LOCUS       NM_013648               1994 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus reticulon 2 (Z-band associated protein) (Rtn2),
            transcript variant B, mRNA.
ACCESSION   NM_013648
VERSION     NM_013648.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Zhou,J., Shi,Q., Ge,Y.Y., He,W., Hu,X., Xia,W. and Yan,R.
  TITLE     Reticulons 1 and 3 are essential for axonal growth and synaptic
            maintenance associated with intellectual development
  JOURNAL   Hum Mol Genet 32 (16), 2587-2599 (2023)
   PUBMED   37228035
REFERENCE   2  (bases 1 to 1994)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1994)
  AUTHORS   Iwai-Takekoshi,L., Balasubramanian,R., Sitko,A., Khan,R.,
            Weinreb,S., Robinson,K. and Mason,C.
  TITLE     Activation of Wnt signaling reduces ipsilaterally projecting
            retinal ganglion cells in pigmented retina
  JOURNAL   Development 145 (21) (2018)
   PUBMED   30254141
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1994)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1994)
  AUTHORS   Ikemoto,T., Hosoya,T., Takata,K., Aoyama,H., Hiramatsu,T., Onoe,H.,
            Suzuki,M. and Endo,M.
  TITLE     Functional role of neuroendocrine-specific protein-like 1 in
            membrane translocation of GLUT4
  JOURNAL   Diabetes 58 (12), 2802-2812 (2009)
   PUBMED   19720795
REFERENCE   6  (bases 1 to 1994)
  AUTHORS   Oertle,T., Klinger,M., Stuermer,C.A. and Schwab,M.E.
  TITLE     A reticular rhapsody: phylogenic evolution and nomenclature of the
            RTN/Nogo gene family
  JOURNAL   FASEB J 17 (10), 1238-1247 (2003)
   PUBMED   12832288
REFERENCE   7  (bases 1 to 1994)
  AUTHORS   Bois,P.R., Southgate,L. and Jeffreys,A.J.
  TITLE     Length of uninterrupted repeats determines instability at the
            unstable mouse expanded simple tandem repeat family MMS10 derived
            from independent SINE B1 elements
  JOURNAL   Mamm Genome 12 (2), 104-111 (2001)
   PUBMED   11210178
REFERENCE   8  (bases 1 to 1994)
  AUTHORS   Geisler,J.G., Palmer,R.J., Stubbs,L.J. and Mucenski,M.L.
  TITLE     Nspl1, a new Z-band-associated protein
  JOURNAL   J Muscle Res Cell Motil 20 (7), 661-668 (1999)
   PUBMED   10672514
REFERENCE   9  (bases 1 to 1994)
  AUTHORS   Geisler,J.G., Stubbs,L.J., Wasserman,W.W. and Mucenski,M.L.
  TITLE     Molecular cloning of a novel mouse gene with predominant muscle and
            neural expression
  JOURNAL   Mamm Genome 9 (4), 274-282 (1998)
   PUBMED   9530622
REFERENCE   10 (bases 1 to 1994)
  AUTHORS   Stubbs,L., Carver,E.A., Shannon,M.E., Kim,J., Geisler,J.,
            Generoso,E.E., Stanford,B.G., Dunn,W.C., Mohrenweiser,H.,
            Zimmermann,W., Watt,S.M. and Ashworth,L.K.
  TITLE     Detailed comparative map of human chromosome 19q and related
            regions of the mouse genome
  JOURNAL   Genomics 35 (3), 499-508 (1996)
   PUBMED   8812484
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AU066588.1, CJ176292.1 and AK144271.1.
            
            On Oct 12, 2012 this sequence version replaced NM_013648.5.
            
            Transcript Variant: This variant (B) represents the longer
            transcript and encodes the longer isoform (B).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK001789.1, BC031370.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AU066588.1         1-33
            34-38               CJ176292.1         1-5
            39-1994             AK144271.1         2-1957
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.54 cM"
     gene            1..1994
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /note="reticulon 2 (Z-band associated protein)"
                     /db_xref="GeneID:20167"
                     /db_xref="MGI:MGI:107612"
     exon            1..242
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            243..287
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            288..758
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            759..1022
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1230
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1369
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1439
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1486
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1545
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1994
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1966..1971
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /note="hexamer: AATAAA"
     polyA_site      1990
                     /gene="Rtn2"
                     /gene_synonym="MMS10-P; Ms10p; Nspl1; NSPLI"
                     /note="major polyA site"
ORIGIN      
        1 agtgcttgct cctctgcggc cccgccctcc cccgcggagt ggagcagagg gcggcggcgg
       61 tggcggcggt ggcggcggcg gctgctaaag cagcccggga ggatggcggc ggcgtcgtcg
      121 acgcggcgga gatgagcgcc cgtggcccca ggcccagggc ggcgcggccg gagtgggcgg
      181 gggtcccgat gcaggcccga ggggggccat ggggcaggtc ctgccggtct tcgcccactg
      241 caaagaagct ccatctacag cctcttctac ccccgattcc acggaaggag ggaatgacga
      301 ctcagatttt cgggagctgc acacagcccg ggaattctca gaggatgaag aggaggagac
      361 cacatcgcag gactggggca cccccaggga gctgaccttt tcctacattg ccttcgacgg
      421 cgtggtgggc tctgggggcc gtagggactc agttgttcgt cgtccccggc cccagggacg
      481 ttcagtctca gaaccacggg acccacccca acagtccggc ctgggtgaca gcttggaaag
      541 catccctagc ctgagccagt ccccagagcc agggcgccgc ggtgaccctg accccgtgcc
      601 tccagctgag cgcccgctgg aggaactgag gctgcggctg gaccagcttg gctgggttgt
      661 ccggagtgcg ggatctgggg aggattcggc caccagcagc tccacccctc tggaaaatga
      721 ggagcctgat ggattggagg ccagcgaggc tggagaagag acgaatctgg aactccgact
      781 tgctcagtct ctacatttgc aacttgaggt cctgactcct caacttagcc ctagctccgg
      841 gaccccccag gcgcatactc catccccaca aagatctcaa gattcgaact ccggtcctga
      901 tgatgagcct ctgctgaatg tggtagaaga gcattggcgg ctgctggagc aggagccaat
      961 cacggcccag tgcctcgata gcacagacca atcagaattc atgttggagc cgctccttct
     1021 agtggcagac ctgttgtact ggaaggacac caggacgtcg ggagcggtct tcacgggcct
     1081 catggcctct ctcctctgcc tcctgcactt tagcatcgtg tccgtggctg cgcacctggc
     1141 cctgttgggt ctctgcgcca ccatctctct cagggtttac cgcaaagtgc tgcaggccgt
     1201 gcaccggggc gacggcacca accctttcca ggcctacctg gacatggacc tgaccctgac
     1261 tcgggagcag acagaacgtt tgtcccagca gatcgcctcc cacgtggtct ccacagccac
     1321 acagctacgg catttcttcc tagtggaaga cctggtggat tctctcaagc tggctcttct
     1381 cttctacatc ttgacctttg tgggagccat cttcaacggc ttgactcttg tcatcctagg
     1441 agtggttgct ttgtttaccg tcccccttct gtacagacaa catcaggccc agattgacca
     1501 gtatgtgggg ttggtgacca atcagttgag ccacatcaaa gctaagatcc gagctaagat
     1561 cccggggacc ggaacccttg ccccaacagc atcagtctcc ggatccaaag ccaaagccga
     1621 atgagagggg tgtctttgcc cgatggacgc ctgcctatac cccagcagcc ctcttccctt
     1681 ccatttcccg tgcatccaca ccctctccca ctcggccgag ccatttccca gtgggaagtg
     1741 cctgagcgac ccggactaca tttcctaaga ggctctgctc taagagtcca ggaaaaggcc
     1801 gcggagcctg ctgggacttg tagttgaata gtcaggacgc tgccctgcac ttccgtgacc
     1861 caccgctgga ggcgccgtga ggggttggtg cctctgaagc caccaacccc tatgctgggg
     1921 ctttgcatgg ggcccaggcg agccttgagc ttggatttac actgtaataa agagtcctgt
     1981 ggaaaattca ctgc
//
