LOCUS       NM_170669               5158 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus ribosomal protein S15A (Rps15a), mRNA.
ACCESSION   NM_170669
VERSION     NM_170669.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5158)
  AUTHORS   Yu,H.Q., Li,F., Xiong,H., Fang,L., Zhang,J., Bie,P. and Xie,C.M.
  TITLE     Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3 activation
            to drive HCC
  JOURNAL   Hepatol Commun 7 (7), e00198 (2023)
   PUBMED   37378633
  REMARK    GeneRIF: Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3
            activation to drive HCC.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5158)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   3  (bases 1 to 5158)
  AUTHORS   Choo,H.J., Cutler,A., Rother,F., Bader,M. and Pavlath,G.K.
  TITLE     Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and
            Survival by Modulating Nuclear Import
  JOURNAL   Stem Cells 34 (11), 2784-2797 (2016)
   PUBMED   27434733
REFERENCE   4  (bases 1 to 5158)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5158)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   6  (bases 1 to 5158)
  AUTHORS   Distler,U., Schmeisser,M.J., Pelosi,A., Reim,D., Kuharev,J.,
            Weiczner,R., Baumgart,J., Boeckers,T.M., Nitsch,R., Vogt,J. and
            Tenzer,S.
  TITLE     In-depth protein profiling of the postsynaptic density from mouse
            hippocampus using data-independent acquisition proteomics
  JOURNAL   Proteomics 14 (21-22), 2607-2613 (2014)
   PUBMED   25211037
REFERENCE   7  (bases 1 to 5158)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
REFERENCE   8  (bases 1 to 5158)
  AUTHORS   Matsumoto,K., Ebihara,K., Yamamoto,H., Tabuchi,H., Fukunaga,K.,
            Yasunami,M., Ohkubo,H., Shichiri,M. and Miyamoto,E.
  TITLE     Cloning from insulinoma cells of synapsin I associated with insulin
            secretory granules
  JOURNAL   J Biol Chem 274 (4), 2053-2059 (1999)
   PUBMED   9890964
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC054792.1.
            
            On Apr 11, 2004 this sequence version replaced NM_170669.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC054792.1, AK032522.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN02415134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5158
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 63.44 cM"
     gene            1..5158
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /note="ribosomal protein S15A"
                     /db_xref="GeneID:267019"
                     /db_xref="MGI:MGI:2389091"
     exon            1..12
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            13..150
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..410
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /EC_number="3.6.5.3"
                     /note="40S ribosomal protein S15a"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS8"
                     /protein_id="NP_733769.1"
                     /db_xref="CCDS:CCDS21768.1"
                     /db_xref="GeneID:267019"
                     /db_xref="MGI:MGI:2389091"
                     /translation="MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKH
                     GYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFI
                     VLTTSAGIMDHEEARRKHTGGKILGFFF"
     exon            151..230
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            231..316
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            317..5136
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      423..428
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      446
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /note="major polyA site"
     regulatory      3977..3982
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3997
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
     regulatory      5116..5121
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5136
                     /gene="Rps15a"
                     /gene_synonym="A630031B11Rik"
ORIGIN      
        1 cttccctcgc cgccaccatg gtgcgaatga atgttctggc ggatgctctc aagagcatca
       61 acaacgctga gaagagaggc aaacgccagg tcctcatcag gccatgttct aaagtcatcg
      121 ttcggttctt aaccgtgatg atgaagcacg gatacattgg tgaatttgag atcattgatg
      181 atcacagagc tgggaagatt gttgtgaacc tcacaggaag gttgaacaag tgtggcgtta
      241 taagccctag atttgatgtt caactcaaag acctagagaa atggcagaac aacctgctcc
      301 cttcacgtca gtttggcttc attgtgctga caacctcggc tggcattatg gaccatgaag
      361 aggcaagacg aaaacataca ggagggaaaa tcctgggatt ctttttttaa acgtaaagca
      421 taaataaaaa gcctttgtgg actgtgctca gggtcagtcc ttttgaatct ctgcagcaga
      481 gtagctggct gtgctgactg gtgacacttc tggtgatgct cagctgtgag gttttatgta
      541 gatattgaaa gcatgaccat tgtcttcact tcacctccag cttgggttgt atgccagtaa
      601 catcagcata aggtggttaa tgacaggatg gtcccttgag tgtgcagtga gtctggttta
      661 tttgccaatg agaagcacag gcctcctgta tgggtctttg cctacagccc cctttcatca
      721 cccagacttg gtagacttac attctgtcac actgttggct cttaatctca gccctgaaaa
      781 atgccatttc ttgggtatca aggctagtct agattcagaa accatataaa ggttgacagc
      841 tggtttaaaa aaaaaaaggc ttggagcttg agttgggttc gcaggttatt ccagggtatc
      901 tgtctgcact ttgtctccca gatttaaagg taagtgccac catgcctagc atggtgactt
      961 attagctttg ttgctgtgga acatacatca aatgaaacat tggtatggct ctggtttcac
     1021 tgtccatggt tagtatctgg tgggtggaca cctggtggaa ccaagctgct catcccagaa
     1081 ctaaggagcc attccccaga gacttgtctt cctactaagt tccatcccta cagcttctag
     1141 tagtagcttc agaggttgtg aattgtggac ttagtctgcc ataacattta aaataggtat
     1201 taaattcaag tcatttggtc actcagcacc cacgtggctc ttcagaacaa cagaagcccc
     1261 tcggacttgt ctgttggaaa aaccagtttg aaataatgta cctgctttag ttgagaaaac
     1321 gctacaactg gtgctgtgtc ctgccatgct gatgagctct gctctgcgac ctgccgaact
     1381 tgggggatct ctacccccag actttgctca gatctgttga tgatttgtcc atgcaggaaa
     1441 gtttacaagg tctctgtgtg tctactactt actagttgct gtgacaaaaa tactgaaagt
     1501 gtttactgtg tgtgaggcac aaagtttgtg ggaagctgta ccctccctca ttttggtgct
     1561 gctcctgcct tgactgacag gatgagctgc cccaaccatc gttgccatct tccataagaa
     1621 gcaggtggct ctattgagtt ccctggaggt gatcccaagg gaaggaggag cctgggaaag
     1681 tggatctcaa gtcccctagt ctggcagttg gctgtttagg aaagtccagt gtcagtgttt
     1741 gatatgttgt aaggaaacaa attcagtttt atttagctta ttggctctgg ggaaatggca
     1801 gttcccatta attggtgctg tctttctctt tgaggatcaa aattagcttc ctgttcagtt
     1861 gttaagcata tttcatagtc aaataatcct cttatcttta caagtgaggt tttccttcga
     1921 gtggatatca gagtccctcc cacggcttct atccctccta tccttgtgta ggaagttaag
     1981 cttgctcatt tgtagattag tggtcggtta cactgcaatt tagagtatca tgtgtactct
     2041 acacatgatt gattctaagc ccccttccct ttccatgtcc ttcaaaaatt tttttattct
     2101 gagacagtgt taggattttt cctgggctag ccaaatgcaa gaagtgttgg tcccagactt
     2161 gtaatctttc tgccttagcc tcccaaattc taggattata gatttatgtc atgtgatgag
     2221 tggtctttta aagattatct tttatttttt ttgagatggg gtttttctgt gtagttttgg
     2281 ctttcttggg acttgctctg tagacccagg atggtcttta ctcagatctg cttgcctctg
     2341 cctcccaact gctaggatta aagcatgagc ctgagccttc atgcctggct gacaggtgaa
     2401 ttctcaatac ctacctagcc atagggaaag tgattgtgtc cccttcctca tagaggggca
     2461 tagtcaccca ggccatacct ttagcttggg cttttggtca gtgaagaagt atgaagggac
     2521 aagaacacta tcaagagcct aatgtgctct ggcctggatg gtcagcacaa aatgaataga
     2581 cttaccaaat tctgctgtct ccttggtaga tgtgaagttg ttggaagagt cctaaattta
     2641 gcagactata ctgtcagcct atcagactat aggctgccgg agggcaagtc tgctacctat
     2701 ttccatctca tgcctgcatt gttcatcccc ctatgtaacc cacctacctg tcactcattc
     2761 ctccatccaa aaactattgt aggttcagtg gaaatttcaa gcttgcctgt ctcagcatct
     2821 ttcttacctt acccctaagg atggcatctc tcttggctac atctttggtt tatctggaga
     2881 tccttgatta atttgaacaa gagctacctt gggttatgca gtttatgcct ccagtgtccc
     2941 agagaccggc atttgagaga tccctgatag caaacccata gggtggcctt tttttcatcc
     3001 accccattct ccctcccacc tccctctttt gaccttgagt cctcaccaga gagaaaccag
     3061 gcccacttaa ttagttctac atgtgtacac tacatgggtg cagtgcccaa gcaggagagg
     3121 tgttagattc ccttttaact atagttaata gacagttttt aagccccagt ggatgctggg
     3181 aagcaaacct acatcctcta gaagagcagc tatttctctg agccatttct ccagcaccat
     3241 tttcccctct tttaaaagca ggtcttgcag tgtggcctag tctggccccc tgaggtgttt
     3301 gcattgcatg gcaggcatgt ccacaggaac accatagttc tcaccactcg tacagcacag
     3361 caagtggggt gccgcagggg attatcactt gagtataaaa taagggttgc tttagattga
     3421 ataggataac cacgcgttct cagaacaatc aaggaaggct ggggtgagcc agcaccgacc
     3481 ttaattgttt acttagtaaa ctactaaatg tatgcacgtg taagcttttg ccttgattga
     3541 ggtcaagctg tcgagaaatg gttctcttta cagtggatcc agtcaggatt ggcagcaagc
     3601 acctttgcct gctgagccta catgttgtat agaatggcaa cgttgtgtag aatggcagta
     3661 cattaaatgg gtttttcatt tacgaagtgt gctggctggt tttgtgtcaa cttgacacaa
     3721 gctggagttc agttgaggaa atgcctccat gagattcagc agttttctca gtgatggggg
     3781 gatgggggct agccccttgt gggtggtgcc atctctgggc tggtaattct gggttctgta
     3841 agcaagctga acaagccagg ggaagcaagc cagtaacatt cctccatggc ctctgcatca
     3901 gctcctgctt cctgacctgc ttgagttcca gccctgactt ccttggggat gaacagcagt
     3961 gtggaagtgt taactgaata aaccctttcc tccccaactt gcttcgtggt catgttttgt
     4021 gtaggaatag aaactctgac ttaagacata atggttttga gattatggtt ttatttatga
     4081 ctatggtgag ccctactgaa gaagcctcag cattcagatc tatcgtatcc tgccagttgc
     4141 ttgaagcatg aatttgagtg tcccttctaa ataggttttc atttctgtga aatgggtaca
     4201 aagaggctat gttctagtac tgtggtcagg cttgggataa actgtaaaat gaaagtggtg
     4261 cttggcataa cactatttta cttgttttta atcctgagag ggagtctgaa tgcttctggg
     4321 aagaagatgt ggagtccgga ctgacctgtc ctgactatag tatgtctgca gtcctaataa
     4381 cagcccctgg ggggttcttc actcttctca gcttttgtac tcagagtgat gggggctagt
     4441 gaggctgcca tgtgggaaat ctaataacca ggggtattgg gaaaattgag atccttttct
     4501 gtagatgatg aatgagggca aagagaagca gtaagtattt ggggcctgaa gcagagagat
     4561 gaggggaagg gaagttataa tggaagtctt gagtcagctg acaggaatca tgagtcagca
     4621 gaaacctgag tgaccaggag ttgtgagtca gcagaaagta tagatagcaa agatgatgag
     4681 tcaccatcat tcttggtgaa tcagggctga actgttgtta ctgaaattcc tttttgggtt
     4741 cttggtctta tcaatgagat aatttagggg ctgggacaat ggctaggttg ttaagagcac
     4801 ttgctgctcc tgagtggatt caggttcggt ccccagcacc tccgtcgggc tgctcacact
     4861 agcctatgac ttgggctccg gggagtctga caccctcctc tggccttcaa gtgtgcttgt
     4921 acacgcctgg gggtggggtg gggggagatg gagtaatgaa atgaaatttc tgatttttta
     4981 agtctttgaa agtaaaatac aattatgttg gcctctctcc ctgtcctttt cattcaacct
     5041 ctcctatgtg ctctcctctt actcaatttc tcgaatttat ggcctctctt tgtgcgaaca
     5101 tgtgtgtgtg aataaaataa agcatttttt ttaaaaaaaa aaaaaaaaaa aaaaaaaa
//
