LOCUS       NM_025789               1960 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Mus musculus radial spoke 3A homolog (Chlamydomonas) (Rsph3a),
            mRNA.
ACCESSION   NM_025789 XM_909168
VERSION     NM_025789.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1960)
  AUTHORS   Liu,S., Zhang,J., Kherraf,Z.E., Sun,S., Zhang,X., Cazin,C.,
            Coutton,C., Zouari,R., Zhao,S., Hu,F., Fourati Ben Mustapha,S.,
            Arnoult,C., Ray,P.F. and Liu,M.
  TITLE     CFAP61 is required for sperm flagellum formation and male fertility
            in human and mouse
  JOURNAL   Development 148 (23) (2021)
   PUBMED   34792097
REFERENCE   2  (bases 1 to 1960)
  AUTHORS   Zhang,X., Sun,J., Lu,Y., Zhang,J., Shimada,K., Noda,T., Zhao,S.,
            Koyano,T., Matsuyama,M., Zhou,S., Wu,J., Ikawa,M. and Liu,M.
  TITLE     LRRC23 is a conserved component of the radial spoke that is
            necessary for sperm motility and male fertility in mice
  JOURNAL   J Cell Sci 134 (20) (2021)
   PUBMED   34585727
REFERENCE   3  (bases 1 to 1960)
  AUTHORS   Yan,R., Hu,X., Zhang,W., Song,L., Wang,J., Yin,Y., Chen,S. and
            Zhao,S.
  TITLE     The mouse radial spoke protein 3 is a nucleocytoplasmic shuttling
            protein that promotes neurogenesis
  JOURNAL   Histochem Cell Biol 144 (4), 309-319 (2015)
   PUBMED   26082196
  REMARK    GeneRIF: Results suggest that RSP3 is a nucleocytoplasmic shuttling
            protein and plays an essential role in neurogenesis.
REFERENCE   4  (bases 1 to 1960)
  AUTHORS   Hu,X., Yan,R., Song,L., Lu,X., Chen,S. and Zhao,S.
  TITLE     Subcellular localization and function of mouse radial spoke protein
            3 in mammalian cells and central nervous system
  JOURNAL   J Mol Histol 45 (6), 723-732 (2014)
   PUBMED   25079589
  REMARK    GeneRIF: The subcellular localization and function of mammalian
            RSP3 in mammalian cells and developing CNS.
REFERENCE   5  (bases 1 to 1960)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1960)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Rshl2 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
REFERENCE   7  (bases 1 to 1960)
  AUTHORS   Mager,J., Schultz,R.M., Brunk,B.P. and Bartolomei,M.S.
  TITLE     Identification of candidate maternal-effect genes through
            comparison of multiple microarray data sets
  JOURNAL   Mamm Genome 17 (9), 941-949 (2006)
   PUBMED   16964442
REFERENCE   8  (bases 1 to 1960)
  AUTHORS   Williams,B.D., Mitchell,D.R. and Rosenbaum,J.L.
  TITLE     Molecular cloning and expression of flagellar radial spoke and
            dynein genes of Chlamydomonas
  JOURNAL   J Cell Biol 103 (1), 1-11 (1986)
   PUBMED   2941441
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ173258.1, BC054439.1 and AK148230.1.
            
            On Jan 16, 2008 this sequence version replaced NM_025789.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK148230.1, BC057649.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-332               CJ173258.1         1-332
            333-1908            BC054439.1         1-1576
            1909-1960           AK148230.1         1871-1922
FEATURES             Location/Qualifiers
     source          1..1960
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 4.82 cM"
     gene            1..1960
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /note="radial spoke 3A homolog (Chlamydomonas)"
                     /db_xref="GeneID:66832"
                     /db_xref="MGI:MGI:1914082"
     exon            1..690
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..1747
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /note="radial spokehead-like 2; radial spokehead-like 2A;
                     radial spoke head-like protein 2A; A-kinase anchor protein
                     RSPH3A"
                     /codon_start=1
                     /product="radial spoke head protein 3 homolog A"
                     /protein_id="NP_080065.4"
                     /db_xref="CCDS:CCDS49943.1"
                     /db_xref="GeneID:66832"
                     /db_xref="MGI:MGI:1914082"
                     /translation="MAATNIWAALPAKKRPLHQRARRPAGGRGREPEVPFTTDPSGNP
                     AGRNCLEFLPPGGTSGCSATDGGATVPLALRPFLRERRPLGSQHPCPWHYLQVSDYDD
                     SLAPTCFRAHLHRRGSSSTLNQASAMTDPNPRTAEASGLYTYSSRPRAVACQRRRHRD
                     SILQPVEEPMSYGNIMYDRRVIRGNTYALPTGQVPGQPDPLELQRQQQARRRALARKR
                     AQEQLKPRTPEPVEGRKHVDIQTELYLEEIADRIVEVDMECQTDAFLDRPPTPLFIPA
                     KTGKDVATQILGGELFDFDLEVKPMLEVLVGKTIEQSLLEVMEEEELANLRARQYAYE
                     EIRNVELAEVQRLEEQERRHREEKERRKKQQWEIVHKRNETLQKISALIFARQYLANL
                     LPSVFDKLRNSGFFYDPIERDIEVGFLPWLMNEVEKSMEHSMVGRTVLDMLIRDVVER
                     RINDYEHKEAMPPGQKTNVINGPNTVTDPSVTTLHTQKPVLDRVSSQPAPSQERKPVE
                     EGGHLMAE"
     exon            691..778
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /inference="alignment:Splign:2.1.0"
     exon            779..920
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1066
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1270
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1433
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1520
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1960
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1888..1893
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /note="hexamer: AATAAA"
     regulatory      1898..1903
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /note="hexamer: AATAAA"
     polyA_site      1908
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
                     /note="major polyA site"
     polyA_site      1927
                     /gene="Rsph3a"
                     /gene_synonym="1700012G05Rik; 4930524H12Rik; Rshl2;
                     Rshl2a"
ORIGIN      
        1 tgtgccccag cgcgtaacag agcggggagc caggctgcca agggcgtgtc accgcccggg
       61 gagcctggag cgcggcggcg tggcaggaga agaaacgacc gggggaggcc cttgaaagat
      121 caggagcaca tgggcctgct gggatggcgc tgacagcagc ccccgcgccg ggccaaacgg
      181 cgttaccttc gccccaatgg ccgccaccaa catttgggcg gccctgcctg ccaagaagcg
      241 gccactgcac cagcgcgccc gacgaccagc aggtgggcgg ggccgcgagc cggaagtgcc
      301 ctttactaca gacccttccg gaaacccagc tggccggaac tgcctggagt tcctgcctcc
      361 aggcggaacc tcgggttgct cggcaaccga tgggggcgca actgtccccc tcgcgctccg
      421 cccgtttctc cgagagcggc gtcctctcgg gtcgcagcat ccctgccctt ggcactactt
      481 acaagtctcc gactacgacg actccttagc cccaacctgc ttcagagccc accttcaccg
      541 gaggggaagc agttcgacgc tcaaccaggc ttcggcgatg acagacccta accctcggac
      601 agccgaggcc tcaggcctct acacctattc cagcaggccc cgggccgtgg cttgccagcg
      661 ccgccgccac cgagacagca ttttgcagcc agttgaagaa cctatgagtt acgggaacat
      721 catgtatgac agaagggtga tccgaggcaa cacctatgca ctgcccacag gacaggtgcc
      781 tggacagcct gatcctctag agcttcagcg acagcagcag gccaggagaa gggctcttgc
      841 cagaaaacga gcccaggagc agctcaaacc acgaacgcct gagcccgtgg agggcagaaa
      901 gcatgtggac atacaaacag aattatacct tgaagaaatt gctgatcgca tagttgaagt
      961 cgacatggaa tgccagacag atgcgtttct ggacagacca cccacacccc tcttcattcc
     1021 tgccaaaact ggcaaagatg tggccactca gatcctggga ggagagcttt tcgactttga
     1081 ccttgaagtc aagcccatgt tagaggtttt ggtggggaag acgattgaac agtcccttct
     1141 agaggtgatg gaagaggagg agctggccaa cctgcgggcc aggcagtacg catatgaaga
     1201 gataaggaac gtggagctgg ccgaagtgca gcgactggaa gagcaagaga gaaggcaccg
     1261 agaagaaaag gagcgccgta agaaacagca gtgggagatt gtccataagc ggaatgagac
     1321 gttacagaag atctcagctc tgatattcgc tcggcagtac ctggctaacc tcctcccgtc
     1381 tgtctttgac aaactcagga atagtggctt cttttatgat ccaattgaaa gagatattga
     1441 ggtaggattc ctcccatggc taatgaatga agttgaaaaa tccatggaac acagcatggt
     1501 gggaagaact gtgcttgaca tgttaatccg cgacgtggtt gaaagaagga tcaacgatta
     1561 cgagcacaag gaagccatgc cgcctggtca gaagacaaat gtgattaatg gtcctaacac
     1621 agtgacagat ccctcggtga ccacattgca cacgcagaag ccagttttag acagagtctc
     1681 ctcacagcca gcaccatccc aagaaaggaa gcctgtggaa gaggggggac accttatggc
     1741 agagtgacca agagccagag agcagctcaa catctggtca gttataatgc aaggcaggca
     1801 catgacccat ccaggcttta caaactgtga tactcagcca ctaaatcttt ttgtctagtt
     1861 ggctgaacaa atcaattata attaaaaaat aaaataaaat aaaaatgaca ctttttcatt
     1921 tatttaacat cgttcaaggg ccatgttgtc ttactaataa
//
