LOCUS       NM_025542               2142 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus replication termination factor 2 (Rtf2), mRNA.
ACCESSION   NM_025542
VERSION     NM_025542.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2142)
  AUTHORS   Conti,B.A., Ruiz,P.D., Broton,C., Blobel,N.J., Kottemann,M.C.,
            Sridhar,S., Lach,F.P., Wiley,T.F., Sasi,N.K., Carroll,T. and
            Smogorzewska,A.
  TITLE     RTF2 controls replication repriming and ribonucleotide excision at
            the replisome
  JOURNAL   Nat Commun 15 (1), 1943 (2024)
   PUBMED   38431617
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK077823.1.
            
            On Apr 5, 2007 this sequence version replaced NM_025542.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077823.1, BC049072.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2142              AK077823.1         2-2143
FEATURES             Location/Qualifiers
     source          1..2142
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 94.86 cM"
     gene            1..2142
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /note="replication termination factor 2"
                     /db_xref="GeneID:66404"
                     /db_xref="MGI:MGI:1913654"
     exon            1..162
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..1017
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /note="likely orthologue of H. sapiens chromosome 20 open
                     reading frame 43 (C20orf43); UPF0549 protein C20orf43
                     homolog; replication termination factor 2
                     domain-containing protein 1; protein RTF2 homolog;
                     replication termination factor 2 domain containing 1"
                     /codon_start=1
                     /product="replication termination factor 2"
                     /protein_id="NP_079818.1"
                     /db_xref="CCDS:CCDS17132.1"
                     /db_xref="GeneID:66404"
                     /db_xref="MGI:MGI:1913654"
                     /translation="MGCDGGTIPKRHELVKGPKKVEKVDKDAELVAQWNYCTLSQEIL
                     RRPIVACELGRLYNKDAVIEFLLDKSAEKALGKAASHIRSIKNVTELRLSDNPAWEGD
                     KGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLRCCGCVFSERALKEIKAEVCHTC
                     GAAFQEEDIIVLNGTKEDVEMLKKRMEERRLRAKLEKKTKKPKTATECASKPGTTQDS
                     AGPSKVKSGKPEEADPDPREKKSTPAPRGAATNGSASGKVGKPPCGALKRSIADSEES
                     ETYKSIFTSHSSAKRSKEESAHWVTHTSYCF"
     exon            163..257
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            258..351
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            352..491
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            492..570
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            571..684
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            685..742
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            743..838
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            839..2142
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1089..1094
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /note="hexamer: TATAAA"
     polyA_site      1114
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /note="major polyA site"
ORIGIN      
        1 aggtagggtt tcgccagaga ccccggaagc gacggcttct cgtctttgct aaggcttctg
       61 gtttttgcta cggtttctga tttcggcttt gggatgggtt gcgacggagg caccatcccc
      121 aagaggcacg agctggtgaa ggggccgaag aaggtcgaga aggttgacaa agacgctgaa
      181 ctggtagccc aatggaacta ctgtacccta agtcaggaaa tcctgaggcg cccaatagtt
      241 gcctgtgagc ttggcagact gtataacaaa gacgcggtca tcgagtttct gttggacaaa
      301 tctgctgaga aggccctggg gaaggcggca tcgcacatca gaagcatcaa gaatgtgaca
      361 gagctcaggc tttctgacaa ccccgcctgg gaaggagata aagggaacac caagggcgac
      421 aagcatgatg acctccagag agcgcggttc atctgccctg tggtgggcct ggagatgaat
      481 ggccggcaca ggttttgctt cctccgatgc tgcggttgtg tgttttctga acgcgccttg
      541 aaggagataa aagctgaagt gtgtcacacg tgtggggctg ccttccagga ggaggacatc
      601 attgtgctca atggcaccaa ggaggatgtg gagatgctga agaagaggat ggaggagagg
      661 aggctgaggg ccaagctgga aaagaaaaca aagaaaccga agacagcgac cgagtgtgcg
      721 tcaaagccgg gtaccacaca agattccgca gggccatcaa aagtgaagtc tggcaagcct
      781 gaggaggcgg accctgatcc tagagagaag aaaagcaccc cggctcccag gggcgcagca
      841 actaatggga gtgcgtctgg gaaagttggc aagcccccat gtggggccct gaagaggtcc
      901 attgcagaca gcgaggagtc tgaaacctac aagtctatct tcaccagcca cagctctgcc
      961 aagcgctcca aggaggagtc tgcgcactgg gtcacccaca catcctactg cttctgaagc
     1021 gggaccgggc cttcaccctg ggtttcccgt ggccttctgt gccacacttg cttggtgtgg
     1081 cactgtgcta taaagctgtc ctctgcagtc ctcagccagc gtggtcactt gctgtgagat
     1141 cttgagggcc ctgggagtga gaagtggtgt gtgacctccc tagtagcagg tccacaggcc
     1201 gtacctctca cctagcctgg tgactgctgc ttctattagg taacaaaaga ctccagctct
     1261 cggtgtacac tcagctcata atggtcaagg agggagtggc cccgagctta gggacagact
     1321 tccaacagtc ttagaccttg ctcctcacag ggttcttctt gcctgatcaa ggactgcaga
     1381 gaggacgcat gcctgactgc ctggtgcaca ctaacatcct ttctctgtct tccttctctc
     1441 tccctccgct atcttggtaa gagaatggca gccatccagg tgccggtggc aggcaggaat
     1501 gactcctttt ccatccccac agttaaaatt gggacctctg tgacacttca tgtggtgtga
     1561 tagatctgcc tctgggctgg gcagatggct cactcagtgg ataaagcact cgccatggac
     1621 acttgtggac cagagtttag atccccagaa cctttatcaa agcccggtga gtgcagtagc
     1681 tgcctgtgat cccagcccct gtaaggcagg gttccctcag caaggcactg agttcagggt
     1741 tcgaggagaa cctgcctcag acactagctg gagtgcagtt gagagattcc cagtgtcagc
     1801 ctctggcctc cacacttaaa gtccctgttc ccaaaccaaa catggtggca tgtctaatcc
     1861 aagcagtcag aagactgagg caggaggatc gccgagatgt cagagctggc aaggttaaat
     1921 agcaaaccct cacctcagga aacaacccca gaaaagcccc tgttcctgct gccctctggt
     1981 ttgctgcttg caggcgatga ggcttggcct caaatacact tgcatttatt ctgggacagt
     2041 gctgggagca tggtaggagt gtgcagcagg gtgggagtga gcatggtcca agggaccctg
     2101 ggcgcatgac ctttgtactt agaaaattga aataaaggtt gt
//
