LOCUS       NM_009107               2151 bp    mRNA    linear   ROD 05-MAR-2023
DEFINITION  Mus musculus retinoid X receptor gamma (Rxrg), transcript variant
            1, mRNA.
ACCESSION   NM_009107
VERSION     NM_009107.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno
            L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M and Kessaris N.
  TITLE     MTG8 interacts with LHX6 to specify cortical interneuron subtype
            identity
  JOURNAL   Nat Commun 13 (1), 5217 (2022)
   PUBMED   36064547
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2151)
  AUTHORS   Yang L, Du B, Zhang S and Wang M.
  TITLE     RXRgamma attenuates cerebral ischemia-reperfusion induced
            ferroptosis in neurons in mice through transcriptionally promoting
            the expression of GPX4
  JOURNAL   Metab Brain Dis 37 (5), 1351-1363 (2022)
   PUBMED   35486208
  REMARK    GeneRIF: RXRgamma attenuates cerebral ischemia-reperfusion induced
            ferroptosis in neurons in mice through transcriptionally promoting
            the expression of GPX4.
REFERENCE   3  (bases 1 to 2151)
  AUTHORS   Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y,
            Zhou W, Rubenstein JL, Yang Z and Zhang Z.
  TITLE     Dlx1/2-dependent expression of Meis2 promotes neuronal fate
            determination in the mammalian striatum
  JOURNAL   Development 149 (4) (2022)
   PUBMED   35156680
REFERENCE   4  (bases 1 to 2151)
  AUTHORS   Shibata M, Pattabiraman K, Lorente-Galdos B, Andrijevic D, Kim SK,
            Kaur N, Muchnik SK, Xing X, Santpere G, Sousa AMM and Sestan N.
  TITLE     Regulation of prefrontal patterning and connectivity by retinoic
            acid
  JOURNAL   Nature 598 (7881), 483-488 (2021)
   PUBMED   34599305
REFERENCE   5  (bases 1 to 2151)
  AUTHORS   La Manno G, Siletti K, Furlan A, Gyllborg D, Vinsland E, Mossi
            Albiach A, Mattsson Langseth C, Khven I, Lederer AR, Dratva LM,
            Johnsson A, Nilsson M, Lonnerberg P and Linnarsson S.
  TITLE     Molecular architecture of the developing mouse brain
  JOURNAL   Nature 596 (7870), 92-96 (2021)
   PUBMED   34321664
REFERENCE   6  (bases 1 to 2151)
  AUTHORS   Bach I, Rhodes SJ, Pearse RV 2nd, Heinzel T, Gloss B, Scully KM,
            Sawchenko PE and Rosenfeld MG.
  TITLE     P-Lim, a LIM homeodomain factor, is expressed during pituitary
            organ and cell commitment and synergizes with Pit-1
  JOURNAL   Proc Natl Acad Sci U S A 92 (7), 2720-2724 (1995)
   PUBMED   7708713
REFERENCE   7  (bases 1 to 2151)
  AUTHORS   Hoopes CW, Taketo M, Ozato K, Liu Q, Howard TA, Linney E and Seldin
            MF.
  TITLE     Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors
            RXR alpha, RXR beta, and RXR gamma
  JOURNAL   Genomics 14 (3), 611-617 (1992)
   PUBMED   1358808
REFERENCE   8  (bases 1 to 2151)
  AUTHORS   Oakey RJ, Watson ML and Seldin MF.
  TITLE     Construction of a physical map on mouse and human chromosome 1:
            comparison of 13 Mb of mouse and 11 Mb of human DNA
  JOURNAL   Hum Mol Genet 1 (8), 613-620 (1992)
   PUBMED   1301170
REFERENCE   9  (bases 1 to 2151)
  AUTHORS   Mangelsdorf DJ, Borgmeyer U, Heyman RA, Zhou JY, Ong ES, Oro AE,
            Kakizuka A and Evans RM.
  TITLE     Characterization of three RXR genes that mediate the action of
            9-cis retinoic acid
  JOURNAL   Genes Dev 6 (3), 329-344 (1992)
   PUBMED   1312497
REFERENCE   10 (bases 1 to 2151)
  AUTHORS   Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T,
            Chen JY, Staub A, Garnier JM, Mader S et al.
  TITLE     Purification, cloning, and RXR identity of the HeLa cell factor
            with which RAR or TR heterodimerizes to bind target sequences
            efficiently
  JOURNAL   Cell 68 (2), 377-395 (1992)
   PUBMED   1310259
  REMARK    Erratum:[Cell. 1992 Nov 27;71(5):887. PMID: 1330328]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ442702.1, BM947610.1 and BC058401.1.
            
            [WARNING] On May 2, 2023 this sequence was replaced by NM_009107.4.
            
            On Apr 30, 2009 this sequence version replaced NM_009107.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058401.1, SRR1660815.224473.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-274               BQ442702.1         1-274
            275-860             BM947610.1         1-586
            861-2151            BC058401.1         843-2133
FEATURES             Location/Qualifiers
     source          1..2151
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 74.99 cM"
     gene            1..2151
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /note="retinoid X receptor gamma"
                     /db_xref="GeneID:20183"
                     /db_xref="MGI:MGI:98216"
     exon            1..439
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     CDS             391..1782
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     retinoic acid receptor RXR-gamma; nuclear receptor
                     subfamily 2 group B member 3"
                     /codon_start=1
                     /product="retinoic acid receptor RXR-gamma isoform 1"
                     /protein_id="NP_033133.1"
                     /db_xref="CCDS:CCDS15459.1"
                     /db_xref="GeneID:20183"
                     /db_xref="MGI:MGI:98216"
                     /translation="MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPS
                     YTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNV
                     VNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCK
                     GFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRE
                     RAESEAECASSSHEDMPVERILEAELAVEPKTESYGDMNVENSTNDPVTNICHAADKQ
                     LFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVH
                     RSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVET
                     LREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDS
                     FLMEMLETPLQIT"
     exon            440..687
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     exon            688..832
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     exon            833..1012
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1173
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1303
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1436
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..1528
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1634
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..2132
                     /gene="Rxrg"
                     /gene_synonym="Nr2b3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggcgcagtg gtggcggcgg cggcggcggc ggcagcagta gcaacagcag cagcgacggc
       61 ggcggcaaga ggcaaggaga ggtagcagcg gcggcagcat tatgcgtgat tactgacagg
      121 caccagctgc tgcggccgcc acagcctctc aacactatgt ggactctcgg atctagaggc
      181 agattcctga ctaatcccag agggctggcc cagcctgcgc tctcccggct gctagcaagc
      241 gatggccact cttgttagcc caagttgacg gaagcccggc tgtgcctggg agccgagaga
      301 gagagagaga gagagagaga gagagagaga gagagagaga gaggctgtac tcttcagaag
      361 cgcagcagag gaatgaactg agcagccaac atgtatggaa attattccca cttcatgaag
      421 tttcccaccg gctttggtgg ctcccctggt cacactggct cgacgtccat gagcccttca
      481 gtagccttgc ccacggggaa gccaatggac agccacccca gctacacaga caccccagtg
      541 agtgcccctc ggacgctgag tgctgtggga acccccctca atgctcttgg ctctccgtat
      601 agagtcatca cttctgccat gggtccaccc tcaggagcac tggcagctcc tccaggaatc
      661 aacttggtgg ctccacccag ctcccagcta aatgtggtca acagtgtcag cagctctgag
      721 gacatcaagc ccttaccagg tctgcctggg attggaaata tgaactaccc atccaccagc
      781 cctgggtctc tggtgaaaca catctgtgcc atctgtgggg acagatcctc agggaagcac
      841 tacggtgtgt acagctgtga aggttgcaaa ggcttcttca aaaggaccat caggaaagat
      901 ctcatctaca cctgtcggga taacaaagat tgtctcatcg acaagcgcca gcgcaaccgc
      961 tgccagtact gtcgctacca gaagtgcctg gtcatgggca tgaagcggga agctgtgcaa
     1021 gaagaaaggc agaggagccg agagcgagca gagagtgagg cagaatgtgc cagtagtagc
     1081 cacgaagaca tgcccgtgga gaggattcta gaagccgaac ttgctgtgga accaaagaca
     1141 gaatcctacg gtgacatgaa cgtggagaac tcaacaaatg accctgttac caacatatgc
     1201 catgctgcag ataagcaact tttcaccctc gttgagtggg ccaaacgcat cccccacttc
     1261 tcagatctca ccttggagga ccaggtcatt ctactccggg cagggtggaa tgaactgctc
     1321 attgcctcct tctcccaccg ctcggtttcc gtccaggatg gcatcctgct ggccacgggc
     1381 ctccacgtgc acaggagcag cgctcacagc gcgggagtcg gctccatctt cgacagagtc
     1441 cttacagagt tggtgtccaa gatgaaagac atgcagatgg ataagtcaga gctggggtgc
     1501 ctacgggcca tcgtgctgtt taacccagat gccaagggtt tatccaaccc ctctgaggtg
     1561 gagactcttc gagagaaggt ttatgccacc ctggaggcct ataccaagca gaagtatccg
     1621 gaacagccag gcaggtttgc caagcttctg ctgcgtctcc ctgctctgcg ctccatcggc
     1681 ttgaaatgcc tggaacacct cttcttcttc aagctcattg gagacactcc catcgacagc
     1741 ttcctcatgg agatgttgga gaccccactg cagatcacct gaacctcctc agctgcagct
     1801 tccccaccca gggtgaccct gggcgggtgt gtgtgtgtgg ccctaccctg cacactctcc
     1861 cccatcttcc actctggcct cccttcctgt ccccaaaatg tgatgcttgt aataaagaca
     1921 acctttctac acatgagact tttctaggtg gagttttgta cggctgttaa aggtggccct
     1981 tctttgctat ttaaggggct gaggtctttc cggcagttct tgggaagagt ggccaagcct
     2041 ctgtacatat aattggttta aattattttt tcacttgcca tggaaagcaa acaaatggaa
     2101 aagaaaataa taaatatgat attggcactg ctaaaaaaaa aaaaaaaaaa a
//
