LOCUS       NM_026041               1228 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus ribosomal RNA processing 15 homolog (Rrp15), mRNA.
ACCESSION   NM_026041
VERSION     NM_026041.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1228)
  AUTHORS   Deng,Z., Xu,Y., Cai,Y., Lin,W., Zhang,L., Jiang,A., Zhou,Y.,
            Zhao,R., Zhao,H., Liu,Z. and Yan,T.
  TITLE     Inhibition of Ribosomal RNA Processing 15 Homolog (RRP15)
            Suppressed Tumor Growth, Invasion and Epithelial to Mesenchymal
            Transition (EMT) of Colon Cancer
  JOURNAL   Int J Mol Sci 24 (4), 3528 (2023)
   PUBMED   36834940
  REMARK    GeneRIF: Inhibition of Ribosomal RNA Processing 15 Homolog (RRP15)
            Suppressed Tumor Growth, Invasion and Epithelial to Mesenchymal
            Transition (EMT) of Colon Cancer.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1228)
  AUTHORS   Wu,T., Hu,S., Qiao,X., Luo,H. and Wu,J.
  TITLE     Tissue-specific expression of Riken 2810430M08 and its function in
            T-cell immune responses
  JOURNAL   J Cell Biochem 101 (1), 89-98 (2007)
   PUBMED   17163456
REFERENCE   3  (bases 1 to 1228)
  AUTHORS   De Marchis,M.L., Giorgi,A., Schinina,M.E., Bozzoni,I. and Fatica,A.
  TITLE     Rrp15p, a novel component of pre-ribosomal particles required for
            60S ribosome subunit maturation
  JOURNAL   RNA 11 (4), 495-502 (2005)
   PUBMED   15769876
  REMARK    GeneRIF: the budding yeast homolog of Rrp15 is required for
            maturation of 60S ribosomal particles.
REFERENCE   4  (bases 1 to 1228)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK169088.1 and CO043575.1.
            
            On Feb 28, 2007 this sequence version replaced NM_026041.1.
            
            Summary: This gene encodes a protein similar to budding yeast
            Rrp15p. Rrp15p is a component of pre-60S ribosomal particles in
            budding yeast, and is required for the early maturation steps of
            the 60S subunit. The mouse genome contains at least one pseudogene
            on the X chromosome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK169088.1, AK013204.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-920               AK169088.1         2-921
            921-1228            CO043575.1         1-308               c
FEATURES             Location/Qualifiers
     source          1..1228
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 89.95 cM"
     gene            1..1228
                     /gene="Rrp15"
                     /gene_synonym="2810430M08Rik; 5430437H21Rik"
                     /note="ribosomal RNA processing 15 homolog"
                     /db_xref="GeneID:67223"
                     /db_xref="MGI:MGI:1914473"
     exon            1..195
                     /gene="Rrp15"
                     /gene_synonym="2810430M08Rik; 5430437H21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            196..455
                     /gene="Rrp15"
                     /gene_synonym="2810430M08Rik; 5430437H21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            456..553
                     /gene="Rrp15"
                     /gene_synonym="2810430M08Rik; 5430437H21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            554..752
                     /gene="Rrp15"
                     /gene_synonym="2810430M08Rik; 5430437H21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            753..1213
                     /gene="Rrp15"
                     /gene_synonym="2810430M08Rik; 5430437H21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1191..1196
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rrp15"
                     /gene_synonym="2810430M08Rik; 5430437H21Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1213
                     /gene="Rrp15"
                     /gene_synonym="2810430M08Rik; 5430437H21Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtgtgttgca acacgacgga attatcaggt ggcacttccg gcgagccaag atggctgcgg
       61 ccgttcagga ctcacgtgtg agcccagggg agatactgaa gcgttctccg aagaagaaga
      121 aaaagatgaa gatggtagcc aaggctgcag cgtcgaagct agaagatgag gtcaaagact
      181 cttctgatgg agaaggaagc tgtgactcag agatggacca ctcagatgat ggagctgcag
      241 aagcagacag tgaggacaat gttgaatcct gtgaggaaga caatgaagac gccgcagagt
      301 cgagtgctgg gaccaattca ggctgggcag atgccatggc aaaaatcctt aacaaaaaga
      361 ctcctaaaag caaagccacc atcctcacca aaaacaaaga gctggagaag gagaaggaga
      421 agctaaagca ggagaggctg gagaaaagga agcagcttga taagaagcgg gagtgggaaa
      481 tgctgtgcag agtgaagcca gatgttgtca aagacaaaga ggcagagagg aaccttcaga
      541 ggattgcgac aaggggtgtg gtgcagctct tcaatgctgt tcagaaacac caaaggaatg
      601 ttggcgaaaa ggttaaggaa gcaggaggct ccgtccgcaa gcgagccaag ctgatgtcaa
      661 ctgtttccaa gaaggatttc atcagtgttc ttcgaggaat ggatggtaca agtaggaaca
      721 gtcctgctgg gaagagcccc aaagccagac agactgaagt gaaatcagaa gagagcccag
      781 ggtggaagat tctgcgagat gatttcatga tgggagccag catgaaggac tgggacaagg
      841 agagcgaggg cgaggagcct gctggtggca gggcagaggc cgcagccagc cgttgagcgg
      901 cagacgggag catccagctc cgctgcaaat gacccgacgg ttgggagcct gcgcatggcc
      961 atctgccaaa tgctaggact tcctgagaac ctgtgctcta gggttcctca ggtgcagact
     1021 gtattaaagc tgtattttta attcttacag aaatttaacc tgtttttcta aaatatttgt
     1081 acagagaaat attttttttc ttgagcagta aactgcaatt ttctaggatc ctttgctgtg
     1141 gacacatgcc catcatccat cagggtttct aaagtgcggt cccatttata attaaagtga
     1201 atttgatatg aaaaaaaaaa aaaaaaaa
//
