LOCUS       NM_001037221            7120 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus sterile alpha motif domain containing 4 (Samd4),
            transcript variant 1, mRNA.
ACCESSION   NM_001037221
VERSION     NM_001037221.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7120)
  AUTHORS   Kuc,C.A., Brott,J.T., Thorpe,H.H.A., Smart,A. and Vessey,J.P.
  TITLE     Staufen 1 is expressed by neural precursor cells in the developing
            murine cortex but is dispensable for NPC self-renewal and neuronal
            differentiation in vitro
  JOURNAL   Brain Res 1773, 147700 (2021)
   PUBMED   34678304
REFERENCE   2  (bases 1 to 7120)
  AUTHORS   Wang,W., Lv,R., Zhang,J. and Liu,Y.
  TITLE     circSAMD4A participates in the apoptosis and autophagy of
            dopaminergic neurons via the miR-29c-3p-mediated AMPK/mTOR pathway
            in Parkinson's disease
  JOURNAL   Mol Med Rep 24 (1) (2021)
   PUBMED   34080649
  REMARK    GeneRIF: circSAMD4A participates in the apoptosis and autophagy of
            dopaminergic neurons via the miR29c3pmediated AMPK/mTOR pathway in
            Parkinson's disease.
REFERENCE   3  (bases 1 to 7120)
  AUTHORS   Tan,L., Yu,M., Li,Y., Xue,S., Chen,J., Zhai,Y., Fang,X., Liu,J.,
            Liu,J., Wu,X., Xu,H. and Shen,Q.
  TITLE     Overexpression of Long Non-coding RNA 4933425B07Rik Causes Urinary
            Malformations in Mice
  JOURNAL   Front Cell Dev Biol 9, 594640 (2021)
   PUBMED   33681192
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7120)
  AUTHORS   Amadei,G., Zander,M.A., Yang,G., Dumelie,J.G., Vessey,J.P.,
            Lipshitz,H.D., Smibert,C.A., Kaplan,D.R. and Miller,F.D.
  TITLE     A Smaug2-Based Translational Repression Complex Determines the
            Balance between Precursor Maintenance versus Differentiation during
            Mammalian Neurogenesis
  JOURNAL   J Neurosci 35 (47), 15666-15681 (2015)
   PUBMED   26609159
REFERENCE   5  (bases 1 to 7120)
  AUTHORS   Fairfield,H., Srivastava,A., Ananda,G., Liu,R., Kircher,M.,
            Lakshminarayana,A., Harris,B.S., Karst,S.Y., Dionne,L.A.,
            Kane,C.C., Curtain,M., Berry,M.L., Ward-Bailey,P.F., Greenstein,I.,
            Byers,C., Czechanski,A., Sharp,J., Palmer,K., Gudis,P., Martin,W.,
            Tadenev,A., Bogdanik,L., Pratt,C.H., Chang,B., Schroeder,D.G.,
            Cox,G.A., Cliften,P., Milbrandt,J., Murray,S., Burgess,R.,
            Bergstrom,D.E., Donahue,L.R., Hamamy,H., Masri,A., Santoni,F.A.,
            Makrythanasis,P., Antonarakis,S.E., Shendure,J. and Reinholdt,L.G.
  TITLE     Exome sequencing reveals pathogenic mutations in 91 strains of mice
            with Mendelian disorders
  JOURNAL   Genome Res 25 (7), 948-957 (2015)
   PUBMED   25917818
REFERENCE   6  (bases 1 to 7120)
  AUTHORS   Chen,Z., Holland,W., Shelton,J.M., Ali,A., Zhan,X., Won,S.,
            Tomisato,W., Liu,C., Li,X., Moresco,E.M. and Beutler,B.
  TITLE     Mutation of mouse Samd4 causes leanness, myopathy, uncoupled
            mitochondrial respiration, and dysregulated mTORC1 signaling
  JOURNAL   Proc Natl Acad Sci U S A 111 (20), 7367-7372 (2014)
   PUBMED   24799716
  REMARK    GeneRIF: Samd4 has a role in leanness, myopathy, uncoupled
            mitochondrial respiration, and regulation of mTORC1 signaling
REFERENCE   7  (bases 1 to 7120)
  AUTHORS   Baez,M.V., Luchelli,L., Maschi,D., Habif,M., Pascual,M.,
            Thomas,M.G. and Boccaccio,G.L.
  TITLE     Smaug1 mRNA-silencing foci respond to NMDA and modulate synapse
            formation
  JOURNAL   J Cell Biol 195 (7), 1141-1157 (2011)
   PUBMED   22201125
REFERENCE   8  (bases 1 to 7120)
  AUTHORS   Fairfield,H., Gilbert,G.J., Barter,M., Corrigan,R.R., Curtain,M.,
            Ding,Y., D'Ascenzo,M., Gerhardt,D.J., He,C., Huang,W., Richmond,T.,
            Rowe,L., Probst,F.J., Bergstrom,D.E., Murray,S.A., Bult,C.,
            Richardson,J., Kile,B.T., Gut,I., Hager,J., Sigurdsson,S.,
            Mauceli,E., Di Palma,F., Lindblad-Toh,K., Cunningham,M.L.,
            Cox,T.C., Justice,M.J., Spector,M.S., Lowe,S.W., Albert,T.,
            Donahue,L.R., Jeddeloh,J., Shendure,J. and Reinholdt,L.G.
  TITLE     Mutation discovery in mice by whole exome sequencing
  JOURNAL   Genome Biol 12 (9), R86 (2011)
   PUBMED   21917142
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 7120)
  AUTHORS   Baez,M.V. and Boccaccio,G.L.
  TITLE     Mammalian Smaug is a translational repressor that forms cytoplasmic
            foci similar to stress granules
  JOURNAL   J Biol Chem 280 (52), 43131-43140 (2005)
   PUBMED   16221671
  REMARK    GeneRIF: Smaug 1 has a role in RNA granule formation and
            translation regulation in neurons
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131586.10, AK134243.1 and AC159006.2.
            
            On Jul 31, 2009 this sequence version replaced NM_001037221.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK134243.1, SRR10223971.14260.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-204               AC131586.10        85418-85621         c
            205-383             AC131586.10        84009-84187         c
            384-921             AK134243.1         382-919
            922-922             AC159006.2         75760-75760
            923-3505            AK134243.1         921-3503
            3506-7120           AC159006.2         161587-165201
FEATURES             Location/Qualifiers
     source          1..7120
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 24.41 cM"
     gene            1..7120
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /note="sterile alpha motif domain containing 4"
                     /db_xref="GeneID:74480"
                     /db_xref="MGI:MGI:1921730"
     exon            1..204
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            205..822
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     CDS             627..2762
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein Smaug homolog 1; sterile alpha motif
                     domain-containing protein 4A; smaug 1"
                     /codon_start=1
                     /product="protein Smaug homolog 1 isoform 1"
                     /protein_id="NP_001032298.1"
                     /db_xref="CCDS:CCDS26982.1"
                     /db_xref="GeneID:74480"
                     /db_xref="MGI:MGI:1921730"
                     /translation="MMFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLC
                     LEHSLADCAELHVLEGEANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKAEYM
                     KLLPKILAHSIEHNQHIEESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGS
                     QNRGRSDSVDYGQTHYYHQRQNSDDKLNGWQNSRDSGICISASNWQDKSLGCENGHVP
                     LYSSSSVPATINTIGTGASTILSGQAHHSPLKRSVSLTPPMNVPNQPLGHGWMSHEDL
                     RARGPQCLPSDHAPLSPQSSVASSGSGGSEHLEDQTTARNTFQEEGSGMKDVPAWLKS
                     LRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKSLER
                     DIIEGGSLRTPLQELHQMILTPIKAYSSPSTTPEVRCREPSLMESPSPDCKDSAAAVT
                     SATASASAGASGGLQPPQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDE
                     ENISSYLQLLDKCLVHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNR
                     GFGQSNSLPTASSVGSGMGRRNPRQYQIASRNVPSARLGLLGTSGFVSSNQRHTAANP
                     TIMKQGRQNLWFANPGGSNSMPSRTHSSVQKTRSLPVHTSPQNMLMFQQPEFQLPVTE
                     PDINNRLESLCLSMTEHALGDGVDRTSTI"
     exon            823..1341
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..1605
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1715
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1802
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            1803..2115
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            2116..2201
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            2202..2320
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            2321..2522
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            2523..2649
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            2650..2733
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     exon            2734..7120
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2943
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
     regulatory      7100..7105
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /note="hexamer: AATACA"
     polyA_site      7118
                     /gene="Samd4"
                     /gene_synonym="1700024G08Rik; 1700111L17Rik;
                     4933436G17Rik; Samd4a; Smaug; Smaug1; sunk"
                     /note="major polyA site"
ORIGIN      
        1 tcagtccttc gcgagccgac actggaggca gcagtggcgg cagcgatagc gccccgaacc
       61 cgcagcgctg ccctctccgc gcgccgccag ccccgacggc atggcccgca gcccgcgctc
      121 cgagcgcccc caaccccact gattgctgct acggccccgg acccgcgcgc agggccccga
      181 gccgcaggga tgagctgcgt ggagtagtga ttgccgcttg ggaatgcggg tgtgaagggt
      241 ccgagctgcc gcccagcggg gaggagaccc caggacgccg gaaatcacca tcctgaagct
      301 acgagaaaag gggaaggagc gatcttcatt cagttttgtg ccttgcgagg gatttacatt
      361 tttaatcgct attttttttt tttaaaatat ctccgcgcta ctgtctgtca tcgtctctgg
      421 agaatcaacc agaaccacca gaacgtaact gaaccgatag agagaggaga gcaaggcagg
      481 agcagagtca gtacctgcag cgcccgggca ccggagacct tggaaccaga acgtgtctcg
      541 ggaggccacg gggctgcggc tccgccaaac tttggggcgg gcaggagcgc caaggggctt
      601 cgtagacgga gggcggcccc ctaaccatga tgtttcgcga ccaggtcggg gtgctggcgg
      661 gctggtttaa gggctggaac gagtgcgagc agactgttgc actgctgtcg ctgctcaagc
      721 gcgtaagcca gacccaggcc cgcttccttc agctctgcct ggagcactcg ctggccgact
      781 gcgccgagct gcacgtcctg gaaggagagg ccaacagccc gggaatcatt aaccaatggc
      841 aacaggaatc caaggataaa gtgatttccc ttctgctaac tcacctgcct ttgctgaagc
      901 caggaaacct cgacgcgaaa gcagagtata tgaaactgct gcccaagatc ctggcacact
      961 ctatcgaaca caaccagcac attgaggaga gcaggcagct gctgtcctat gctttgatcc
     1021 acccagccac ttccttggaa gaccgcagcg cactagccat gtggctgaat cacttggagg
     1081 accgcacatc caccagcttt ggtagccaga accgaggccg ctcggactct gtggattatg
     1141 gacagacgca ttactatcac caaagacaga actctgacga taagctcaat ggctggcaga
     1201 actctcggga ttctgggatt tgcatcagtg cctccaactg gcaggacaag agcctgggct
     1261 gtgagaatgg ccatgtgccc ctctactctt cctcgtctgt ccctgccaca atcaacacga
     1321 ttggaaccgg cgcaagcacg attctctcag gccaggcaca ccacagccct ttgaaacgat
     1381 ctgtgtccct taccccaccc atgaatgtgc caaaccagcc tctaggacat ggatggatgt
     1441 ctcatgagga cttacgagct agaggacctc agtgcctccc atccgatcat gcccccctgt
     1501 ctccacaaag cagtgtagcc tcttcaggaa gtggtgggag tgaacactta gaagatcaga
     1561 ccactgctcg taacacattc caagaagaag gtagtggtat gaaagatgtt ccagcttggt
     1621 taaaaagcct ccgcctgcac aagtacgctg cgctcttctc gcagatgact tatgaggaaa
     1681 tgatggccct cactgagtgt caactggagg ctcagaatgt taccaaaggc gcaagacaca
     1741 aaattgtaat cagtattcag aagctcaaag aaagacagaa cctcctgaag tctttggaaa
     1801 gggacatcat cgaagggggc agcctgcgca cccccctcca ggagctacat cagatgatcc
     1861 tgacacccat caaggcctac agctctccca gtaccacccc tgaggtgcgc tgccgggagc
     1921 cctcactgat ggagagccca agccctgact gcaaagacag cgctgcagca gtcaccagcg
     1981 ccacagccag tgcctcagcc ggtgccagcg gtggactgca accaccccag ctgagcagct
     2041 gcgacggaga gctggctgtc gcccctctgc cggaggggga cctcccgggg cagttcaccc
     2101 gagtcatggg gaaagtgtgc acacagctct tggtctccag acccgatgaa gaaaatataa
     2161 gctcctatct acagctctta gacaagtgtc ttgttcatga ggcatttaca gagacacaga
     2221 aaaaaagatt gttgtcatgg aaacagcagg tgcagaagct ctttcggtct ttccctcgga
     2281 aaacccttct agacatatca ggatatcgac agcaaagaaa tcgtggcttt gggcagtcca
     2341 actccctccc aacagccagc tctgtgggca gcggcatggg cagacggaac ccacgacagt
     2401 accagatcgc atctcggaat gtcccttccg cccgccttgg tctcctgggc accagtggat
     2461 ttgtcagctc caaccagcgc cacaccgctg ccaaccccac catcatgaaa caaggaagac
     2521 agaacctctg gtttgccaac cctgggggca gcaacagcat gcccagccgc acccacagct
     2581 ccgtccagaa gacccgctcg ctgcccgtgc atacttcccc acaaaacatg ctgatgttcc
     2641 agcaaccaga atttcagctt cctgtgactg aacctgacat caacaatagg ctggagtcct
     2701 tgtgcctcag tatgacggag catgccctgg gagacggggt tgaccggacc tccacaatct
     2761 agaaactgaa gatgacagtg accgcgctgg ccgtgaaatg gactgctgcg ggcccagtgt
     2821 cagccatctt cagggttgca gagactcttc caagacactt tgcagccttt ttcccctggt
     2881 ccctcgccca ttttgatttt gtgagagcgt aggtcatcct tgtaaacata tcagtagacc
     2941 tggggttggt tatgttgtca tttgtttctg tcaggggatg ggacggtatg cagggtgggg
     3001 aggggactct cgggggaatg tggggctggg agggggtgga gggatgctag tagcttcctg
     3061 gatggaaatg gagtggggaa gagtattgct aggtgagata tgcaagagac acacaggagg
     3121 gaggtagaag ccctgccctg gggagccttc tcagaacccg gcttcacagt caggctgcag
     3181 aagacagcgg acacaagcaa ggagagcaag atggcagcca gcctgtttgt ggctcccctg
     3241 accggatttc cccgaggccc ggcttgaaac aaccacaaga gagggctata tggcaccaag
     3301 ggcaagagga agaaattccc tccagcaaac tttcagataa actttgattt gtgtattgtt
     3361 tacataagaa ttttaaaggg tacataatgt gtagagtgtg gatagaactt ctcttcatac
     3421 tatggttttt tttgtaaaag actgattatt gttatggatt cattctgtct catctatttt
     3481 tataatagca gcagggttgt cttttaaaaa aaaaaaaaaa acggctgcca agctctgctt
     3541 cttgggaagg tgattacagt caagtaggcc tcaagttacc gtcttcgacc atgaggtggg
     3601 aggagtgtgt ggatgggttt gaaggataag gatgtggctg agatgaacag agtactaggt
     3661 gtggacacca ggatgatggc gctgtgtgat cagttctgga tttgctcgta ggctatctag
     3721 agatgataaa ctctgcaacc tctttctggg ctggatttgc atcccacgca agacctgttt
     3781 tttgcttccc accctcccca caggctccat cctaccagcc ccggtctccc tccacagaca
     3841 cacacgtgga taacagtccc tctagagaag gaaagacagg ggttgatggt tttcttttgc
     3901 atgaagcctg acactgaaac atctgtgatg gagactttgc aggagcctag gcctgggagt
     3961 cttatctctt ctcactccat ctctgccaaa ggagaatggc ccagcagtag tgtcacagag
     4021 agaatgcaga gatgcaatag gtccccgtgg tccagctcca ccatgggagg aagaggggac
     4081 aatggaaaca gaagcaggaa aggttaagtt cctgagagaa gtggttgctc tctctatgca
     4141 tgtgagtcag agatttgctg tgttgtggga tggtttatcc aaccacgcac agaaaagaga
     4201 aaaccctcac acgtacatta cacagttcga gattaactgt aacaccgtgt gggaatagat
     4261 ctatttctta agggcaacaa agaatagttc agaatttaat gcaatggagg atatcagagg
     4321 gaatccaaaa gaaattatgt gccacactgg agaattagct gcgtaaatgt gacagtatga
     4381 gtgagtagcc ggaggcatga tctagaacat aatataaggc ctgtctagta aatgggtaag
     4441 acagattcct ctttaaaaaa aaaaaaaaaa gtgacattta aaaccagacc atgcaaatga
     4501 ccttgcctat ggttattttt tttttcaagt taatgaagtg cacacagatt ctaaaggcct
     4561 taataaaaat ccacacaact gtgtttgcct gtcaagatta caggtggaca accgagccga
     4621 gccttggatg ctacaacaga gatttcgaag tccttttaca gtgcagggcc aaggacacct
     4681 taagaaggtt gagcttttag tgatcatgga cgacttggat catcacccca atcagcactt
     4741 tataacaaca ccagaaacaa aagatgcagg acactccttg ggtgacccag tcttgaagat
     4801 gcaaattcac gtgcagaaag aggcagcatg tttaattttt atatgtagat agatagactt
     4861 ttttttttta accaagtgcc attaacattc atccctcgtg tccctttcca agctcagtgt
     4921 tggggaagga gctgggatgg aggatcccat gtcaggcaga acaggttaaa atgtcgaagg
     4981 ccaaagggaa ggccagaggg tctgaggaag tgtttggagg atgctggaaa ggttaacaga
     5041 gaggaacaat aggactcctc atcctgtagg aaagagaagg tgtttaagtc cgctacacgc
     5101 aacgcacgta cccataaggt catgggatat tcagaaacca gtttgtgaac acaatcacac
     5161 gagtgcgaat cttttaagag gaagaagacc atagagtata tttgcaaatc tgaatttcta
     5221 tttattcctt cattgaatat agaagcaatg gttatctgat tattagagat attattttgg
     5281 atatgtcact tattaactcg ctatggctgg tacccatgat aaagtctgtt attagtaaca
     5341 acagaattct ttttttaaaa aaaaaaagaa aaaaagaaaa gcttattttt cattgactgt
     5401 atagatttat ctacttagtt gtggtttgct atgttagtgt ttttattttt attttttaag
     5461 ttgtgttctg atgattttta agaacctccc cccccccacc ttgatttgag tcctgtgttg
     5521 actacaggta tacagctcaa tttaaaaatc ctaaagcaaa gaaattttat ttataaaaaa
     5581 aaattttaaa aagagtcgag cagttgcatg cctgaggctg tgaagtcagg ccttgagcag
     5641 tgagctgcag tgcctttttt tgtatttacc cattgaccac cccgccccaa cacagctgtt
     5701 ttatattaaa tagtaaaggt ttgaaacttt ccgagtaaag tctatttcac tgcataggtt
     5761 ctccccatct ccaccccacc ccacccccgc ccccacccgc accccaggcg ccctgattta
     5821 agcagcatgt ctgcactgtc tgagacacaa tgctggtcta caatatcatg gggtgatgtt
     5881 ttattggtgc ttttttgttc atagtgtttt cttaccagaa aacagtagga agaaacacaa
     5941 actatacaag acacaacacg acgctgctga tggtttgttt tgtgtgttcc ccacccccac
     6001 ctgctttttg agtttcactt tcttattaca caaatccagc aagcaaagta gtggccggtg
     6061 ggtcccgcct gcctgcctgc ctagggctgc tatttgcatc aagcgcccag cctgggttga
     6121 gctgaaggtc tctttctggt acccaggccg ggagccagcc gcagctgggc cccacctccc
     6181 attctcccga tgcgacactg agggaaacca gagtttcttt tgaggtgtcg ctggctgcct
     6241 tttacagagt gggagtcttc tctgggcctt cctttcctct gtgcctagta gctagctagc
     6301 gctggtgcaa ggtttgtaga tctgtgcacc ccagagctgg gatgagggct gagcgaggga
     6361 ggggaggaaa gtggattctg ttgggcgccc ttcctctcta gcctgagtgg ggagaaccca
     6421 gggtgctcag gtgtgcctat cataaacaga acctgcagaa ggataagttg tacacagagc
     6481 tgtgatgata tctgtgttgg ctttgttttt cagtttgttt ttcttttctt tttttacaac
     6541 tcatcagaga tgtttgcaaa gcgacttttt ttttaatcct ttatcttgac ttaaaggtaa
     6601 atatgtatcc ctctgggagg agcaaaaaga aagcaggagt gttagtgatg gcaaacagga
     6661 gacttcctcc cttattaata tataaccctc atgtatttat gcctaacgca agctgacttt
     6721 caaagagctt cctttcgttg catgccctgt gcaggcatct gtattgtaca tgcatgcctt
     6781 ttgtcctggt ttcctgtata aagttagtga acaaagaaat atttttgcct agttcatgtt
     6841 gccaagcaat gcatattttt taaatttgtc atacatggaa agagcatgtt tgttacatgt
     6901 gaaagctcta ctgatgcaga tacactaatg tttgaacatg ctgttctttg caagtgtaca
     6961 gttttcaaat gttgttatca gtgacaacac ccttgtggtc taaacttgct acaatgtatt
     7021 tattattcat ttcctcccac agaaataaga atcatggcta tatttcatat ggttatattg
     7081 agagtgaagg gaaatgatta atacaaggtt ttgtaacact
//
