LOCUS       NM_001081168            5839 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus SAP30-like (Sap30l), transcript variant 1, mRNA.
ACCESSION   NM_001081168 XM_203577
VERSION     NM_001081168.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5839)
  AUTHORS   Vincentz,J.W., Firulli,B.A., Toolan,K.P., Arking,D.E.,
            Sotoodehnia,N., Wan,J., Chen,P.S., de Gier-de Vries,C.,
            Christoffels,V.M., Rubart-von der Lohe,M. and Firulli,A.B.
  TITLE     Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA
            Transcription Factor Binding and Disrupts Conduction System
            Development and Function
  JOURNAL   Circ Res 125 (6), 575-589 (2019)
   PUBMED   31366290
REFERENCE   2  (bases 1 to 5839)
  AUTHORS   Streubel,G., Fitzpatrick,D.J., Oliviero,G., Scelfo,A., Moran,B.,
            Das,S., Munawar,N., Watson,A., Wynne,K., Negri,G.L., Dillon,E.T.,
            Jammula,S., Hokamp,K., O'Connor,D.P., Pasini,D., Cagney,G. and
            Bracken,A.P.
  TITLE     Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells
            required for self-renewal
  JOURNAL   EMBO J 36 (15), 2216-2232 (2017)
   PUBMED   28554894
REFERENCE   3  (bases 1 to 5839)
  AUTHORS   Smith,K.T., Sardiu,M.E., Martin-Brown,S.A., Seidel,C.,
            Mushegian,A., Egidy,R., Florens,L., Washburn,M.P. and Workman,J.L.
  TITLE     Human family with sequence similarity 60 member A (FAM60A) protein:
            a new subunit of the Sin3 deacetylase complex
  JOURNAL   Mol Cell Proteomics 11 (12), 1815-1828 (2012)
   PUBMED   22984288
REFERENCE   4  (bases 1 to 5839)
  AUTHORS   Munoz,I.M., MacArtney,T., Sanchez-Pulido,L., Ponting,C.P., Rocha,S.
            and Rouse,J.
  TITLE     Family with sequence similarity 60A (FAM60A) protein is a cell
            cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase
            complex
  JOURNAL   J Biol Chem 287 (39), 32346-32353 (2012)
   PUBMED   22865885
REFERENCE   5  (bases 1 to 5839)
  AUTHORS   Jurecic,R., Nachtman,R.G., Colicos,S.M. and Belmont,J.W.
  TITLE     Identification and cloning of differentially expressed genes by
            long-distance differential display
  JOURNAL   Anal Biochem 259 (2), 235-244 (1998)
   PUBMED   9618202
REFERENCE   6  (bases 1 to 5839)
  AUTHORS   Zhang,Y., Sun,Z.W., Iratni,R., Erdjument-Bromage,H., Tempst,P.,
            Hampsey,M. and Reinberg,D.
  TITLE     SAP30, a novel protein conserved between human and yeast, is a
            component of a histone deacetylase complex
  JOURNAL   Mol Cell 1 (7), 1021-1031 (1998)
   PUBMED   9651585
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732587.8.
            
            On Mar 7, 2023 this sequence version replaced NM_001081168.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784649.877210.1,
                                           SRR10223970.13197.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-677               AL732587.8         34536-35212
            678-800             AL732587.8         38967-39089
            801-899             AL732587.8         40947-41045
            900-5839            AL732587.8         42865-47804
FEATURES             Location/Qualifiers
     source          1..5839
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 35.27 cM"
     gene            1..5839
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /note="SAP30-like"
                     /db_xref="GeneID:50724"
                     /db_xref="MGI:MGI:1354709"
     exon            1..677
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /inference="alignment:Splign:2.1.0"
     CDS             480..1028
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /note="sin3 corepressor complex subunit SAP30L;
                     sin3A-associated protein p30-like protein; sin3-associated
                     protein p30-like"
                     /codon_start=1
                     /product="histone deacetylase complex subunit SAP30L"
                     /protein_id="NP_001074637.1"
                     /db_xref="CCDS:CCDS36160.1"
                     /db_xref="GeneID:50724"
                     /db_xref="MGI:MGI:1354709"
                     /translation="MNGFSTEEDSREGPPAAPAAAPGYGQSCCLIADGERCVRPAGNA
                     SFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKASDDGGDSPEHD
                     ADIPEVDLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYF
                     IYMVKSNRSRLDQKSEGSKQLE"
     exon            678..800
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /inference="alignment:Splign:2.1.0"
     exon            801..899
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /inference="alignment:Splign:2.1.0"
     exon            900..5839
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1147..1152
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /note="hexamer: AATAAA"
     polyA_site      1175
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /note="major polyA site"
     regulatory      5811..5816
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
                     /note="hexamer: AATAAA"
     polyA_site      5839
                     /gene="Sap30l"
                     /gene_synonym="2310079P12Rik; L55"
ORIGIN      
        1 gcactgttgt ggtgcggcgc gtcgggcggg cggcggccgg ggcggcccag gggctgccgc
       61 ggggactcgg ggcgccgccg agcggccagg cgctggggcg gcccgagcac accgcggggc
      121 ccggacacgg caggttcgag gccgggcccc cgcgcgggga gccacggggt ggagactttg
      181 ccgcgcggcg cggagcaggc gggagccggc gggggcctcg ggagccccag ggcggccggg
      241 cccggatccc gggggaagcc tcgtgagccc cggccggagc ctcggcgtgt gcatccccgc
      301 cggggcccgg gctgcaggag cacagagcag ccgggcctcg cggagctcgg agcgcgcctg
      361 acccagggcg caccgtggga cccgggcgcg gggctggcga agagctgccc cgcggggcta
      421 gcagccgcgg agtggcctac aggggtcctc ccccggaggg gccgggccgg ggcggggaga
      481 tgaacggctt cagcacagag gaggacagcc gcgaagggcc ccctgccgcc cccgccgccg
      541 ccccgggcta cggccagagc tgctgcctca tcgcggacgg cgagcgctgc gtccggcccg
      601 cgggcaacgc ctccttcagc aagagggtgc agaaaagcat ctcgcagaag aaactcaagc
      661 tggacataga caagagcgta aggcacctgt atatctgcga cttccacaaa aatttcatcc
      721 agagcgtccg aaataaaagg aagaggaagg caagtgacga tggcggagac tcccccgagc
      781 acgatgctga catccctgag gttgatctgt tccagctgca ggtgaacacg ctccgacgtt
      841 acaaacggca ctataagctg cagaccagac caggcttcaa caaggcccag ctagcagaga
      901 ctgtgagccg acacttcagg aacataccag tgaatgagaa agagacgctt gcctatttca
      961 tctacatggt gaagagtaac aggagcagac tggaccagaa gtcagagggc agcaagcagc
     1021 ttgagtgagc tacagccacc tgcccgtgtg aggtgggggc cgtgatgaaa ggacagccgg
     1081 gtactgcttg atgacaggtg gcctctgcaa catctcagcc aataaggact gttcatatct
     1141 actgtaaata aagtttgaat gatggatact gtaaatgtct cggtcaggag gattatattc
     1201 tcacaggtta gcatgtgtgt aaaaagactt taagatatct gctcagactg ggaggaaaaa
     1261 aaaccagtgt tataaaagga gttttaaaac cgtgtctaga gtgctcagca aggctttaaa
     1321 tcagttctcc tagaaatgct gggtgatacg catcttggcc atcaccatgc agtcccaggc
     1381 tgtcacaagc aaggcccagc cctggcagcg tggctcggtg acagtggaat tacagagtag
     1441 gcccatgttt gcgctgaccc ttgcccactg ggaacagagg gatgtcactt tattgcaagt
     1501 tttgccattt agtagcaaat cagttggaca ctagctccca ccttgccctg tgacctgtac
     1561 acagtggacg ctcagagtgt gctggccaag agctgtcgca gctacgcagc ttctgcttca
     1621 cccctcccac cactgagact ggggctttgt gttctctctg cttaaccact agaggtggag
     1681 gacaggctgc ccctccacaa gaagtccagg caagtgagga tctcggcaca gttgcacctg
     1741 caaaactgtt gagattccag catcaacaca aagacatcac aggctggcca tgatggtgca
     1801 tgctttagtc ccaccattcc agagaatgag acaggatagt gagctcaagg gtaacctggg
     1861 ctaaagaccc tatctcagaa aacagtgaac ctcaggatgg ctcagtaggc aaagacactt
     1921 gctgccatgc ctgatgacct gagttcagtt cctggccatg tagcagactg tcccctgaca
     1981 gacacacaca cacacacaca aaataagtga tttattgttt ttaaactata aacaaaacca
     2041 tagccttcca tagcagtctt tgcattttac ccagagtaag gtgtatagca tgacctgcat
     2101 gcccctggca gtgagcgctc tgatggcagg gatggggcgt ccgggctcgg gtttctggtc
     2161 tttagtacac agtctgcagg agagctgcca agtccctgtg atccagctcc gaagcccagc
     2221 tctggaaaga cagtgtggct gggctcggct ccttggtcct aggaggcagg agatcatgag
     2281 gctaggcaag aaaagccact gccacctcaa gttcagggga aaaaatcaga atcggcctcc
     2341 tttggggaga atgcttacta aggtaatttt ttcagtatta aattttgtcg ttgttcaaat
     2401 cagacccttc tatctagttc tctcaaaacc agaagcaccc tggaaagcag agctctcttg
     2461 tacaaagaat tgtatagaat ttccagtcag tttgtggggt aaaaggtgtg tgtaggagga
     2521 taagaaagat tcctaatttc caactatcct gtatgtattg ggccaaatgt ctcatctccc
     2581 tattccactt caattctgag tttttcttaa gtcctaacag aacagaggcc tggtctgaca
     2641 gttttaatgt ctcccaggtg gcttgcctga gcgccatctc agagcagaac taaccccaca
     2701 ctgagtgagt ggaggaatgt gtgatggttt ccctctatgg agcagagcgt cacgcttctg
     2761 tggagtggga acagggccct tcgtgttact aacatgcagt gttccattac ggctgagctc
     2821 ccaagaacac tcaaaatgca gtcctgagcc tccgtgcaga agttggtctc cctcctacca
     2881 cggatggaaa caacaggaga gcccaggcga agctggtgtc tgagggcaaa tggaatcttt
     2941 aacttaaccg gccctgtgga aagtgtctta tcaagaagaa aatgtagctt tctaatactt
     3001 taaccaaaac tgttagcatg taagccatgt gattgtttct ttaaaatcta gtttcctgtg
     3061 aagaggctca cttctgggca agatgtggca ttaggctccc tctagtccac gttctaagtc
     3121 cagatccaag ctggggagtg tctgccctcc agccagatcc cacctcagaa tccttgtcct
     3181 ctgatgccag cagccttgga gaagtagaga cctgggctat cattttcacc ctttcacaac
     3241 agatcgcctg agagaaaagg caaagctatt tgaacatgct gtgtcatgaa gtgtgctgtg
     3301 tcattggagc agcagtccct ggcctcccat ctccctgcct agtcatggcc aagaacccac
     3361 tgccttcaag aaaggcccaa gcctggctta gggagcagca gggattattg agagagtagt
     3421 gcttatctag gctgcttgta ttttcatatc accggccatg cctgcctccc tcacacatgc
     3481 atgcgcgtgc gcacacacgc gcgcacacac acacactcat ctgtgatggc tcagcatggt
     3541 ctctctactt ggtgcttctt gacagaactg gaatttcaag cccagaagtg gtatggcttc
     3601 ctgtctctga tccagcctgg tgtggttctt caatacaccc tgaaggggtc acatggagac
     3661 acccttagcc tgccattcat ttggggcttg aaaattttta caacacaaat gatcagaatt
     3721 ctctcatctc atggaactaa ctgagagaga gagagagaga gagagagaga gagagagaga
     3781 gagagagaga gagagagaga gagagagaga gaaatggtaa accaaaattc caggtgggga
     3841 ttgtgactct gtgaaggaac ttggcttctg tgtcctgcat gtttctgcca taagtagcta
     3901 tactcataat agcctctcat agagcaaagc tttaatgtgc atgcgtgtgt ttgtgtgtgt
     3961 gtgtgtttgc acacttcctg ttaatatttt accaagtgac tgcctggttt gtggtggcag
     4021 gatagcttgt ccactgcagc aggtggtccc tggcatagtc ccaaagaagt tgcctcattg
     4081 ataccatctg aaagctctct gtggtccaag ggatccaaag gttgcaaaga gtcttgagtc
     4141 ctcccgtcca gcttctccat tggtgctgac attctgccta tacccatccc agccaagaag
     4201 cagtctgcac ctggtcacct ccaaggacag agagctcact acctcctagg gaagactgtt
     4261 ctgttgttag cttctggctt ttccaggctc tctaagttgg ggggccatgt gggcagagtc
     4321 tctcaatggg caaaggaccc agtcttagca ttgtctcaca cattgtatcc tttttgcaaa
     4381 agggaacagc tggatacaat gtgttttcac gccccctgac ccctcagtat gggtctattg
     4441 gtcttggttc catgttggaa gtgttggaga aatccctcag cctaactcat gccaaagttg
     4501 ccaggggggg gcaccagcct gctaacaaga gtccacatta atggaggttg tagtcccatg
     4561 ctggccacac aaaatctgtg gcatctctga ggggtaacat tagctggagg gttctaacta
     4621 aacagcatag ggctttgcct ggagtttaag gtccctggct tgccgagggc tcgtctcttc
     4681 tggttcccat gtggacgcag tcactctgaa agctgaaggt actgttccac atagtcactt
     4741 aaggttgcta tcccattgtc tttctaagtg aatgagggaa agactttccc cagagatctg
     4801 tcaaggtcat gttagggagg ggcctttatg gccttcattt gcacactgta gacttttgct
     4861 tgtgacaggt gacctaaaat aagctgctct ggaaagtctc agagcttatc cctgggagct
     4921 tctcaatggc agttgggctc cagggaccaa tagacctgca gaattgcagg agagtgggga
     4981 ttgctcagct tagcaagatg actggccaag gagcagacca gctgtattta aaacccagca
     5041 ggcatgccca ccacagctcc cagtcattca agatagcaat gaatgtgacc caacagagag
     5101 tcacaattac ttagagcatt atgagactta cctttcaatt tttgaaactc agttgtgtca
     5161 ttcttgagca tgagttttgt tgataaccat taggcccaga caagtcaaga ttggaccaac
     5221 accggtgggg tgtaatgtta gcctgccttc tctagcctta taaagtgggt tctatctctg
     5281 cccaactcct gccttccatc ctgttgctga aactggagga tggccctggc tcatgggaag
     5341 tttggtgcct ttggggtgcc tttccactgt ttgattggat cacagactgc ttccagttta
     5401 tggttggtaa aagaaaagtc actgtgatgt ttaaggtggg caaagtgggc ctggggctta
     5461 aggcggagcg actccactgg gttgtttccc tcctctggca cctctgaaca caaagcctcc
     5521 ctctgcttac tgttgcgccc gccttgcctg ctttctgttc cctgtgatgc ccattggagt
     5581 gtatttgggg gatggggtta tccgctttgt aactgcctta ttgaagtaag tgcccttcca
     5641 tccctggcct ccgactattt gttttcctgc caaacttggg ggggatgggt catttgtatt
     5701 ttgattttgt gcctgtggct ctgtactgtt gaaggtctca gttctctgga ctctccttgg
     5761 catgcatgtg actcctgttg cagtgtcacg caggtgagat ggcctgactc aataaacaat
     5821 ctaaatgagc aagagacta
//
