LOCUS       NM_011886               1576 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus secretory carrier membrane protein 3 (Scamp3),
            transcript variant 2, mRNA.
ACCESSION   NM_011886
VERSION     NM_011886.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1576)
  AUTHORS   Kunarso,G., Wong,K.Y., Stanton,L.W. and Lipovich,L.
  TITLE     Detailed characterization of the mouse embryonic stem cell
            transcriptome reveals novel genes and intergenic splicing
            associated with pluripotency
  JOURNAL   BMC Genomics 9, 155 (2008)
   PUBMED   18400104
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1576)
  AUTHORS   Toonen,R.F., de Vries,K.J., Zalm,R., Sudhof,T.C. and Verhage,M.
  TITLE     Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1
            targeting and SNARE complex formation
  JOURNAL   J Neurochem 93 (6), 1393-1400 (2005)
   PUBMED   15935055
REFERENCE   3  (bases 1 to 1576)
  AUTHORS   Ng,P., Wei,C.L., Sung,W.K., Chiu,K.P., Lipovich,L., Ang,C.C.,
            Gupta,S., Shahab,A., Ridwan,A., Wong,C.H., Liu,E.T. and Ruan,Y.
  TITLE     Gene identification signature (GIS) analysis for transcriptome
            characterization and genome annotation
  JOURNAL   Nat Methods 2 (2), 105-111 (2005)
   PUBMED   15782207
REFERENCE   4  (bases 1 to 1576)
  AUTHORS   Bell,A.W., Ward,M.A., Blackstock,W.P., Freeman,H.N.,
            Choudhary,J.S., Lewis,A.P., Chotai,D., Fazel,A., Gushue,J.N.,
            Paiement,J., Palcy,S., Chevet,E., Lafreniere-Roula,M., Solari,R.,
            Thomas,D.Y., Rowley,A. and Bergeron,J.J.
  TITLE     Proteomics characterization of abundant Golgi membrane proteins
  JOURNAL   J Biol Chem 276 (7), 5152-5165 (2001)
   PUBMED   11042173
REFERENCE   5  (bases 1 to 1576)
  AUTHORS   Fernandez-Chacon,R. and Sudhof,T.C.
  TITLE     Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic
            vesicle-specific forms implicate SCAMPs in multiple
            membrane-trafficking functions
  JOURNAL   J Neurosci 20 (21), 7941-7950 (2000)
   PUBMED   11050114
REFERENCE   6  (bases 1 to 1576)
  AUTHORS   Singleton,D.R., Wu,T.T. and Castle,J.D.
  TITLE     Three mammalian SCAMPs (secretory carrier membrane proteins) are
            highly related products of distinct genes having similar
            subcellular distributions
  JOURNAL   J Cell Sci 110 (Pt 17), 2099-2107 (1997)
   PUBMED   9378760
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AA939832.1, AC161600.6, AK160549.1 and AV092991.1.
            
            On Jun 19, 2015 this sequence version replaced NM_011886.2.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the 5' coding region, compared to variant 1. It
            encodes isoform 2, which is shorter than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160549.1, AK146204.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                AA939832.1         1-28
            29-32               AC161600.6         171211-171214
            33-111              AA939832.1         31-109
            112-1567            AK160549.1         3-1458
            1568-1576           AV092991.1         277-285
FEATURES             Location/Qualifiers
     source          1..1576
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.01 cM"
     gene            1..1576
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /note="secretory carrier membrane protein 3"
                     /db_xref="GeneID:24045"
                     /db_xref="MGI:MGI:1346346"
     exon            1..267
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..1251
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /note="isoform 2 is encoded by transcript variant 2;
                     secretory carrier-associated membrane protein 3"
                     /codon_start=1
                     /product="secretory carrier-associated membrane protein 3
                     isoform 2"
                     /protein_id="NP_036016.2"
                     /db_xref="CCDS:CCDS50959.1"
                     /db_xref="GeneID:24045"
                     /db_xref="MGI:MGI:1346346"
                     /translation="MAQSRDTGNPFPDSGELDNPFQDPAVIQHRPSQQYATLDVYNPF
                     ENREPPPAYEPPAPAPAPLPPPSAPSVQSSRKLSPTEPRNYGSYSTQASAAAATAELL
                     KKQEELNRKAEELDRRERELQHVALGGAGTRQNNWPPLPSFCPVKPCFFQDISMEIPQ
                     EFQKTVSTMYYLWMCSTLALLLNFFACLARFCVDTGSGSGFGLSMLWLLLFTPCSFVC
                     WYRPMYKAFRSDSSFNFFVFFFIFFVQDVFFVLQAIGIPGWGFSGWVTALVVVGSKPA
                     VAVLMLLVALLFTGIAVLGIVMLKRIHSLYRQTGASFQKAQQEFAAGVFSNPAVRTAA
                     ANAAAGAAENAFRAP"
     exon            268..345
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     exon            346..474
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     exon            475..595
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     exon            596..724
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     exon            725..884
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     exon            885..986
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1104
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1576
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1549..1554
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /note="hexamer: AAGAAA"
     polyA_site      1571
                     /gene="Scamp3"
                     /gene_synonym="Sc3"
                     /note="major polyA site"
ORIGIN      
        1 tcctcccccc cccccaactg aggcgcaggc gcagtccact gctgctgcgg gaatcttcgc
       61 gactcttccg gttgtttcaa ccaattggag cacagggaag cgagtggacc aagcacaccg
      121 gagggagttc tttgggccgc caccgccgta ctgccggggc aggggcgtgt agggcagggg
      181 cggccgggtt cacttgcaaa catggctcag agcagagaca ccgggaatcc attccccgac
      241 tccggcgagc ttgacaatcc ctttcaggac ccagctgtga tccagcaccg acccagccag
      301 cagtatgcca cgctggacgt ctacaacccc tttgagaacc gagagccccc accagcctac
      361 gagcctcctg ctccagcccc agcacctcta ccgccaccct cagctccctc tgtacagtcc
      421 tcaagaaagc tcagccccac agagcccagg aactacggct cctacagcac ccaggcctca
      481 gctgcagcgg ccactgctga gctgctgaag aagcaggagg aactcaaccg caaggcagag
      541 gagttggacc gccgggagcg agaactgcag catgtcgccc tgggtggtgc aggcactcga
      601 cagaacaact ggcctcccct accgtctttt tgccctgtaa agccttgctt tttccaagac
      661 atctctatgg agatacccca agaatttcag aagacggtgt ccaccatgta ctacctctgg
      721 atgtgcagca ctctggctct tctcctgaac ttcttcgcct gcctggccag gttctgtgtg
      781 gacaccggca gtggctcagg ctttgggctg tctatgctct ggctgctcct tttcactccc
      841 tgctcctttg tctgctggta ccgcccgatg tataaggctt tccggagtga tagttcattc
      901 aatttcttcg tttttttctt cattttcttc gtccaggatg tgttctttgt cctccaggcc
      961 attggcatcc cagggtgggg cttcagcggc tgggtgactg ctctggtggt ggtgggatcc
     1021 aaacctgccg tggcggtgct catgctgctc gtcgccctgc tcttcaccgg catcgcagtg
     1081 ctgggaatcg tgatgctgaa gcggatccac tccctgtacc gccaaacggg tgccagcttt
     1141 cagaaggccc agcaagaatt tgctgctggt gtcttctcca accctgcggt tcgaactgct
     1201 gctgccaatg cagctgccgg agctgctgaa aatgccttca gggccccttg acccctgctg
     1261 cacccgctgg gatgccctgg gcctgtcacc tgtgggaacc aagatagtcc ctatccctga
     1321 agtctctggg attcagggag ccatcaccac ttggtgactt ctatggggct cttcattcca
     1381 cagccatgac tttaatcctg acttgaggtg tggagagccc gctgtgactc agtcattatt
     1441 tgccttttat ctcccatctg gccacactgc tgccgccacc tctcacacaa ccccaacccc
     1501 agtttccttc tgctgtgcca aggatgtctt cttccgttat ttaaattaaa gaaaaaaaag
     1561 tgtaactgga actcac
//
