LOCUS       NM_010925               2008 bp    mRNA    linear   ROD 03-FEB-2024
DEFINITION  Mus musculus ribosomal RNA processing 1 (Rrp1), mRNA.
ACCESSION   NM_010925
VERSION     NM_010925.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2008)
  AUTHORS   Yu,X., Bauer,K., Koczan,D., Thiesen,H.J. and Ibrahim,S.M.
  TITLE     Combining global genome and transcriptome approaches to identify
            the candidate genes of small-effect quantitative trait loci in
            collagen-induced arthritis
  JOURNAL   Arthritis Res Ther 9 (1), R3 (2007)
   PUBMED   17244351
REFERENCE   2  (bases 1 to 2008)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   3  (bases 1 to 2008)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
REFERENCE   4  (bases 1 to 2008)
  AUTHORS   Wiltshire,T., Pletcher,M., Cole,S.E., Villanueva,M., Birren,B.,
            Lehoczky,J., Dewar,K. and Reeves,R.H.
  TITLE     Perfect conserved linkage across the entire mouse chromosome 10
            region homologous to human chromosome 21
  JOURNAL   Genome Res 9 (12), 1214-1222 (1999)
   PUBMED   10613844
REFERENCE   5  (bases 1 to 2008)
  AUTHORS   Cole,S.E., Wiltshire,T., Rue,E.E., Morrow,D., Hieter,P., Brahe,C.,
            Fisher,E.M., Katsanis,N. and Reeves,R.H.
  TITLE     High-resolution comparative physical mapping of mouse chromosome 10
            in the region of homology with human chromosome 21
  JOURNAL   Mamm Genome 10 (3), 229-234 (1999)
   PUBMED   10051316
REFERENCE   6  (bases 1 to 2008)
  AUTHORS   Jansen,E., Meulemans,S.M., Orlans,I.C. and Van de Ven,W.J.
  TITLE     The NNP-1 gene (D21S2056E), which encodes a novel nuclear protein,
            maps in close proximity to the cystatin B gene within the EPM1 and
            APECED critical region on 21q22.3
  JOURNAL   Genomics 42 (2), 336-341 (1997)
   PUBMED   9192856
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY106122.1, BC065993.1 and BY616845.1.
            
            [WARNING] On Mar 20, 2024 this sequence was replaced by
            NM_010925.3.
            
            On Nov 10, 2006 this sequence version replaced NM_010925.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065993.1, U79774.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                BY106122.1         1-38
            39-1982             BC065993.1         1-1944
            1983-2008           BY616845.1         412-437
FEATURES             Location/Qualifiers
     source          1..2008
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..2008
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /note="ribosomal RNA processing 1"
                     /db_xref="GeneID:18114"
                     /db_xref="MGI:MGI:1203500"
     exon            1..224
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..1576
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /note="protein NNP-1; RRP1-like protein; nucleolar protein
                     Nop52; novel nuclear protein 1; ribosomal RNA processing 1
                     homolog"
                     /codon_start=1
                     /product="ribosomal RNA processing protein 1 homolog A"
                     /protein_id="NP_035055.2"
                     /db_xref="CCDS:CCDS35961.1"
                     /db_xref="GeneID:18114"
                     /db_xref="MGI:MGI:1203500"
                     /translation="MVPGVPLPPEIQLAQRLAGNEQVTRDRALRKLRKYIEARSQRAT
                     GGFTPDELLKVWKGLFYCMWMQDKPLQQEELGRTIAQLVHAFHTTEAQHQFLKAFWQT
                     MIREWVGIDRLRLDKFYMLMRMVLSESLKAVKARGWDERQIEQLLELLTTEILNPDSQ
                     APSGVKSHFLEIFLEELAKVGAAELTADQNLQFIDPFCQIAARTKDSQVLHKIIQSIF
                     QTIVEQAPLAIEDIMNELDTQSGEGEASDGDDGEASDGDDGEASDDDDGEASDGGDGD
                     VADSDDSDGADDDDGDVSDGDGGDNDEGDSNKSSEGEQDLQDTPPKKLPAGTAHRAGP
                     EADKEQAWDDEENAGPVLQFDYEALANRLFKLASRQSTPSQNRKRLYKVIQKLRELAG
                     GTFPEDDVPEKAYKKMLEGRRERKKKKKRLPKPQPQNKEAGSEAESSSADPGPGRKRK
                     RNRKTDEKAGQGGPPGKRRKPGARAKGAGAQQPKKRIQSSQSAE"
     exon            225..307
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            308..365
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            366..451
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            452..513
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            514..643
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            644..708
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            709..1070
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1150
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1248
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1268
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1385
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..2008
                     /gene="Rrp1"
                     /gene_synonym="NNP-1; Nnp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcagtgtgac gttcagtggt gacgagcgcg tgtcgtcact cgagcgcccc agcggaagcg
       61 tcgagtgcgt ggtctcaggg ttctcctcac catggttccc ggagtgccgc tcccgccgga
      121 gatccagctg gcgcagcgcc tggcgggcaa tgaacaggtg acgcgggacc gcgcgttgcg
      181 gaagctgcgg aagtacatcg aggccaggtc gcagcgggcg acaggtggtt tcactccaga
      241 tgaactgcta aaagtatgga aaggactgtt ttactgcatg tggatgcagg acaagcccct
      301 ccagcaggaa gaactaggaa ggaccattgc ccagcttgtc catgcttttc acacgacgga
      361 ggcacagcac cagttcctga aggccttctg gcagaccatg atccgggagt gggtgggcat
      421 tgacagactg cgcctggata agttctacat gctcatgagg atggtcctaa gtgagtcact
      481 gaaggctgtg aaagcccggg gatgggacga gagacagatt gagcagctgc tagagctgct
      541 aaccaccgag atcctgaacc ccgacagcca ggcccccagt ggggtgaaga gccacttcct
      601 agagatcttt ctggaggagc tggccaaagt gggcgctgca gagctcaccg cagaccagaa
      661 tctgcagttc atcgacccct tctgccagat agcagcccgc actaaggatt cccaggtttt
      721 gcataagatc attcagagca tctttcagac gattgtggag caggctccct tggccataga
      781 agacatcatg aatgaactgg acacacagag tggagagggt gaagcatcag atggtgatga
      841 tggtgaagca tcagatggtg atgatggaga agcatcagac gatgatgatg gtgaagcgtc
      901 agatggtggt gatggtgatg tggcagacag tgatgatagt gatggggcag acgatgatga
      961 tggtgacgtg tcagacggtg acggtggtga caatgatgaa ggtgacagta acaagtcctc
     1021 agagggtgag caggatctgc aagacacacc acccaagaag ctgcctgcag gcaccgcaca
     1081 tagggctggc cctgaggcag acaaggaaca ggcgtgggat gacgaggaga acgctggccc
     1141 tgtcctccag tttgactacg aggcacttgc taacaggctg ttcaagctcg ccagtagaca
     1201 gagcacccct tctcagaaca ggaagcgcct ctacaaagtg atccaaaagc tgcgggagct
     1261 ggctggaggc actttcccag aggatgatgt ccctgaaaaa gcctacaaga agatgctgga
     1321 agggaggcgg gaacggaaga agaaaaagaa gcgcttgccc aaacctcagc cccagaataa
     1381 ggaagcgggg agtgaggcag aatcctcaag tgcagaccca ggcccaggaa ggaagaggaa
     1441 gaggaacagg aaaacggatg agaaggctgg ccaagggggt cctcctggga agaggaggaa
     1501 gcccggggct agggcaaagg gggctggggc ccagcaaccc aagaagagga tacagtcatc
     1561 acagagtgca gagtgaggtg cacagcccag gctggcacat ggtggaatgg ggcaggatac
     1621 ctgggcatgc tcctgcagcc tctgaatgcc gaggttctga gcgtccgtcc tataggggag
     1681 gagcaggagg aggacggaag aaactcttgg tttagtccca gcctttaagc atgatcctgc
     1741 ctcagagcca tgacctgcat ctcagaaaaa cactcaacat ttcacttgta catatgctat
     1801 ggctgtgcct gatcctagcc agagaggcca gaagatctgg agactgagtc cagcctgggt
     1861 tgcagagtaa atccctgtct cagcttccct ccaccatagt caggaaaaca aaaccaagta
     1921 actgtgtggt cactgtcccc tccacccttg gctgcccaca aataaactgc gggtccttac
     1981 agcacatggc tgcttctccc atttttgg
//
