LOCUS       NM_001355709            2462 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus sterile alpha motif domain containing 11 (Samd11),
            transcript variant 2, mRNA.
ACCESSION   NM_001355709 XM_006538841
VERSION     NM_001355709.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2462)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2462)
  AUTHORS   Kubo,S., Yamamoto,H., Kajimura,N., Omori,Y., Maeda,Y., Chaya,T. and
            Furukawa,T.
  TITLE     Functional analysis of Samd11, a retinal photoreceptor PRC1
            component, in establishing rod photoreceptor identity
  JOURNAL   Sci Rep 11 (1), 4180 (2021)
   PUBMED   33603070
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2462)
  AUTHORS   Inoue,T., Terada,K., Furukawa,A., Koike,C., Tamaki,Y., Araie,M. and
            Furukawa,T.
  TITLE     Cloning and characterization of mr-s, a novel SAM domain protein,
            predominantly expressed in retinal photoreceptor cells
  JOURNAL   BMC Dev Biol 6, 15 (2006)
   PUBMED   16539743
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AEKQ02149702.1, CX768146.1 and AK149268.1.
            
            On Sep 26, 2017 this sequence version replaced XM_006538841.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY458844.1, SRR9219382.169554.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AEKQ02149702.1     2035-2049
            16-755              CX768146.1         1-740
            756-2462            AK149268.1         904-2610
FEATURES             Location/Qualifiers
     source          1..2462
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4"
     gene            1..2462
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /note="sterile alpha motif domain containing 11"
                     /db_xref="GeneID:231004"
                     /db_xref="MGI:MGI:2446220"
     exon            1..50
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            51..142
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..1704
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /note="isoform 2 is encoded by transcript variant 2;
                     sterile alpha motif domain-containing protein 11; SAM
                     domain-containing protein 11; major retinal SAM
                     domain-containing protein"
                     /codon_start=1
                     /product="sterile alpha motif domain-containing protein 11
                     isoform 2"
                     /protein_id="NP_001342638.1"
                     /db_xref="CCDS:CCDS89876.1"
                     /db_xref="GeneID:231004"
                     /db_xref="MGI:MGI:2446220"
                     /translation="MPEHPRHCDFQRGNVEIGLGPGGDLLGKRLSCPCITSHCSSEKK
                     ARSKDPQATSLLPELESTMAPEDHYHQLMSALSEASSFEETQRLYHLGIPSHDLLRVR
                     QEVATATLRGPSGLEVHLPSSTADHRRKQGLVQRREGAVPAAATSFSEREMSQPPPLL
                     SPQNAAHITMSSHLRPPFLGMPTAVCQTPGFSFLPSAQAEMLARQQELLRKQSLARLE
                     MSELLRQKELGSVHRPLLPAPEVALHIPEGPDELQRRGSMLVLKHSSAPLLALPPQGP
                     PGPGPPIPPKESARSRSEKGSLGVQPSQPKETTGAGLWAQEVSEEPSKDSDGEDPETA
                     AAREGTSTPSQVPAGGTRAEGRGLLSGSTLPPPLPLGFPCGAVSPYFHTGTMGGLFTD
                     EETTTLEDVNKWTVDDVCNFVGGLSGCGEYARVFGEQGIDGETLPLLTEEHLLNTMGL
                     KLGPALKIRAQVAKRLGRVFYMASFPVALPLQPPSLQAPELSPGHQPLSPATTTSPYE
                     GTHLPTGQASPKQENGSGTIALLSGAPDPSQLLQ"
     exon            143..229
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            230..364
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            365..527
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            528..643
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            644..722
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            723..1225
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1347
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1458
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     exon            1459..2462
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2232..2237
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /note="hexamer: AATAAA"
     polyA_site      2252
                     /gene="Samd11"
                     /gene_synonym="mr-s"
                     /note="major polyA site"
ORIGIN      
        1 cccaggtcac ttcgtagacg ctctgccaga atccagggct gctgtcacag tgcacgtcga
       61 agccgctgcc tcgttatgcc tgagcatcca agacactgtg acttccagag aggcaacgtg
      121 gagatcggcc ttggacctgg aggcgacctg ttgggcaaga ggctgagctg cccctgcatc
      181 accagtcact gctcttcaga gaagaaggcc agaagcaagg acccccaagc gacttcgctg
      241 cttcccgagc tagagtctac aatggccccc gaggaccact accatcagct tatgtcggcc
      301 ctgagtgagg ccagctcctt tgaggaaact caacgtctct accacttggg tatccccagc
      361 cacgatctgc ttagggtacg ccaggaagta gcaactgcaa cactgagggg tcccagtggc
      421 ttggaagttc acctgccctc gtctacagca gaccatcgac ggaagcaagg cctagttcag
      481 cgccgggaag gggcggttcc agctgctgcc acatctttct ctgaaaggga aatgtcacag
      541 ccaccccctt tgctgtcacc ccagaatgcc gcccacatca caatgagctc ccatctccgg
      601 cctccttttc tggggatgcc cacagctgtg tgtcagaccc caggtttcag cttcctaccc
      661 tccgcccagg ctgagatgtt agctcggcag caggaacttc tacggaagca gagcctggct
      721 cggctggaaa tgtcagagtt gcttaggcag aaagaactgg gcagtgttca ccggccactg
      781 ctaccggcac cagaggtggc cttgcatatc cccgagggtc ccgacgaact gcagcgacgt
      841 ggctccatgc tggttttgaa acacagctca gcaccactac tggccctgcc accccaggga
      901 cccccaggcc caggaccccc tatcccaccc aaggagtctg ctcgaagccg gtccgaaaag
      961 gggagccttg gtgtccagcc cagccaaccc aaggagacga caggggctgg cctctgggct
     1021 caagaagtct ctgaggagcc atccaaggac tcagatggag aggaccccga gacagcagct
     1081 gccagggaag ggacctccac tcccagccaa gtcccagcag gagggaccag agcagaagga
     1141 agggggcttc tatcagggtc cacactgccc cctccactgc ccctgggatt cccttgcggg
     1201 gcagtgagcc cctacttcca cacaggtacc atgggggggc tcttcactga tgaggagacc
     1261 acaacccttg aggatgtcaa caagtggact gtagatgatg tctgcaactt cgtggggggc
     1321 ctttctggct gtggcgagta tgccagggta ttcggagaac aaggaataga cggagagact
     1381 ttgcctctac tgacagaaga gcaccttctg aacaccatgg gactgaagct agggcctgcc
     1441 ctcaagatca gggcacaagt ggccaagcgc ctgggccgtg tcttctacat ggccagcttc
     1501 cctgtggccc tgccgctgca gccaccaagc ctgcaagcac ctgagctcag cccaggacat
     1561 caacctctgt cgccagcaac caccacctcc ccgtatgaag ggacccacct gcccacagga
     1621 caagcctcac ccaagcagga gaatgggtca gggaccatag ctctgctttc aggtgcccca
     1681 gacccttccc agcttctcca atgatccggc aggcaaccgt catactccgt gattcccagt
     1741 caaattgcta acctcactcc gcccccaggg tatttcccct ttttagatgc aaaaatgccg
     1801 agagtatttt taaaaggaaa acataaggct taagaagaaa agcaatgagc tgggcagagg
     1861 tggcgcacgc ctttaatccc agcacttggg aggcagaggc aggcggattt cagagttcgc
     1921 ggccagcctg gtctacaaag tgagttccag gatagccagg gctacacaga gacaccctgt
     1981 ctcgaaaaaa caaacaaaca aacaaacaaa caaaagtaat gggtttatct tctagaggta
     2041 actgcagtgc tctgcagaca aaccaaagac aaagtggaga ggagaggcca tggagccgcc
     2101 ctccccactc tgaactggga caacgtcagg gtcagccttc ggcttccggc agcagaaggc
     2161 tctgcagaaa cagttccctc cctttcaggg tcaaaatggc tcctagtaca cttgttctgc
     2221 tgtgctgtaa caataaaagc ctgtttacgc tctgctgtcc tctcgccgca cagttgctgt
     2281 cgaggcctcc aggaggcagc aggaggcctc agtcctcttc tgagagctga agatcctcca
     2341 gctcatcttg tggtccctga gccagctgcc acagttcgct cagatccact cccgtgtctg
     2401 tgtctccatc tacagagaag gaagaggcca cataaataaa ttctgctata tcatgaaaaa
     2461 gc
//
