LOCUS       NM_009822               7256 bp    mRNA    linear   ROD 12-AUG-2024
DEFINITION  Mus musculus RUNX1 translocation partner 1 (Runx1t1), transcript
            variant 3, mRNA.
ACCESSION   NM_009822 XM_975417 XM_975502
VERSION     NM_009822.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7256)
  AUTHORS   Murray,J.E., Valli,E., Milazzo,G., Mayoh,C., Gifford,A.J.,
            Fletcher,J.I., Xue,C., Jayatilleke,N., Salehzadeh,F., Gamble,L.D.,
            Rouaen,J.R.C., Carter,D.R., Forgham,H., Sekyere,E.O., Keating,J.,
            Eden,G., Allan,S., Alfred,S., Kusuma,F.K., Clark,A., Webber,H.,
            Russell,A.J., de Weck,A., Kile,B.T., Santulli,M., De Rosa,P.,
            Fleuren,E.D.G., Gao,W., Wilkinson-White,L., Low,J.K.K.,
            Mackay,J.P., Marshall,G.M., Hilton,D.J., Giorgi,F.M., Koster,J.,
            Perini,G., Haber,M. and Norris,M.D.
  TITLE     The transcriptional co-repressor Runx1t1 is essential for
            MYCN-driven neuroblastoma tumorigenesis
  JOURNAL   Nat Commun 15 (1), 5585 (2024)
   PUBMED   38992040
  REMARK    GeneRIF: The transcriptional co-repressor Runx1t1 is essential for
            MYCN-driven neuroblastoma tumorigenesis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7256)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7256)
  AUTHORS   Asgarian,Z., Oliveira,M.G., Stryjewska,A., Maragkos,I., Rubin,A.N.,
            Magno,L., Pachnis,V., Ghorbani,M., Hiebert,S.W., Denaxa,M. and
            Kessaris,N.
  TITLE     MTG8 interacts with LHX6 to specify cortical interneuron subtype
            identity
  JOURNAL   Nat Commun 13 (1), 5217 (2022)
   PUBMED   36064547
  REMARK    GeneRIF: MTG8 interacts with LHX6 to specify cortical interneuron
            subtype identity.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7256)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7256)
  AUTHORS   Mayer,C., Hafemeister,C., Bandler,R.C., Machold,R., Batista
            Brito,R., Jaglin,X., Allaway,K., Butler,A., Fishell,G. and
            Satija,R.
  TITLE     Developmental diversification of cortical inhibitory interneurons
  JOURNAL   Nature 555 (7697), 457-462 (2018)
   PUBMED   29513653
REFERENCE   6  (bases 1 to 7256)
  AUTHORS   Neidhardt,L., Gasca,S., Wertz,K., Obermayr,F., Worpenberg,S.,
            Lehrach,H. and Herrmann,B.G.
  TITLE     Large-scale screen for genes controlling mammalian embryogenesis,
            using high-throughput gene expression analysis in mouse embryos
  JOURNAL   Mech Dev 98 (1-2), 77-94 (2000)
   PUBMED   11044609
REFERENCE   7  (bases 1 to 7256)
  AUTHORS   Buchholz,F., Refaeli,Y., Trumpp,A. and Bishop,J.M.
  TITLE     Inducible chromosomal translocation of AML1 and ETO genes through
            Cre/loxP-mediated recombination in the mouse
  JOURNAL   EMBO Rep 1 (2), 133-139 (2000)
   PUBMED   11265752
REFERENCE   8  (bases 1 to 7256)
  AUTHORS   Davis,J.N., Williams,B.J., Herron,J.T., Galiano,F.J. and Meyers,S.
  TITLE     ETO-2, a new member of the ETO-family of nuclear proteins
  JOURNAL   Oncogene 18 (6), 1375-1383 (1999)
   PUBMED   10022820
REFERENCE   9  (bases 1 to 7256)
  AUTHORS   Niwa-Kawakita,M., Miyoshi,H., Gotoh,O., Matsushima,Y.,
            Nishimura,M., Shisa,H. and Ohki,M.
  TITLE     Cloning and gene mapping of the mouse homologue of the CBFA2T1 gene
            associated with human acute myeloid leukemia
  JOURNAL   Genomics 29 (3), 755-759 (1995)
   PUBMED   8575770
REFERENCE   10 (bases 1 to 7256)
  AUTHORS   Erickson,P.F., Robinson,M., Owens,G. and Drabkin,H.A.
  TITLE     The ETO portion of acute myeloid leukemia t(8;21) fusion transcript
            encodes a highly evolutionarily conserved, putative transcription
            factor
  JOURNAL   Cancer Res 54 (7), 1782-1786 (1994)
   PUBMED   8137293
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844572.8, BY779334.1, BC139200.1, AK032132.1 and AL807804.16.
            
            On Oct 29, 2013 this sequence version replaced NM_009822.2.
            
            Transcript Variant: This variant (3) differs in the 5' UTR and the
            5' coding region and initiates translation at an alternate start
            codon, compared to variant 1. It encodes isoform 3, which has a
            shorter and distinct N-terminus, compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The extent of this transcript is
            supported by transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D32007.1, BC139200.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AL844572.8         17216-17218
            4-274               BY779334.1         1-271
            275-2617            BC139200.1         1-2343
            2618-2880           AK032132.1         2553-2815
            2881-7256           AL807804.16        47053-51428
FEATURES             Location/Qualifiers
     source          1..7256
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 5.88 cM"
     gene            1..7256
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /note="RUNX1 translocation partner 1"
                     /db_xref="GeneID:12395"
                     /db_xref="MGI:MGI:104793"
     exon            1..360
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     CDS             354..2087
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /note="isoform 3 is encoded by transcript variant 3; acute
                     myelogenous leukemia 1 translocation 1 protein; protein
                     CBFA2T1; CBFA2T1 identified gene homolog; runt-related
                     transcription factor 1; translocated to, 1 (cyclin
                     D-related)"
                     /codon_start=1
                     /product="protein CBFA2T1 isoform 3"
                     /protein_id="NP_033952.1"
                     /db_xref="CCDS:CCDS17978.1"
                     /db_xref="GeneID:12395"
                     /db_xref="MGI:MGI:104793"
                     /translation="MPDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPPTTQGAPRTSSF
                     TPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRF
                     LTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKA
                     NLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTP
                     DRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLD
                     DMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLL
                     NCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPV
                     NPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHD
                     MITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYC
                     GSFCQHKDWEKHHHICGQTLQAPQQGDTPAVSSSVTPSSGAGSPMDTPPAATPRSTTP
                     GTPSTIETTPR"
     exon            361..498
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            499..740
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            741..830
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            831..1012
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1263
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1349
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1551
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1620
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1811
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     exon            1812..7256
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3126..3131
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /note="hexamer: ATTAAA"
     polyA_site      3148
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
     regulatory      7235..7240
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /note="hexamer: AATAAA"
     polyA_site      7256
                     /gene="Runx1t1"
                     /gene_synonym="Cbfa2t1h; ETO; MTG8"
                     /note="major polyA site"
ORIGIN      
        1 ctggaactgg ggcaggagga agagtggaga aagggagaca ggagttgtga tactttgtac
       61 acacgtccct gtcattgttc tgcctgaaga gacagggctg ggttcaaggc cacatgtgtt
      121 cctgtcatcc tgcacatttc tgctccaagt gcaatccgga gtgtcagctc tccatctgtc
      181 tctgcctggc aggcgcacgc gcccagcacc ctgcctcggg ccatgccgcc ccagcccctc
      241 tgatggccct cctctccacc gccccgcaca ttccagaaca ggaggcatga gcccgcatcg
      301 cgctccctct taacacagag ttgctttcag tgtgttacac gctggattcc gggatgcctg
      361 atcgtaccga gaagcactcc acaatgccag actcacctgt ggatgtgaag acgcagtcta
      421 ggctgactcc cccagcaatg ccacctcctc caaccactca aggagctcca agaaccagct
      481 catttacgcc aacgacatta acgaatggca ccagccattc acccacggcc ttgaatggcg
      541 ctccctcacc gcctaatggc tttagcaacg ggccttcttc ttcctcttcc tcttctctgg
      601 ctaatcagca gctgccccca gcctgtggtg ctaggcaact cagcaagctg aaacgatttc
      661 ttactaccct gcagcagttt ggcaatgaca tttcaccaga gattggagaa agagttcgca
      721 cccttgtact gggactggtg aactctactt tgacaattga agaatttcat tccaaactgc
      781 aagaagctac taacttccca ctgagacctt ttgtcatccc gtttttgaag gccaacctgc
      841 ccctgctcca gcgtgaactc ctccactgcg caaggctagc caaacagaac cctgcccagt
      901 acctcgctca gcacgaacag ctgcttctgg atgccagcac cacctcccct gtcgactcct
      961 cagagctgct tctcgacgtg aacgaaaacg ggaagaggcg aactccagac agaaccaaag
     1021 aaaatggctt tgacagagag cctttgcact cagaacatcc aagcaagcga ccatgcacta
     1081 ttagcccagg ccagcggtac agtccaaata atggcttatc ctaccagcca aatggcctgc
     1141 ctcaccccac cccacctcca cctcagcatt accgattgga tgatatggcc attgcccacc
     1201 actacaggga ctcctatcga caccccagcc acagggacct cagggacaga aatagaccta
     1261 tggggttaca tggcacacgt caagaagaaa tgattgacca cagactaaca gacagagaat
     1321 gggcagaaga gtggaaacat ctcgatcatc tgttaaactg catcatggac atggtggaga
     1381 agacaagacg atccctcact gtactaagac gatgtcagga agcggaccgg gaagaactga
     1441 attactggat acggcggtac agtgatgctg aggacttaaa aaagggtggc agcagtagca
     1501 gcagccactc caggcagcag agtcctgtca atccagaccc agtcgcatta gatgcacatc
     1561 gggaattcct tcacaggcct gcgtctggat acgtgccaga ggagatctgg aagaaagctg
     1621 aggaagctgt gaatgaggtg aagcgacagg caatgacgga gctgcaaaaa gccgtgtctg
     1681 aggcagagag gaaagcccat gacatgatca ccacggagcg agccaagatg gaacgcacgg
     1741 tggctgaagc gaagaggcag gcagcagaag atgctctagc agtcatcaac cagcaggaag
     1801 actccagtga gagttgctgg aactgtggcc ggaaagcaag tgagacgtgc agcggctgta
     1861 acacggcccg atactgtggc tctttttgcc agcataaaga ctgggagaag catcaccaca
     1921 tctgtggaca gaccctgcag gccccacagc agggagacac gcccgctgtc agctcctcag
     1981 tcacacccag cagtggggct gggagcccaa tggacacacc accagcagcc actccgaggt
     2041 ctaccacccc gggaaccccc tctaccatag agacgacgcc tcgctagacc taaactcaga
     2101 ctgtcagagg aaagacacca caaccaacac gaaagcaatt cctcatcctc agatgctcaa
     2161 agtccctttt ctgtttgttt gtttatagat gaactatcta tcttatttca gtacttcggc
     2221 aagagagaac ctaactgtat ctttgaggcg atagtagaac acagaggcca gtaacgggtc
     2281 gtaatgactt actgtggata acaaagatat cttttcttta gagaactgaa aagagaggaa
     2341 agaatataac gtgaaatgct agatttgacc tcctccctgt tatttccaag tagctgggat
     2401 tttaaactag atgacctcat taaccagtgc tttaccaaac agcaaaccaa gagattgcta
     2461 attgctgttg aaagcaaaaa tgctaatatt aaaagtcaca gtgttcttta tatacaataa
     2521 tggaaaaaaa aaaaagaggc aattcctcaa gggcatgagc ggtggataca gaagtagaca
     2581 ttttaacaag aagatgaatg gcgtctgtgg gttgctaact gaactttgaa gacccgctgc
     2641 aaaacgcgca gatgtgcagc agattggaag gagacacaga tggtcctttt tttcctgttt
     2701 ctgaaaaaga aataataata tccaggtcaa cagaatgaaa aatgaaagat gatttccagt
     2761 gcggtgtatg actacagcag caagaaaaaa aaatgccata atacaaaggc tcctttttat
     2821 atatatagtc acacacacac acacacacac acacacacac acacacacac acttaagaga
     2881 ctcagcctgc agttaattag cattctggca gcttccaagt cagccagctg ccctaaataa
     2941 cccttcaaca tttcttcact tttgcaaggt tccacagact aagacattgg gtctattcca
     3001 gctcattcat tttatattga aaactaattt aaaaaaaaat ggtggcttca gctccagccc
     3061 ctttccaaaa tttttcaacc ccaccctgtt tggattttta attaaaatct agtagttctc
     3121 ttggtattaa aacacttctg tcctgtgagg ttttcccaat ggtgtttttc ttgtaaatgt
     3181 gttggacaaa tgtgaagatg cgttgtagtt tacccatatg cccacattta gtctctttat
     3241 tcctagttgg tgagaaacct gtatctttct atgctgcttt tatatctgta tgtattagtg
     3301 atatttctct agtagttaaa aaaaaaaaaa aagaaaaaaa aaactttttt ggttgtcctc
     3361 aagaaaagaa aagaagaaaa gaaaagaaaa gaaaaagcta tcttttggag ctgctaactc
     3421 actctcttat aggatttttt ttcctggaaa ccagcatgct tcatggaatg ctagcacatg
     3481 gatgttttaa gagggatgta cataaatgta ttttgcactg tcacaatgac tccctaggca
     3541 tgctttcttt ttttcaaacc aactttttaa atatgctaga gccatttcac caattttagc
     3601 tgtagcatag agtagtagtg gaatttttct ttcttttatc ctttttttat gaaaagaaat
     3661 tattagggac ttttttaaaa aaaataaaat aagatatcct actttaaaaa aaaaaaggac
     3721 agtgcatgca tattgctgta aggttgttta agtatttcta attttacaaa aaaaaaatga
     3781 aaaaaatcat tagagctcca aatgctgagg tgtagacgaa cagctttaac cctgctgagt
     3841 gccaggtaat acagtgttct tacaaaaggg aaatcagcca aagactgatc tgagggacca
     3901 aaatcggaac tttgaaaagc accagtggta ctttccaaat gatcagcagg ttgaacatgt
     3961 tcagtgtgaa tccattaacc cttcgttgtc cagggtccag accagaacta ctggttagtt
     4021 ttgaaacaca ttagcccagg atgtggttgt gtgctttaag agtcggcagt gctgcaggct
     4081 gtgtagacaa ccaaagttga caaggctggg aagacacttc tccacatacc catacaccag
     4141 gcatttcttt acaaattgag tacaatccat tagcttgcgg gagggggagg ggagcgggta
     4201 atgtagccct tggatacagt tttaagtggt tgtatttaag ttatctgcat agaggcaatc
     4261 ctcctgggtt tgctttatgt ctcgaaaatc taagattttt cttaaaccat ttcccccata
     4321 ttttcatata ccagtcggtt ttgattttgt tccggtggtg ttgtgttctt tctttctttt
     4381 tttttttttt ttttttttct tttttctttt caatggcctt ttaatttagg aagttctgat
     4441 gagcaaataa atgcatctat atctatctgc atgttggaag tccatctgcc agcacacctg
     4501 ctaaaggcaa cgagaagcac ataagcaggc tctgaatggg ttctatctta ccatggtgct
     4561 cccagaatcc tttgacctca ttctgctttc tagtctgctt gtgacactgg acagtccttt
     4621 cttagagcta ttctatgttc taggctacga agggttaaat aatcccaaaa atgaggtatg
     4681 tcataccctc acgtctcgat ctcaagaagc tgtgatgtac gtggaacagc actgttattc
     4741 tgaacactag tgtgtaaagt aaggattagt acagtccgtc tcattacttt ttaattcagg
     4801 gcaccctgag tgaaaaccaa tacaaaaaaa aaaaaaatcc ctaactctga gctctatctc
     4861 taattcctct tcctccttcc cctcttcctc ctcctcttcc tctcctcctg ttttgctaca
     4921 ttctcctcag tggcaaaaag tttcactcta cctctgacag catgtatatt gcaccagtag
     4981 ctaacaaaaa ctggtctagt caaaccaaat gggcacaaaa gaaccaggat accaaaagtc
     5041 atacagctgc aaaccatatc acttcttggt aacaatgcag acctcataaa cctaaaaaag
     5101 agaaagaaaa gaaaactttt gttactttcc ttttttgctt gtcacttata tacaggctat
     5161 gtgagagtat tgatttgtag gtattacaca ttaaaaaaaa agttatcttc attggataga
     5221 attgaatggt ggtcgctgat aggaataggg cgtcctctat ctcttatctc tgtctctttt
     5281 ctctttctct ttctctgtca tgagactgtg tgtgacaggg ccacctgtct tttttatttt
     5341 tatttttctg aacttttttt tttttaatgt gtaggtgcat gtcttgggga tttaaaaatt
     5401 tcaaggctgg tttacttatg caaagcatgc ctatgtctgg aatacttagg gaaagaaagc
     5461 gactccatgt tgtccgaatt cctcaaggga cagaaaaaaa aaaattggag actgttgaaa
     5521 tgcagatttg aagtaatttt attttaatta ttttgggttc tgcgacatta ttgtgaaaaa
     5581 ttaaagttgt tgtgcaatac ttaattcaga cacgtgccac aagttaacgg tagactaaca
     5641 ctggggggcg ggggctaggc atcacgcttt tgtctgcata ctcttgagct tttaagtcta
     5701 ctatgtccga actgtggttt cttgtttatc cttttttttt tttttcctta gttggactgt
     5761 aatgtatggt ctgtcaacct gtgaatcttt aaagtatgat tcaggtattg ttgtactctt
     5821 tactgtgtaa taaaaatgct taaaaaaaag tctgtattct gtctccctta tctttactgt
     5881 gtgccaaggc taccactcag ggaccttagc cttgaagggc agttcttcat ggagcatgcc
     5941 cggagtctag tcaactccag agtatgtctc taacatgtgt tagttcatcc ctgagtgatg
     6001 agggagaatg atagagcaca gaggacattc ctgaggtcat tgtagtcaaa tgtagaagga
     6061 ctctcaaagt cctccataag aaaggagagc atagtctagg ggtctccttc tctagaaagg
     6121 tccatttacc atcttctaaa gctctgacat gcagaaggtt gctcccatgc atagctgcag
     6181 gatgtacaca ctaagacact ccatccgtct tggatcctca ctgcctttaa tcagatgttg
     6241 ccagcatgtt cacacttggt tttgtacact tgtaatacac agtatggtgt gtccaacttg
     6301 tttctaagac ccatgtccat ctaacacaca taagtatata ttttttcatg cactagctat
     6361 aaagtagctt agaatttgga gaacctattg gtctacccta ggaacacagt caattttcga
     6421 gtactttaca caacatattt tttttaaagg aatgtataca ctacattctg gtaaaacttc
     6481 ttgtttgctt gaaagattcc cactatggcc taaaaactag tttaaaggga taaagggaaa
     6541 tgcaaggcct gaatctgaag agacagagac atcagagatg ctgatgagtg ggagggtaat
     6601 cttcagcttc ctttgtatgc taactaggcc cctatacctg tcctgagacc tggcttcttc
     6661 aaggatattg agaaatgcag cctattttac agagtgagga aaggagggag ggagagagag
     6721 agacagagat agagacagag agagtttaaa agcctagata gtgcatatct tatccctaca
     6781 aaataaacag gctgaatatt taattaagta gttaattttt ttccccactc aaaagcctgc
     6841 ccagcctttc cttatttgta cagatacatt ttctttttct tttcaaaatg gaacagacca
     6901 gaaaccagaa gacatggagg ctagaacgga gtcgccttga agtagcccct ttataagctg
     6961 tccttgaaaa acagctctgt gacatatttg tatgactgga tatgctggac aaatgcgtaa
     7021 tgagtttagt taagatgaag aatgtgagca aaatcagcag cttctgggtg gtgagcacca
     7081 ttttttaaaa gaatgttatt gatgtatttg ataatataaa aatgatgttt gccatgaaag
     7141 aacactaagt tatttcccca aaatggaagg ggaagaaatg atcaaagagg tgcttttctg
     7201 tatgggtgtt tatatcttta ttccaaggtg aatgaataaa gttgtacttg cctaaa
//
