LOCUS       NM_029489               3152 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus sterile alpha motif domain containing 7 (Samd7),
            transcript variant 1, mRNA.
ACCESSION   NM_029489 XM_130828
VERSION     NM_029489.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3152)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3152)
  AUTHORS   Kubo,S., Yamamoto,H., Kajimura,N., Omori,Y., Maeda,Y., Chaya,T. and
            Furukawa,T.
  TITLE     Functional analysis of Samd11, a retinal photoreceptor PRC1
            component, in establishing rod photoreceptor identity
  JOURNAL   Sci Rep 11 (1), 4180 (2021)
   PUBMED   33603070
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3152)
  AUTHORS   Omori,Y., Kubo,S., Kon,T., Furuhashi,M., Narita,H., Kominami,T.,
            Ueno,A., Tsutsumi,R., Chaya,T., Yamamoto,H., Suetake,I., Ueno,S.,
            Koseki,H., Nakagawa,A. and Furukawa,T.
  TITLE     Samd7 is a cell type-specific PRC1 component essential for
            establishing retinal rod photoreceptor identity
  JOURNAL   Proc Natl Acad Sci U S A 114 (39), E8264-E8273 (2017)
   PUBMED   28900001
  REMARK    GeneRIF: The current study suggests that Samd7 is a cell
            type-specific PRC1 component epigenetically defining rod
            photoreceptor cell identity.
REFERENCE   4  (bases 1 to 3152)
  AUTHORS   Hlawatsch,J., Karlstetter,M., Aslanidis,A., Luckoff,A., Walczak,Y.,
            Plank,M., Bock,J. and Langmann,T.
  TITLE     Sterile alpha motif containing 7 (samd7) is a novel crx-regulated
            transcriptional repressor in the retina
  JOURNAL   PLoS One 8 (4), e60633 (2013)
   PUBMED   23565263
  REMARK    GeneRIF: Data have identified a novel retinal SAM domain protein,
            Samd7, which could act as a transcriptional repressor involved in
            fine-tuning of Crx-regulated gene expression.
REFERENCE   5  (bases 1 to 3152)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   6  (bases 1 to 3152)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158135.5.
            
            On Oct 5, 2022 this sequence version replaced NM_029489.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and is a protein-coding transcript.
            
            CCDS Note: The coding region has been updated to add an internal
            supported exon and to extend the N-terminus by 92 aa.  The
            resulting CDS is one that is more supported by available
            conservation data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.43373.1,
                                           SRR17784643.563946.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                AC158135.5         74149-74204
            57-179              AC158135.5         78862-78984
            180-304             AC158135.5         80917-81041
            305-383             AC158135.5         82080-82158
            384-994             AC158135.5         83955-84565
            995-1113            AC158135.5         86143-86261
            1114-1224           AC158135.5         89956-90066
            1225-3152           AC158135.5         93064-94991
FEATURES             Location/Qualifiers
     source          1..3152
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 14.27 cM"
     gene            1..3152
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /note="sterile alpha motif domain containing 7"
                     /db_xref="GeneID:75953"
                     /db_xref="MGI:MGI:1923203"
     exon            1..56
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            57..179
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..1419
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /note="SAM domain-containing protein 7"
                     /codon_start=1
                     /product="sterile alpha motif domain-containing protein 7"
                     /protein_id="NP_083765.2"
                     /db_xref="CCDS:CCDS17285.2"
                     /db_xref="GeneID:75953"
                     /db_xref="MGI:MGI:1923203"
                     /translation="MTNPMMSVSSLLTSGQQKVPMVPSPFGPPIVDRDVLSSSIAPTD
                     PSQFCVPSQFGSSGLPNANMPNPLSSHFYSGWGILPPEPIKAVTTRNEMFERHHAARA
                     EMEMYSLYQQRRMERVNPKGLSGLGIPLFYGSSCLGGPTGFQGRSTLPASDVHLHRST
                     FRHLQGNPILLATRPHFTECWGQKYRLRRGAVYQKPPESDTESFKSQAEEKSSSQMPT
                     LSYEEEEYIKDPDIEVDNQQKPRVADGKPTTVPANPHGELHTHQRKPSSLEANAWDDG
                     KGKPSEQVYEGCDGKNGVFRPVSILPLSGTHEQVALRENCSLSDIQKWTVDDVYNFIR
                     SLPGCSDYAQVFKDHAIDGETLPLLTEQHLRGTMGLKLGPALKIQSQVSQHVGNMFCK
                     KLPSLPTHARQAFDQPADTSPLLDMSSWSDGLSIPGPQDLLSPKRTEQDVMRN"
     exon            180..304
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            305..383
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            384..994
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1113
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1224
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..3152
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3131..3136
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3152
                     /gene="Samd7"
                     /gene_synonym="4930597A01Rik"
                     /note="major polyA site"
ORIGIN      
        1 aaagagctgt cagcaagggc atccaccgag cacctgagaa gctgctgcaa cagaagagtt
       61 ccatcggagt caagaaacct gatgacaaac ccaatgatgt ctgtgagctc tttactgaca
      121 tcaggacagc agaaggtccc aatggttccc tcgccatttg ggcctccaat tgtggacaga
      181 gatgtcttgt cttccagtat agctccaact gacccaagcc agttttgtgt tccttcccaa
      241 tttggatcct ccggtctccc aaatgcaaat atgccaaacc cgctatccag tcacttctac
      301 tcaggctggg gcattttacc acctgaaccc ataaaggcag tgaccacaag gaatgagatg
      361 tttgaaagac atcacgctgc cagggcagaa atggaaatgt attctcttta ccagcaacgt
      421 agaatggaaa gagttaatcc caaaggactc tctggcctgg gaataccact cttctatggg
      481 tcaagttgcc tgggtggccc cacgggtttc cagggcagga gcacactgcc ggccagtgat
      541 gtgcatttgc acaggagcac cttcagacac cttcagggaa accctattct gctagcaact
      601 agaccccact ttacagagtg ctggggccag aaataccgac tcaggagagg tgcagtttac
      661 cagaagcctc cagagagtga cactgagagt ttcaaaagtc aagcagaaga aaaaagctca
      721 agccagatgc ccacactttc ctatgaggag gaagagtata tcaaggatcc agacattgag
      781 gtagacaacc agcagaagcc aagggtcgct gatggaaagc caactacagt tcccgccaac
      841 ccccacggag aactccatac acaccagagg aaaccgtctt ccctggaggc aaacgcatgg
      901 gatgatggga agggaaagcc ctctgaacag gtctatgaag gctgtgatgg aaagaatggg
      961 gttttccggc cagtctccat cctgcctctg tcaggaacac atgagcaggt tgcactcaga
     1021 gaaaactgct ctttgtctga tattcagaag tggaccgtgg acgatgtgta taacttcatc
     1081 agaagccttc caggctgctc agactatgcc caggtcttta aggaccatgc gattgatgga
     1141 gaaacactgc cccttctcac agaacagcat cttcgaggca ccatgggact caagttgggg
     1201 ccagcactaa aaattcagtc tcaggtatct cagcatgtgg gaaatatgtt ctgtaaaaaa
     1261 cttccttcac ttcccaccca tgcaaggcaa gcatttgatc agccagcaga cacatcccct
     1321 cttttggaca tgagttcctg gagtgatggt ttgagcattc ctggtcccca ggatctactg
     1381 agtcctaaaa gaactgagca agacgttatg agaaattaaa aacacccaaa gacacagatg
     1441 ttccagatgt caccagcagg gtgtgagacc ttcaactggt ggacaaaaag agcgagacca
     1501 tgctcacaga atgtcttgga agaaggatct cacccaacag gcttcctggt aagccgaagc
     1561 aaaccaagca ccaaggttct gaagaactgc cccgaggaga aaatgcgaat ggggagggga
     1621 atttacagac tacgtttaca agctacaatc cgatgattct gtgaagaaaa ttctgaagaa
     1681 gtggagagca gaaactgaaa gggaacctcc ttctactcac tccttccatc gcccaaccct
     1741 gatggagcag caggtgctga tgggaggagg cagggcaaag ctgatgagag acagcacctt
     1801 atctcctagc cacagcagcg tctagcctgc agtggggcct acaaggggga agttaggatt
     1861 taccggaggg gagggggaaa gttatctgtg tgtaacaagt tggaactagt gagagagagg
     1921 tgatgataaa ggtggctgtg tccaggcttc caacttaaca tttgacagaa tgactccaaa
     1981 gggacacaca cacacacaca cacacacaca cacacacaca cacacactgg caacagtatg
     2041 atcagagagg ggactggctg gcaagcatag gaggtcttat tttgaatggt ctgaattgta
     2101 aaccttgaga atgtgtctca cgtgacactc tcagttcaag taaataaacc ctagcagaaa
     2161 gcctttaaga tagcccaccc attgtcgagg gtgcttgcct ttgtataccc ctcccctaca
     2221 gtgtgctgaa ccaaagaaac acaccttcct aagcacaccc ataaggcccg gcagggatcc
     2281 ctgctgtggc ttctgtccca tttctacgtc agtttccctc tccaagaggc cctgggtgac
     2341 accacgtgac taaccttgac agtggacacc gcagagcttg cctgcctttc aggtatgtga
     2401 aagtcttggt ccacagccta atgccaactc acaagacctt agtccaggct ctctgccaag
     2461 cctccgttca gtccctgacc acagaactgt tgtcgcaaac ttgctgtttc cagtcactgc
     2521 tttttggggt cctttcacag acatggagaa ttgaaacaca tagatttaac ttactgacac
     2581 agagagcaca gtactgactc cccgtttggt ctggaaggtg ggcatccaag cccttcctct
     2641 agagttctca tttagttttg ttttggtaat ttttggtttt tctttcttcc atgacaaggg
     2701 tttggtctca tataaaactt atctatgtca tttatgtgtt catgcaggta ttagtgtggg
     2761 tttagacttt gaaactggaa agagcaaaca gagatttgga tgaattcagt tgtggactgt
     2821 ggccatgtgt ggtgggagtg gaaacgaggg gtcccgggag tgggagggca aagcggtggg
     2881 ggagaatcaa caaaagagtc tctgcttgaa aatctcatca ttaaacctaa tacttagtat
     2941 gttaactttt aaaattaatt gttcaaaagc ctgtcagacc atcaaatata cttgcaaaat
     3001 tttagcttaa gctctttatc gttttgttga gagacagtca aaaagcagaa aatctccaca
     3061 actttcaaat ttttattaat ttttcttaag atgggcatta tgctggtaga taacatgtgt
     3121 caaggtttca attaaaagta actcgaaaaa ta
//
