LOCUS       NM_001081962            1079 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus sin3 associated polypeptide (Sap25), mRNA.
ACCESSION   NM_001081962
VERSION     NM_001081962.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1079)
  AUTHORS   Shiio,Y., Rose,D.W., Aur,R., Donohoe,S., Aebersold,R. and
            Eisenman,R.N.
  TITLE     Identification and characterization of SAP25, a novel component of
            the mSin3 corepressor complex
  JOURNAL   Mol Cell Biol 26 (4), 1386-1397 (2006)
   PUBMED   16449650
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AM275337.1, CB058897.1 and BX517344.1.
            
            [WARNING] On Jan 30, 2025 this sequence was replaced by
            NM_001081962.3.
            
            On Dec 12, 2009 this sequence version replaced NM_001081962.1.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus to one that is  supported by available conservation
            data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AM275337.1, AK164339.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-176               AM275337.1         1-176
            177-344             CB058897.1         155-322
            345-1062            AM275337.1         344-1061
            1063-1079           BX517344.1         433-449
FEATURES             Location/Qualifiers
     source          1..1079
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 76.59 cM"
     gene            1..1079
                     /gene="Sap25"
                     /note="sin3 associated polypeptide"
                     /db_xref="GeneID:751865"
                     /db_xref="MGI:MGI:3802945"
     exon            1..344
                     /gene="Sap25"
                     /inference="alignment:Splign:2.1.0"
     CDS             164..949
                     /gene="Sap25"
                     /note="mSin3A-binding protein; 25 kDa Sin3-associated
                     polypeptide; sin3 corepressor complex subunit SAP25;
                     sin3A-binding protein, SAP25"
                     /codon_start=1
                     /product="histone deacetylase complex subunit SAP25"
                     /protein_id="NP_001075431.2"
                     /db_xref="CCDS:CCDS39336.2"
                     /db_xref="GeneID:751865"
                     /db_xref="MGI:MGI:3802945"
                     /translation="MGILLVLRLTQVSIRKGGEWGSLPFPSHSSQPQALSPSEPGRKQ
                     LPPSRHLATEPTAEAPVRLSPRVTSQVTPSRMSPLPLRDPSHQANAGPRLVEPSCGPG
                     VSLSNRTLCHPSWPMYDNWGRSPTTSERPEEEQVVSKDTGVPVRNYEDVFLLDPLLPC
                     GQRVPLILTKPPQQAMDSRKLLLPPPIMSPSVHPSSSQACSSTWLSEAEMIALAGLLQ
                     MSQGEQTPNCVASSLPSTSCPDPVSVSEDPGPSGDQSCSGTDT"
     exon            345..448
                     /gene="Sap25"
                     /inference="alignment:Splign:2.1.0"
     exon            449..587
                     /gene="Sap25"
                     /inference="alignment:Splign:2.1.0"
     exon            588..685
                     /gene="Sap25"
                     /inference="alignment:Splign:2.1.0"
     exon            686..1065
                     /gene="Sap25"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1043..1048
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sap25"
                     /note="hexamer: AATAAA"
     polyA_site      1065
                     /gene="Sap25"
                     /note="major polyA site"
ORIGIN      
        1 cctccccacc ggcactggtc acggagaggc cttgagctct ggagaggaaa ccatgaagga
       61 gcaagaaacg cctgtgcagg acaggtgagg gcttggtggg ggccactagg aggcgttgtg
      121 ggcgctttcc aaaactgaaa atctacgaga tcgggactgg gaaatgggta tattgttggt
      181 cctgcgacta actcaggtca gcattaggaa gggaggtgag tggggaagcc tgcccttccc
      241 ttcacacagc tcacagcccc aggccctcag cccatctgag ccaggaagaa agcagctgcc
      301 gccttccagg cacctggcta ctgagccgac tgcagaagcc ccagtacgtc tttctccccg
      361 ggtgacctcc caggtcaccc cctcaaggat gtctccactg ccacttcggg atcccagcca
      421 ccaggctaat gcaggacctc ggctggtgga gcccagctgt gggccagggg tatctttgtc
      481 taacaggaca ctgtgccatc cttcctggcc gatgtatgat aactggggca ggagcccaac
      541 cacctcagaa cgcccagagg aagagcaggt ggtgtctaag gatacagggg tcccggtgag
      601 aaactatgaa gatgtctttc tcttggatcc tctgctacca tgtgggcagc gtgttcccct
      661 aatcctgacc aagccccctc agcaggcaat ggactccagg aagctgctgc tcccaccgcc
      721 catcatgtcg ccctctgtgc atccgtcctc atcccaggcc tgctcctcca cctggctcag
      781 cgaggcagag atgatcgccc ttgctggtct gctgcagatg agccagggag agcagacacc
      841 caactgcgtg gcaagctctc tgccttccac cagctgccca gaccctgtct ctgtctctga
      901 agacccaggt cccagtggtg accagagctg ttctgggact gacacatgaa ccacatagta
      961 ccccaataac cacagtccat agtgtaccct gccccccact cctccacggg tgctttcttc
     1021 tcccccaagc tgttttgttg acaataaatc agagtttgca aaccaaaaaa aaaaaaaaa
//
