LOCUS       NM_026432               1883 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus store-operated calcium entry-associated regulatory
            factor (Saraf), mRNA.
ACCESSION   NM_026432
VERSION     NM_026432.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1883)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1883)
  AUTHORS   Gataulin,D., Kuperman,Y., Tsoory,M., Biton,I.E., Nataniel,T.,
            Palty,R., Karbat,I., Meshcheriakova,A. and Reuveny,E.
  TITLE     Store-operated Ca2+ entry regulatory factor alters murine metabolic
            state in an age-dependent manner via hypothalamic pathways
  JOURNAL   PNAS Nexus 2 (3), pgad068 (2023)
   PUBMED   37007714
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1883)
  AUTHORS   Wang,Y.M., Xu,W.J., Xiang,L.L., Ding,M., Zhang,J.J., Lu,J.Y.,
            Xie,B.J. and Gao,Y.D.
  TITLE     Store-operated calcium entry-associated regulatory factor regulates
            airway inflammation and airway remodeling in asthma mice models
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 321 (3), L533-L544 (2021)
   PUBMED   34231388
  REMARK    GeneRIF: Store-operated calcium entry-associated regulatory factor
            regulates airway inflammation and airway remodeling in asthma mice
            models.
REFERENCE   4  (bases 1 to 1883)
  AUTHORS   Sanlialp,A., Schumacher,D., Kiper,L., Varma,E., Riechert,E.,
            Ho,T.C., Hofmann,C., Kmietczyk,V., Zimmermann,F., Dlugosz,S.,
            Wirth,A., Gorska,A.A., Burghaus,J., Camacho Londono,J.E.,
            Katus,H.A., Doroudgar,S., Freichel,M. and Volkers,M.
  TITLE     Saraf-dependent activation of mTORC1 regulates cardiac growth
  JOURNAL   J Mol Cell Cardiol 141, 30-42 (2020)
   PUBMED   32173353
  REMARK    GeneRIF: Saraf-dependent activation of mTORC1 regulates cardiac
            growth.
REFERENCE   5  (bases 1 to 1883)
  AUTHORS   Lodder,E.M., Scicluna,B.P., Beekman,L., Arends,D., Moerland,P.D.,
            Tanck,M.W., Adriaens,M.E. and Bezzina,C.R.
  TITLE     Integrative genomic approach identifies multiple genes involved in
            cardiac collagen deposition
  JOURNAL   Circ Cardiovasc Genet 7 (6), 790-798 (2014)
   PUBMED   25217174
REFERENCE   6  (bases 1 to 1883)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY135425.1, AK007787.1 and AI841528.1.
            
            On Mar 5, 2019 this sequence version replaced NM_026432.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC013497.1, SRR7345562.2912245.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-362               BY135425.1         17-378
            363-1879            AK007787.1         306-1822
            1880-1883           AI841528.1         16-19               c
FEATURES             Location/Qualifiers
     source          1..1883
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 20.9 cM"
     gene            1..1883
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /note="store-operated calcium entry-associated regulatory
                     factor"
                     /db_xref="GeneID:67887"
                     /db_xref="MGI:MGI:1915137"
     exon            1..258
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            259..437
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            438..837
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            838..976
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1131
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1883
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1837..1842
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /note="hexamer: AATAAA"
     regulatory      1842..1847
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /note="hexamer: ATTAAA"
     polyA_site      1857
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
                     /note="major polyA site"
     polyA_site      1883
                     /gene="Saraf"
                     /gene_synonym="1810045K07Rik; Tmem66"
ORIGIN      
        1 agtgacgtca gattggcgca ggacaaagta acgtcgcgtc ttgctgctgt caggtggtcc
       61 cttttatggt gggttcctgt ggtcgctgcg cagcggctgg ccgacttccg cagcgggtct
      121 cgggccaccg agcgccgtct tcacccagcg ccatggctgt ggccgctgtc ggccgcccga
      181 gagccctgcg ctgcccgctg ttgctcctgc tgtcactcct gctggtagcc ggccctgcgc
      241 tgggctggaa cgaccctgac agaatactct tgcgggatgt gaaagctctt accctctact
      301 ccgaccgcta caccacctcc cggaggctgg accctatccc acagttgaag tgtgttggag
      361 gcaccgccgg ttgtgaggcc tataccccca gggtgataca gtgccagaac aaaggctggg
      421 atggctacga tgtacagtgg gaatgtaaga ccgacttgga tattgcatac aaatttggca
      481 aaactgtggt gagctgtgaa ggctacgagt cctctgaaga ccagtatgtc ctcaggggtt
      541 cctgcggctt ggagtacaac ttagattaca cagagctggg cctgaagaaa ctgaaggagt
      601 ctggaaagca ccagggcttc tctgattatt atcacaagct gtactcctca gattcctgtg
      661 gctttattac cattgcagta ctgtttgttc tcgcctttgc ggtttacaag ctgttcctca
      721 gcgatggcca ggggtcgcct ccgccgtatt ctgagcaccc gccatactca gagcactctc
      781 agaggtttgc cagtgccgca ggggcgcctc ctccgggctt taagtcggag ttcacaggac
      841 cacagaatac tggctatggt gcaagctctg gcttcgggag tgcttttgga ggccaaggct
      901 atggcagttc agggccgggg ttctggtctg gcctgggagc tggaggactg cttgggtatt
      961 tgtttggcag caacagagcg gcgacgcctt tctcagactc gtggtaccat ccagcctacc
     1021 ctccttccca ctctggggcc tggaacagtc gggcctactc acccctgggt ggaggcgcag
     1081 ggagctattg tgcatcctct aatgcagact cgagaaccag aacagcatca ggatatggtg
     1141 gcaccagaag acggtaaaat aggaaattga aggcaaacac tggatgcaaa gtttctgatt
     1201 tgtcatcacc atctctttaa cacctggcta atgggaataa ccaaaagttg tgtggtgttt
     1261 ggtccttgtg tagcttttcg tgtcccgttg tttgtggcca agagttgata tgtgacaaaa
     1321 tgctatggtt tgtatgataa tgtaacatgc agttcaaagc gatggccact gtggaatgct
     1381 gacattgtgc ttgtgtctca agcctttcat accagagggg gcattaggaa tggagcaccc
     1441 tcctgctgag actgagcaca gaccgcttga gctaggtggc tttggaccat gagtcattcc
     1501 ctcgtagaaa caacgatcct ctattggata ttaaaacact tggtgtttgc tgttcttcaa
     1561 acatttaagc ccagtgccga ctactaatta tgctgatttg tgggttgcaa tcgcttgatc
     1621 agtagagctt ggacccttct gtggtggtca gcgcctgggg attctgacct ttcacaggaa
     1681 gggtagaaag caaacgacat gcacagaagg cttggaaccg ctagacgtca gttttcaggt
     1741 ggtagcattc agacgcaaaa gcatggagtt ctctgtggag tcttaaactg tcagatgttg
     1801 ttgtgacatt ttgttttagc cttacattaa tatgacaata aattaaaaag acaggaagta
     1861 ttcttgttct ttgtactgct gaa
//
