LOCUS       NM_023386               1573 bp    mRNA    linear   ROD 27-FEB-2024
DEFINITION  Mus musculus receptor transporter protein 4 (Rtp4), mRNA.
ACCESSION   NM_023386
VERSION     NM_023386.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Liu,H., Zhou,R., Li,S., Dong,J., Fang,Y., Luo,Y., Su,H., Lai,B.,
            Liang,L., Zhang,D., Zhang,Y., Shyy,J.Y., Zhou,B., Yuan,Z. and
            Wang,Y.
  TITLE     Epigenetic repression of Cend1 by lysine-specific demethylase 1 is
            essential for murine heart development
  JOURNAL   iScience 27 (1), 108722 (2023)
   PUBMED   38226173
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  AUTHORS   Kaur,R., Tada,T. and Landau,N.R.
  TITLE     Restriction of SARS-CoV-2 replication by receptor transporter
            protein 4 (RTP4)
  JOURNAL   mBio 14 (4), e0109023 (2023)
   PUBMED   37382452
  REMARK    GeneRIF: Restriction of SARS-CoV-2 replication by receptor
            transporter protein 4 (RTP4).
REFERENCE   3  (bases 1 to 1573)
  AUTHORS   Fujita,W., Uchida,H., Kawanishi,M., Kuroiwa,Y., Abe,M. and
            Sakimura,K.
  TITLE     Receptor Transporter Protein 4 (RTP4) in the Hypothalamus Is
            Involved in the Development of Antinociceptive Tolerance to
            Morphine
  JOURNAL   Biomolecules 12 (10), 1471 (2022)
   PUBMED   36291680
  REMARK    GeneRIF: Receptor Transporter Protein 4 (RTP4) in the Hypothalamus
            Is Involved in the Development of Antinociceptive Tolerance to
            Morphine.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1573)
  AUTHORS   He,X., Ashbrook,A.W., Du,Y., Wu,J., Hoffmann,H.H., Zhang,C.,
            Xia,L., Peng,Y.C., Tumas,K.C., Singh,B.K., Qi,C.F., Myers,T.G.,
            Long,C.A., Liu,C., Wang,R., Rice,C.M. and Su,X.Z.
  TITLE     RTP4 inhibits IFN-I response and enhances experimental cerebral
            malaria and neuropathology
  JOURNAL   Proc Natl Acad Sci U S A 117 (32), 19465-19474 (2020)
   PUBMED   32709745
  REMARK    GeneRIF: RTP4 inhibits IFN-I response and enhances experimental
            cerebral malaria and neuropathology.
REFERENCE   5  (bases 1 to 1573)
  AUTHORS   Fujita,W., Yokote,M., Gomes,I., Gupta,A., Ueda,H. and Devi,L.A.
  TITLE     Regulation of an Opioid Receptor Chaperone Protein, RTP4, by
            Morphine
  JOURNAL   Mol Pharmacol 95 (1), 11-19 (2019)
   PUBMED   30348895
  REMARK    GeneRIF: Selective MOPr-mediated increase in RTP4 expression.
REFERENCE   6  (bases 1 to 1573)
  AUTHORS   Decaillot,F.M., Rozenfeld,R., Gupta,A. and Devi,L.A.
  TITLE     Cell surface targeting of mu-delta opioid receptor heterodimers by
            RTP4
  JOURNAL   Proc Natl Acad Sci U S A 105 (41), 16045-16050 (2008)
   PUBMED   18836069
  REMARK    GeneRIF: RTP4, a Golgi chaperone, is a regulator of the levels of
            heterodimers at the cell surface; association with RTP4 protects
            mu-delta receptors from ubiquitination and degradation
REFERENCE   7  (bases 1 to 1573)
  AUTHORS   Saito,H., Kubota,M., Roberts,R.W., Chi,Q. and Matsunami,H.
  TITLE     RTP family members induce functional expression of mammalian
            odorant receptors
  JOURNAL   Cell 119 (5), 679-691 (2004)
   PUBMED   15550249
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC217053.3.
            
            [WARNING] On Apr 1, 2024 this sequence was replaced by NM_023386.6.
            
            On Sep 3, 2009 this sequence version replaced NM_023386.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024872.1, AK018021.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-231               AC217053.3         112077-112307
            232-1573            AC217053.3         115039-116380
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 14.55 cM"
     gene            1..1573
                     /gene="Rtp4"
                     /gene_synonym="5830458K16Rik; Ifrg28"
                     /note="receptor transporter protein 4"
                     /db_xref="GeneID:67775"
                     /db_xref="MGI:MGI:1915025"
     exon            1..231
                     /gene="Rtp4"
                     /gene_synonym="5830458K16Rik; Ifrg28"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..820
                     /gene="Rtp4"
                     /gene_synonym="5830458K16Rik; Ifrg28"
                     /note="28kD interferon alpha responsive protein; 28 kDa
                     interferon-responsive protein"
                     /codon_start=1
                     /product="receptor-transporting protein 4"
                     /protein_id="NP_075875.3"
                     /db_xref="CCDS:CCDS28079.1"
                     /db_xref="GeneID:67775"
                     /db_xref="MGI:MGI:1915025"
                     /translation="MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGW
                     RQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQ
                     FETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEAC
                     SLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQ
                     GCREPPQREIEPPLFLFLSIAAFALFSLFTR"
     exon            232..1573
                     /gene="Rtp4"
                     /gene_synonym="5830458K16Rik; Ifrg28"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctctcccag atttgaggaa gacagtgagc tgctgagtaa cccggggcct cagcttccac
       61 acctctgaga atgctgttcc ccgatgactt cagtacttgg gagcagacat ttcaagaact
      121 gatgcaggag gagaagcccg gggccaagtg gagcctgcat ttggataaga acattgtacc
      181 agatggtgca gccctgggat ggaggcagca ccagcagaca gtgcttggca ggttccagtg
      241 ttccagatgc tgcagaagtt ggacctctgc tcaggtgatg atcttgtgcc acatgtaccc
      301 ggacactttg aaatcgcagg gccaggcacg catgaggatc tttggtcaga agtgccagaa
      361 gtgttttgga tgtcaatttg agactcccaa gttctccaca gagatcatca aaagaattct
      421 gaataaccta gttaattata ttctgcagag atactatgga cacaggaaga tagcattgac
      481 ctcgaatgca tctttgggtg agaaggtgac tttggatggg ccccacgaca cacgcaattg
      541 tgaggcatgc agtctaaact ctcatggaag atgtgccctt gcacacaaag taaaaccacc
      601 cagatctcca tctccattac caaagagttc ctccccatca aagagctgcc ctcctccgcc
      661 tcagacccgg aatacggatt ttgggaataa aacttttcag gattttggga atagaacttt
      721 tcagggatgc agagagcccc cccaacgtga aatagagcca ccactatttc tgtttttgtc
      781 tattgctgca tttgcccttt ttagtctttt cactagataa taggtttatc gtcttgtttt
      841 aataccttgg tgatcaatga aatagatgtc atttcaatag gacagtgaat tcatatagaa
      901 tcaagtaagg tcgagtatat aaaataaatc tgctttcctg gacatgctct gaaaatagcc
      961 taaaccatgg cccacacata atggacccaa taacagattt gtattgagtt gctgaactgt
     1021 ctgcactagc ttgctcacgt attgttctca agctatgttg attaaataaa tcttgattat
     1081 aactaacagt cacctgtgct atgagataca aagcggcggc cggagtaagg gaatacctgc
     1141 agggcccctg ccaaggtgcc ccctgagaaa tcatgccacg taacagacct ggtgtaaggg
     1201 agtttattag tgagggaagc agggacctag agaagtgggg agcagagcta tgaggacaga
     1261 gaacggggga cagagaagga cagagagagg ggctggccag gaacacgagg gaacagagag
     1321 agaaagagga aggaggaggg gggctgggga gtaggctgcc cctgcaccac ctggctcgaa
     1381 cccagtgggc agcaggtgat gacataagcc taggtccctg ggagaagcct agtggaatct
     1441 tctgttaacc aacaatgagt attattgtaa atttactgtg gcagactggg tgatgctccc
     1501 cccccacaca caccaaaaat gcccttcccc atagcctcta gaatttgtga ataaactcta
     1561 tttgttggaa gaa
//
