LOCUS       NM_016924               2104 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RWD domain containing 2B (Rwdd2b), mRNA.
ACCESSION   NM_016924 XM_001004156
VERSION     NM_016924.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2104)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   3  (bases 1 to 2104)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
REFERENCE   4  (bases 1 to 2104)
  AUTHORS   Orti,R., Rachidi,M., Vialard,F., Toyama,K., Lopes,C., Taudien,S.,
            Rosenthal,A., Yaspo,M.L., Sinet,P.M. and Delabar,J.M.
  TITLE     Characterization of a novel gene, C21orf6, mapping to a critical
            region of chromosome 21q22.1 involved in the monosomy 21 phenotype
            and of its murine ortholog, orf5
  JOURNAL   Genomics 64 (2), 203-210 (2000)
   PUBMED   10729227
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BY094296.1 and
            AK084966.1.
            
            On Dec 12, 2006 this sequence version replaced NM_016924.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK084966.1, BC002143.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                BY094296.1         1-26
            27-2104             AK084966.1         2-2079
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 49.53 cM"
     gene            1..2104
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /note="RWD domain containing 2B"
                     /db_xref="GeneID:53858"
                     /db_xref="MGI:MGI:1858215"
     exon            1..156
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /inference="alignment:Splign:2.1.0"
     exon            157..377
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..1043
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /codon_start=1
                     /product="RWD domain-containing protein 2B"
                     /protein_id="NP_058620.2"
                     /db_xref="CCDS:CCDS37383.1"
                     /db_xref="GeneID:53858"
                     /db_xref="MGI:MGI:1858215"
                     /translation="MVEMEQAEAQLSELDLLASMFPSENELIVNDQLALAELKDCIEK
                     RTMEGRSSQVYFTINVSLDLSEAAVVTFSLSCILPFKYPTVLPEITVRSVSLSRSQQT
                     QLNTDLIAYLQKNCLGDVCILNATEWVKEHAFDYVNIEALPSPARQSTAQPEDLAFTR
                     LWIYSHHIYNKCKRRNILEWAKELSLTGFSMPGKPGVVCVEGPQSACEEFWSRLRKLN
                     WKRILIRHREDIPLDGTAGGMEGQRKFPILEEKAFSVHGARGNHMDFGQLYQFLNARG
                     CGDVFQMFFGVEGQ"
     exon            378..445
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /inference="alignment:Splign:2.1.0"
     exon            446..808
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /inference="alignment:Splign:2.1.0"
     exon            809..2104
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2012..2017
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /note="hexamer: AATGAA"
     polyA_site      2028
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /note="major polyA site"
     regulatory      2090..2095
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
                     /note="hexamer: TATAAA"
     polyA_site      2101
                     /gene="Rwdd2b"
                     /gene_synonym="ORF5"
ORIGIN      
        1 gtcctcacgc gcaggcgccg gcccgcaaag cgctcgctgg cttcccgcaa gaagggttca
       61 aagatcgcgc cgttcccttt ctctctctgg ggtgagacct gagctgcgag cgcgtccggc
      121 cccggggtgt cgccagtgcg ggagccccag ctctggacgt ctgtctcagc atggttgaga
      181 tggagcaggc tgaggcccag ctctccgagt tggacctcct ggccagtatg ttccccagtg
      241 agaatgagct catagtgaat gaccagctgg cattggcgga gctgaaagat tgtattgaga
      301 agaggacaat ggaggggcga tcatcgcaag tgtactttac gatcaatgtg agcctggacc
      361 tctctgaggc agcagtggtg acgttttctt tgtcttgcat tcttcccttt aaatatccta
      421 cagtcctgcc cgaaattaca gtgagatcag tatcgctgag tagatcccag cagactcagc
      481 tgaacacaga tctgatagca tacctgcaga agaactgtct tggagatgtc tgtatcctga
      541 atgccacaga gtgggttaaa gagcatgcct ttgactatgt caacatagaa gctttgccct
      601 cccccgccag gcaaagcaca gcccagccag aggatctcgc tttcacgagg ctctggatct
      661 acagccatca catctacaac aagtgcaaaa gaagaaacat cctagagtgg gcaaaggaat
      721 tgtccctgac tgggtttagc atgcctggga aacctggtgt tgtttgtgtg gaaggcccgc
      781 aaagtgcttg tgaggaattc tggtcaagac tcagaaaact aaactggaag aggattttaa
      841 ttcgtcatcg agaagacatt cctcttgacg gtacagccgg cggaatggaa ggacagcgga
      901 aatttcccat tcttgaagaa aaggccttca gtgtccacgg agccagagga aaccacatgg
      961 actttggcca gctgtatcag ttcttaaatg ccaggggatg tggggatgtt ttccagatgt
     1021 tctttggtgt agaaggacag tgactgagca gaggggaagt cagacctgtt ggctcactgt
     1081 tcctctgttg atcatttctt cctgtttttc cttgaaattc aatttcagct ccattctagg
     1141 atgtactagg gttggggtca caagaagaaa attaatatgg ctgaaatgta tcagttaaaa
     1201 cttgccatgc ctgagagaaa aactgggttt cgacttgtaa gctttaaatt actaagtgag
     1261 aagggtggag aaatgactca gaagttaaga gcatatgctg ctagtgccaa ggacctaagt
     1321 tcagttccca gcacccctgg cagggagctc ataactacct atatgtcttt acttcagggc
     1381 atttgatgta ctctgtcctc caagggtgca tgcatgaaca taaacatgta aatatatttg
     1441 gggtatcaga tcccctggag ctggagttac aggaggttgt gaggtacccg gtgtgggtgc
     1501 tgggagccaa acttgggtcc tctgcaagag cagtgcaccc ttttaacctc tgagccatct
     1561 ctacagcttg gtggaaattt cttgacgtga gctggatctg aaggcacatg cttataatcc
     1621 cagcacttgg gaagtagagg caggaggatg ggaagttgaa ggccagctgg gctacacgag
     1681 gctctgtctc atgaaacttg aaagacaaat tatatgtgaa ggtaattttg atggttcgac
     1741 ttgctaggga tttcccacac tcttctgcct tcactaggaa cctggaaaag ctgcctgttc
     1801 accctcctgg cctctcttgc agctgcattg ggctgtaggt tacagtgcag gatttctggg
     1861 gatgaatttg cctctcttct ctttctgcca tggcccctga agtgatggca agagaaaggg
     1921 ccaagctatc tcagagatgt cattgtacaa gacaccttgc cacatgcgga cccaatgtta
     1981 atcccagcct gtctccagac ctttgaaata aaatgaaatt ttaaacaatc tgtgcttgtt
     2041 atcagtagtc agaagtttga aactaccctg tcttttaaag tacaaacagt ataaagcctt
     2101 cctc
//
