LOCUS       NM_001195760             315 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus S100 calcium binding protein A2 (S100a2), mRNA.
ACCESSION   NM_001195760 XM_001478157
VERSION     NM_001195760.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Yang,X., Zheng,F., Yan,P., Liu,X., Chen,X., Du,X., Zhang,Y.,
            Wang,P., Chen,C., Lu,H. and Bai,Y.
  TITLE     S100A2 activation promotes interstitial fibrosis in kidneys by
            FoxO1-mediated epithelial-mesenchymal transition
  JOURNAL   Cell Biol Toxicol 40 (1), 86 (2024)
   PUBMED   39382800
  REMARK    GeneRIF: S100A2 activation promotes interstitial fibrosis in
            kidneys by FoxO1-mediated epithelial-mesenchymal transition.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Li,Y., Gudjonsson,J.E., Woods,T.L., Zhang,T., Johnston,A.,
            Stoll,S.W. and Elder,J.T.
  TITLE     Transgenic expression of S100A2 in hairless mouse skin enhances
            Cxcl13 mRNA in response to solar-simulated radiation
  JOURNAL   Arch Dermatol Res 301 (3), 205-217 (2009)
   PUBMED   18773213
  REMARK    GeneRIF: Survival after UVA irradiation was greater in human
            keratinocytes compared to mouse skin with no S100A2 expression,
            showing a protective role for S100A2. A S100A2-dependent difference
            was observed in the induction of Cxcl13 transcripts in transgenic
            mice.
REFERENCE   3  (bases 1 to 315)
  AUTHORS   Shimamoto,S., Takata,M., Tokuda,M., Oohira,F., Tokumitsu,H. and
            Kobayashi,R.
  TITLE     Interactions of S100A2 and S100A6 with the tetratricopeptide repeat
            proteins, Hsp90/Hsp70-organizing protein and kinesin light chain
  JOURNAL   J Biol Chem 283 (42), 28246-28258 (2008)
   PUBMED   18669640
  REMARK    GeneRIF: S100A2 and S100A6 interact with another TPR protein Tom70
            and regulate the Tom70-ligand interaction in vitro
REFERENCE   4  (bases 1 to 315)
  AUTHORS   Marenholz,I., Lovering,R.C. and Heizmann,C.W.
  TITLE     An update of the S100 nomenclature
  JOURNAL   Biochim Biophys Acta 1763 (11), 1282-1283 (2006)
   PUBMED   16938360
REFERENCE   5  (bases 1 to 315)
  AUTHORS   Marenholz,I., Heizmann,C.W. and Fritz,G.
  TITLE     S100 proteins in mouse and man: from evolution to function and
            pathology (including an update of the nomenclature)
  JOURNAL   Biochem Biophys Res Commun 322 (4), 1111-1122 (2004)
   PUBMED   15336958
  REMARK    Review article
COMMENT     PREDICTED REFSEQ: This record has not been reviewed and the
            function is unknown. The reference sequence was derived from
            AC160552.13.
            
            On Sep 25, 2010 this sequence version replaced XM_001478157.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               AC160552.13        149927-150034
            109-315             AC160552.13        150982-151188
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3"
     gene            1..315
                     /gene="S100a2"
                     /gene_synonym="CaN19; EG628324; S100L"
                     /note="S100 calcium binding protein A2"
                     /db_xref="GeneID:628324"
                     /db_xref="MGI:MGI:3510999"
     CDS             1..315
                     /gene="S100a2"
                     /gene_synonym="CaN19; EG628324; S100L"
                     /codon_start=1
                     /product="uncharacterized protein LOC628324"
                     /protein_id="NP_001182689.1"
                     /db_xref="CCDS:CCDS57224.1"
                     /db_xref="GeneID:628324"
                     /db_xref="MGI:MGI:3510999"
                     /translation="MVYTFHKYASQEDERLKHNKGEIKELLRKELLSYVGDNVDDEKV
                     KKEMNNLDKDSDQQVDFRMYALVLVDSAIWFNNFLEGSPALHYLPWISWLKQLSIFLS
                     LY"
     exon            1..108
                     /gene="S100a2"
                     /gene_synonym="CaN19; EG628324; S100L"
                     /inference="alignment:Splign:2.1.0"
     exon            109..315
                     /gene="S100a2"
                     /gene_synonym="CaN19; EG628324; S100L"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggtctata ccttccacaa gtacgccagt caagaggacg agaggctcaa acacaacaaa
       61 ggggagataa aggagctttt gcgtaaggag ctgctgagct atgtggggga taacgtagat
      121 gatgagaagg tgaagaagga aatgaacaac ctcgataagg acagtgacca gcaggtggac
      181 ttccggatgt atgccctggt tctggtggat tctgctatct ggtttaataa cttccttgag
      241 gggtccccag cgctccacta cctgccgtgg atctcttggt tgaaacaact ctctatcttt
      301 ttaagtttgt attaa
//
