LOCUS       NM_001347311            3822 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus RUN domain containing 3B (Rundc3b), transcript variant
            1, mRNA.
ACCESSION   NM_001347311 XM_006503577
VERSION     NM_001347311.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3822)
  AUTHORS   Skarnes,W.C., Rosen,B., West,A.P., Koutsourakis,M., Bushell,W.,
            Iyer,V., Mujica,A.O., Thomas,M., Harrow,J., Cox,T., Jackson,D.,
            Severin,J., Biggs,P., Fu,J., Nefedov,M., de Jong,P.J., Stewart,A.F.
            and Bradley,A.
  TITLE     A conditional knockout resource for the genome-wide study of mouse
            gene function
  JOURNAL   Nature 474 (7351), 337-342 (2011)
   PUBMED   21677750
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121955.2, AC107733.14 and AC152165.2.
            
            On Nov 19, 2016 this sequence version replaced XM_006503577.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363658.1650489.1,
                                           ERR3765653.1923974.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-465               AC121955.2         90984-91448         c
            466-581             AC121955.2         72366-72481         c
            582-715             AC107733.14        190944-191077       c
            716-801             AC107733.14        181414-181499       c
            802-891             AC107733.14        171331-171420       c
            892-972             AC107733.14        160155-160235       c
            973-1141            AC152165.2         15596-15764
            1142-1299           AC152165.2         23354-23511
            1300-1446           AC152165.2         31963-32109
            1447-1568           AC152165.2         49465-49586
            1569-3822           AC152165.2         51781-54034
FEATURES             Location/Qualifiers
     source          1..3822
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 3.43 cM"
     gene            1..3822
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /note="RUN domain containing 3B"
                     /db_xref="GeneID:242819"
                     /db_xref="MGI:MGI:2685286"
     exon            1..465
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     CDS             341..1714
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /note="isoform 1 is encoded by transcript variant 1; RUN
                     domain-containing protein 3B"
                     /codon_start=1
                     /product="RUN domain-containing protein 3B isoform 1"
                     /protein_id="NP_001334240.1"
                     /db_xref="CCDS:CCDS84841.1"
                     /db_xref="GeneID:242819"
                     /db_xref="MGI:MGI:2685286"
                     /translation="MASRSLGGLSGSRGGGGGGGGKKSLSARNAAVERRNLITVCRFS
                     VKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVAC
                     RKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDG
                     AIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSD
                     EEELRTFGSSDSESSTPENVGPPLILDENTWFNKCKRVRQKYQLTLEQKGYLEELLRL
                     RENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQEL
                     TAHLTKQWPSPGALDVNAVALDTLLYRKHNKQWYDKSYQSLDQLSAEVSLSQASLDPS
                     HSQEGDGKQDSLNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTTELT
                     SPGLTPS"
     exon            466..581
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            582..715
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            716..801
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            802..891
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            892..972
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1141
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1299
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1446
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            1447..1568
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..3822
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3801..3806
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /note="hexamer: ATTAAA"
     polyA_site      3822
                     /gene="Rundc3b"
                     /gene_synonym="Gm440"
                     /note="major polyA site"
ORIGIN      
        1 cggagcccgc cctcccgccc gcccgcccgc gcgcgcttct ctcgtggacg gcggcggcgg
       61 cgcgcgcgcg cgcgagcgag ggtggaggtg gctcgtgcgt gcgtgtgagt gagcgcgtgt
      121 gtatgtgtga gagagcgtgt gtgagtgtgt gtgcacgcgc gcgtggagcc tgggtaccgg
      181 tgcccgactg actgccttcc acaccctgcc tactccgcgc ctccttcctc gcctctctcc
      241 cgcccggcgg gctgccatcg ttgagagaag gccgggggac acaggtgtgc gaggcttgcg
      301 ggaccgctgg agacaaaggg ggcgcggagg tgagcccgcc atggcctccc ggagcctggg
      361 gggcctgagc gggagccgcg gcggcggcgg cggcggcggc ggcaagaaga gcctgagcgc
      421 ccgcaacgct gcggtggaga ggaggaacct gatcaccgtg tgcagatttt ctgtgaagac
      481 cctgattgat cggtcttgct ttgaaacaat tgatgattca tctcctgaat ttaataactt
      541 tgcagctgtt ctggaacaaa ttctaagtca ccggctaaaa ggtcaagtaa catggtttgg
      601 ctatgaaagc ccacgtagct tctgggacta tatcagagtg gcttgccgga aagtttcaca
      661 aaactgtatc tgtagtattg aaaatatgga aaatgtcagc tcctccagag ctaagggtag
      721 agcctggatc agagtagcac tcatggaaaa acatttgtct gaatacatct ctacagcttt
      781 gagagacttc aaaacaacca ggaggtttta tgaagatgga gccattgtct tgggtgaaga
      841 agcaaatatg cttgctggca tgctgcttgg actcaatgct attgacttca gcttctgcct
      901 aaagggagaa ggattagatg gcaccttccc tgctgtgata gactatacac catatttgaa
      961 gtttgaacaa agttctgaca gcatcagcag tgacgaggag gaactcagga cgtttgggag
     1021 cagtgacagt gagagcagca ccccagagaa tgtgggaccg cctctcatcc tagacgagaa
     1081 cacctggttc aacaagtgca agagagtaag gcagaaatac cagcttaccc tggagcagaa
     1141 gggttatctt gaagaactct tgcggcttcg tgagaaccaa ctttctgaat ctgtctctca
     1201 gaataaaatc ctacttcaga ggatcgaaga ttctgatctg gcccacaaat tggagaaaga
     1261 acagttagaa tatatcattg tggagcttca agatcagctg actgtactaa agaataatga
     1321 tttaagatca agacaagagt taactgccca cctcaccaag cagtggccct ccccaggagc
     1381 tctggatgtc aatgctgttg ccttggatac cttgctttac cgaaaacaca ataaacagtg
     1441 gtatgataaa agttaccaaa gccttgacca gttatcagca gaagttagcc tttctcaggc
     1501 ctcattggat cccagccact cacaagaagg agatggaaag caagactcat tgaatttcat
     1561 tggtgaaggt aaagaagata ccccctcact tcttggcctc tgtgggtccc tgacatcagt
     1621 ggcaagttac aagtccctaa caagcctaaa atccaacgac tgccttgcaa gccccaccac
     1681 ggagctaacc agcccaggcc tgactccatc ctgaaagact acgtaaaaac ccaaagtttc
     1741 tgcattgtaa atatcctgtt tacataagtt tggctgctgg gagattttga aattttatat
     1801 tctggtacat gcgtaacatt ttgttgtttg gagattttag tccagcccat gtaaatttct
     1861 gagggaaaag catagtagtc ccctattttt ctttttaaaa tattacattt gtcactgagg
     1921 atgtttaaag ttgattaggc tttaaaaatc tttcaaagag tgtctgaatt cattataaat
     1981 tgtacatagt tgttattcag ctgaattttt atatttgttt aaatgcgtct tggtgtccag
     2041 agaccaggtc caggttttac tccagagact taagcttagc agtttctttc gctcctttat
     2101 ttggtggtta aatttgcaca aaaggcaact aattccatga agtacttcct gcactctgat
     2161 gtctgtgtac catgctgtaa ggggaagtct ccagccacaa ctacacagtg gctcgttaag
     2221 ctttcctttt accagttggt accaactttt agcatttcat aaagtttgta gaattgtgcc
     2281 tttttaggcg gttgctgact taatttgtca ggtatggagg aaaagcatct tttcccaggt
     2341 atgcctaaga cattggaaac atttcaaact tcagaactaa tgttggcaag gggttactaa
     2401 cctcagaagt ttccagttta atgaatgact tgataatgat ttttaaagag ctgcagagta
     2461 accaggatgt ctgactgtgg atatacattg gagctacaat gctattttcc ctgtgtgcaa
     2521 caatgactta catactgggt gtttcatagc cattaccact atgccatgat ttctcatttt
     2581 tcaaattgat cttagtgttt aaaaaaaaac aaaactatac ttctgtagga aaacaggttt
     2641 tttaaaaaga gctgtgtttc aatttttttt tttacaattt ttaaaacagc tacatgtgtc
     2701 cctaaaaatt ccaccctatt gaaaataaac acgtatgaag tgtgtattct atagtgagtc
     2761 ctaggaggaa aacaagtgtg ccaaagacat ttcctatact gtttcatgaa ggggccacag
     2821 tgctcactct tgtctgttga tttttatatt taaacttagc agctgtgaca agtaggaagt
     2881 gcatccctcc taaagcttcc tggggagtgc tgaactcaca ggttcactcc ttctatccaa
     2941 agtgtagggg tgggaggttc tgggaagtgc ttggagcgca gtctcatggt gtggaatcaa
     3001 tcaatagtaa catgaccagt gtcacatgtg aggcagtgca gacactaatc tctggggcaa
     3061 aggaggcctg caagctcatg acagacattg catcgggtga ctcagaacaa actgagcaat
     3121 ttcttcctga ggctgatgca ttaaaacaga gcacctccat cttctctgat ctgtgtgcac
     3181 catattaagt gtacagtggc caaagccacg tttaagtagt gtcaggaata gcaaataaag
     3241 acagcaggcc tgcagcaggc tgcatgagga cttagatggt catgagaaca ttgggaattt
     3301 aggctggccg tgggcgcacc tctactttcc taagaaagtc aaagtgttta ctgctttatc
     3361 accacggcct gctctcacct gtcatttatg atttttcaga tataaaacct tggtaagatc
     3421 ttttcataca tttttataaa gtagaaggga atacaagatt ccccagttgg tacacttttt
     3481 cagatctgtc cgatagaagc actagtttgt gacatatccc tgctgcgaac tgcggactga
     3541 gacatgacac ctgaggatca tggctttccc tccattattg gagctcttga tataaagttc
     3601 atctgctact gtggaaccca agtttctgca gttggtttcg agctacaggc agtttgtaac
     3661 gcttgcatga gtgaacagtg tctcagtctt taattttcag tggtactgtt tatttttcag
     3721 aactccacaa agaatgctgg ctatgtctat ctttccatct gtattttgtt gcctcgatgt
     3781 actatatttg ttgcatgtat attaaagatt tttttaacca ta
//
