LOCUS       NM_001356556            4785 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus rosbin, round spermatid basic protein 1 (Rsbn1),
            transcript variant 2, mRNA.
ACCESSION   NM_001356556 XM_006501402
VERSION     NM_001356556.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4785)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4785)
  AUTHORS   Wang,Y., Iwamori,T., Kaneko,T., Iida,H. and Iwamori,N.
  TITLE     Comparative distributions of RSBN1 and methylated histone H4 Lysine
            20 in the mouse spermatogenesis
  JOURNAL   PLoS One 16 (6), e0253897 (2021)
   PUBMED   34185806
  REMARK    GeneRIF: Comparative distributions of RSBN1 and methylated histone
            H4 Lysine 20 in the mouse spermatogenesis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4785)
  AUTHORS   Sun,H., Shi,Y., Shang,Y., Chen,X. and Xia,F.
  TITLE     MicroRNA-378d inhibits Glut4 by targeting Rsbn1 in vitamin D
            deficient ovarian granulosa cells
  JOURNAL   Mol Med Rep 23 (5) (2021)
   PUBMED   33760197
  REMARK    GeneRIF: MicroRNA378d inhibits Glut4 by targeting Rsbn1 in vitamin
            D deficient ovarian granulosa cells.
REFERENCE   4  (bases 1 to 4785)
  AUTHORS   Brejc,K., Bian,Q., Uzawa,S., Wheeler,B.S., Anderson,E.C.,
            King,D.S., Kranzusch,P.J., Preston,C.G. and Meyer,B.J.
  TITLE     Dynamic Control of X Chromosome Conformation and Repression by a
            Histone H4K20 Demethylase
  JOURNAL   Cell 171 (1), 85-102 (2017)
   PUBMED   28867287
REFERENCE   5  (bases 1 to 4785)
  AUTHORS   Takahashi,T., Tanaka,H., Iguchi,N., Kitamura,K., Chen,Y.,
            Maekawa,M., Nishimura,H., Ohta,H., Miyagawa,Y., Matsumiya,K.,
            Okuyama,A. and Nishimune,Y.
  TITLE     Rosbin: a novel homeobox-like protein gene expressed exclusively in
            round spermatids
  JOURNAL   Biol Reprod 70 (5), 1485-1492 (2004)
   PUBMED   14724137
  REMARK    GeneRIF: Rosbin is associated with and is most likely
            phosphorylated by protein kinase A. We suggest that it plays an
            important role in transcriptional regulation in haploid germ cells.
REFERENCE   6  (bases 1 to 4785)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124698.4 and AC162922.4.
            
            On Oct 8, 2017 this sequence version replaced XM_006501402.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB101658.1, SRR1660811.150588.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1034              AC124698.4         130800-131833
            1035-1708           AC124698.4         145031-145704
            1709-1846           AC162922.4         143960-144097
            1847-1989           AC162922.4         144428-144570
            1990-2157           AC162922.4         150326-150493
            2158-2266           AC162922.4         151796-151904
            2267-2722           AC162922.4         152483-152938
            2723-4785           AC162922.4         154897-156959
FEATURES             Location/Qualifiers
     source          1..4785
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 45.52 cM"
     gene            1..4785
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /note="rosbin, round spermatid basic protein 1"
                     /db_xref="GeneID:229675"
                     /db_xref="MGI:MGI:2444993"
     exon            1..1034
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /inference="alignment:Splign:2.1.0"
     CDS             332..2719
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /note="isoform 1 is encoded by transcript variant 2; round
                     spermatid basic protein 1; lysine-specific demethylase 9"
                     /codon_start=1
                     /product="lysine-specific demethylase 9 isoform 1"
                     /protein_id="NP_001343485.1"
                     /db_xref="CCDS:CCDS17697.1"
                     /db_xref="GeneID:229675"
                     /db_xref="MGI:MGI:2444993"
                     /translation="MFRSTRTTDQWRVGERLQCPAGHARAALARTADGGAVGPFKCVF
                     VGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHVGVSPRGVKRQRRASSGGSQEKRGRP
                     SQDPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPTVAAP
                     LPAPGTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGSDGDPGACVPGDLKHKDKQE
                     NGERSGGVPLIKAPKRETADENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNK
                     EVQTVCAGLTRISKEILTQGQLNSTSGVNKESFRYLKDEQLCRLNLGMQEYRVPQGVQ
                     TPFTTHQEHSIRRNFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFS
                     EEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIET
                     TTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTL
                     PWGTLSSLQLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPR
                     TSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHA
                     EDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNV
                     IHQFKTVSAVCSLAWHIRLKQYHPVVETAQNTESNSNMDCGLEVDSQCVRIKTESEER
                     CTEMQLLTTASPSFPPPSELHLQDLKTQPLPVFKVESRLDSDQQHSLQAHPSTPV"
     exon            1035..1708
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1846
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1847..1989
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1990..2157
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /inference="alignment:Splign:2.1.0"
     exon            2158..2266
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /inference="alignment:Splign:2.1.0"
     exon            2267..2722
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /inference="alignment:Splign:2.1.0"
     exon            2723..4785
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4743..4748
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /note="hexamer: AATAAA"
     regulatory      4747..4752
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /note="hexamer: AACAAA"
     polyA_site      4769
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
                     /note="major polyA site"
     polyA_site      4783
                     /gene="Rsbn1"
                     /gene_synonym="C230004D03Rik; E330004N01; KDM9; mKIAA3002;
                     Rosbin; Rsbn; Rsbp"
ORIGIN      
        1 cctccgggca agatgaagga ggaacactgg aagtggagcg cctgaacaca cggcgagact
       61 ctgaaagcta ttaacattgt ttgggcggtt agggcggttg gcggcaactc gccggagggc
      121 ggcagttgcg tggcaccccg aagcgtgcct aggcgcacgc tcccctccgc tcctccactc
      181 agagagcaaa gtgggggcgg agggggaggg ggaagaacgc gaagggcggt ggaactacaa
      241 ctcccgcaag gccttgcgcg tccagggtgc tttacaatag aagctcggtt ggcgaggtct
      301 gcggagaggt gtcggaactg ccgtttccgg catgttcagg tctacgagaa cgaccgatca
      361 gtggagggtg ggggagagac tccaatgccc agcgggccat gcgcgggcag cgcttgcgcg
      421 aaccgcggac gggggggcgg tcgggccatt taaatgtgtg tttgtgggtg aaatggctgc
      481 gcaggtcgga gcggttcgcg tagtacgggc ggtggcggcg caggaggagc cggacaaaga
      541 agggaaggag aaaccccatg ttggggtttc gccgcgggga gtgaagcggc agcgccgggc
      601 gagcagcggg ggttctcagg agaagcgggg gcggccgagc caggaccccc ctctcgctcc
      661 ccctcatcgg cggcgtcgta gccgccaaca tcccgggccg ctgcctccaa cgaatgccgc
      721 cccaaccgtc ccgggccctg ttgaacctct gctcctgccg cctccgccgc caccgtcgct
      781 ggcacccgcc gggcccactg tcgctgcccc gctcccggcc ccgggcacct cggccctctt
      841 caccttctcg cctctgacgg tgagcgcggc cgggcccaag cataagggcc acaaggagcg
      901 gcacaagcac catcaccacc gcggctccga tggtgacccc ggcgcctgcg ttccgggcga
      961 tctcaagcac aaggacaagc aggaaaacgg cgaaaggagc ggaggggtgc ctctgatcaa
     1021 ggcccccaag agagaaacag cagatgaaaa tggtaaaacc cagagagctg atgattttgt
     1081 cttgaagaaa ataaagaaga aaaagaaaaa gaaacatcga gaagacatga gaggaagacg
     1141 ccttaaaatg tacaataagg aagtacaaac cgtctgtgct ggcctgaccc gcatcagcaa
     1201 agaaattctc acccaaggac agctaaatag cacttcagga gttaataagg agtccttcag
     1261 gtatttgaag gatgaacagc tgtgcagatt aaatttgggc atgcaagaat atcgggtgcc
     1321 ccagggagta cagacacctt ttacaacgca ccaagaacat tctattcgca gaaatttctt
     1381 aaaaacaggt actaaattta gcaactttat tcacgaagaa caccagtcca atgggggtgc
     1441 tcttgtcctt catgcataca tggacgaact ctcatttttg tctccaatgg agatggagag
     1501 attttctgag gagtttcttg ctttgacatt cagtgaaaat gagaaaaacg ctgcgtacta
     1561 tgcgttagca atagtgcatg gagcggccgc ttatctccca gacttcttgg actactttgc
     1621 ttttaatttt cccaacactc cagtgaaaat ggaaattttg ggcaagaaag atattgaaac
     1681 aaccaccatt tcaaattttc atactcaggt caacaggaca tattgctgtg gtacctaccg
     1741 agcaggtcct atgcggcaga taagtcttgt tggagcagta gatgaagaag ttggtgatta
     1801 tttcccagag ttcctagata tgctagaaga atcaccattt ctgaaaatga ctttgccctg
     1861 gggtacactt tccagcctcc agctacaatg taggtctcag agcgatgacg ggcctataat
     1921 gtgggtgagg ccaggagaac agatgatccc tacagcagat atgccaaagt cacccttcaa
     1981 aagacgacga tcaatgaatg aaattaaaaa tctccagtac ctacctcgga caagtgaacc
     2041 ccgagaagtc ctctttgaag acaggaccag agctcatgct gatcatgtag gtcaggggtt
     2101 tgactggcaa agtacggctg ctgttggggt tttgaaggct gtacaattcg gtgaatggag
     2161 tgatcagcct cgcataacca aagatgtgat ttgttttcat gctgaggatt ttactgatgt
     2221 tgtacagaga cttcagttag accttcatga acctccagtt tctcagtgtg tacagtgggt
     2281 ggatgaagca aaactaaacc aaatgaggcg agaaggcatt cgctatgcta gaattcagct
     2341 ttgcgacaat gatatctact tcatccctag aaatgtcatt catcagttca aaacagtgtc
     2401 agcagtatgc agcctagcct ggcatataag gcttaaacaa taccaccctg ttgtggaaac
     2461 cgctcaaaac acagagagca attccaacat ggattgtggt ttagaagttg actcccagtg
     2521 tgtgagaata aaaactgaat ctgaggaaag atgcacagag atgcagcttt tgacaactgc
     2581 ttcaccgtct ttcccacctc catcagaact tcatctacag gatctgaaga ctcagcctct
     2641 tccagttttc aaggtggaga gcagactgga ctctgaccag caacacagtc tgcaggcaca
     2701 tccaagcact cctgtgtgac atatccgatt tccccacctc ccacttgcca tccagcagat
     2761 gccatcctgt catctaagct ggtcattact aatacacaag gagactgtct cctgacagcc
     2821 agcactgtgc aatcactcag gaaccagcgg atctgcaaag acctacaatc aaacgcaaat
     2881 ctccattttc cttttacaaa gcattctacc ctcacttcca gtataaacat attaaaagaa
     2941 tataaaaatg ttgaaaatca tgtactaatg aagtcattgt atattagatt gcaatagaat
     3001 ggaaagacac atttagctag taatgtacct ggaaatcctg aatgtcctac gtgagtatta
     3061 gattttgata gcatgcttta aagactgatg aatataaaag cagaagcttc gagtttcctg
     3121 ctgctttcaa aactgtgtcc tagttgagtg atacaaatga tcgcaagttt tctaaatcat
     3181 taaactattt ggttggtgga gtgaggcatg gtctggtatc ctctgatttg taaaatagcg
     3241 atggcagtga agttgtaact gaaattgaag ctgatcttcc tttctggtat gttatctatt
     3301 gtgccagccc ttgagattac ttgcagaatg tggctataag ttttagtagt ttatggatca
     3361 gagggatatt tttaaaatat gctaatcgaa agaacctagt aaattaaata ttcctaacag
     3421 caaatagaat gattttatgg taaccattaa aaagaataag tcttcccctg tcccagaggt
     3481 cattctataa ttatcaagat aggataagag ttagggttac gattctgaga gatgtcccaa
     3541 attcataaag caataataat aacctttata ttggttccct cttccaaagt ttaactcttg
     3601 agaaatgaat tcttagtctt aattgtactt tgcttattca gtacttacag ttttacatga
     3661 tttttactct aagacttttg gaaagtgccc tgcgccctca gaaacagtcg gactattagt
     3721 tcacaaatac tacaagctct tgtatgggga aaagagctta ttttaaataa tttgctaaac
     3781 tttaggaaat gatatatcag tcttaacagg cataaagatc tcacctaatg acttgagaaa
     3841 cttttgctta gtgctttttt tcccctgtat aaatattgtc tagaaggaaa gttaatatag
     3901 gaacaagact ccaaaatcca cgaaaatatg ttcctagtga atatatcctt tatcattaat
     3961 attagcccat tatattttca tctgtatttg ccttttaaat ttatttgcat ctattaaaga
     4021 taattaggat tactgagttt gtgtttttct aataaatctg tttcatcctt tcagtagcac
     4081 atgccagagg ctcacatttg tgctaagttt catgtttcaa gacagtctgt agccgtattt
     4141 actggtcatg caagtagagg agatacacat caccagtgtt tttcttaagt gcataaagga
     4201 cttatcctcg tcctggaagt ctgttgcttt aaaagcaagt atccataaac attatggcct
     4261 tccatttaaa aaatctccat acatttttta ggatccactt gtgcatgtag ttgagaccac
     4321 cgtctcttaa aatatagcac ttttcaattc tctctaaaga aatacttatg taatactatc
     4381 acacgttgta aattttcatg taatagtgtt ttctgtgact aaacttcatt ttgattggca
     4441 gctaagactt tttttcctgt ggctttaatt tatctaagag gtctttgcat atagatgaaa
     4501 tgtttaattt gcctggcgga ctatttgcgt ttgtgtggcc ttagtttgtt tattgacatt
     4561 aacaagtgtt ttaaaaggtt tttaatggat agtcttaaat ctcaaatttg tgtgaataat
     4621 aattctttta acacagtgct tttttgtagc tgtctgagtg tgttaaattg ttaagctatt
     4681 tctttgtaaa gtaggacaat ggaatgcata ggtttctttt ttttcctgta aagtattttt
     4741 ttaataaaca aagtctgatt tgtcctttac tgatgtttca aaatg
//
