LOCUS       NP_035446                130 aa            linear   ROD 01-JUN-2024
DEFINITION  serum amyloid A-4 protein precursor [Mus musculus].
ACCESSION   NP_035446 XP_001002620
VERSION     NP_035446.1
DBSOURCE    REFSEQ: accession NM_011316.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 130)
  AUTHORS   Liu,Y., Liu,J., Liu,A., Yin,H., Burd,I. and Lei,J.
  TITLE     Maternal siRNA silencing of placental SAA2 mitigates preterm birth
            following intrauterine inflammation
  JOURNAL   Front Immunol 13, 902096 (2022)
   PUBMED   36211368
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 130)
  AUTHORS   Alldred,M.J., Lee,S.H., Petkova,E. and Ginsberg,S.D.
  TITLE     Expression profile analysis of vulnerable CA1 pyramidal neurons in
            young-Middle-Aged Ts65Dn mice
  JOURNAL   J Comp Neurol 523 (1), 61-74 (2015)
   PUBMED   25131634
REFERENCE   3  (residues 1 to 130)
  AUTHORS   de Beer,M.C., de Beer,F.C., Gerardot,C.J., Cecil,D.R., Webb,N.R.,
            Goodson,M.L. and Kindy,M.S.
  TITLE     Structure of the mouse Saa4 gene and its linkage to the serum
            amyloid A gene family
  JOURNAL   Genomics 34 (1), 139-142 (1996)
   PUBMED   8661036
REFERENCE   4  (residues 1 to 130)
  AUTHORS   Butler,A. and Whitehead,A.S.
  TITLE     Mapping of the mouse serum amyloid A gene cluster by long-range
            polymerase chain reaction
  JOURNAL   Immunogenetics 44 (6), 468-474 (1996)
   PUBMED   8824159
REFERENCE   5  (residues 1 to 130)
  AUTHORS   Butler,A., Rochelle,J.M., Seldin,M.F. and Whitehead,A.S.
  TITLE     The gene encoding the mouse serum amyloid A protein, apo-SAA5, maps
            to proximal chromosome 7
  JOURNAL   Immunogenetics 42 (2), 153-155 (1995)
   PUBMED   7607707
REFERENCE   6  (residues 1 to 130)
  AUTHORS   de Beer,M.C., Kindy,M.S., Lane,W.S. and de Beer,F.C.
  TITLE     Mouse serum amyloid A protein (SAA5) structure and expression
  JOURNAL   J Biol Chem 269 (6), 4661-4667 (1994)
   PUBMED   8308037
REFERENCE   7  (residues 1 to 130)
  AUTHORS   de Beer,M.C., de Beer,F.C., Beach,C.M., Carreras,I. and Sipe,J.D.
  TITLE     Mouse serum amyloid A protein. Complete amino acid sequence and
            mRNA analysis of a new isoform
  JOURNAL   Biochem J 283 (Pt 3) (Pt 3), 673-678 (1992)
   PUBMED   1590757
REFERENCE   8  (residues 1 to 130)
  AUTHORS   de Beer,M.C., Beach,C.M., Shedlofsky,S.I. and de Beer,F.C.
  TITLE     Identification of a novel serum amyloid A protein in BALB/c mice
  JOURNAL   Biochem J 280 (Pt 1) (Pt 1), 45-49 (1991)
   PUBMED   1741755
REFERENCE   9  (residues 1 to 130)
  AUTHORS   Stearman,R.S., Lowell,C.A., Peltzman,C.G. and Morrow,J.F.
  TITLE     The sequence and structure of a new serum amyloid A gene
  JOURNAL   Nucleic Acids Res 14 (2), 797-809 (1986)
   PUBMED   3003697
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ134068.1 and AC090122.26.
            
            On May 4, 2006 this sequence version replaced XP_001002620.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U02554.1, CJ134068.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..130
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 30.53 cM"
     Protein         1..130
                     /product="serum amyloid A-4 protein precursor"
                     /note="serum amyloid A-4 protein; amyloid A-5 protein"
                     /calculated_mol_wt=13227
     sig_peptide     1..18
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=1879
     mat_peptide     19..130
                     /product="Serum amyloid A-4 protein. /id=PRO_0000031592"
                     /note="propagated from UniProtKB/Swiss-Prot (P31532.2)"
                     /calculated_mol_wt=13227
     Region          21..130
                     /region_name="SAA"
                     /note="Serum amyloid A proteins; smart00197"
                     /db_xref="CDD:214552"
     Region          109..130
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P31532.2)"
     CDS             1..130
                     /gene="Saa4"
                     /gene_synonym="Saa-4; Saa-5"
                     /coded_by="NM_011316.4:178..570"
                     /db_xref="CCDS:CCDS21283.1"
                     /db_xref="GeneID:20211"
                     /db_xref="MGI:MGI:98224"
ORIGIN      
        1 mrlatvivlc slflgvsgdg wysffreavq gtwdlwrayr dnleanyqna dqyfyargny
       61 eaqqrgsggi waakiistsr kyfqgllnry yfgirnhgle tlqatqkaee wgrsgknpnh
      121 frpeglpekf
//
