LOCUS       NM_009091                522 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus ribosomal protein S15 (Rps15), transcript variant 1,
            mRNA.
ACCESSION   NM_009091
VERSION     NM_009091.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 522)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (bases 1 to 522)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   3  (bases 1 to 522)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
REFERENCE   4  (bases 1 to 522)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   5  (bases 1 to 522)
  AUTHORS   Huang,N., Negi,S., Szebeni,A. and Olson,M.O.
  TITLE     Protein NPM3 interacts with the multifunctional nucleolar protein
            B23/nucleophosmin and inhibits ribosome biogenesis
  JOURNAL   J Biol Chem 280 (7), 5496-5502 (2005)
   PUBMED   15596447
REFERENCE   6  (bases 1 to 522)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
REFERENCE   7  (bases 1 to 522)
  AUTHORS   Takenaka,M., Imai,E., Kaneko,T., Ito,T., Moriyama,T., Yamauchi,A.,
            Hori,M., Kawamoto,S. and Okubo,K.
  TITLE     Isolation of genes identified in mouse renal proximal tubule by
            comparing different gene expression profiles
  JOURNAL   Kidney Int 53 (3), 562-572 (1998)
   PUBMED   9507200
REFERENCE   8  (bases 1 to 522)
  AUTHORS   Taylor,K.D. and Piko,L.
  TITLE     Expression of ribosomal protein genes in mouse oocytes and early
            embryos
  JOURNAL   Mol Reprod Dev 31 (3), 182-188 (1992)
   PUBMED   1554502
REFERENCE   9  (bases 1 to 522)
  AUTHORS   Taylor,K.D. and Piko,L.
  TITLE     Expression of the rig gene in mouse oocytes and early embryos
  JOURNAL   Mol Reprod Dev 28 (4), 319-324 (1991)
   PUBMED   2064774
REFERENCE   10 (bases 1 to 522)
  AUTHORS   Sugawara,A., Nata,K., Inoue,C., Takasawa,S., Yamamoto,H. and
            Okamoto,H.
  TITLE     Nucleotide sequence determination of mouse, chicken and Xenopus
            laevis rig cDNAs: the rig-encoded protein is extremely conserved
            during vertebrate evolution
  JOURNAL   Biochem Biophys Res Commun 166 (3), 1501-1507 (1990)
   PUBMED   2154983
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AV569793.1 and AA027738.1.
            
            On Aug 4, 2009 this sequence version replaced NM_009091.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AV569793.1, BU530301.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-511               AV569793.1         1-511
            512-522             AA027738.1         439-449
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..522
                     /gene="Rps15"
                     /gene_synonym="rig"
                     /note="ribosomal protein S15"
                     /db_xref="GeneID:20054"
                     /db_xref="MGI:MGI:98117"
     exon            1..53
                     /gene="Rps15"
                     /gene_synonym="rig"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..488
                     /gene="Rps15"
                     /gene_synonym="rig"
                     /note="isoform 1 is encoded by transcript variant 1; 40S
                     ribosomal protein S15; small ribosomal subunit protein
                     uS19"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS19 isoform 1"
                     /protein_id="NP_033117.1"
                     /db_xref="CCDS:CCDS35978.1"
                     /db_xref="GeneID:20054"
                     /db_xref="MGI:MGI:98117"
                     /translation="MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRR
                     LNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTF
                     NQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK"
     exon            54..139
                     /gene="Rps15"
                     /gene_synonym="rig"
                     /inference="alignment:Splign:2.1.0"
     exon            140..374
                     /gene="Rps15"
                     /gene_synonym="rig"
                     /inference="alignment:Splign:2.1.0"
     exon            375..522
                     /gene="Rps15"
                     /gene_synonym="rig"
                     /inference="alignment:Splign:2.1.0"
     regulatory      497..502
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rps15"
                     /gene_synonym="rig"
                     /note="hexamer: AATAAA"
     polyA_site      522
                     /gene="Rps15"
                     /gene_synonym="rig"
                     /note="major polyA site"
ORIGIN      
        1 gataactgcg caagcgcagc ccgtacttcc ttttccgagt aaccgccaag atggccgaag
       61 tggagcagaa gaagaagcgc accttccgca agttcaccta ccgtggcgta gacctcgacc
      121 aactgctcga catgtcctat gagcaactga tgcagctgta cagcgcccgc cagaggaggc
      181 gcctgaaccg tggtcttcgg cggaagcaac actcactgct caagcgcttg agaaaggcca
      241 aaaaggaggc accacccatg gagaagcctg aggtggtgaa gacgcacctg agggacatga
      301 tcatcctgcc ggagatggtg ggtagcatgg tgggcgtgta caacggcaag accttcaacc
      361 aggtggagat caaaccagag atgatcggcc actacctggg cgagttctcc atcacctaca
      421 aacccgtgaa gcacggccgg cccgggatcg gtgccaccca ctcctcccga ttcatccccc
      481 tcaagtagcc gaggccaata aagactggtt ttggtccctg ga
//
