LOCUS       NM_001410576             578 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus S100 calcium binding protein A5 (S100a5), transcript
            variant 5, mRNA.
ACCESSION   NM_001410576 XM_006501180
VERSION     NM_001410576.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Maddala,R., Gao,J., Mathias,R.T., Lewis,T.R., Arshavsky,V.Y.,
            Levine,A., Backer,J.M., Bresnick,A.R. and Rao,P.V.
  TITLE     Absence of S100A4 in the mouse lens induces an aberrant
            retina-specific differentiation program and cataract
  JOURNAL   Sci Rep 11 (1), 2203 (2021)
   PUBMED   33500475
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  AUTHORS   McClintock,T.S., Adipietro,K., Titlow,W.B., Breheny,P., Walz,A.,
            Mombaerts,P. and Matsunami,H.
  TITLE     In vivo identification of eugenol-responsive and muscone-responsive
            mouse odorant receptors
  JOURNAL   J Neurosci 34 (47), 15669-15678 (2014)
   PUBMED   25411495
REFERENCE   3  (bases 1 to 578)
  AUTHORS   Fischl,A.M., Heron,P.M., Stromberg,A.J. and McClintock,T.S.
  TITLE     Activity-dependent genes in mouse olfactory sensory neurons
  JOURNAL   Chem Senses 39 (5), 439-449 (2014)
   PUBMED   24692514
  REMARK    GeneRIF: S100a5 expression is directly and rapidly increased by
            odor stimulation of mouse olfactory sensory neurons. [S100a5]
REFERENCE   4  (bases 1 to 578)
  AUTHORS   Tadenev,A.L., Kulaga,H.M., May-Simera,H.L., Kelley,M.W.,
            Katsanis,N. and Reed,R.R.
  TITLE     Loss of Bardet-Biedl syndrome protein-8 (BBS8) perturbs olfactory
            function, protein localization, and axon targeting
  JOURNAL   Proc Natl Acad Sci U S A 108 (25), 10320-10325 (2011)
   PUBMED   21646512
REFERENCE   5  (bases 1 to 578)
  AUTHORS   Marenholz,I., Lovering,R.C. and Heizmann,C.W.
  TITLE     An update of the S100 nomenclature
  JOURNAL   Biochim Biophys Acta 1763 (11), 1282-1283 (2006)
   PUBMED   16938360
REFERENCE   6  (bases 1 to 578)
  AUTHORS   Marenholz,I., Heizmann,C.W. and Fritz,G.
  TITLE     S100 proteins in mouse and man: from evolution to function and
            pathology (including an update of the nomenclature)
  JOURNAL   Biochem Biophys Res Commun 322 (4), 1111-1122 (2004)
   PUBMED   15336958
  REMARK    Review article
REFERENCE   7  (bases 1 to 578)
  AUTHORS   Ravasi,T., Hsu,K., Goyette,J., Schroder,K., Yang,Z., Rahimi,F.,
            Miranda,L.P., Alewood,P.F., Hume,D.A. and Geczy,C.
  TITLE     Probing the S100 protein family through genomic and functional
            analysis
  JOURNAL   Genomics 84 (1), 10-22 (2004)
   PUBMED   15203200
REFERENCE   8  (bases 1 to 578)
  AUTHORS   Donato,R.
  TITLE     Functional roles of S100 proteins, calcium-binding proteins of the
            EF-hand type
  JOURNAL   Biochim Biophys Acta 1450 (3), 191-231 (1999)
   PUBMED   10395934
  REMARK    Review article
REFERENCE   9  (bases 1 to 578)
  AUTHORS   Ridinger,K., Ilg,E.C., Niggli,F.K., Heizmann,C.W. and Schafer,B.W.
  TITLE     Clustered organization of S100 genes in human and mouse
  JOURNAL   Biochim Biophys Acta 1448 (2), 254-263 (1998)
   PUBMED   9920416
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160552.13.
            
            On Aug 10, 2022 this sequence version replaced XM_006501180.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784644.1397206.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               AC160552.13        166160-166311
            153-308             AC160552.13        169486-169641
            309-578             AC160552.13        171191-171460
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.27 cM"
     gene            1..578
                     /gene="S100a5"
                     /gene_synonym="S100D9"
                     /note="S100 calcium binding protein A5"
                     /db_xref="GeneID:20199"
                     /db_xref="MGI:MGI:1338915"
     exon            1..152
                     /gene="S100a5"
                     /gene_synonym="S100D9"
                     /inference="alignment:Splign:2.1.0"
     exon            153..308
                     /gene="S100a5"
                     /gene_synonym="S100D9"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..452
                     /gene="S100a5"
                     /gene_synonym="S100D9"
                     /codon_start=1
                     /product="protein S100-A5"
                     /protein_id="NP_001397505.1"
                     /db_xref="GeneID:20199"
                     /db_xref="MGI:MGI:1338915"
                     /translation="METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKTELSL
                     AEKMKESSIDNLMKSLDKNSDQEIDFKEYSVFLTTLCMAYNDFFLEDNK"
     exon            309..578
                     /gene="S100a5"
                     /gene_synonym="S100D9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      558..563
                     /regulatory_class="polyA_signal_sequence"
                     /gene="S100a5"
                     /gene_synonym="S100D9"
                     /note="hexamer: AATAAA"
     polyA_site      578
                     /gene="S100a5"
                     /gene_synonym="S100D9"
                     /note="major polyA site"
ORIGIN      
        1 aggagtcttg aagccagaga agaatggaga ggtggactgg cactcagccc tgacatttat
       61 aggccaggtc ctggcctgct accccatcta gctcattggc ttcaaacact ggatcaatcc
      121 tttcctgtcc atgaagggtt ggatgaagaa ggtccagggt acatatcgtt atggagactc
      181 ctcttgagaa ggcactgacc accatggtca ccactttcca taaatattca gggagagagg
      241 gtagcaagct gaccctgagt aggaaagaac tgaaggagtt gatcaagaca gagctgagtc
      301 ttgcagagaa gatgaaggag agcagcattg ataacttgat gaagagcctg gacaaaaaca
      361 gcgaccagga gattgacttc aaggagtact ctgtgttcct gaccacgctg tgcatggcct
      421 acaatgactt cttcctagag gacaacaaat gaccaggaca ctggcagctc ctgatcctga
      481 cctctgcagc ctctttaact gcccctccta tggcccctgc ccttctcttt ctcccagatg
      541 gatccttcca gcagagaaat aaagccttat ccattaca
//
