LOCUS       NM_001360116             744 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus ribosomal protein S19 (Rps19), transcript variant 2,
            mRNA.
ACCESSION   NM_001360116
VERSION     NM_001360116.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (bases 1 to 744)
  AUTHORS   Liu,M., Deng,W., Tang,L., Liu,M., Bao,H., Guo,C., Zhang,C., Lu,J.,
            Wang,H., Lu,Z. and Kong,S.
  TITLE     Menin directs regionalized decidual transformation through
            epigenetically setting PTX3 to balance FGF and BMP signaling
  JOURNAL   Nat Commun 13 (1), 1006 (2022)
   PUBMED   35194044
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 744)
  AUTHORS   Fujii,K., Zhulyn,O., Byeon,G.W., Genuth,N.R., Kerr,C.H., Walsh,E.M.
            and Barna,M.
  TITLE     Controlling tissue patterning by translational regulation of
            signaling transcripts through the core translation factor eIF3c
  JOURNAL   Dev Cell 56 (21), 2928-2937 (2021)
   PUBMED   34752747
REFERENCE   4  (bases 1 to 744)
  AUTHORS   Tiu,G.C., Kerr,C.H., Forester,C.M., Krishnarao,P.S.,
            Rosenblatt,H.D., Raj,N., Lantz,T.C., Zhulyn,O., Bowen,M.E.,
            Shokat,L., Attardi,L.D., Ruggero,D. and Barna,M.
  TITLE     A p53-dependent translational program directs tissue-selective
            phenotypes in a model of ribosomopathies
  JOURNAL   Dev Cell 56 (14), 2089-2102 (2021)
   PUBMED   34242585
REFERENCE   5  (bases 1 to 744)
  AUTHORS   Serin,N., Dihazi,G.H., Tayyeb,A., Lenz,C., Muller,G.A., Zeisberg,M.
            and Dihazi,H.
  TITLE     Calreticulin Deficiency Disturbs Ribosome Biogenesis and Results in
            Retardation in Embryonic Kidney Development
  JOURNAL   Int J Mol Sci 22 (11), 5858 (2021)
   PUBMED   34070742
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 744)
  AUTHORS   Fitch,K.R., McGowan,K.A., van Raamsdonk,C.D., Fuchs,H., Lee,D.,
            Puech,A., Herault,Y., Threadgill,D.W., Hrabe de Angelis,M. and
            Barsh,G.S.
  TITLE     Genetics of dark skin in mice
  JOURNAL   Genes Dev 17 (2), 214-228 (2003)
   PUBMED   12533510
REFERENCE   7  (bases 1 to 744)
  AUTHORS   Da Costa,L., Narla,G., Willig,T.N., Peters,L.L., Parra,M.,
            Fixler,J., Tchernia,G. and Mohandas,N.
  TITLE     Ribosomal protein S19 expression during erythroid differentiation
  JOURNAL   Blood 101 (1), 318-324 (2003)
   PUBMED   12393682
  REMARK    GeneRIF: RPS19 mRNA and protein expression were shown to decrease
            during terminal erythroid differentiation.
REFERENCE   8  (bases 1 to 744)
  AUTHORS   Wang,J., Yang,X., Zhou,P. and Han,H.
  TITLE     Cloning of mouse genomic ribosomal protein L6 gene and analysis of
            its promoter
  JOURNAL   Biochim Biophys Acta 1576 (1-2), 219-224 (2002)
   PUBMED   12031506
REFERENCE   9  (bases 1 to 744)
  AUTHORS   Hrabe de Angelis,M.H., Flaswinkel,H., Fuchs,H., Rathkolb,B.,
            Soewarto,D., Marschall,S., Heffner,S., Pargent,W., Wuensch,K.,
            Jung,M., Reis,A., Richter,T., Alessandrini,F., Jakob,T., Fuchs,E.,
            Kolb,H., Kremmer,E., Schaeble,K., Rollinski,B., Roscher,A.,
            Peters,C., Meitinger,T., Strom,T., Steckler,T., Holsboer,F.,
            Klopstock,T., Gekeler,F., Schindewolf,C., Jung,T., Avraham,K.,
            Behrendt,H., Ring,J., Zimmer,A., Schughart,K., Pfeffer,K., Wolf,E.
            and Balling,R.
  TITLE     Genome-wide, large-scale production of mutant mice by ENU
            mutagenesis
  JOURNAL   Nat Genet 25 (4), 444-447 (2000)
   PUBMED   10932192
REFERENCE   10 (bases 1 to 744)
  AUTHORS   Draptchinskaia,N., Gustavsson,P., Andersson,B., Pettersson,M.,
            Willig,T.N., Dianzani,I., Ball,S., Tchernia,G., Klar,J.,
            Matsson,H., Tentler,D., Mohandas,N., Carlsson,B. and Dahl,N.
  TITLE     The gene encoding ribosomal protein S19 is mutated in
            Diamond-Blackfan anaemia
  JOURNAL   Nat Genet 21 (2), 169-175 (1999)
   PUBMED   9988267
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161441.21.
            
            On Mar 5, 2022 this sequence version replaced NM_001360116.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3835354.121799.1,
                                           SRR13422600.1812439.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-262               AC161441.21        68602-68863         c
            263-333             AC161441.21        68245-68315         c
            334-434             AC161441.21        67899-67999         c
            435-618             AC161441.21        64986-65169         c
            619-673             AC161441.21        64490-64544         c
            674-744             AC161441.21        63640-63710         c
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 13.41 cM"
     gene            1..744
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /note="ribosomal protein S19"
                     /db_xref="GeneID:20085"
                     /db_xref="MGI:MGI:1333780"
     exon            1..262
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /inference="alignment:Splign:2.1.0"
     CDS             230..700
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /note="isoform b is encoded by transcript variant 2; 40S
                     ribosomal protein S19; small ribosomal subunit protein
                     eS19"
                     /codon_start=1
                     /product="small ribosomal subunit protein eS19 isoform b"
                     /protein_id="NP_001347045.1"
                     /db_xref="GeneID:20085"
                     /db_xref="MGI:MGI:1333780"
                     /translation="MPDRRNPGARRMPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEW
                     VDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSH
                     FSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH"
     exon            263..333
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /inference="alignment:Splign:2.1.0"
     exon            334..434
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /inference="alignment:Splign:2.1.0"
     exon            435..618
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /inference="alignment:Splign:2.1.0"
     exon            619..673
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /inference="alignment:Splign:2.1.0"
     exon            674..744
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      719..724
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /note="hexamer: AATAAA"
     polyA_site      744
                     /gene="Rps19"
                     /gene_synonym="Dsk3"
                     /note="major polyA site"
ORIGIN      
        1 gcgagactcg acgcccgact tgtgcgcccg ggaaaccccg tcgttccctt tcccctggct
       61 ggcagcgcgg aggccgcacg gtgagtgagg gctctgggtc gcggctgtgc gcggggccac
      121 ggggccgggc tttctggccc caagagctcg tgccgggacc gcgggaagcc cggcgcgggg
      181 tcgctccgcc ctctggagcc gcggccacgt gcgagcggca ggcccggaca tgcctgatcg
      241 ccgcaatccg ggagcccgga ggatgcccgg agttactgta aaagacgtta accagcagga
      301 gttcgtcaga gctctggcag ccttcctcaa aaagtccggg aagctgaaag tccccgaatg
      361 ggtggacaca gtcaagctgg ccaaacataa agagcttgcc ccatatgatg agaactggtt
      421 ctacacacga gctgcttcca cagcacggca cctgtacctc cgaggtggtg ctggggttgg
      481 ttccatgacc aagatctatg gaggacggca gagaaacggt gtcagaccca gccatttcag
      541 cagaggctct aagagtgtgg cccgccgggt cctccaagcc ctggaggggc tgaaaatggt
      601 ggaaaaggac caagatgggg gccgcaagct gacgcctcag ggacagagag acctggacag
      661 gatcgctgga caggtggcag ctgccaacaa gaagcattag aacaaaggat gctgggttaa
      721 taaattgcct cattcataat cctg
//
