LOCUS       NM_177324               7159 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus SET binding factor 2 (Sbf2), transcript variant 1,
            mRNA.
ACCESSION   NM_177324 XM_001477215 XM_001478567
VERSION     NM_177324.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7159)
  AUTHORS   Mammel,A.E., Delgado,K.C., Chin,A.L., Condon,A.F., Hill,J.Q.,
            Aicher,S.A., Wang,Y., Fedorov,L.M. and Robinson,F.L.
  TITLE     Distinct roles for the Charcot-Marie-Tooth disease-causing
            endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and
            Schwann cell myelination
  JOURNAL   Hum Mol Genet 31 (8), 1216-1229 (2022)
   PUBMED   34718573
  REMARK    GeneRIF: Distinct roles for the Charcot-Marie-Tooth disease-causing
            endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and
            Schwann cell myelination.
REFERENCE   2  (bases 1 to 7159)
  AUTHORS   Ng,A.A., Logan,A.M., Schmidt,E.J. and Robinson,F.L.
  TITLE     The CMT4B disease-causing phosphatases Mtmr2 and Mtmr13 localize to
            the Schwann cell cytoplasm and endomembrane compartments, where
            they depend upon each other to achieve wild-type levels of protein
            expression
  JOURNAL   Hum Mol Genet 22 (8), 1493-1506 (2013)
   PUBMED   23297362
  REMARK    GeneRIF: Mtmr2 and Mtmr13 depend upon each other to achieve
            wild-type levels of protein expression. Mtmr2 stabilizes Mtmr13 on
            membranes, indicating that the Mtmr13 pseudophosphatase is
            regulated by its catalytically active binding partner.
REFERENCE   3  (bases 1 to 7159)
  AUTHORS   Berger,P., Tersar,K., Ballmer-Hofer,K. and Suter,U.
  TITLE     The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate
            AKT signalling
  JOURNAL   J Cell Mol Med 15 (2), 307-315 (2011)
   PUBMED   19912440
  REMARK    GeneRIF: data indicate that Mtmr2 and Mtmr13/Sbf2 play critical
            roles in the sorting and modulation of cellular signalling which
            are likely to be disturbed in Charcot-Marie-Tooth disease type 4B
REFERENCE   4  (bases 1 to 7159)
  AUTHORS   Robinson,F.L., Niesman,I.R., Beiswenger,K.K. and Dixon,J.E.
  TITLE     Loss of the inactive myotubularin-related phosphatase Mtmr13 leads
            to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice
  JOURNAL   Proc Natl Acad Sci U S A 105 (12), 4916-4921 (2008)
   PUBMED   18349142
  REMARK    GeneRIF: Mtmr13-deficient mice develop a peripheral neuropathy
            characterized by reduced nerve conduction velocity and myelin
            outfoldings and infoldings.
REFERENCE   5  (bases 1 to 7159)
  AUTHORS   Tersar,K., Boentert,M., Berger,P., Bonneick,S., Wessig,C.,
            Toyka,K.V., Young,P. and Suter,U.
  TITLE     Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2
  JOURNAL   Hum Mol Genet 16 (24), 2991-3001 (2007)
   PUBMED   17855448
  REMARK    GeneRIF: Mtmr13 deficient mice are animal models for Charcot Marie
            Tooth disease.
REFERENCE   6  (bases 1 to 7159)
  AUTHORS   Berger,P., Berger,I., Schaffitzel,C., Tersar,K., Volkmer,B. and
            Suter,U.
  TITLE     Multi-level regulation of myotubularin-related protein-2
            phosphatase activity by myotubularin-related protein-13/set-binding
            factor-2
  JOURNAL   Hum Mol Genet 15 (4), 569-579 (2006)
   PUBMED   16399794
REFERENCE   7  (bases 1 to 7159)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   8  (bases 1 to 7159)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 7159)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   10 (bases 1 to 7159)
  AUTHORS   Laporte,J., Blondeau,F., Buj-Bello,A., Tentler,D., Kretz,C.,
            Dahl,N. and Mandel,J.L.
  TITLE     Characterization of the myotubularin dual specificity phosphatase
            gene family from yeast to human
  JOURNAL   Hum Mol Genet 7 (11), 1703-1712 (1998)
   PUBMED   9736772
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154911.4, AC122921.2 and AC124472.4.
            
            On Apr 9, 2022 this sequence version replaced NM_177324.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-208               AC154911.4         203550-203757       c
            209-297             AC154911.4         149101-149189       c
            298-435             AC122921.2         166026-166163       c
            436-555             AC122921.2         141393-141512       c
            556-666             AC122921.2         139661-139771       c
            667-772             AC122921.2         137942-138047       c
            773-905             AC122921.2         128634-128766       c
            906-1014            AC122921.2         126700-126808       c
            1015-1128           AC122921.2         123819-123932       c
            1129-1206           AC122921.2         119095-119172       c
            1207-1320           AC122921.2         118257-118370       c
            1321-1449           AC122921.2         117755-117883       c
            1450-1548           AC122921.2         115645-115743       c
            1549-1753           AC122921.2         104993-105197       c
            1754-1863           AC122921.2         99250-99359         c
            1864-2013           AC122921.2         97597-97746         c
            2014-2082           AC122921.2         76101-76169         c
            2083-2253           AC124472.4         16646-16816
            2254-2510           AC124472.4         18952-19208
            2511-2683           AC124472.4         22112-22284
            2684-2757           AC124472.4         23123-23196
            2758-2953           AC124472.4         25193-25388
            2954-3081           AC124472.4         27472-27599
            3082-3257           AC124472.4         28883-29058
            3258-3403           AC124472.4         30110-30255
            3404-3602           AC124472.4         32542-32740
            3603-3799           AC124472.4         42991-43187
            3800-3940           AC124472.4         45785-45925
            3941-4015           AC124472.4         53416-53490
            4016-4200           AC124472.4         54706-54890
            4201-4377           AC124472.4         59312-59488
            4378-4479           AC124472.4         64069-64170
            4480-4665           AC124472.4         64834-65019
            4666-4792           AC124472.4         73981-74107
            4793-4920           AC124472.4         77757-77884
            4921-5154           AC124472.4         79574-79807
            5155-5259           AC124472.4         80716-80820
            5260-5453           AC124472.4         81911-82104
            5454-5541           AC124472.4         82619-82706
            5542-5673           AC124472.4         84491-84622
            5674-7159           AC124472.4         85284-86769
FEATURES             Location/Qualifiers
     source          1..7159
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 57.7 cM"
     gene            1..7159
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /note="SET binding factor 2"
                     /db_xref="GeneID:319934"
                     /db_xref="MGI:MGI:1921831"
     exon            1..208
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            209..297
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            298..435
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            436..555
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            556..666
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            667..772
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            773..905
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            906..1014
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1128
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1206
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1320
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1449
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1548
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1753
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1754..1863
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            1864..2013
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2082
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            2083..2253
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            2254..2510
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2683
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            2684..2757
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            2758..2953
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            2954..3081
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            3082..3257
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            3258..3403
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            3404..3602
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            3603..3799
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            3800..3940
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            3941..4015
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            4016..4200
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            4201..4377
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            4378..4479
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            4480..4665
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            4666..4792
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            4793..4920
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            4921..5154
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            5155..5259
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            5260..5453
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            5454..5541
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            5542..5673
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     exon            5674..7159
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7133..7138
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /note="hexamer: ATTAAA"
     polyA_site      7159
                     /gene="Sbf2"
                     /gene_synonym="4833411B01Rik; B430219L04Rik; mMTMH1;
                     Mtmr13"
                     /note="major polyA site"
ORIGIN      
        1 agtgagcgcc tcggttgtca aacatggctg aagcgccgct gctaccgcta cagccgccga
       61 agggaaaatg ctgagctcgc ccgggccggg tgggcggcgg cggcggcgag ggcggcgacg
      121 ggaacccgct tcccgggcgc ggcggcggcg gtcatggccc ggctggccga ctacttcatt
      181 gtggtaggct acgaccacga gaagccagca gggccaggag aaggtctggg gaaaataatt
      241 cagagattcc cacagcagga ctgggatgac acgcctttcc cacagggaat tgaattgttt
      301 tgtcaacctg gtggatggca cctgtccaga gagcggaaac agccaacatt ctttgtggtg
      361 gtcctaacag atattgactc agatcgacat tactgctcat gtctaacttt ctatgaggca
      421 gagatcaatc tccagggaac gaagaaggaa gagattgaag gtgaagaagt atctggttta
      481 attcaaccag cagaagtatt tgcccccaaa agcctggtgt tggtatccag attagactat
      541 ccagaaatct ttagggcctg cctgggtttg atctatactg tgtatgtgga cagcatgagt
      601 gtctccttgg aaagtctcat cgcaaatctt tgtgcttgcc ttgtcccagc tgctggaggg
      661 tctcagaagc tattttcctt gggtgcagga gacagacaac tgatccagac acctttgcat
      721 gacagccttc ctgtcacagg cactagtgtg gctcttttat ttcagcaatt aggcattcaa
      781 aacgtcctca acctcttctg cgcagtcctt acagaaaaca aggttctctt ccactctgca
      841 agcttccaga gactcagtga tgcctgtaga gccctggaat ctctaatgtt tcctctgaag
      901 tacagttacc cgtatatccc cattcttccg gctcagctcc tagaagtttt gagttctcca
      961 actccgttca ttattggcgt acactccatc tttaaaactg atgtccatga gcttttagat
     1021 gtaatcatag cagatttgga tggaggcact attaaaattc ctgaatgcat tcacctctca
     1081 tccctcccgg agcctcttct tcatcagact caatcagcac tttctctgat cttgcacccg
     1141 gatttggaag tagcagatca tgccttccct cctccacgaa cagctttatc ccactcaaaa
     1201 atgctggata aagaagttcg agcagttttc cttaggttat ttgcacaact gttccaagga
     1261 tacaggtcat gcctccagct tatccggatc catgccgagc ctgtgataca ctttcacaaa
     1321 acagctttct tggggcagcg tggcttggtt gagaatgatt tcctcactaa agtgctcaat
     1381 ggaatggcat ttgcaggttt tgtttcagaa agaggacctc cctatagagc ctgtgatctc
     1441 tttgatgagt tggtagcttt tgaagtagaa agaattaaag ttgaagaaaa gaatccactg
     1501 aagatgataa agcacatcag agaacttgct gagcagctat tcaaaaacga gaatccaaac
     1561 cctcatatgg cattccagaa agttccacgt ccaacagaag gatcccactt gagagttcat
     1621 attcttcctt ttccaaagat taatgaagcc cgggttcaag aactaataca ggaaaatctt
     1681 gctaagaacc agaatgcacc tcctgctaca cgaatagaaa agaaatgtgt agtgccagca
     1741 ggtccacccg ttgtttcaat aatggaaaaa gtgataacag tttttaacag tgcacagaga
     1801 ctggaagttg ttagaaactg catctcattc atatttgaaa ataaaacttt ggaaactgag
     1861 aagacccttc ctgctgcctt gagggccctt aaaggaaaag cagcaagaca gtgtctcact
     1921 gatgaactgg gcttgcacgt tcagcagaac cgggcaatac tggaccatca acagtttgac
     1981 tacataataa ggatgatgaa ctgtactcta caggattgtt caagtttaga agaatataac
     2041 atcgctgcag cattactccc cctgaccagt gctttctata ggaaacttgc ccctggagtc
     2101 agccagtttg cctacacctg tgtacaggac caccccattt ggacaaatca gcagttttgg
     2161 gagacaactt tttacaatgc agtacaggag caggttcgct ccctgtatct ctcagcaaag
     2221 gacgacaatc atatcccaca tctgaagcag aagcttcccg atggccagca tcaggagaag
     2281 acagccatgg acttggcagc cgagcagctt cgcctatggc ctaccctgag caagtcaact
     2341 cagcaggagc tggtgcagca cgaggagagc accgtcttca gccaggccat tcactttgca
     2401 aacctcatgg ttaacctgct cgttccactc gacacgagta aaaacaagct gcttcgagca
     2461 tccgctccag gagactggga aagtgggagc aacagcatcg tcacaaacag tattgcagga
     2521 agtgtagctg agagctatga tacagagagt gggtttgaag attcggaaaa cagtgatgtg
     2581 gccaactctg ttgtaaggtt cattgcccga tttattgaca aggtttgtac agagagtgga
     2641 gtgactcagg accacatcag gagcctccac tgcatgatac caggaattgt agctatgcac
     2701 attgagaccc tagaggcagt acatcgcgag agtagaagac ttccacctat ccagaagccc
     2761 aagattcttc gaccagctct actgccagga gaagaaattg tatgtgaagg tcttcgagtc
     2821 ctactagatc ctgatggtcg cgaagaagcc actggaggtc tcctcggagg tcctcagctc
     2881 ctgcctgcag aaggcgcctt gttcctcacc acatacagaa ttctctttag agggacaccg
     2941 catgaccagc tagttggtga acaaacagtt gtgcggagct ttcccattgc ttcaatcacc
     3001 aaggagaaga agataaccat gcagaaccag ctccagcaga gcgtgcagga agggttgcag
     3061 atcacatcag cgtctttcca gttgattaaa gtagcatttg atgaagaagt cagtccagaa
     3121 gtggtcgaca tctttaagaa gcagctgatg aagttccgtt accctcagtc cattttcagc
     3181 acctttgctt ttgctgctgg acaaactacc ccacaaatca ttttacccaa gcagaaagaa
     3241 aagaacacct ccttccgaac tttctcaaaa acaattgtga aaggtgccaa gaaggcagga
     3301 aaaatgacaa ttgggaggca gtatttatta aagaagagaa caggaacaat tgtggaagag
     3361 agagtaaatc gtcctgggtg gaatgaagaa gatgatattt ctgtttcaga tgatagtgaa
     3421 cttcccacaa gtacaacctt gaaggcctca gagaagtcga caatggaaca gttggtggaa
     3481 aaagcgtgtt tcagagatta tcagcggtta ggtttgggaa ccataagtgg caactcctct
     3541 cgttcaaaac cagagtattt ccgagtcact gcctccaaca ggctgtattc gctatgccgg
     3601 agctatcctg gccttttagt catacctcaa gctgtacaag acagtagttt accaagagta
     3661 gcccgctgct atcgacacaa tcgcctgccc gtcgtatgtt ggaagaactc gagaagtggt
     3721 actctgctcc tccgatctgg aggattccat gggaagggag ttgttggtct attcaagtca
     3781 cagaactccc ctcaagccgt ttctacctcc tctttagaat cttccagtag catagagcaa
     3841 gaaaagtact tgcaagcctt attgactgca gtcattgtcc atcagaaact cagaggcagc
     3901 agtactctca ctgtcagacc agcacttgct ctgtccccag tgcatgggta cagagacaaa
     3961 agtttcactc agtcaaatcc caaatcttca gctaaggaac cagttcataa tcaaggcgta
     4021 tgggcaagtc ttcgttccag cacccgtttg atcagctccc cgacatcctt cattgatgtt
     4081 ggtgccaggc tggcaggcaa ggaccactca gcctccttca gtaacagtac ctacctacaa
     4141 aaccaactct tgaaacgaca agccgccctt tatatatttg gtgaaaagtc acagctacgg
     4201 agctcaaagg tagaattcgc tttcaactgt gagtttgttc ctgttgagtt ccatgaaatc
     4261 cgacaagtga aagccagttt taagaagctg atgagagctt gtatcccaag taccatccct
     4321 acagactcgg aagtgacatt cctgaaggcc ctgggagatt ctgagtggtt cccacagctt
     4381 cacaggataa tgcagctggc tgtggttgtg tcagaagtac ttgagaatgg gtcttcagtg
     4441 tgggtgtgtt tagaagaagg ctgggacatc actacacaag tgacatccct ggcacagcta
     4501 ctcagtgacc ccttctacag gacaatcgca ggcttccgga cgctggtgga gaaggaatgg
     4561 ctctcttttg gtcataagtt cagccagcgc agcagcttgg cccttaactc tcagggcggt
     4621 ggctttgctc ccatcttctt gcagttctta gactgtgtgc accaggttca caaccagtat
     4681 ccaactgagt ttgaattcaa tctctattac ctaaagttct tggctttcca ttatgtgtct
     4741 aatcgcttta aaacatttct cctggattca gactatgaaa gactagaaca tggaacttta
     4801 tttgatgata aaggtgacaa acatgccaag aaaggagttt gtatctggga gtgtattgac
     4861 aagatgcaca cacggagtcc cattttcttc aattacttat actcaccggt ggaagtagag
     4921 gccctgaagc ctaatgtaaa tgtctccagc ctaaagaagt gggattacta cacagaagag
     4981 accctgtctg caggtccttc atatgactgg atgatgctga cccccaagca ctttccctat
     5041 gaggagtcag atgtagccgg aggagctggg ccccagagtc agaggaagac agtgtggcca
     5101 tgctatgatg atgtgacctg cagccagcca gatgccctca cgagactttt cagtgaaatt
     5161 gaaaaattgg agcataaatt gaatcaaact cctgagagat ggcaccagct atgggaaaaa
     5221 gtcaccacgg acctcaagga agagccaaga acagcccatt ccctaagaca ctcagcggga
     5281 tccccaggaa ttgcatctac caacgtgcct tcctatcaga agaggcctgc gctgcacccg
     5341 ctacaccgag gcctgggcga ggatcagagt accaccaccg ccccgtccaa tggtgtagag
     5401 cacagggcgg ccacacttta cagccagtac acatccaaga acgacgagaa cagatccttt
     5461 gaaggaacat tatacaaacg aggagcattg ctgaagggtt ggaaaccccg ctggtttgtt
     5521 ttagatgtca cgaaacacca gctgcgatac tatgattcgg gggaagacac gagttgtaaa
     5581 ggccacattg atctggctga agtagaaatg gttatccctg ccggccccag catgggagcc
     5641 ccaaagtata caagtgacaa ggctttcttt gatctcaaga ccagcaagcg agtgtataac
     5701 ttctgtgccc aggatgggca gagcgcccag caatggatgg acaggatcca gagctgcatc
     5761 tctgatgcct gatgcccagg atcagacaag cacgaaaggt agaggaactc actcatctgc
     5821 ctgacagggc gatgacggtc atcccagggc ctgaggttct gcttaccttg tcccctctgg
     5881 aagcagttgg catgtcacac aggtctgggt gggagccctg gccctccctc tccctgcagc
     5941 attccaacag gattgaagtg gagagggtgc ctctggacct gctgctgtca tgtaggcaag
     6001 gtggctccca cctgagtcct cctccatgaa gactgttctc caaagccata acttcaacaa
     6061 cttggaccac agaaatccaa accttcaaag gtcgctgtac accgaccgca taggtgtccc
     6121 atcagacaca cctcctccta ctgcctgatc cttgagatgt cggttccctg gtgctgccaa
     6181 aggtgctttc atggttcctg cccgggagct tcgcagcagg agacgtcact actcagtggc
     6241 aggcagagga ggttaacaat agcacagaat gacctgggcc agtgcaggaa acactgcttc
     6301 aaaccacgag tctctgagga cacagtgcct gggtcctgcg ttctctcctg ttccccacag
     6361 ctttctgtga agtaacaagc gtgcgagccc acagaacact agcactgaac taaccaggga
     6421 gccattggac aaactgagac acatgggaca ggccagcaca caggggacag gccagctaac
     6481 cagacagcac tgcttgtgag aagaactgct cctaaggtct cccagttacc ataaccttgt
     6541 ttgctccagc ctcaaactca aggatgcttc tcatctgtgg tgggcctgag cggccaccgc
     6601 tgccaccggg ccctagcaac ttggtcagtg tgtgtgtttt gaaatgttaa tatgttaaat
     6661 accaaactaa tatttcaaaa tatgtatata tgatttctat atcctgattt ttcagatagc
     6721 ctgcttataa tttaaaataa aaataactaa actgattcat aagattttag taataaaagg
     6781 ttgtttcctt tttaaataat aaaaactact ttgtagatta aaaataaatc aaattttcaa
     6841 attaaaaatt atcaacacac tagaaaatag aactgtatta atatataaga aattgggaaa
     6901 taaaaatgaa ggagtttttt atcatattca ttttataaat ttgccacctg tgaaatggtt
     6961 tttgcacatt acttgtattt tctttgtata tgaaataatt tttgtacttt gtagactctg
     7021 gagcccactg tcctctcggc tctttgaagc tgtgcccact actgcttttg taactggagt
     7081 cttttaactt ccatgacggc accgcctgcc gtatgttcac taaccaccca gaattaaatt
     7141 tatttcttaa gaaaaagaa
//
