMTDPSDISNSMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAE
                     ENNDINIETDNDSDFSASMGSGSLSFCGVSLDWNDVLADYEARESWRQNTSWGDIVEE
                     EPARLPGHGIHMHEKLSSPSRKRTIAESKKKYEEKHMKAQQLREKLREEKTLKLQKLL
                     EREKDVRKWKEELLDQRRRMMEEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINT
                     LEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEEKQARDEAVQERKRALEAERQARVE
                     ELLMKRKEQEARIEQQRQEKEKAREDAARERARDREERLAALTAAQQEAMEELQKKIQ
                     LKHDESIRRHMEQIEQRKEKAAELSSGRHASTDYAPKLTPYERKKQCSLCNVLIASEV
                     YLFSHIKGKKHQQAVRENSSIQGRELSDEEVEHLSLKKYVVDIVIESAAPPEPVKDGE
                     ERQKNKKKAKKIKARMNIRAKEYENLVETKNSGSESPYKAKLQRLTKDLVKQLQVQDS
                     GSWVNNKASALDRTLGEIARILEKENVPDQISFQVAGGLTALENILQVVTPATNMNTV
                     SRIPPKSLCNAINVYSLACNNCSENCTDVLFSNKITFLMDLLIHQLTVYVPDENNAVL
                     GRNTNKQVFEGLTTGLLRAGAVVFSCLIANRPDGNSRPATPKISTQEMKNKPSQGDAF
                     NSRVQDLISYVVNMGLIDRLHGCFLSVQGPVDENPKMATFLQHAAGFLRGMCMLCFAV
                     TGRSSSIFDNNHQDPTGLTAALQATDLAGVLHMLYCILFHGTISDAGTSPKDSYTQNT
                     IQVAIQSLRFFNSFAILDLSAFQSVVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEV
                     IVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLITACHNN
                     HQNKLILEQEMSCVLLATFIQDFAQTPGHVDNQSSSLKGKFQNPGNYLELANRFPQQA
                     WEEARQFFLKKEKK"
     exon            188..305
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            306..376
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            377..571
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            572..672
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            673..789
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            790..947
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1207
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1408
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1579
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..1655
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            1656..1773
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..1885
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2026
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2182
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2183..2325
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2407
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2408..2560
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2561..2668
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2669..2805
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2806..2871
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2872..2998
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            2999..3114
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            3115..3238
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            3239..3471
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            3472..3627
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            3628..3862
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            3863..4012
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            4013..4204
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            4205..4256
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     exon            4257..5249
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4860..4865
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /note="hexamer: AATAAA"
     polyA_site      4879
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /note="major polyA site"
     regulatory      5226..5231
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
                     /note="hexamer: AATAAA"
     polyA_site      5249
                     /gene="Scaper"
                     /gene_synonym="C430017I08; D530014O03Rik; Zfp291"
ORIGIN      
        1 tttcccgccg ggacgctggg agccgcccca aagtaagcta agcctcccgg atctgtgttt
       61 ctataccacc gtggattttg ggagattgtg accatcttga aagataacct gttctcattt
      121 aaggaattat aacctatggg attatgtggt aaatgatctt gcctcggaag agaattaaag
      181 aatgatggct tccttccagc gctccaatag tcatgacaaa gtgagaagaa ttgttgctga
      241 ggagggtcgt accgcaagaa acttgatagc ttggagtgtt ccactagaaa gcaaagatga
      301 tgatggaaaa ccgaaatgtc aaactggtgg aaaatctaag aggacaattc aaggcactca
      361 taaaaccact aaacagaata ctgcagtaga atgtaaaata acatccacaa ctggagagaa
      421 gcattttgat aaaagtccta caaaaacaag gcacccaaga aaaattgact taagagctcg
      481 ctactgggca tttctttttg acaatcttcg ccgggcagta gatgaaatct atgtgacttg
      541 tgaatcagat cagagtgtgg tggagtgtaa ggaggtgtta atgatgctgg attactatgt
      601 gagagatttc aaagcattga ttgactggat tcaacttcag gaaaagttag agaagacaga
      661 tgctcaaagc agaccaacct cactggcgtg ggaagtaaag aagatgtctc caggacgtca
      721 tgtgattcaa agcccatcaa cagatagaat gaatgtaaca tcaactgcaa gaagaagctt
      781 aaactttggg agtttacctg gtgcagtaac tgccccatgt ctggctccca caggtgtcag
      841 ttgggctgac aaggtaaagg ctcatcatac tggttctgct cctcctgagg ccacacctgc
      901 tcaatcctgt gcaccaatga cagtgcaaaa gacgtcccgg aaaaatgaac ggaaagatgc
      961 tgagggttgg gagactgttc agagaggtcg gccagtgcgt tcccgatcga cagcagttat
     1021 acctaaagtt tcactagtga cagaaacctt aaggtcaaag gatgacagtg ataaggaaaa
     1081 catatgcctt ttacctgaag aaagcataca gaaaggaaaa cttgaagaca gatgttctac
     1141 tgttgaatcg ttatccaaag actcattatt acattcttct gaccatcctc tttctgagag
     1201 aactcagttc acagtgtgta tattggatga tgtcaagaat tctggtagta gtcaagacag
     1261 ttcagtgcat acttctgaaa taccagctat tgacagtgat gcagtatgtg ttgctccaca
     1321 aaacaccaca gctttgccaa cagacagagt tccagcggag acaacaggaa tggtgactga
     1381 gatgacggac ccttcagaca tttcaaattc tatggcagaa gttctcgcta aaaaagaaga
     1441 gctagcagat cgtctagaaa aggccaatga agaagccatc gccagtgcta ttgctgaaga
     1501 agaacaatta accagagaaa ttgaagctga agaaaacaat gacattaaca tcgagactga
     1561 caacgacagt gacttttctg ccagtatggg cagtgggagt ctatctttct gtggtgtgtc
     1621 tctggactgg aatgatgttc tcgcagatta tgaagctcgt gaatcatggc gtcaaaatac
     1681 atcctgggga gatattgtag aagaggagcc tgccagactt ccagggcatg gaattcacat
     1741 gcatgaaaaa ctttcatcac cttctcgtaa aaggacaatc gcagaatcta aaaagaaata
     1801 tgaagaaaaa cacatgaaag ctcaacagtt aagggaaaag ctacgcgaag agaagacact
     1861 aaagcttcaa aagttgttag aaagggagaa agatgtccga aagtggaagg aagaattact
     1921 agatcaacga cgtaggatga tggaagagaa attacttcat gcagaattta aacgagaggt
     1981 acagctacaa gctattgtga agaaagctca agaggaagaa gctaaggtta atgagattgc
     2041 cttcataaat acccttgaag ctcagaataa acgtcacgat gttttatcaa aactgaagga
     2101 atatgagcag aggcttaatg aattgcagga agaacgtcag agaagacaag aagaaaagca
     2161 agctcgtgat gaggctgtgc aggaacgtaa gagagccttg gaggcagaaa ggcaggcccg
     2221 tgtagaggaa ttattgatga agaggaaaga gcaagaagcc cgaattgagc aacagaggca
     2281 agagaaggag aaagctcgtg aagatgcagc ccgggaaaga gcaagagaca gggaagaacg
     2341 gttggcagcg ctcacagcag ctcagcaaga agctatggaa gagctgcaga aaaaaattca
     2401 gctcaagcat gatgaaagca ttcgaaggca catggaacag attgagcaaa ggaaagaaaa
     2461 agctgctgaa ttaagcagtg ggcggcatgc aagcaccgat tacgccccta aactgacccc
     2521 ttatgaaaga aagaagcagt gttctctctg caatgtcctg atcgcttctg aagtatatct
     2581 ctttagccac attaaaggga aaaaacatca gcaggctgtg agagagaata gcagtatcca
     2641 gggccgtgaa ctttctgatg aggaagtgga acatctgtct ttgaagaagt atgttgttga
     2701 cattgtgatt gaaagtgcag ctccaccaga gcctgtaaaa gatggagaag aacggcaaaa
     2761 gaataagaaa aaagctaaaa agataaaagc acggatgaac atcagggcga aagaatatga
     2821 gaatttagtg gaaaccaaaa attctggctc cgagtcacct tataaagcaa agcttcagag
     2881 attaaccaaa gatcttgtaa aacaacttca agtacaagac agtggctctt gggtaaataa
     2941 taaggcttca gctttggatc ggacccttgg tgagattgct agaatattgg agaaagagaa
     3001 tgtgccagat cagatttcgt ttcaagttgc tggtggatta acagcccttg aaaacatcct
     3061 tcaagtagtg actccagcca caaacatgaa cacggtttca cgaattcctc ctaagtctct
     3121 ctgcaatgca atcaatgttt acagcctcgc ctgcaataac tgctcagaaa actgcactga
     3181 tgttctgttt agtaacaaga ttaccttctt aatggacctc ctgatacacc aattgacggt
     3241 ttatgttcca gatgaaaata atgctgttct aggaagaaat acaaataaac aagtttttga
     3301 aggcttgacg actggacttc tcagagctgg tgctgtggtt tttagctgtc tgattgccaa
     3361 ccgaccagat ggaaacagcc gtccagctac accaaaaata tcaacacagg aaatgaaaaa
     3421 caaaccctca caaggtgatg cttttaacag tcgagtgcaa gaccttatca gctatgtggt
     3481 gaacatgggt ctgattgaca gactgcatgg ctgcttcctc tcagtgcaag gcccagtgga
     3541 tgagaatccc aaaatggcca catttctgca gcacgccgca ggcttcctac gtgggatgtg
     3601 tatgctatgc tttgctgtca ctggaaggtc ctccagcata tttgacaata atcaccagga
     3661 tcccacaggg ctgacagctg ctcttcaggc cacagacttg gctggagttc tacatatgct
     3721 ctactgtatc ctcttccacg gcaccatctc agacgccggc acgagtccca aggacagtta
     3781 cacccagaac accatccaag tagccattca gagtttacgt ttcttcaata gctttgcaat
     3841 tcttgatttg tctgcttttc agtctgttgt aggggcagag ggcttgtccc ttgcattccg
     3901 gcacatggct agctccttgc taggccactg cagccaagtg tcctgtgaaa gcctcctcca
     3961 tgaggtcatc gtctgtgtgg gctacttcac tgtcaaccac ccagataacc aggtgattgt
     4021 tcagtccggc cgccacccaa cggtgctgca gaagctctgc cagctgcctt tccagtattt
     4081 cagtgacccg aggctcatca aagtgctgtt tccttcgctt atcaccgcgt gtcacaacaa
     4141 ccatcagaac aagctcattc tggagcaaga gatgagctgt gttttactgg ccacattcat
     4201 ccaggacttt gcacagactc cgggtcacgt ggataaccag tcttcaagtc tcaaaggaaa
     4261 attccagaac cccgggaact acctggaact ggctaacaga tttcctcagc aggcctggga
     4321 agaagcccgg caatttttct tgaaaaaaga aaaaaaataa atgtttttta gctaattctg
     4381 tatttgagtc cctttgttag tgttttccat tgttccttga ggagcctctg atctgtttat
     4441 actctcctac tgtagatacc cctctgtgca ttgtttataa agactgttca tactggcctt
     4501 cctagctttg caaattgagt ttgtttcctt tgtgcataat attttggaat tgtttattac
     4561 ttccatgcta tgtaacttgt aattgtaata tggtaaagtt agacaaatat cattcttgta
     4621 atgaagtaac acagttttca gtgttgactt ttcacattaa gcagtacaaa tttgagaaag
     4681 tgttaagaat ttataagccc tgctttaagt ttttctttgg agttagagac ctgtgtaact
     4741 aacactttca gtaagccttt gtactatttg aaattacagc acctaaccac tggtcgggaa
     4801 cttcactggc agaaagcact gtgaactatt cgtgttgctg agctaaattt agcctctaaa
     4861 ataaattttt tgaaaatgag ggagtatcaa gtattttctt aaataattta cttgaaacaa
     4921 cacggagtaa aagaaacaat gagggtggcc atgtctctga atacagccag tgatgtgcac
     4981 cgctcctgat gggctgggcc acagggggcc ctcttcaccc acccagtgcg gagcctgaga
     5041 aatatttagc aattacaaga aagatctagc tgtggaaaac tgacccagaa acctaaagat
     5101 tgtcacagga agctgaacaa cacagcaaca acttacctag cattctagcc atttcttttt
     5161 tcaaacctca tggcactaca gttttgtgtg ttcaatgttt tttactgttt tacaaatcga
     5221 aagaaaataa aaaggtctaa tgtaagcca
//
