LOCUS       NM_011029               1861 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus ribosomal protein SA (Rpsa), mRNA.
ACCESSION   NM_011029
VERSION     NM_011029.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1861)
  AUTHORS   Jiang,Y., Sun,S., Quan,Y., Wang,X., You,Y., Zhang,X., Zhang,Y.,
            Liu,Y., Wang,B., Xu,H. and Cao,X.
  TITLE     Nuclear RPSA senses viral nucleic acids to promote the innate
            inflammatory response
  JOURNAL   Nat Commun 14 (1), 8455 (2023)
   PUBMED   38114488
  REMARK    GeneRIF: Nuclear RPSA senses viral nucleic acids to promote the
            innate inflammatory response.
            Erratum:[Nat Commun. 2024 Jan 29;15(1):855. doi:
            10.1038/s41467-024-45275-2.. PMID: 38287017]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1861)
  AUTHORS   Harada,M. and Akita,K.
  TITLE     Mouse vaginal development with lateral enlargement at late
            embryonic stages and caudal elongation after birth
  JOURNAL   Congenit Anom (Kyoto) 63 (2), 30-39 (2023)
   PUBMED   36517931
REFERENCE   3  (bases 1 to 1861)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   4  (bases 1 to 1861)
  AUTHORS   Mattebo,A., Sen,T., Jassinskaja,M., Pimkova,K., Prieto
            Gonzalez-Albo,I., Alattar,A.G., Ramakrishnan,R., Lang,S., Jaras,M.,
            Hansson,J., Soneji,S., Singbrant,S., van den Akker,E. and
            Flygare,J.
  TITLE     Yippee like 4 (Ypel4) is essential for normal mouse red blood cell
            membrane integrity
  JOURNAL   Sci Rep 11 (1), 15898 (2021)
   PUBMED   34354145
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1861)
  AUTHORS   Fu,M., Barlow-Anacker,A.J., Kuruvilla,K.P., Bowlin,G.L.,
            Seidel,C.W., Trainor,P.A. and Gosain,A.
  TITLE     37/67-laminin receptor facilitates neural crest cell migration
            during enteric nervous system development
  JOURNAL   FASEB J 34 (8), 10931-10947 (2020)
   PUBMED   32592286
REFERENCE   6  (bases 1 to 1861)
  AUTHORS   Douville,P.J. and Carbonetto,S.
  TITLE     Genetic linkage analysis in recombinant inbred mice of P40, a
            putative clone for the high-affinity laminin receptor
  JOURNAL   Mamm Genome 3 (8), 438-446 (1992)
   PUBMED   1353694
REFERENCE   7  (bases 1 to 1861)
  AUTHORS   Castronovo,V., Taraboletti,G. and Sobel,M.E.
  TITLE     Functional domains of the 67-kDa laminin receptor precursor
  JOURNAL   J Biol Chem 266 (30), 20440-20446 (1991)
   PUBMED   1834645
REFERENCE   8  (bases 1 to 1861)
  AUTHORS   Fernandez,M.T., Castronovo,V., Rao,C.N. and Sobel,M.E.
  TITLE     The high affinity murine laminin receptor is a member of a
            multicopy gene family
  JOURNAL   Biochem Biophys Res Commun 175 (1), 84-90 (1991)
   PUBMED   1825600
REFERENCE   9  (bases 1 to 1861)
  AUTHORS   McCaffery,P., Neve,R.L. and Drager,U.C.
  TITLE     A dorso-ventral asymmetry in the embryonic retina defined by
            protein conformation
  JOURNAL   Proc Natl Acad Sci U S A 87 (21), 8570-8574 (1990)
   PUBMED   2146686
REFERENCE   10 (bases 1 to 1861)
  AUTHORS   Rabacchi,S.A., Neve,R.L. and Drager,U.C.
  TITLE     A positional marker for the dorsal embryonic retina is homologous
            to the high-affinity laminin receptor
  JOURNAL   Development 109 (3), 521-531 (1990)
   PUBMED   2144817
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AV586849.1, BC081461.1, AK011043.1 and AK082935.1.
            
            On Mar 14, 2009 this sequence version replaced NM_011029.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK082935.1, AK010985.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                AV586849.1         78-142
            66-1051             BC081461.1         1-986
            1052-1281           AK011043.1         1034-1263
            1282-1861           AK082935.1         1262-1841
FEATURES             Location/Qualifiers
     source          1..1861
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 71.41 cM"
     gene            1..1861
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /note="ribosomal protein SA"
                     /db_xref="GeneID:16785"
                     /db_xref="MGI:MGI:105381"
     exon            1..65
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /inference="alignment:Splign:2.1.0"
     exon            66..231
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..986
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /note="40S ribosomal protein SA; 37LRP; LRP/LR; LBP/p40;
                     OFA/iLRP; 67 kDa laminin receptor; 37 kDa oncofetal
                     antigen; 37/67 kDa laminin receptor; 37 kDa laminin
                     receptor; laminin-binding protein precursor p40; P40-3,
                     functional; P40-8, functional; laminin receptor 1 (67kD,
                     ribosomal protein SA); 67LR"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS2"
                     /protein_id="NP_035159.3"
                     /db_xref="CCDS:CCDS23623.1"
                     /db_xref="GeneID:16785"
                     /db_xref="MGI:MGI:105381"
                     /translation="MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSD
                     GIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGR
                     FTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIA
                     IPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAA
                     EKAVTKEEFQGEWTAPAPEFTAAQPEVADWSEGVQVPSVPIQQFPTEDWSAQPATEDW
                     SAAPTAQATEWVGATTEWS"
     exon            232..350
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /inference="alignment:Splign:2.1.0"
     exon            351..596
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /inference="alignment:Splign:2.1.0"
     exon            597..725
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /inference="alignment:Splign:2.1.0"
     exon            726..891
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1861
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1032..1037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /note="hexamer: AATAAA"
     polyA_site      1065
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /note="major polyA site"
     polyA_site      1122
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
     polyA_site      1158
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
     regulatory      1372..1377
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /note="hexamer: AACAAA"
     polyA_site      1396
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
     regulatory      1831..1836
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
                     /note="hexamer: ATTAAA"
     polyA_site      1859
                     /gene="Rpsa"
                     /gene_synonym="67kDa; 67lr; Lamr; Lamr1; Lamrl1; MLR; P40;
                     P40-3; P40-8"
ORIGIN      
        1 acgtcatttc cggccgcccg tcctttcgcg ctacccgggg acgggtccat acggcgttgt
       61 tcttgattcc catcgtaact taaagggaaa cttacacaat gtccggagcc cttgacgtcc
      121 tgcagatgaa ggaggaggat gtcctcaaat tccttgctgc gggaacccac ttaggtggca
      181 ccaaccttga ctttcagatg gagcagtaca tctacaaaag gaaaagtgac ggtatctaca
      241 tcataaacct gaagaggacc tgggagaagc tgttgctcgc agctcgagct attgttgcca
      301 tcgagaatcc tgctgacgtc agcgtcatct cctccaggaa cactggccag cgagctgtgc
      361 tgaagtttgc tgctgccaca ggagccactc cgatcgctgg ccgcttcaca cctgggacct
      421 tcactaacca gatccaagca gccttcaggg agccacggct tctagtggtg accgatccca
      481 gggctgacca tcagccactc acagaggcct cttatgtcaa cctgcccacc attgctctgt
      541 gtaacacaga ttctcccctg cgctatgtgg acattgccat cccatgcaac aacaagggag
      601 ctcactcagt gggtctgatg tggtggatgc tggccaggga agtactccgc atgcgaggta
      661 ctatctcccg tgagcacccc tgggaggtca tgcctgatct ttacttctac agagacccag
      721 aggagattga gaaggaggag caggctgctg ctgagaaggc tgtgaccaag gaggaattcc
      781 agggtgaatg gaccgcacca gctcctgagt tcactgctgc tcagcctgag gtggccgact
      841 ggtctgaggg tgtgcaggtt ccctctgtgc ccatccagca gttccccacg gaagactgga
      901 gtgcacagcc agccactgag gattggtcag cagctcccac agcgcaggcc actgagtggg
      961 ttggagccac cactgagtgg tcctgagctg ctgtgcaggt gcctgagcaa agggaaaaaa
     1021 gatggaagga aaataaagtt gctaaaagct gtcttatggt cctcactgca gactgtacct
     1081 ggattggcat ttggctatac aacagaggca tggtcctact gacatgtttt gtgttgaata
     1141 cttaagcatg tgaacacatg ggtttttttt ttttttaatg taaaatgtag taacacaatg
     1201 tttaggtggc tttggtgtta gctctggaga cttcatgtgt catctaggtg aggtgttctt
     1261 taacacaggg tctctgttct gtcatgcctc atagatcctt ctacctccag attggagagg
     1321 gaaaaggctt atgtcactga acctggccag attgggattt tgtgtcccag gaacaaagtt
     1381 aatgctaaaa agttaatgcc ttggtgagac tgatagtctg atggtgtgaa ttcacagtaa
     1441 gtggttggga ttgccagatg gaattccctg agctgccgtg acaggtggca ttgcagaagt
     1501 gaaggattca ggaatttgag tgttgggtgg gggcctgtga atagcacttg ggctgggagg
     1561 ggagactgct gcccctgaat gtcctggaat tcaaggacag tacctggtta aatgtttttc
     1621 tagcttttct aaaaagtttg ttaggcctgg cattggcggc gcacaccttt aatcccagca
     1681 cttgggagtc aggcaggtgg atttctggcc tggtctacag agagttccag gatagccagg
     1741 gatacacaga aatcctgcct caggaaaaaa ccaaaaagaa gtttgctaaa aataagcatt
     1801 tttgcttgat ggtattgaag attgtaagac attaaattgt gtcattactt ctccaggtac
     1861 t
//
