LOCUS       NM_001417226             893 bp    mRNA    linear   ROD 17-DEC-2024
DEFINITION  Mus musculus ribosomal protein S5 (Rps5), transcript variant 1,
            mRNA.
ACCESSION   NM_001417226
VERSION     NM_001417226.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 893)
  AUTHORS   Susanto,T.T., Hung,V., Levine,A.G., Chen,Y., Kerr,C.H., Yoo,Y.,
            Oses-Prieto,J.A., Fromm,L., Zhang,Z., Lantz,T.C., Fujii,K.,
            Wernig,M., Burlingame,A.L., Ruggero,D. and Barna,M.
  TITLE     RAPIDASH: Tag-free enrichment of ribosome-associated proteins
            reveals composition dynamics in embryonic tissue, cancer cells, and
            macrophages
  JOURNAL   Mol Cell 84 (18), 3545-3563 (2024)
   PUBMED   39260367
REFERENCE   2  (bases 1 to 893)
  AUTHORS   Yin,D. and Shen,G.
  TITLE     Exosomes from adipose-derived stem cells regulate macrophage
            polarization and accelerate diabetic wound healing via the
            circ-Rps5/miR-124-3p axis
  JOURNAL   Immun Inflamm Dis 12 (6), e1274 (2024)
   PUBMED   38888351
  REMARK    GeneRIF: Exosomes from adipose-derived stem cells regulate
            macrophage polarization and accelerate diabetic wound healing via
            the circ-Rps5/miR-124-3p axis.
REFERENCE   3  (bases 1 to 893)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   4  (bases 1 to 893)
  AUTHORS   Harnett,D., Ambrozkiewicz,M.C., Zinnall,U., Rusanova,A.,
            Borisova,E., Drescher,A.N., Couce-Iglesias,M., Villamil,G.,
            Dannenberg,R., Imami,K., Munster-Wandowski,A., Fauler,B.,
            Mielke,T., Selbach,M., Landthaler,M., Spahn,C.M.T., Tarabykin,V.,
            Ohler,U. and Kraushar,M.L.
  TITLE     A critical period of translational control during brain development
            at codon resolution
  JOURNAL   Nat Struct Mol Biol 29 (12), 1277-1290 (2022)
   PUBMED   36482253
REFERENCE   5  (bases 1 to 893)
  AUTHORS   Zhang,M., Chen,D., Xia,J., Han,W., Cui,X., Neuenkirchen,N.,
            Hermes,G., Sestan,N. and Lin,H.
  TITLE     Post-transcriptional regulation of mouse neurogenesis by Pumilio
            proteins
  JOURNAL   Genes Dev 31 (13), 1354-1369 (2017)
   PUBMED   28794184
REFERENCE   6  (bases 1 to 893)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 893)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
REFERENCE   8  (bases 1 to 893)
  AUTHORS   Pfisterer,P., Ehlermann,J., Hegen,M. and Schorle,H.
  TITLE     A subtractive gene expression screen suggests a role of
            transcription factor AP-2 alpha in control of proliferation and
            differentiation
  JOURNAL   J Biol Chem 277 (8), 6637-6644 (2002)
   PUBMED   11741941
REFERENCE   9  (bases 1 to 893)
  AUTHORS   Vizirianakis,I.S., Pappas,I.S., Gougoumas,D. and Tsiftsoglou,A.S.
  TITLE     Expression of ribosomal protein S5 cloned gene during
            differentiation and apoptosis in murine erythroleukemia (MEL) cells
  JOURNAL   Oncol Res 11 (9), 409-419 (1999)
   PUBMED   10821535
REFERENCE   10 (bases 1 to 893)
  AUTHORS   Vanegas,N., Castaneda,V., Santamaria,D., Hernandez,P.,
            Schvartzman,J.B. and Krimer,D.B.
  TITLE     Cloning, sequencing and expression in MEL cells of a cDNA encoding
            the mouse ribosomal protein S5
  JOURNAL   Biochim Biophys Acta 1357 (1), 1-4 (1997)
   PUBMED   9202169
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC107704.8.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422601.1320517.1,
                                           SRR7652917.391024.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-231               AC107704.8         141288-141518
            232-340             AC107704.8         141943-142051
            341-550             AC107704.8         144362-144571
            551-679             AC107704.8         144707-144835
            680-778             AC107704.8         145366-145464
            779-893             AC107704.8         145542-145656
FEATURES             Location/Qualifiers
     source          1..893
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 7.69 cM"
     gene            1..893
                     /gene="Rps5"
                     /note="ribosomal protein S5"
                     /db_xref="GeneID:20103"
                     /db_xref="MGI:MGI:1097682"
     exon            1..231
                     /gene="Rps5"
                     /inference="alignment:Splign:2.1.0"
     exon            232..340
                     /gene="Rps5"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..847
                     /gene="Rps5"
                     /note="40S ribosomal protein S5; S5 ribosomal protein"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS7"
                     /protein_id="NP_001404155.1"
                     /db_xref="GeneID:20103"
                     /db_xref="MGI:MGI:1097682"
                     /translation="MTEWEAATPAVAETPDIKLFGKWSTDDVQINDISLQDYIAVKEK
                     YAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHL
                     LTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGARE
                     AAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR"
     exon            341..550
                     /gene="Rps5"
                     /inference="alignment:Splign:2.1.0"
     exon            551..679
                     /gene="Rps5"
                     /inference="alignment:Splign:2.1.0"
     exon            680..778
                     /gene="Rps5"
                     /inference="alignment:Splign:2.1.0"
     exon            779..893
                     /gene="Rps5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      865..870
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps5"
                     /note="hexamer: AATAAA"
     polyA_site      893
                     /gene="Rps5"
                     /note="major polyA site"
ORIGIN      
        1 ctcttcctgt ctgtatcagg gcggcgcgtg gtccacgccg agcgactgag aagcccagtc
       61 tgcgccctca ggtgaggctg cggagggaca cggagttcag aagaggtgac catgagtgtt
      121 ctaaggcaca tctggggggc cggaggccga acctgaagcc tgggcgtgac cgcttggatc
      181 tcaccgtttc tctgcgaaaa agggtgccta gggaaactcg gcacgggccg agatgactga
      241 gtgggaagca gccacaccag cggtggcaga gacccctgac atcaagctct ttgggaaatg
      301 gagcactgat gacgtgcaga tcaacgatat ttctctgcag gattacattg ctgtgaagga
      361 gaagtatgcc aagtacctgc cccacagtgc cggacggtat gctgccaagc gcttccgcaa
      421 agcacaatgt cccatcgtgg agcgccttac taactccatg atgatgcatg gtcgtaacaa
      481 cggcaagaag ctcatgactg tgcgaattgt caagcatgcc tttgagatca tccacctgct
      541 cactggtgag aaccctctgc aggtcctggt gaatgctatc atcaacagtg gcccccgaga
      601 agactcaaca cgcattgggc gggccggtac agtgagacga caggctgtgg atgtgtcccc
      661 actgcgtcga gtgaatcagg ccatctggct gctgtgcaca ggggctcgtg aggctgcttt
      721 ccggaacatc aagaccatcg ccgagtgcct tgcagatgag ctcattaatg ctgccaaggg
      781 ctcctccaat tcctatgcca tcaagaagaa agatgaactg gagcgtgtgg ccaagtctaa
      841 ccgctgattt cccagctgct gcctaataaa ctgtgtcctt tggaacaact ata
//
