LOCUS       NM_011310                717 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus S100 calcium binding protein A3 (S100a3), transcript
            variant 4, mRNA.
ACCESSION   NM_011310
VERSION     NM_011310.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 717)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 717)
  AUTHORS   Goodwin,Z.A. and de Guzman Strong,C.
  TITLE     Recent Positive Selection in Genes of the Mammalian Epidermal
            Differentiation Complex Locus
  JOURNAL   Front Genet 7, 227 (2017)
   PUBMED   28119736
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 717)
  AUTHORS   Naba,A., Clauser,K.R., Mani,D.R., Carr,S.A. and Hynes,R.O.
  TITLE     Quantitative proteomic profiling of the extracellular matrix of
            pancreatic islets during the angiogenic switch and insulinoma
            progression
  JOURNAL   Sci Rep 7, 40495 (2017)
   PUBMED   28071719
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 717)
  AUTHORS   Guan,W., Deng,Q., Yu,X.L., Yuan,Y.S., Gao,J., Li,J.J., Zhou,L.,
            Xia,P., Han,G.Y., Han,W. and Yu,Y.
  TITLE     Blockade of S100A3 activity inhibits murine hair growth
  JOURNAL   Genet Mol Res 14 (4), 13532-13544 (2015)
   PUBMED   26535667
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 717)
  AUTHORS   Marenholz,I., Heizmann,C.W. and Fritz,G.
  TITLE     S100 proteins in mouse and man: from evolution to function and
            pathology (including an update of the nomenclature)
  JOURNAL   Biochem Biophys Res Commun 322 (4), 1111-1122 (2004)
   PUBMED   15336958
  REMARK    Review article
REFERENCE   6  (bases 1 to 717)
  AUTHORS   Ravasi,T., Hsu,K., Goyette,J., Schroder,K., Yang,Z., Rahimi,F.,
            Miranda,L.P., Alewood,P.F., Hume,D.A. and Geczy,C.
  TITLE     Probing the S100 protein family through genomic and functional
            analysis
  JOURNAL   Genomics 84 (1), 10-22 (2004)
   PUBMED   15203200
REFERENCE   7  (bases 1 to 717)
  AUTHORS   Kannan,K., Kaminski,N., Rechavi,G., Jakob-Hirsch,J., Amariglio,N.
            and Givol,D.
  TITLE     DNA microarray analysis of genes involved in p53 mediated
            apoptosis: activation of Apaf-1
  JOURNAL   Oncogene 20 (26), 3449-3455 (2001)
   PUBMED   11423996
REFERENCE   8  (bases 1 to 717)
  AUTHORS   Donato,R.
  TITLE     Functional roles of S100 proteins, calcium-binding proteins of the
            EF-hand type
  JOURNAL   Biochim Biophys Acta 1450 (3), 191-231 (1999)
   PUBMED   10395934
  REMARK    Review article
REFERENCE   9  (bases 1 to 717)
  AUTHORS   Ridinger,K., Ilg,E.C., Niggli,F.K., Heizmann,C.W. and Schafer,B.W.
  TITLE     Clustered organization of S100 genes in human and mouse
  JOURNAL   Biochim Biophys Acta 1448 (2), 254-263 (1998)
   PUBMED   9920416
REFERENCE   10 (bases 1 to 717)
  AUTHORS   Kizawa,K., Tsuchimoto,S., Hashimoto,K. and Uchiwa,H.
  TITLE     Gene expression of mouse S100A3, a cysteine-rich calcium-binding
            protein, in developing hair follicle
  JOURNAL   J Invest Dermatol 111 (5), 879-886 (1998)
   PUBMED   9804353
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160552.13.
            
            On Sep 21, 2017 this sequence version replaced NM_011310.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133717.1, CJ048399.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                AC160552.13        159894-159948
            56-201              AC160552.13        161460-161605
            202-717             AC160552.13        161871-162386
FEATURES             Location/Qualifiers
     source          1..717
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.26 cM"
     gene            1..717
                     /gene="S100a3"
                     /gene_synonym="S100E"
                     /note="S100 calcium binding protein A3"
                     /db_xref="GeneID:20197"
                     /db_xref="MGI:MGI:1338849"
     exon            1..55
                     /gene="S100a3"
                     /gene_synonym="S100E"
                     /inference="alignment:Splign:2.1.0"
     exon            56..201
                     /gene="S100a3"
                     /gene_synonym="S100E"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..366
                     /gene="S100a3"
                     /gene_synonym="S100E"
                     /codon_start=1
                     /product="protein S100-A3"
                     /protein_id="NP_035440.1"
                     /db_xref="CCDS:CCDS17537.1"
                     /db_xref="GeneID:20197"
                     /db_xref="MGI:MGI:1338849"
                     /translation="MTRPLEQAVAAIVCTFQEYAGRCGDKYKICQSELKELLQKELPT
                     WTPSEFRECDYNKFMSVLDTNKDCEVDFGEYVRSLASLCLYCHEYFKECPPEPPCPQ"
     exon            202..717
                     /gene="S100a3"
                     /gene_synonym="S100E"
                     /inference="alignment:Splign:2.1.0"
     regulatory      693..698
                     /regulatory_class="polyA_signal_sequence"
                     /gene="S100a3"
                     /gene_synonym="S100E"
                     /note="hexamer: AATAAA"
     polyA_site      717
                     /gene="S100a3"
                     /gene_synonym="S100E"
                     /note="major polyA site"
ORIGIN      
        1 acaaataggg acacccagtt ggtaggctcc tacagctgaa gcaacagcag cagtgtgagg
       61 atgacccggc ccctggagca ggcagtagct gccatcgtgt gcaccttcca ggagtatgca
      121 gggcgctgtg gggataaata caagatctgc cagtcggagc tcaaggagtt gttgcagaag
      181 gagctgccca cctggacgcc gagtgagttc cgggagtgtg actacaataa attcatgagt
      241 gttctggata ccaacaaaga ctgcgaagtg gactttgggg agtacgtgcg ctcacttgcc
      301 agcctctgtc tctactgcca cgagtacttc aaagagtgcc cccctgagcc tccttgcccc
      361 cagtagcctc tgatccaaag gtgtacgcta tcccagaagg gcagggtctg ctccagtcct
      421 ccatctttgt ccttgaggtg gtcctgggtg tgtagccaca cccttcccac tctctctgtg
      481 gtaccccttt caatctagac ttgccaagtt cttgatgtgc taaccccacc cagctaccca
      541 tgagctttcg aggctttcct agggatgtct agcttgtgag gggtgggaca gtagccagcc
      601 tttgccgctt ctcttcttgg aagggaagaa catctctgct cagccatgtg cacacaactg
      661 ggaccgctgt ggcaggggcc tcctcaactc ccaataaaga aatgtcttct tggctta
//
