LOCUS       NM_001033288            2748 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus somatomedin B and thrombospondin, type 1 domain
            containing (Sbspon), mRNA.
ACCESSION   NM_001033288 XM_129714 XM_913968
VERSION     NM_001033288.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2748)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2748)
  AUTHORS   Schneider,A.J., Gawdzik,J., Vezina,C.M., Baker,T.R. and
            Peterson,R.E.
  TITLE     Sox9 in mouse urogenital sinus epithelium mediates elongation of
            prostatic buds and expression of genes involved in epithelial cell
            migration
  JOURNAL   Gene Expr Patterns 34, 119075 (2019)
   PUBMED   31669249
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC109269.17.
            
            On May 2, 2007 this sequence version replaced NM_001033288.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK137144.1, AK143251.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-284               AC109269.17        26078-26361
            285-479             AC109269.17        34960-35154
            480-570             AC109269.17        58449-58539
            571-747             AC109269.17        59735-59911
            748-2748            AC109269.17        62938-64938
FEATURES             Location/Qualifiers
     source          1..2748
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 4.89 cM"
     gene            1..2748
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /note="somatomedin B and thrombospondin, type 1 domain
                     containing"
                     /db_xref="GeneID:226866"
                     /db_xref="MGI:MGI:2684952"
     exon            1..284
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..865
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /note="RPE-spondin; somatomedin-B and thrombospondin
                     type-1 domain-containing protein"
                     /codon_start=1
                     /product="somatomedin-B and thrombospondin type-1
                     domain-containing protein precursor"
                     /protein_id="NP_001028460.1"
                     /db_xref="CCDS:CCDS14828.1"
                     /db_xref="GeneID:226866"
                     /db_xref="MGI:MGI:2684952"
                     /translation="MKTLWMVLCALARLWPGALAGCAEAGRCCPGRDPACFARGWRLD
                     RVYGTCFCDQACRLTGDCCFDYDRACPARPCFVGEWSPWSGCAGQCQPTTRVRRRSVR
                     QEPLNGGAPCPPLEERAGCLEYSSSQSQDCGHSFVPAFITSSVFNKKRIIQAVSPQWS
                     THTKDAGYCMEFKTESLTPHCALVNSPLTRWMQYLREGYTVCVDCQPPAMNSVSLRCS
                     GDGLDSDGNQTLRWQAIGNPRCQGTWKKVRRVEQCSCPDVHRFIFI"
     exon            285..479
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /inference="alignment:Splign:2.1.0"
     exon            480..570
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /inference="alignment:Splign:2.1.0"
     exon            571..747
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /inference="alignment:Splign:2.1.0"
     exon            748..2748
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1226..1231
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /note="hexamer: ATTAAA"
     regulatory      1239..1244
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /note="hexamer: ATTATA"
     polyA_site      1253
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /note="major polyA site"
     polyA_site      1261
                     /gene="Sbspon"
                     /gene_synonym="Gm106; Rpesp"
                     /note="major polyA site"
ORIGIN      
        1 gtcggaggag ccgagctctt gcccgaggct ctagctgggt ccgttcgcaa gtgtcgcggc
       61 agctctggcc atgaagaccc tgtggatggt gctgtgcgct ctggcgcggc tgtggcccgg
      121 ggccctggct ggctgtgcag aggccggccg ctgctgtcct ggccgggacc cagcctgctt
      181 cgcccgcggc tggaggctgg acagggtcta tggaacatgc ttctgtgacc aagcctgccg
      241 tctcaccggg gactgctgct tcgactacga cagggcgtgc ccagctcgcc cttgctttgt
      301 gggagaatgg agtccctgga gtggctgcgc aggtcagtgc cagcccacca cgcgtgtgcg
      361 caggcgttca gtgcgtcagg aaccactaaa cggaggggcg ccctgcccac ccctggaaga
      421 gagagctggc tgcctggagt actcgtcatc acagagccag gactgcgggc actcctttgt
      481 tcctgccttc ataactagct ctgtcttcaa caagaagaga ataatacaag cagtatctcc
      541 acagtggtct acacacacta aggatgctgg atactgtatg gagttcaaga cagagtccct
      601 gactcctcac tgtgctctgg tcaacagtcc cctgactcga tggatgcagt atctccgtga
      661 gggatacaca gtgtgtgtag actgtcagcc accagctatg aactctgtga gcctacgttg
      721 ttctggagat ggtctggact ctgatggaaa tcagactctt cgctggcaag ccattggcaa
      781 tcctcgatgt cagggaacct ggaaaaaagt gcgtcgagta gaacagtgct catgtccaga
      841 tgtgcaccgc ttcattttta tatagagcac ctgggagcga cttccgagca tgcgtgtgaa
      901 tgggccgagt attgacaagc tgcattcaaa gcttccgagg cctccaaaag ctgcgccagg
      961 gacctggact ctcgcattgc tacgctttgc cactgagaaa gaacatttag ggatagttct
     1021 caaggtagac cacagtctct tggtttttat ttttaatgag ttaaggactc gtactaaaag
     1081 ctcctatggc ctgtagactt ttaccttaca tttggtcaca gcatacatgt ctatactaga
     1141 atcactacca tgtgctccag tttggggcaa attgttgttt aaggcaccta tgttttctct
     1201 ttctctcacc ctccctcttt taaaaattaa aggttctcat tatatagcct gaagttcact
     1261 acgtagccag gctggcctct aattaataga catctgtctg cttttgtggg aagaacaggt
     1321 caagacagag tttctttgtg tagcctttgc catcctggaa cttgttctgt agatcaggct
     1381 gacctctaac tcagagatct cctgtttctg cctcccaact tctagtattc agggccacct
     1441 atacttaaga gcttctcact ttaaaaaaaa aaaacatata tgtgaacttt cacccataaa
     1501 gttcctatac tatttattac ccttataaat tctaaactag cttcaagtaa atcatcataa
     1561 ataattttcc acagggaaag ttgtcaaaat ttcaaaagat gttttataat gaaaagctat
     1621 aaacattttt aaggaagtaa aaaaaatttg gtttagatga aaagatcaaa tattcatgct
     1681 agatcaatag gactttctta aaaagttaca attttcatga cattttggca ccaaattagc
     1741 caactgcttc aattattagc attctatcat cattcatata taagatttct caaagtatag
     1801 aggctgaagc agaataagac atatctttta atgtctgact tcatgcttag ttaaaggtgc
     1861 tcgctagttt tctccctatg gcacagaggg tagaaaacac agattttcct gcaaacgtta
     1921 tgatctcctt cctactcaga gaatattagc tttacccttg gttgggagat aactgagttt
     1981 gtggctaagt ggcatggtgt gctcacaggc ctaggatggc aagctgtttc tcagcatctg
     2041 cagtcatctg gtccagcttc ctcatctggg actcgacttc agtgaagatc atcctgacta
     2101 tgcccaagac tccattatag gacctcagcc tggctttgtt ttgaagcagg cttaaaattg
     2161 aggatagttt ctttgaagaa ttgaatcaat acttaaatgg tataaatcct ttggtgtgac
     2221 taatcactca ctaacatagc taactaaaat gcagactttt tggtgccgat catttaacta
     2281 ctgtggccaa caagaagctt aaaggggtag caaatgtctc ctgatagtat ttctgatttt
     2341 atttttattt aactgccaaa ggtattttca tagaaaatta attttaacaa aaacctttaa
     2401 tttgggggct ggaaagttgg cttagcagtt aagtgtgctc attactctta cagaggactg
     2461 gggtttagtt ctcagcaccc agggaactac cggtagctca caactaccgg tagctccagg
     2521 atgtttggtc gggcactctg aggcataagt aaccacttaa gtgaatggaa agaggtatgc
     2581 aacttttagg tttaggtgag agatataagc ttacttatct tccttccctc ataaattatg
     2641 tgggtaacat agatgagaag gggggagggg cagtctcagc ttagcgactt taaatgtatc
     2701 atttttttct catgtaattg tcctcaaacc cactgtttac ttgaactt
//
