LOCUS       NM_001083945            1614 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Mus musculus radial spoke 3B homolog (Chlamydomonas) (Rsph3b),
            mRNA.
ACCESSION   NM_001083945 XM_001475820 XM_001481177
VERSION     NM_001083945.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Zhang,X., Sun,J., Lu,Y., Zhang,J., Shimada,K., Noda,T., Zhao,S.,
            Koyano,T., Matsuyama,M., Zhou,S., Wu,J., Ikawa,M. and Liu,M.
  TITLE     LRRC23 is a conserved component of the radial spoke that is
            necessary for sperm motility and male fertility in mice
  JOURNAL   J Cell Sci 134 (20) (2021)
   PUBMED   34585727
REFERENCE   2  (bases 1 to 1614)
  AUTHORS   Zheng,W., Li,F., Ding,Z., Liu,H., Zhu,L., Xu,C., Li,J., Gao,Q.,
            Wang,Y., Fu,Z., Peng,C., Yan,X., Zhu,X. and Cong,Y.
  TITLE     Distinct architecture and composition of mouse axonemal radial
            spoke head revealed by cryo-EM
  JOURNAL   Proc Natl Acad Sci U S A 118 (4) (2021)
   PUBMED   34871179
REFERENCE   3  (bases 1 to 1614)
  AUTHORS   Yan,R., Hu,X., Zhang,W., Song,L., Wang,J., Yin,Y., Chen,S. and
            Zhao,S.
  TITLE     The mouse radial spoke protein 3 is a nucleocytoplasmic shuttling
            protein that promotes neurogenesis
  JOURNAL   Histochem Cell Biol 144 (4), 309-319 (2015)
   PUBMED   26082196
  REMARK    GeneRIF: Results suggest that RSP3 is a nucleocytoplasmic shuttling
            protein and plays an essential role in neurogenesis.
REFERENCE   4  (bases 1 to 1614)
  AUTHORS   Hu,X., Yan,R., Song,L., Lu,X., Chen,S. and Zhao,S.
  TITLE     Subcellular localization and function of mouse radial spoke protein
            3 in mammalian cells and central nervous system
  JOURNAL   J Mol Histol 45 (6), 723-732 (2014)
   PUBMED   25079589
  REMARK    GeneRIF: The subcellular localization and function of mammalian
            RSP3 in mammalian cells and developing CNS.
REFERENCE   5  (bases 1 to 1614)
  AUTHORS   Williams,B.D., Mitchell,D.R. and Rosenbaum,J.L.
  TITLE     Molecular cloning and expression of flagellar radial spoke and
            dynein genes of Chlamydomonas
  JOURNAL   J Cell Biol 103 (1), 1-11 (1986)
   PUBMED   2941441
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK006083.1.
            
            [WARNING] On Feb 19, 2025 this sequence was replaced by
            NM_001083945.2.
            
            On or before Jul 26, 2007 this sequence version replaced
            XM_001481177.1, XM_001475820.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006083.1, AK076872.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 4.51 cM"
     gene            1..1614
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /note="radial spoke 3B homolog (Chlamydomonas)"
                     /db_xref="GeneID:100037282"
                     /db_xref="MGI:MGI:3630308"
     exon            1..379
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /inference="alignment:Splign:2.1.0"
     CDS             267..1436
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /note="radial spoke head-like protein 2B; radial
                     spokehead-like 2B; A-kinase anchor protein RSPH3B"
                     /codon_start=1
                     /product="radial spoke head protein 3 homolog B"
                     /protein_id="NP_001077414.1"
                     /db_xref="CCDS:CCDS57044.1"
                     /db_xref="GeneID:100037282"
                     /db_xref="MGI:MGI:3630308"
                     /translation="MTDRNPRTAEASGLYTYSSRPRAVACQRRRHRDSILQPVEEPMS
                     YGNIMYDRRVIRGNTYALPTGQVPGQPDPLELQRQQQARRRALARKRAQEQLKPRTPE
                     PVEGRKHVDIQTELYLEEIADRIVEVDMECQTDAFLDRPPTPLFIPAKTGKDVATQIL
                     GGELFDFDLEVKPMLEVLVGKTIEQSLLEVMEEEELANLRARQYAYEEIRNVELAEVQ
                     RLEEQERRHREEKERRKKQQWEIVHKRNETLQKISALIFARQYLANLLPSVFDKLRNS
                     GFFYDPIERDIEVGFLPWLMNEVEKSMEHSMVGRTVLDMLIRDVVERRINDYEHKEAM
                     PPGQKTNVINGPNTVTDPSVTTLHTQKPVLDRVSSQPAPSQERKPVEEGGHLMAE"
     exon            380..467
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            468..609
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            610..755
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            756..959
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1122
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1209
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1614
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1577..1582
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /note="hexamer: AATAAA"
     polyA_site      1597
                     /gene="Rsph3b"
                     /gene_synonym="Rshl2b"
                     /note="major polyA site"
ORIGIN      
        1 gaacctcggg ttgctcggca accgatgggg gcgcaactga ctccctccac gttcccgaga
       61 gaaacctgag ggtaccagca acctgctgct ggggccccct cgcgtcccgc ccgcttcccc
      121 gagagcggcg tcctctcggg tcgcagcatc cctgcccttg gcactactta caagtctccg
      181 actacgacga ctccttagcc ccaacctgct tcagagccca ccttcaccgg aggggaagca
      241 gttcgacgct caacaaggcg tcggcgatga cagaccgtaa ccctcggaca gccgaggcct
      301 caggcctcta cacctattcc agcaggcccc gggccgtggc ttgccagcgc cgccgccacc
      361 gagacagcat tttgcagcca gttgaagaac ctatgagtta cgggaacatc atgtatgaca
      421 gaagggtgat ccgaggcaac acctatgcac tgcccacagg acaggtgcct ggacagcctg
      481 atcctctaga gcttcagcga cagcagcagg ccaggagaag ggctcttgcc agaaaacgag
      541 cccaggagca gctcaaacca cgaacgcctg agcccgtgga gggcagaaag catgtggaca
      601 tacaaacaga attatacctt gaagaaattg ctgatcgcat agttgaagtc gacatggaat
      661 gccagacaga tgcgtttctg gacagaccac ccacacccct cttcattcct gccaaaactg
      721 gcaaagatgt ggccactcag atcctgggag gagagctttt cgactttgac cttgaagtca
      781 agcccatgtt agaggttttg gtggggaaga cgattgaaca gtcccttcta gaggtgatgg
      841 aagaggagga gctggccaac ctgcgggcca ggcagtacgc atatgaagag ataaggaacg
      901 tggagctggc cgaagtgcag cgactggaag agcaagagag aaggcaccga gaagaaaagg
      961 agcgccgtaa gaaacagcag tgggagattg tccataagcg gaatgagacg ttacagaaga
     1021 tctcagctct gatattcgct cggcagtacc tggctaacct cctcccgtct gtctttgaca
     1081 aactcaggaa tagtggcttc ttttatgatc caattgaaag agatattgag gtaggattcc
     1141 tcccatggct aatgaatgaa gttgaaaaat ccatggaaca cagcatggtg ggaagaactg
     1201 tgcttgacat gttaattcgc gacgtggttg aaagaaggat caacgattac gagcacaagg
     1261 aagccatgcc gcctggtcag aagacaaatg tgattaatgg tcctaacaca gtgacagatc
     1321 cctcggtgac cacattgcac acgcagaagc cagttttaga cagagtctcc tcacagccag
     1381 caccatccca agaaaggaag cctgtggaag aggggggaca ccttatggca gagtgaccaa
     1441 gagccagaga gcagctcaac atctggtcag ttataatgca aggcaggcac atgacccatc
     1501 caggctttac aaactgtgat actcagccac taaatctttt tgtctagttg gctgaacaaa
     1561 tcaattataa ttaaaaaata aaataaaata aaaatgacac tttttcattt attt
//
