LOCUS       NP_079818                307 aa            linear   ROD 10-FEB-2025
DEFINITION  replication termination factor 2 [Mus musculus].
ACCESSION   NP_079818
VERSION     NP_079818.1
DBSOURCE    REFSEQ: accession NM_025542.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 307)
  AUTHORS   Conti,B.A., Ruiz,P.D., Broton,C., Blobel,N.J., Kottemann,M.C.,
            Sridhar,S., Lach,F.P., Wiley,T.F., Sasi,N.K., Carroll,T. and
            Smogorzewska,A.
  TITLE     RTF2 controls replication repriming and ribonucleotide excision at
            the replisome
  JOURNAL   Nat Commun 15 (1), 1943 (2024)
   PUBMED   38431617
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK077823.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077823.1, BC049072.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 94.86 cM"
     Protein         1..307
                     /product="replication termination factor 2"
                     /note="likely orthologue of H. sapiens chromosome 20 open
                     reading frame 43 (C20orf43); UPF0549 protein C20orf43
                     homolog; replication termination factor 2
                     domain-containing protein 1; protein RTF2 homolog;
                     replication termination factor 2 domain containing 1"
                     /calculated_mol_wt=33804
     Region          1..290
                     /region_name="Rtf2"
                     /note="Rtf2 RING-finger; pfam04641"
                     /db_xref="CDD:398360"
     Region          193..296
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99K95.1)"
     Site            288
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9BY42; propagated from
                     UniProtKB/Swiss-Prot (Q99K95.1)"
     CDS             1..307
                     /gene="Rtf2"
                     /gene_synonym="1700067C04Rik; 2410001C21Rik;
                     5730427M17Rik; Rtfdc1"
                     /coded_by="NM_025542.2:94..1017"
                     /db_xref="CCDS:CCDS17132.1"
                     /db_xref="GeneID:66404"
                     /db_xref="MGI:MGI:1913654"
ORIGIN      
        1 mgcdggtipk rhelvkgpkk vekvdkdael vaqwnyctls qeilrrpiva celgrlynkd
       61 avieflldks aekalgkaas hirsiknvte lrlsdnpawe gdkgntkgdk hddlqrarfi
      121 cpvvglemng rhrfcflrcc gcvfseralk eikaevchtc gaafqeedii vlngtkedve
      181 mlkkrmeerr lraklekktk kpktatecas kpgttqdsag pskvksgkpe eadpdprekk
      241 stpaprgaat ngsasgkvgk ppcgalkrsi adseesetyk siftshssak rskeesahwv
      301 thtsycf
//
