LOCUS       NM_009105               1607 bp    mRNA    linear   ROD 16-DEC-2022
DEFINITION  Mus musculus Ras suppressor protein 1 (Rsu1), mRNA.
ACCESSION   NM_009105
VERSION     NM_009105.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1607)
  AUTHORS   Porcheri C, Suter U and Jessberger S.
  TITLE     Dissecting integrin-dependent regulation of neural stem cell
            proliferation in the adult brain
  JOURNAL   J Neurosci 34 (15), 5222-5232 (2014)
   PUBMED   24719101
REFERENCE   2  (bases 1 to 1607)
  AUTHORS   Montanez E, Karakose E, Tischner D, Villunger A and Fassler R.
  TITLE     PINCH-1 promotes Bcl-2-dependent survival signalling and inhibits
            JNK-mediated apoptosis in the primitive endoderm
  JOURNAL   J Cell Sci 125 (Pt 21), 5233-5240 (2012)
   PUBMED   22946061
REFERENCE   3  (bases 1 to 1607)
  AUTHORS   Dougherty GW, Chopp T, Qi SM and Cutler ML.
  TITLE     The Ras suppressor Rsu-1 binds to the LIM 5 domain of the adaptor
            protein PINCH1 and participates in adhesion-related functions
  JOURNAL   Exp Cell Res 306 (1), 168-179 (2005)
   PUBMED   15878342
  REMARK    GeneRIF: Rsu-1 interacts with the LIM 5 domain of PINCH1 in
            mammalian cells and functions, in part, by altering cell adhesion.
REFERENCE   4  (bases 1 to 1607)
  AUTHORS   Tsuda T and Cutler ML.
  TITLE     Human RSU1 is highly homologous to mouse Rsu-1 and localizes to
            human chromosome 10
  JOURNAL   Genomics 18 (2), 461-462 (1993)
   PUBMED   8288261
REFERENCE   5  (bases 1 to 1607)
  AUTHORS   Cutler ML, Bassin RH, Zanoni L and Talbot N.
  TITLE     Isolation of rsp-1, a novel cDNA capable of suppressing v-Ras
            transformation
  JOURNAL   Mol Cell Biol 12 (9), 3750-3756 (1992)
   PUBMED   1508180
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX228720.1, AK011857.1 and AI850607.1.
            
            [WARNING] On May 9, 2023 this sequence was replaced by NM_009105.5.
            
            On Mar 13, 2014 this sequence version replaced NM_009105.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009288.1, AK149835.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               CX228720.1         1-107
            108-1261            AK011857.1         1-1154
            1262-1607           AI850607.1         1-346               c
FEATURES             Location/Qualifiers
     source          1..1607
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6-cast"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2"
     gene            1..1607
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /note="Ras suppressor protein 1"
                     /db_xref="GeneID:20163"
                     /db_xref="MGI:MGI:103040"
     exon            1..216
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
     exon            217..328
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
     CDS             220..1053
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /note="rsu-1"
                     /codon_start=1
                     /product="ras suppressor protein 1"
                     /protein_id="NP_033131.2"
                     /db_xref="CCDS:CCDS15693.1"
                     /db_xref="GeneID:20163"
                     /db_xref="MGI:MGI:103040"
                     /translation="MSKSLKKLVEESREKNQPEVDMSDRGISSMLDVNGLFSLAHITQ
                     LVLSHNKLTTVPPNVAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP
                     RGFGSLPALEVLDLTYNNLNEHSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ
                     ILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAENNPW
                     VTPIADQFQLGVSHVFEYIRSETYKYLYGRHMQANPEPPKKNNDKSKKISRKPLAAKN
                     K"
     exon            329..379
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
     exon            380..500
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
     exon            501..619
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
     exon            620..702
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
     exon            703..817
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
     exon            818..950
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1591
                     /gene="Rsu1"
                     /gene_synonym="rsp-1; RsuI"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctggagcca cagctgggaa acagttctcc taatttggga agtgtcaggc cgggaggggc
       61 gtggggttgg ccggattttg tgtgcgcctg cgcgatcgct gggacagggt gtgttcctgc
      121 tgcgggatcc tgttttcggc tgatccagtt catcgctctc cacccgagtt tcccttgcag
      181 gtccctaatc acacccacca ggtgttgctc gctgcgaaca tgtccaagtc actgaagaag
      241 ctggtggagg agagcaggga gaagaaccag ccggaagtgg acatgagtga caggggtatc
      301 tccagtatgt tggatgtcaa cggcttgttc tctctagccc acatcacaca actggtgctc
      361 agccacaaca agctaacaac tgtgccacca aatgtagcgg aactgaagaa cttggaggta
      421 ctaaacttct tcaacaatca gatcgaggaa ctgcctaccc agatcagcag cctccagaaa
      481 ctcaaacacc tgaaccttgg catgaatagg ttgaacacgc tgcctcgagg attcggctcc
      541 ctcccggctc tggaggtcct ggacttaact tacaacaacc tgaatgaaca ttctcttccg
      601 ggaaacttct tctacctcac caccctgcgt gcactctatc taagcgacaa cgattttgaa
      661 atcctgcctc cagatattgg gaagctcaca aagttgcaga tactcagcct cagggataat
      721 gacctgatct cactgcctaa ggaaatcggg gagctgaccc agctgaagga gctccacatt
      781 caggggaacc gcctgaccgt tctgcctcca gagcttggca acttggatct aactggtcag
      841 aagcaggtct tcaaagcaga gaacaacccc tgggttaccc cgattgctga ccagttccag
      901 cttggcgtct cccacgtttt cgaatatatt cgttcagaaa cttacaagta cctctacggc
      961 agacacatgc aagcgaaccc agaacctcca aagaagaata acgacaaatc aaaaaagatc
     1021 agccggaaac ccctagcagc caagaacaaa tgaggagcag acacacacac tggtttctgg
     1081 cctccttcct ccggccttct tgctctgtcc tgcaaatgaa tacagcgtgc tggtgcctac
     1141 ttttcttgtt taaagaaaat ccttttccct ttctcctccc ggtgcttgaa cgcagcctga
     1201 cttttgcacc tttgaaatac ttgtggtagg tggtgccgtt tttataaagt cttacattcc
     1261 ttctcatttg tttccttaaa attgccaaag gcagaaaaca aagctctcat tctcctgcaa
     1321 attccatggt aggcacaggt ttcagtccct tgaataaacg tcacaaggct gcttattatc
     1381 aaaaaataat taaaatcatg taaccgctta aatgtcacag ttaacacttt tcattctttc
     1441 tgtttattca tataactcat tattgtgcct tattaaaaat cttccttcac agccaagcta
     1501 ttatgttcat ttaacttcca aatgatttta ataaaatctt gaatttatat cacacgtttc
     1561 ttcttgacaa aaataaaaaa ataacctagt aaaaaaaaaa aaaaaaa
//
