LOCUS       NM_008503               1005 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus ribosomal protein S2 (Rps2), mRNA.
ACCESSION   NM_008503
VERSION     NM_008503.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Zengeler,K.E., Shapiro,D.A., Bruch,K.R., Lammert,C.R., Ennerfelt,H.
            and Lukens,J.R.
  TITLE     SSRI treatment modifies the effects of maternal inflammation on in
            utero physiology and offspring neurobiology
  JOURNAL   Brain Behav Immun 108, 80-97 (2023)
   PUBMED   36343752
REFERENCE   2  (bases 1 to 1005)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   3  (bases 1 to 1005)
  AUTHORS   Moore,J., Osinnii,I., Grimm,A., Oettinghaus,B., Eckert,A., Frank,S.
            and Bottger,E.C.
  TITLE     Silencing of the ER and Integrative Stress Responses in the Liver
            of Mice with Error-Prone Translation
  JOURNAL   Cells 10 (11), 2856 (2021)
   PUBMED   34831079
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1005)
  AUTHORS   Moore,J., Akbergenov,R., Nigri,M., Isnard-Petit,P., Grimm,A.,
            Seebeck,P., Restelli,L., Frank,S., Eckert,A., Thiam,K.,
            Wolfer,D.P., Shcherbakov,D. and Bottger,E.C.
  TITLE     Random errors in protein synthesis activate an age-dependent
            program of muscle atrophy in mice
  JOURNAL   Commun Biol 4 (1), 703 (2021)
   PUBMED   34103648
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1005)
  AUTHORS   Lavado,A., Park,J.Y., Pare,J., Finkelstein,D., Pan,H., Xu,B.,
            Fan,Y., Kumar,R.P., Neale,G., Kwak,Y.D., McKinnon,P.J.,
            Johnson,R.L. and Cao,X.
  TITLE     The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and
            Controls Neural Progenitor Number
  JOURNAL   Dev Cell 47 (5), 576-591 (2018)
   PUBMED   30523785
REFERENCE   6  (bases 1 to 1005)
  AUTHORS   Rovai,L.E., Herschman,H.R. and Smith,J.B.
  TITLE     The murine neutrophil-chemoattractant chemokines LIX, KC, and MIP-2
            have distinct induction kinetics, tissue distributions, and
            tissue-specific sensitivities to glucocorticoid regulation in
            endotoxemia
  JOURNAL   J Leukoc Biol 64 (4), 494-502 (1998)
   PUBMED   9766630
REFERENCE   7  (bases 1 to 1005)
  AUTHORS   Chu,C.C. and Paul,W.E.
  TITLE     Expressed genes in interleukin-4 treated B cells identified by cDNA
            representational difference analysis
  JOURNAL   Mol Immunol 35 (8), 487-502 (1998)
   PUBMED   9798653
REFERENCE   8  (bases 1 to 1005)
  AUTHORS   Takenaka,M., Imai,E., Kaneko,T., Ito,T., Moriyama,T., Yamauchi,A.,
            Hori,M., Kawamoto,S. and Okubo,K.
  TITLE     Isolation of genes identified in mouse renal proximal tubule by
            comparing different gene expression profiles
  JOURNAL   Kidney Int 53 (3), 562-572 (1998)
   PUBMED   9507200
REFERENCE   9  (bases 1 to 1005)
  AUTHORS   Derigs,H.G., Reifel-Miller,A., Kaushansky,K., Hromas,R.A. and
            Boswell,H.S.
  TITLE     Granulocyte-macrophage colony-stimulating factor expression is
            regulated at transcriptional and posttranscriptional levels in a
            murine bone marrow stromal cell line
  JOURNAL   Exp Hematol 22 (9), 924-932 (1994)
   PUBMED   8062890
REFERENCE   10 (bases 1 to 1005)
  AUTHORS   Heller,D.L., Gianola,K.M. and Leinwand,L.A.
  TITLE     A highly conserved mouse gene with a propensity to form pseudogenes
            in mammals
  JOURNAL   Mol Cell Biol 8 (7), 2797-2803 (1988)
   PUBMED   3405219
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154566.2, AK166664.1 and BY443672.1.
            
            On Aug 7, 2009 this sequence version replaced NM_008503.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087956.1, AK169119.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                AC154566.2         42989-43058         c
            71-993              AK166664.1         28-950
            994-1005            BY443672.1         421-432
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.51 cM"
     gene            1..1005
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /note="ribosomal protein S2"
                     /db_xref="GeneID:16898"
                     /db_xref="MGI:MGI:105110"
     exon            1..70
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /inference="alignment:Splign:2.1.0"
     exon            71..250
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..955
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /note="repeat family 3; 40S ribosomal protein S2; protein
                     LLRep3; 40S ribosomal protein S4"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS5"
                     /protein_id="NP_032529.2"
                     /db_xref="CCDS:CCDS37493.1"
                     /db_xref="GeneID:16898"
                     /db_xref="MGI:MGI:105110"
                     /translation="MADDAGAAGGPGGPGGPGLGGRGGFRGGFGSGLRGRGRGRGRGR
                     GRGRGARGGKAEDKEWIPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASL
                     KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKL
                     SIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAG
                     IDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKT
                     HTRVSVQRTQAPAVATT"
     exon            251..448
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /inference="alignment:Splign:2.1.0"
     exon            449..782
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /inference="alignment:Splign:2.1.0"
     exon            783..874
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /inference="alignment:Splign:2.1.0"
     exon            875..999
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      974..979
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /note="hexamer: AATAAA"
     polyA_site      999
                     /gene="Rps2"
                     /gene_synonym="Llrep3; S4"
                     /note="major polyA site"
ORIGIN      
        1 cgcgcttctt ggagcactat aaattgtccc ttccgcggcg cctccctctt cttcttcttc
       61 gggagaacac caaatggcgg atgacgccgg tgcagcggga gggcccggag gacccggggg
      121 cccaggatta ggtggccgcg gcggcttccg cggaggattc ggcagcggtc ttaggggccg
      181 tggtcgtggc cgaggccgtg gccgtggtcg aggccgcggg gctcgtggag gtaaagctga
      241 agacaaggag tggatccccg tcaccaagct gggccgtctg gttaaggaca tgaagatcaa
      301 gtccttggag gagatctacc tgttctccct gcccattaag gagtctgaga tcattgattt
      361 cttcctgggt gcgtccctaa aggatgaggt tctgaaaatc atgccagtgc agaagcagac
      421 tcgggctggc cagcggacca ggttcaaggc tttcgtcgct attggggact acaatggtca
      481 cgttggtctt ggtgttaagt gctccaagga ggttgccact gccatccgag gggccatcat
      541 cttggccaag ctttccatcg tccctgtgcg gagaggctac tgggggaaca agattggcaa
      601 gccccacact gttccatgca aggtgacagg ccgctgtggc tctgtgctgg tgcgtctcat
      661 ccctgccccc agaggcactg gcattgtctc tgctcctgtg cccaagaagc tcctgatgat
      721 ggccggtata gatgactgct acacttcagc cagaggctgc actgccaccc tgggcaactt
      781 tgctaaggcc acctttgatg ccatctccaa gacttacagc tacctgactc ccgacctctg
      841 gaaagagact gtcttcacca agtctcctta tcaggaattc acggatcatc ttgtgaaaac
      901 ccacaccaga gtctctgttc agaggaccca ggctccagct gtggctacca cataagggtt
      961 tttatatgag aaaaataaaa gaattaagtc tgctgattaa aaaaa
//
