LOCUS       NM_026147               3641 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ribosomal protein S20 (Rps20), mRNA.
ACCESSION   NM_026147
VERSION     NM_026147.7
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3641)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3641)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   3  (bases 1 to 3641)
  AUTHORS   Liu,Y., Zhao,L.W., Shen,J.L., Fan,H.Y. and Jin,Y.
  TITLE     Maternal DCAF13 Regulates Chromatin Tightness to Contribute to
            Embryonic Development
  JOURNAL   Sci Rep 9 (1), 6278 (2019)
   PUBMED   31000741
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3641)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   5  (bases 1 to 3641)
  AUTHORS   Uslu,V.V., Petretich,M., Ruf,S., Langenfeld,K., Fonseca,N.A.,
            Marioni,J.C. and Spitz,F.
  TITLE     Long-range enhancers regulating Myc expression are required for
            normal facial morphogenesis
  JOURNAL   Nat Genet 46 (7), 753-758 (2014)
   PUBMED   24859337
REFERENCE   6  (bases 1 to 3641)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
REFERENCE   7  (bases 1 to 3641)
  AUTHORS   van der Zwaag,B., Burbach,J.P., Scharfe,C., Oefner,P.J.,
            Brunner,H.G., Padberg,G.W. and van Bokhoven,H.
  TITLE     Identifying new candidate genes for hereditary facial paresis on
            chromosome 3q21-q22 by RNA in situ hybridization in mouse
  JOURNAL   Genomics 86 (1), 55-67 (2005)
   PUBMED   15953540
REFERENCE   8  (bases 1 to 3641)
  AUTHORS   Shu,H., Chen,S., Bi,Q., Mumby,M. and Brekken,D.L.
  TITLE     Identification of phosphoproteins and their phosphorylation sites
            in the WEHI-231 B lymphoma cell line
  JOURNAL   Mol Cell Proteomics 3 (3), 279-286 (2004)
   PUBMED   14729942
REFERENCE   9  (bases 1 to 3641)
  AUTHORS   Fitch,K.R., McGowan,K.A., van Raamsdonk,C.D., Fuchs,H., Lee,D.,
            Puech,A., Herault,Y., Threadgill,D.W., Hrabe de Angelis,M. and
            Barsh,G.S.
  TITLE     Genetics of dark skin in mice
  JOURNAL   Genes Dev 17 (2), 214-228 (2003)
   PUBMED   12533510
REFERENCE   10 (bases 1 to 3641)
  AUTHORS   Hrabe de Angelis,M.H., Flaswinkel,H., Fuchs,H., Rathkolb,B.,
            Soewarto,D., Marschall,S., Heffner,S., Pargent,W., Wuensch,K.,
            Jung,M., Reis,A., Richter,T., Alessandrini,F., Jakob,T., Fuchs,E.,
            Kolb,H., Kremmer,E., Schaeble,K., Rollinski,B., Roscher,A.,
            Peters,C., Meitinger,T., Strom,T., Steckler,T., Holsboer,F.,
            Klopstock,T., Gekeler,F., Schindewolf,C., Jung,T., Avraham,K.,
            Behrendt,H., Ring,J., Zimmer,A., Schughart,K., Pfeffer,K., Wolf,E.
            and Balling,R.
  TITLE     Genome-wide, large-scale production of mutant mice by ENU
            mutagenesis
  JOURNAL   Nat Genet 25 (4), 444-447 (2000)
   PUBMED   10932192
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL807387.10 and AL772401.22.
            
            On Mar 5, 2022 this sequence version replaced NM_026147.6.
            
            Summary: Ribosomes, the organelles that catalyze protein synthesis,
            consist of a small 40S subunit and a large 60S subunit. Together
            these subunits are composed of 4 RNA species and approximately 80
            structurally distinct proteins. This gene encodes a ribosomal
            protein that is a component of the 40S subunit. As is typical for
            genes encoding ribosomal proteins, there are multiple processed
            pseudogenes of this gene dispersed through the genome. [provided by
            RefSeq, Dec 2015].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.277198.1,
                                           SRR13422597.1410643.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               AL807387.10        5739-5855           c
            118-217             AL807387.10        5447-5546           c
            218-291             AL807387.10        5191-5264           c
            292-3229            AL807387.10        2001-4938           c
            3230-3641           AL772401.22        178744-179155       c
FEATURES             Location/Qualifiers
     source          1..3641
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 2.14 cM"
     gene            1..3641
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /note="ribosomal protein S20"
                     /db_xref="GeneID:67427"
                     /db_xref="MGI:MGI:1914677"
     exon            1..117
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..474
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /note="40S ribosomal protein S20"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS10"
                     /protein_id="NP_080423.1"
                     /db_xref="CCDS:CCDS17940.1"
                     /db_xref="GeneID:67427"
                     /db_xref="MGI:MGI:1914677"
                     /translation="MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAK
                     EKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQIT
                     SISIEPGVEVEVTIADA"
     exon            118..217
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /inference="alignment:Splign:2.1.0"
     exon            218..291
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /inference="alignment:Splign:2.1.0"
     exon            292..3641
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      483..488
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /note="hexamer: AATAAA"
     polyA_site      505
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /note="major polyA site"
     regulatory      674..679
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /note="hexamer: ATTAAA"
     polyA_site      696
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
     regulatory      3371..3376
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /note="hexamer: ATTAAA"
     polyA_site      3391
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
     polyA_site      3420
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
     regulatory      3613..3618
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
                     /note="hexamer: AATAAA"
     polyA_site      3641
                     /gene="Rps20"
                     /gene_synonym="4632426K06Rik; Dsk4"
ORIGIN      
        1 cctttctgag ccccggcggt gcgcgctacg gagctcggcc agcctgctcc gtcctgactc
       61 accgctgttc gctcctgctg aggaacaagt cggtcaggaa gccgcgcctc agccatggca
      121 tttaaagata ccggaaagac gcccgtggag cccgaagtgg cgattcaccg aattcgaatc
      181 acgctcacca gccgcaacgt gaagtcgctg gagaaggttt gtgcggactt gatcagaggc
      241 gccaaggaaa agaatctgaa agtgaaagga ccggtgcgca tgcctaccaa gactttgaga
      301 atcactacca gaaaaacacc ttgtggtgaa ggttccaaga cctgggatcg attccagatg
      361 aggatccaca agcgactcat tgatttacat agtccttctg agattgttaa gcagattact
      421 tccatcagta ttgagccggg agttgaggtt gaagtcacca ttgcagatgc ctaagacaac
      481 tgaataaatc gtcttaatgg tcaaattttg ctggcttttg ttcaggtttt ttttttttaa
      541 ttcatgttta tgagtgtaaa tgtgtgtgtc acaggggtgt cagatgttct ttgaaccacc
      601 atgtaggtgc tggaaaccca acctgcatcc tcggagagaa caggttcctt aaccactgag
      661 caagtactga agcattaaac tgcttttaaa aatgaaggtg tgctaacaga ttggtcaggt
      721 gaaaaagaga cgttaggttt cctgcagggg gcgctaagcc aatttaaaga ctaagttggg
      781 ttagaaaaga gcagattgca tccttgatct tttaagcctg gggattttgt tttgttttgg
      841 gatagggtcc caacacagaa caggctgacc tcattaaata tcaatcttat ttgattgcct
      901 ctgctcccag agtactggaa ttaaaggcag ggaccactgt attagccatt ctgagttatt
      961 tgaaatggac tctgcaggcc atacttggtc aaaattctgc cttctcaatt acaggcatga
     1021 gccactatgc ctggtttact tactaataga tgtccaaaga ctagtgtatg aaaattttgc
     1081 ttttccaggt gatttgtgaa aggcagggtg gcctctccca tgtcacacta cttgggttac
     1141 tcatgttgca acatatctgc aactttaggt tgaggggatt tgagcctgca tgtgccactt
     1201 tggccaactg aactaatctt taattccatc taaaactttt aaatctcagt catgtgttca
     1261 actggaaaat aacctagagt gtgctatgtt gacttcaggt acacatcaaa gcaggtttta
     1321 gtgatgtaga agctgtgttt gagttgaact agtgttgagg ctaggcttag gtaccataga
     1381 actttggttt ttcaagacag ggtttctctg tgtagccctg gctgtcctgg aactcactgt
     1441 agaccaggct ggccttgaac tcagaaatct gcctgcctgt gcctcccaac acacccagct
     1501 ctagctttaa attccttgca ccaagagatg ctttatccct ccgctgagaa tacaggtgca
     1561 tgtcagcatg ctaaactcta gataaaattt catcttgttt gaaaggacaa taatataaga
     1621 aaagtgtatt tgcactgtat accatgccct tttgtgttta aagttaaact ggcaacagtg
     1681 tcccatagag gttccagaag aaactgcttc taaggggagg accataaagg gaaatgctta
     1741 ccatagaact ttttaaatgt tcctacaggt tgtactctgg ataggtatat gaacaccttt
     1801 ctattagaac agttttatag tagtacttag tgaatatgta aataatacta tttgtgaaat
     1861 agtttgaggt ttctctatag tcctggctgg cttgagctct ataccagatt ggcttctaaa
     1921 tcagaaatct gcctctatct cctgaatggt tatgatagag atgcaagtta cttaatttct
     1981 tacatgaatt gcactttgta catgcttttg gatatgggcc taggcttttg cttttggatt
     2041 agactgtctt tattacattt actggcttga tactttacag tcttaagccc acttgcctgg
     2101 gtgtgatgca cacctttaat cccagcactt tgggatttct gagttccagg acagccaggg
     2161 ctacgcagag aaaccctgtc ttggagggga aaaaaagaaa ctttggaaat caaaacttct
     2221 tggaaagcca cttttagaga cttgaatcta aggataacta accaggtagt aaccacgagt
     2281 cattgattct gtgaatcttg tatgagtggg ttacaggcag aaattaactt cctctgagag
     2341 cactgctgtt ttagaaatgc gacctagtaa ttaccaaagg cattgaagcc acttgactac
     2401 agtctcaggt ttctgcatct gacattgctg ggactgtgtg gggtttatgg gtgtaaaata
     2461 aaacaggcga aaggatgttg agtggaaagc tttggcttca gaatcaaatt ccaaatcaat
     2521 taccagatca aatcaaatgc cagatcaaat tacaagactt ccttatgact aaattcttca
     2581 gtgacttagg atactaatag tatctgcctc aaaagtgtat gtggttattt ttgtcccagt
     2641 gaagccaaga ttcacatgct atgggcatgg atttcctgag gacatgctag cctatggtat
     2701 gagttacttg aaaggactct gagaaatctt agtccccagc tgtgaggttt ttaaagatca
     2761 tgctcaatgg aaagtggggc agtaatttga gagcatggca caaatgaggt tttatctttt
     2821 gaaactaagt gaatctatgt ccttggacta gcatatttta aatcacacat caaatgaaat
     2881 ttctgttcaa ttcctataaa cagtttattt catattttgt agttaccatt ttcattaaca
     2941 gcatacaccc ttcaattgtg ttgctaaaac tgagtcacat tattctgtaa gaacttactc
     3001 cagtatcaca acttggtgct catccaatat ttttattttc attctatttt ccctgtctag
     3061 ccacgtatgg ccctattctc tcttcttgga ttgaccctag cttcaacaca agaaagcttg
     3121 cagtattttt tttttgcgcc tggttcattg ttttgtcctc aagttctatc catgtgtcca
     3181 gaaattcgag gattttttaa aatttacttt tctgcctaaa tactggtatg tggatagtct
     3241 gttattttta ctgttggttg catatctgta gcatatttct gtatttgcaa tgactacatt
     3301 gaatgtccct tagttaacct cattcttctt aactattttg taggcgtttg ctattcaaag
     3361 cacaatctca attaaaatgt ttttaatagc atctttccac ttggatgtgt aaagaaagta
     3421 tttctagaag tctgaatttt tgttgcattg tagatgtgta cacaataggg ctgggaaagt
     3481 agctcacagt gggtaaaagc catttgttgc caatcctaac agcctgagtt caatcccaga
     3541 atctataagg tagaagaaaa aaaccccagc tcccacaagt tatctggccc tctgcacaca
     3601 tataaatagt gcaataaaaa ttaaccattt aaaaatataa a
//
