LOCUS       NM_001013381            4167 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus radical S-adenosyl methionine domain containing 1
            (Rsad1), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001013381 XM_484063
VERSION     NM_001013381.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4167)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4167)
  AUTHORS   Mohan,R.A., Bosada,F.M., van Weerd,J.H., van Duijvenboden,K.,
            Wang,J., Mommersteeg,M.T.M., Hooijkaas,I.B., Wakker,V., de Gier-de
            Vries,C., Coronel,R., Boink,G.J.J., Bakkers,J., Barnett,P.,
            Boukens,B.J. and Christoffels,V.M.
  TITLE     T-box transcription factor 3 governs a transcriptional program for
            the function of the mouse atrioventricular conduction system
  JOURNAL   Proc Natl Acad Sci U S A 117 (31), 18617-18626 (2020)
   PUBMED   32675240
REFERENCE   3  (bases 1 to 4167)
  AUTHORS   Khan,R.S., Baumann,B., Dine,K., Song,Y., Dunaief,J.L., Kim,S.F. and
            Shindler,K.S.
  TITLE     Dexras1 Deletion and Iron Chelation Promote Neuroprotection in
            Experimental Optic Neuritis
  JOURNAL   Sci Rep 9 (1), 11664 (2019)
   PUBMED   31406150
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4167)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4167)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   6  (bases 1 to 4167)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 4167)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB645699.1, AK148401.1, BC056485.1 and AW060343.1.
            
            On Dec 18, 2007 this sequence version replaced NM_001013381.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK148401.1, BC139274.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 BB645699.1         2-9
            9-823               AK148401.1         4-818
            824-4147            BC056485.1         154-3477
            4148-4167           AW060343.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..4167
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 58.9 cM"
     gene            1..4167
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /note="radical S-adenosyl methionine domain containing 1"
                     /db_xref="GeneID:237926"
                     /db_xref="MGI:MGI:3039628"
     exon            1..225
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     exon            226..359
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     exon            360..564
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     exon            565..930
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     exon            931..994
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1142
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1197
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     exon            1198..1301
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..4151
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4127..4132
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /note="hexamer: AATAAA"
     polyA_site      4147
                     /gene="Rsad1"
                     /gene_synonym="B430319G23"
                     /note="major polyA site"
ORIGIN      
        1 agggctatcc acgcggccca gccccgggta cacccctgct gggcacgctg tcgaggtctc
       61 gcatccctcc tttctgccgc cttgcgcgcc atggttccct ccggggtccg gaccggcaga
      121 tgggtggcag cggccagggc ggcccagcgg cgcccccgtg tggacagctt gggacagcct
      181 ccgagtcctg agtccgcgag cacgcgtgcg gcgctttacg tgcactggcc ttattgcgag
      241 aaacgctgca gctactgcaa cttcaataag tacatccccc gcggcgtgga ggaggggacc
      301 gtgcggaatt gcctggtgac tgaggcaagg acgctgctgc ggctcagcgg ggtgcagaga
      361 gtagagtctg tgttctttgg tggaggaacc ccgagtctgg ccagtcccca cactgtggct
      421 gctgtcctgg aggctgtggc tcaggaagtc tacctgcctg ccgattcgga agtcaccttg
      481 gaggctaacc ccacttcagc cccaggtcct aggctggcag cttttggagc agcaggagtg
      541 aacaggttgt ccattggttt acagtccctg gatgacgcgg agctgcagct gctgggccgg
      601 actcactcag ccagcgacgc tttacggact ctggcggaag cccggctcct tttccctggc
      661 agagtgtcgg tggatttgat gctggggtta ccggcacaga aggtggagcc gtggcttcaa
      721 cagcttcaga aactgctgta ccactgtgac gaccacctct ccctctacca gctgaccctg
      781 gaacggggca cctcactctt tgcccaggtg cagcagggta ccctcccggc ccctgacccg
      841 gacctggctg ctgagatgta ccaggagggc aggacagtcc ttcgagatgc tggctttcgc
      901 caatatgagg tctccaattt tgcacggaac ggggcgctca gtacccataa ctggacgtac
      961 tggcagtgcg gtcagtacct tggcattggg cctggagccc atggaagatt tgtgccccag
     1021 ggaactggag gccatacccg ggaagcacgg atccagacac tggagccaga caattggatg
     1081 aaagaggtga cgctctttgg tcatggcacc cggaagtgcg ttcgcctggg aaagctggaa
     1141 ctgctagagg aggttttggc tatggggctg cgtactgatg ttggagtcac tcaccagcac
     1201 tggcagcagt ttgagcccca gctgaccctg tgggacgtgt ttggagcaag caaggaggtg
     1261 gaggagctgc tagctcaggg tctgctgctg ctggattaca ggggtctccg gtgttcctgg
     1321 gagggcctag ctgtgctgga ctccctgtta ttgaccctcc tacctcaact ccaagaggcc
     1381 tggcagcaca ggccttcctc acccgtgtca ggaggatgac cagacatcct tgtatcatga
     1441 ggaagcacca gttggactta gagggctggg ccagatggtg ggcatctgcc ggtaggtgcc
     1501 atctctgctc tgaggtgcta ttgcttggct ctgacacccc catgggaatg gatgtggtca
     1561 gttggatgga cggctgcctc tgttctgggg actggtatcc ctcacagcat cccaggagtc
     1621 acaggtcagc aagtgttccc tgcctaggat gtcctcacca ccccactccc accccccgcc
     1681 actggctttt gttgactttt ttggacacca aataacacaa aatctttcta cagggaattg
     1741 tatctatcag agaagcctca ttctagagag aagccctagc ttgtatggtt cagtagaact
     1801 aaatcccctc caggtacctt acacagaaga aatataggaa caagatgttt acaaaaccat
     1861 ttgaagggct ggagagatgg cttggtggtt tgctcttcta gagaaccagg gttcaagtcc
     1921 cagcagccat gtggcagctc acaaccatca gtaactctca ttccagggga tccggcacct
     1981 tcttttcacc tcttcgtgta ccagacacct gtgtggtgca tagatattca tctaggcaaa
     2041 acactcatat gcataaaata aaaagaaata aatctaaaaa aaatattttt atccaaggcc
     2101 acttgttgta cagaaatgta acctatactc tatgtatgtc tcattatttc ctaagggttg
     2161 aattcaggtt caaagtttta aacattattt tcatttttat tatttatttg gattttcaag
     2221 atggggtctc tctgtgtggc cttggtcctg gagctcacac tgtagaccag gcttgtctag
     2281 aactcagaga tctgcttgcc tttctttgcc ttccgaatgt agggattaaa ggcttgcacc
     2341 aatactgccc acattttatt aaagtgtgtg tgtgtgtgtg tgtgcgcgcg cgcgcgcgcg
     2401 cgcgcgcgtg tgtgcgtgca gccatggagg ccagagtaga gtgttgtatc ttctggagac
     2461 agagttacag aggaatgaat gtgagccatc ttttctgagc accacactct ggtcctctgg
     2521 aagagcaggg agcactctct cctgctaagc tatttctcca gcttctattt tgaatgtaaa
     2581 agattgtggg gttttttttc cccctgagac agtgccatat gtacccgaca ctgcaaactc
     2641 actgtgtggc tgaggacagt gtttagcatc ggaccccctg cttctgcctc ccgagtgctg
     2701 agatcacggg catgcaccac cacacccatt tttctgtggt tctggacttc atgcgctgag
     2761 gcaaacacca ctatctaaat ccccaaccct atcaggttca gtattattat ttttttaatt
     2821 tagatttatc tttcttacta tttaagtatt ttgtgtgcat gcctttgaat gtgcacacca
     2881 tgcgtgtgcc tgttggatcc cctggaactg ggcttgcgga tggttgtgag ccacaatgtg
     2941 ggtgctggtt attgaatgtg ggtcctctgc cagatcaaat aagtgccctt aactgttgag
     3001 ccatctctcc agccccgagg gtaatagtgc acagctgcat ctttcctttg aaattaagga
     3061 gttcattatc ttggcttgag accatgagac caaatgtccc atcgcctgat aatcatttga
     3121 ccagtgactt tagcacctac tagtgattct ttcccaaatt acttttaaaa tttacatttg
     3181 tatttttaaa catttactta tgtctacaat tgctctatct gcatgtacac ctgtatgcca
     3241 gaagaggacc tcagatcaca ctatagatgg ttatgggcca ttacattggt gctgggaatt
     3301 gaactcagga cctctggaag agcagacagt gctcttaacc actgagccat ctctccagcc
     3361 tcaaacttag gtattttatg tatatgagtg ctctatttgt atatatgcct gcatgacaga
     3421 agaggacatc agattatata taaatggttg tgagcaacca tgtggttgct gggaattgaa
     3481 ctcaggacct atggaagagc accctgtgct cttatctgct gagccatctc tccagcctag
     3541 ccaaatcatt tcttaaattg aggattgcaa agtattggtt tctgattcta ttattccttc
     3601 caaattaatt attttccatt ttccccataa aaaagaactt tcctctgtta ttgttacaat
     3661 gttaagaatc agacctatgg ccttgttcaa gccagacaac ctccttctat ggtaggaatc
     3721 tcaaacctgt aaattcctaa ccctgtaaca ggctcatccc atcgaataga ccttaggttg
     3781 tcagactccc tggacggggg gggggggggg ggcgctgcca taatgggtat gtctcaacta
     3841 gatgtgtcct tgctcttcag agggacatat ttcttcctga taacgcaaga ccttttttct
     3901 tctcccctgc cgcctgcagg ggaatcagag acagtctggt gatgtgaaac ctcccccttc
     3961 tactgagatc tataggaagg ggccccccac tctaccctgg ggaacttgga tcctcttcag
     4021 aaccctacca tgttgtctgt gtgtctatga cactggggct tgaatgttcc cgctactgta
     4081 cactgtgccg ctgtgcctgt gtgtctgtgg tactgataat tctcttaata aatctcttac
     4141 cccaaaagac aaaaaaaaaa aaaaaaa
//
