LOCUS       NM_001170561            6268 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus SET binding factor 1 (Sbf1), transcript variant 1,
            mRNA.
ACCESSION   NM_001170561
VERSION     NM_001170561.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6268)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6268)
  AUTHORS   Mammel,A.E., Delgado,K.C., Chin,A.L., Condon,A.F., Hill,J.Q.,
            Aicher,S.A., Wang,Y., Fedorov,L.M. and Robinson,F.L.
  TITLE     Distinct roles for the Charcot-Marie-Tooth disease-causing
            endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and
            Schwann cell myelination
  JOURNAL   Hum Mol Genet 31 (8), 1216-1229 (2022)
   PUBMED   34718573
  REMARK    GeneRIF: Distinct roles for the Charcot-Marie-Tooth disease-causing
            endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and
            Schwann cell myelination.
REFERENCE   3  (bases 1 to 6268)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   4  (bases 1 to 6268)
  AUTHORS   Firestein,R., Nagy,P.L., Daly,M., Huie,P., Conti,M. and Cleary,M.L.
  TITLE     Male infertility, impaired spermatogenesis, and azoospermia in mice
            deficient for the pseudophosphatase Sbf1
  JOURNAL   J Clin Invest 109 (9), 1165-1172 (2002)
   PUBMED   11994405
  REMARK    GeneRIF: expressed at high levels in seminiferous tubules of the
            testis; mice that are nullizygous for Sbf1 exhibit male infertility
            characterized by azoospermia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160538.8.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158013.1, SRR10223971.15514.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-250               AC160538.8         11872-12121
            251-336             AC160538.8         18613-18698
            337-474             AC160538.8         19024-19161
            475-633             AC160538.8         19338-19496
            634-744             AC160538.8         19580-19690
            745-850             AC160538.8         20248-20353
            851-983             AC160538.8         20473-20605
            984-1092            AC160538.8         20706-20814
            1093-1206           AC160538.8         20890-21003
            1207-1284           AC160538.8         21111-21188
            1285-1398           AC160538.8         21526-21639
            1399-1527           AC160538.8         21711-21839
            1528-1626           AC160538.8         21922-22020
            1627-1831           AC160538.8         22098-22302
            1832-1944           AC160538.8         22386-22498
            1945-2094           AC160538.8         23224-23373
            2095-2163           AC160538.8         23642-23710
            2164-2322           AC160538.8         23805-23963
            2323-2591           AC160538.8         24038-24306
            2592-2764           AC160538.8         24406-24578
            2765-2838           AC160538.8         24658-24731
            2839-3034           AC160538.8         24806-25001
            3035-3162           AC160538.8         25213-25340
            3163-3341           AC160538.8         26232-26410
            3342-3478           AC160538.8         26519-26655
            3479-3686           AC160538.8         26755-26962
            3687-3883           AC160538.8         27282-27478
            3884-4021           AC160538.8         27563-27700
            4022-4099           AC160538.8         31154-31231
            4100-4281           AC160538.8         31607-31788
            4282-4461           AC160538.8         31871-32050
            4462-4563           AC160538.8         32679-32780
            4564-4749           AC160538.8         32854-33039
            4750-4876           AC160538.8         33112-33238
            4877-5007           AC160538.8         33314-33444
            5008-5238           AC160538.8         33517-33747
            5239-5346           AC160538.8         37153-37260
            5347-5558           AC160538.8         37367-37578
            5559-5646           AC160538.8         38074-38161
            5647-5778           AC160538.8         38240-38371
            5779-6268           AC160538.8         38458-38947
FEATURES             Location/Qualifiers
     source          1..6268
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 44.79 cM"
     gene            1..6268
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /note="SET binding factor 1"
                     /db_xref="GeneID:77980"
                     /db_xref="MGI:MGI:1925230"
     exon            1..250
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     CDS             196..5877
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /note="isoform 1 is encoded by transcript variant 1;
                     myotubularin-related protein 5; inactive
                     phosphatidylinositol 3-phosphatase 5"
                     /codon_start=1
                     /product="myotubularin-related protein 5 isoform 1"
                     /protein_id="NP_001164032.1"
                     /db_xref="CCDS:CCDS49699.1"
                     /db_xref="GeneID:77980"
                     /db_xref="MGI:MGI:1925230"
                     /translation="MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQG
                     IELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVESTQEVVCTDNAT
                     EKEEEADGGGQARLSSTAPAQPGQLFAPKTLVLVSRLDHAEVFRNSLGLIYAIHVEGL
                     NVSLENVIGNLLTCTVPLAGGSQRTISLGAGDRQVIQTPLVDSLPVSRCSVALLFRQL
                     GITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLE
                     VLSTPTPFIIGVNAAFQAETQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHNV
                     LSMVLDPELELADLAFPPPTTSASSLKMQDKELRAVFLRLFAQLLQGYRWCLHIVRIH
                     PEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRATDLFDELVAHEV
                     ARMRADESHPHRVLRHVQELAEQLYKNENPYPAVAMHKVQRPGEASHLRRTHRPFPRL
                     DEGTIQWIVDQAAAKMQGAPPAVKAERRSTVPSGPPMTAILERCSGPHINSARRLEVV
                     RNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAHELHLHVQQNRAVLDHQQFDFV
                     VRMMNCCLQDCTSLDEHGIASALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFW
                     EAMFYGDVQTHIRALYLEPSDGVSPTQETGEAQSQDDERSALDVASEQRRLWPTLSRE
                     KQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGDLESASNSLVTN
                     SMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVP
                     DIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGVG
                     GSGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRISVQTP
                     VDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRATFAFTLGS
                     AHTPGRPPRVTKDKGPSFRTLSRNLMKNAKKTIGRQYVTRKKYNPPGWEHRGQPPPED
                     QEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAK
                     SEPFRISPVNRMYAICRSYPGLLIVPQSIQDNALQRVSRCYRQNRFPVVCWRSGRSKA
                     VLLRSGGLHGKGVVGLFKAQNTPSPGQAQADSSSLEQEKYLQAVVSSMPRYADSSGRN
                     TLSSFSSAHMGGHVPSPRARVTTLSNPLAASASRWTASRGKWSSVRASGRSSGLGSDV
                     GSRLAGRDLLSTPHTNGAPPDSGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIE
                     VFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQISVLVVEL
                     LDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRG
                     AHTLAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHTSRRFRTFLLD
                     SDYERIELGLLYEEKGERRGQLACKSVWEYVDRLSKRTPMFYNYTYAPEDTEVLRPYS
                     NVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSR
                     PRVQPDAISRLLEELQRLETELGRPSERWKDTWDRVKAAQRLESRQDGRGTPSSLLVS
                     AVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTTSSSRQAARRSTSTLYSQFQTAE
                     SENRSYEGILYKKGAFMKPWKARWFVLDKTKHQLRYYDHRMDTECKGVIDLAEVEAVA
                     PGTPTIGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSDA"
     exon            251..336
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            337..474
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            475..633
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            634..744
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            745..850
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            851..983
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1092
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1206
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1284
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            1285..1398
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            1399..1527
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            1528..1626
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1831
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            1832..1944
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..2094
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            2095..2163
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2322
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            2323..2591
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            2592..2764
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            2765..2838
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            2839..3034
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            3035..3162
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            3163..3341
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            3342..3478
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            3479..3686
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            3687..3883
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            3884..4021
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            4022..4099
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            4100..4281
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            4282..4461
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            4462..4563
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            4564..4749
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            4750..4876
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            4877..5007
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            5008..5238
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            5239..5346
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            5347..5558
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            5559..5646
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            5647..5778
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     exon            5779..6268
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6200..6205
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /note="hexamer: TATAAA"
     polyA_site      6221
                     /gene="Sbf1"
                     /gene_synonym="2610510A08Rik; B230113C15Rik; mKIAA3020;
                     Mtmr5"
                     /note="major polyA site"
ORIGIN      
        1 gggcagaact gcgcaggctc ctgaagcgcc cgggcgggcc ggctggctgg gaagatggcg
       61 gcggaagccc tggtcagcgg cgccgcagag gagcgggccc ggggtgtccc aagtgtgcag
      121 cttagggcca gcgccgggcc atgagcgcgc cgccatcgaa ccctcgagcc gtggagcccg
      181 cctgcgcccc ttgccatggc gcggctcgcg gactacttcg tgctggtggc gttcgggccg
      241 cacccgcgcg ggagtgggga aggccagggc cagatcctgc agcgcttccc ggagaaggac
      301 tgggaggaca accctttccc ccagggcatt gagctgtttt gccagcccag tgggtggcag
      361 ctatgtcccg agaggaatcc accaactttc tttgtggctg tccttactga catcaactct
      421 gagaggcact actgcgcctg cttgaccttc tgggagccag tggagtccac acaggaagta
      481 gtgtgcactg acaatgccac ggagaaggag gaagaggcag atggaggagg ccaagcgcgg
      541 ctgtcatcca cagccccagc ccagcctggc cagctttttg cgccaaagac tctggttctg
      601 gtgtctcgac tggaccatgc cgaagtgttc aggaatagcc ttggtctcat ctatgctatc
      661 cacgtggaag gcctgaatgt gagcctcgag aatgtgatcg ggaacctgct cacatgtacc
      721 gtcccattgg ctggcgggtc tcagagaacc atctctttgg gggctggtga ccggcaggtc
      781 attcagactc cactggtaga ctcactgcct gtcagccgct gtagtgtagc cctgctcttc
      841 cgccagctgg gtatcaccaa tgtgctgtct ttgttctgtg ctgcccttac tgagcacaaa
      901 gtcctcttct tgtccaggag ctaccaacgt ctagcagatg cttgcagggg tctcttggca
      961 ttgctgttcc ctctcagata cagcttcact tatgtgccca tcttgccggc acagctgctg
     1021 gaagtcctta gcacacctac gcctttcatc attggggtca atgcagcctt ccaggcagag
     1081 actcaggagc tgctggatgt gattgttgct gatcttgacg gagggacagt gactgtccct
     1141 gagtgtgtgc acattccacc cctgccagag ccactacaaa gccagaccca caatgttctg
     1201 agcatggtcc tggatccaga actggagttg gctgaccttg ccttcccacc ccctacaaca
     1261 tctgcttcct ccctgaaaat gcaggacaag gagctccgtg ctgtctttct gcggctcttt
     1321 gctcagctcc tgcaaggcta ccgctggtgc ctgcacatcg tgcgcatcca cccagagccc
     1381 gtcatccgct tccataaggc agcattctta ggccagcgtg gactggtgga ggatgatttc
     1441 ctgatgaaag tattggaggg catggccttc gcgggctttg tatctgagcg tggggttccc
     1501 taccgtgcca cagacctgtt tgatgagctg gtggctcatg aggtagcacg gatgcgagca
     1561 gatgagagcc atccccaccg tgtcctgcgt catgtccagg aactggcaga gcaactttat
     1621 aagaatgaaa acccgtaccc agctgtggcg atgcacaaag tgcagaggcc aggagaggcc
     1681 agtcacctgc ggcggaccca ccggccattc ccccggctag atgagggcac aattcagtgg
     1741 attgtggacc aggctgcggc caagatgcag ggcgcacctc cagctgtcaa ggctgagcgg
     1801 aggagcactg tgccttcagg gccccccatg acggccatac tggagcgctg tagtgggcct
     1861 catatcaaca gtgcacgtcg cttggaggta gtacggaatt gcatctccta tgtgtttgaa
     1921 gggaaaatgc ttgaggcaaa gaagttgctt ccggctgtac tcagggccct gaaggggcga
     1981 gctgcccgtc gctgccttgc ccatgagctt cacctgcacg tacagcagaa ccgggcagtt
     2041 ctggatcatc agcagtttga ctttgtcgtc cgcatgatga attgctgcct gcaggattgc
     2101 acttccctgg atgagcatgg cattgcatct gcactgctgc ctttggtcac agccttctgc
     2161 aggaagctga gcccaggggt gacacagttt gcatacagct gtgttcagga gcacgtagtg
     2221 tggagcacac ctcagttctg ggaggccatg ttctatgggg atgtgcagac ccatatccga
     2281 gccctctacc tggagccctc tgatggcgtg agccccaccc aggagactgg ggaggcacag
     2341 tctcaggatg atgaacgatc tgccctggat gtggcttcag agcagaggcg cctgtggcca
     2401 accctgagcc gtgagaagca gcaggagctg gtacagaagg aggaaagcac tgtgttcagc
     2461 caggccatcc actatgccaa ccgcatgagc taccttctgc tgcctctgga cagcagcaag
     2521 agccggctgc tgcgggagcg ggcagggttg ggagacctgg agagtgccag caacagcctg
     2581 gtcaccaaca gcatggcagg cagtgtggct gagagctatg acacagagag tggctttgaa
     2641 gatgcagaga cgtgcgatgt ggctggggct gtagtccgct tcatcaaccg ctttgtggac
     2701 aaagtctgca cagagagtgg ggtcaccagc gaccacctca aaggactgca tgtcatggtg
     2761 ccagacattg tccagatgca cattgagacc ctggaggccg tacaccgtga gagcaagagg
     2821 ctgcccccga tacagaagcc caagctgctg aggccacgcc tgttgcctgg tgaggagtgt
     2881 gtcctcgatg gccttcgagt gtatctgctg ccagacgggc gtgaggaggg tgtaggaggc
     2941 agtggagggg gccctgctct actcccagct gagggtgctg tcttccttac cacataccgc
     3001 gtcatcttca cggggatgcc tactgacccc ctggtggggg agcaggtggt agtccgctcc
     3061 ttccccgtgg ctgccttgac caaggagaag cgcattagtg tgcagacccc tgtggaccag
     3121 cttctgcagg atgggctgca gcttcgttcc tgcacattcc agctgctgaa aatggccttt
     3181 gatgaggagg tgggatctga cagtgctgag ctcttccgaa agcagctaca caagcttcgg
     3241 tacccaccag acatcagggc cacctttgca ttcacacttg gctcagctca cacacctggc
     3301 aggccgccac gggttaccaa ggacaagggt ccttcattca gaaccctatc ccggaacctg
     3361 atgaagaatg ctaaaaagac cattgggcgg cagtatgtta ctcgtaagaa gtataacccc
     3421 cctggctggg agcatcgggg ccagccaccc cctgaggacc aggaggacga gatctcagtg
     3481 tcagaggagc tggagcctag cacactgacc ccgtcctcag ccctgaagcc ctctgaccgc
     3541 atgaccatga gcagcctggt ggaacgggca tgttgccgtg actaccagcg ccttggacta
     3601 ggtaccctga gcagcagcct gagccgggcc aagtctgagc cctttcgcat ctctcctgtt
     3661 aatcgcatgt atgccatatg tcgcagctat ccaggattgc tgattgttcc ccagagcatc
     3721 caggacaacg ccctgcagcg tgtatcccgc tgctaccgcc agaaccgctt ccctgtggtc
     3781 tgctggcgca gtgggcgctc caaggctgtc ttgctacgct ctgggggcct gcatggcaaa
     3841 ggtgttgttg gtctcttcaa ggcccagaat acaccttctc caggccaggc ccaggccgac
     3901 tccagcagcc tggagcaaga gaagtacctg caggctgtgg tcagctccat gccacgttat
     3961 gctgactcat caggacgaaa cacactgagt agcttctcct cagcccacat gggtggccat
     4021 gtgcccagcc cccgagccag ggtcaccacg ctgtccaacc ctttggcggc ctcggcctcc
     4081 agatggactg cgtcccgagg gaaatggagc agtgtccgag ccagtggtcg aagcagtggt
     4141 cttggttctg atgtgggctc tcggctagct ggcagagatc tcctcagtac tccccacacc
     4201 aacggagctc cacctgattc tggttttcta cggccacagc gtgcagccct ctacatcatt
     4261 ggtgacaaag ctcagctcaa gggtgtgcgc ccagatccct tgcaacagtg ggagctggta
     4321 cctattgaag tatttgaggc aaggcaggtg aaagccagct tcaagaaact attgaaagcc
     4381 tgtgtgcctg gttgccctgc cactgagccc agcccagcct cttttctgcg ctcactggag
     4441 gactcagaat ggctgatcca gatccacaag ctgctgcaga tatcggtgct ggtagtggag
     4501 ctgctcgact ctggctcctc tgtcctggtg agcctggagg acggctggga catcaccact
     4561 caggtggtat ccttggtgca gctgctctca gaccccttct accgcactct ggaaggcttc
     4621 cgactgctag tggaaaaaga gtggctgtcc tttggccatc gtttcagcca ccgcggggcc
     4681 cacaccctag ctgggcagag cagtggcttc acacccgtct tcctgcagtt cctggactgt
     4741 gtacaccagg tccatttgca gttccccatg gagtttgagt tcagtcagtt ctacctcaag
     4801 ttccttggtt accaccacac atcccgccgt ttccggacct tcttgctgga ctctgattat
     4861 gagcgtattg agctggggct gctgtatgag gagaagggtg aacgcagggg tcagctggcc
     4921 tgcaagtcag tgtgggagta tgtagaccgg ctaagcaaga ggacccccat gttctacaac
     4981 tacacatatg cacccgagga cacagaggtg ctgcgaccct acagcaatgt gtccaatctg
     5041 aaggtgtggg atttctacac tgaggagacg ctggctgagg ggccccctta tgactgggag
     5101 ctggcccagg gaccccctga gcctccagaa gaggaacgtc ctgatggagg tgctccccag
     5161 agcaggcgcc gtgtggtatg gccatgctat gacagccgtc ctcgagtcca gcctgatgcc
     5221 atctcacgtc tgctggagga gctgcagcgc ttggagacag agttaggtcg gccttctgaa
     5281 cgctggaaag acacctggga ccgggtgaag gctgctcagc gccttgaaag ccggcaagat
     5341 ggacgtggta cccccagctc acttctggtg tcggctgtgc cccaccaccg ccgctcgcta
     5401 ggcgtctatc tacaggaggg gcctgtgggc tctactctta gcctcagcct ggacagtgac
     5461 cagagcagtg gctcaaccac atctagctct cggcaggccg cccggcggag caccagcacc
     5521 ctgtacagcc agttccagac agctgagagt gagaacaggt cctatgaggg catcctatac
     5581 aagaaggggg ccttcatgaa gccctggaaa gcccgttggt ttgtcctaga caagaccaag
     5641 caccagctgc gatactatga ccaccgaatg gacacagaat gcaagggtgt cattgacctg
     5701 gcagaggtgg aagctgtggc acctggcaca cccactatag gtgcccctaa gactgtggat
     5761 gagaaggcct tctttgatgt gaagacaaca cgtcgcgttt acaacttctg tgcccaggat
     5821 gtgccctcag cccagcagtg ggtggaccgg atccagagct gcctgtcgga tgcctgaccc
     5881 ctcccggccc tgcccgggct gctctgcttc cagtcgttac agaccactag gggtgggcag
     5941 ggccgccccg gccatgttta cagccccggc cctcgacagt atttgaggcc ctgagccccc
     6001 ccagcacttg tgtgtacagc ccccgccccg ccccacctgg ccagctctaa cttattgtgg
     6061 tgtcatggct gagccgttta gggacgcggc catggtacag ccctgccctg ggcttgtaaa
     6121 tagtccaccc tacccggccc atcagtgtgc tggccctggc cggctggctg tgctaagttg
     6181 tttctagaac cagagtctat ataaagagag aactaacgac acaattgtac gcctgcatca
     6241 gcactgcatc agactgtggg tctgccca
//
