LOCUS       NM_001081293            8419 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus regulation of nuclear pre-mRNA domain containing 2
            (Rprd2), transcript variant 1, mRNA.
ACCESSION   NM_001081293 XM_887327
VERSION     NM_001081293.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8419)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8419)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8419)
  AUTHORS   Dietrich,J.E., Panavaite,L., Gunther,S., Wennekamp,S., Groner,A.C.,
            Pigge,A., Salvenmoser,S., Trono,D., Hufnagel,L. and Hiiragi,T.
  TITLE     Venus trap in the mouse embryo reveals distinct molecular dynamics
            underlying specification of first embryonic lineages
  JOURNAL   EMBO Rep 16 (8), 1005-1021 (2015)
   PUBMED   26142281
REFERENCE   4  (bases 1 to 8419)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   5  (bases 1 to 8419)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093317.22 and BC067054.1.
            
            On Jan 19, 2019 this sequence version replaced NM_001081293.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC067054.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN01164134,
                                           SAMN01164142 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-195               AC093317.22        52511-52705
            196-4735            BC067054.1         1-4540
            4736-6644           BC067054.1         4543-6451
            6645-8419           AC093317.22        109817-111591
FEATURES             Location/Qualifiers
     source          1..8419
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.0 cM"
     gene            1..8419
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /note="regulation of nuclear pre-mRNA domain containing 2"
                     /db_xref="GeneID:75137"
                     /db_xref="MGI:MGI:1922387"
     exon            1..407
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..4612
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /note="isoform 1 is encoded by transcript variant 1;
                     regulation of nuclear pre-mRNA domain-containing protein
                     2"
                     /codon_start=1
                     /product="regulation of nuclear pre-mRNA domain-containing
                     protein 2 isoform 1"
                     /protein_id="NP_001074762.1"
                     /db_xref="CCDS:CCDS38549.1"
                     /db_xref="GeneID:75137"
                     /db_xref="MGI:MGI:1922387"
                     /translation="MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGL
                     SSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFAD
                     VLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEDMIVALREALMDRAASHNARLQKLQ
                     CFPGTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLMY
                     KRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLD
                     KQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDP
                     EESPVPSPSMDAPSPTGSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDVEDMELS
                     DVEDDGSKIIVEDRKEKPVEKPAVSTGVPTKSTESVSKASPCAPPSVPTTAAPPLPKP
                     LSTALLSPSPTLVLPNLANVDLAKISSILSSLTSVMKNTGVSSASRPSPGIPTSPSNL
                     SSGLKTPAPATTPSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
                     ANPVPASEVTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTS
                     ASKASVGQSPVLPSTTFKLPSSSLGFTGTHNPSPAAPPTEVAVCQSSEVSKPKPESES
                     TSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSEGHASDFQRGPTSTSVDSID
                     GTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYP
                     QELPNSVSTYRPFGLGSDSPYKQPSGGVERPSSLMDSSQEKLFPDTSFQEDEDYRDFE
                     YSGPPPSAMMNLEKKPAKSILKSSKLSDATEYQPILSSYNHRAQEFGVKSAFPPSVRA
                     LLDSSENCDRLSSPPGLFGAFNIRGNEPGSERSPSPSKNDAFFTPDSNHSGLSQSTAG
                     HLTLPQTQYPDSPHSVPHRSIFSSQSTLAAPAGHPPTSGVEKVLASTISTTSTIEFKN
                     MLKNASRKPSDDKHFGQTPNKGTSSDGVSLSNLTQPSLPTTDQQQEEHYRIETRVSSS
                     CLDLPDSTEEKGAPIETLGYHNAANRRMSGEPIKTVESIRVPGKGNRGHGREVSRVGW
                     FDLSTPGSSFDNGPSSASELASLGGGGSGGLTGFKTTPYKERAPQFQESVTSFRSNSF
                     NSTFEHHLPPSPLEHGAPFQREPVGPSSAPPAPPKDHGGIFSREAPTHLPSVDLSNPF
                     TKEASLAHAGPPPPPGEHSGVPFPPPPPPPPPGELSSGGTGVPFATPAPPPPPVDHSG
                     VVPFPTPPLPEHGVTGAVSVFPKDHSSLLQGTMAEHFGVLTGPRDLNGPGLNRSRESL
                     SLPSHPLEHLGPALGGGGGGNTSSSGLPLSPAHRDAIGRSGMILRSPRPDFRPREAFL
                     GRDPFHSLKRPRPPFVRGPPFFAPKRPFFPPRY"
     exon            408..537
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            538..638
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            639..770
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            771..823
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            824..950
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1126
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1409
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..1670
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            1671..1871
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..8419
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4988..4993
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /note="hexamer: AATAAA"
     polyA_site      5013
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /note="major polyA site"
     regulatory      7927..7932
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /note="hexamer: AATAAA"
     polyA_site      7947
                     /gene="Rprd2"
                     /gene_synonym="2810036A19Rik; 4930535B03Rik;
                     6720469I21Rik; mKIAA0460"
                     /note="major polyA site"
ORIGIN      
        1 cgcagcgtgt gggagccgcc agcgcgccca gcagctagcc ctcctgccgc cagaggagcc
       61 tagcgcgtgc agcgtcccca ccccctggcc gccctcccct cctgctgctt tcacgcactc
      121 gcactgattg ttttgcccgc tcccgccgcc gccgccgccg ccgccgccag aggaccagag
      181 gcgcttgtgc aaaccgggga agatggcggc cggcggcggc ggaggcagca gtaaggcctc
      241 ctcctcgtcg gcctcgtccg caggggccct ggagtcttcg ttggatcgaa aattccagtc
      301 ggtgaccaac accatggaat ccattcaagg cttgtcgtcc tggtgtatag aaaacaagaa
      361 acaccacagt acaatcgtct accattggat gaagtggctc cggagatcta catatcccca
      421 tcgtttgaat ctcttttatc ttgccaatga tgtcatacag aattgtaaac ggaaaaatgc
      481 aatcatattt cgtgaatcat ttgctgatgt gcttcctgaa gcagctgctc tagtgaagga
      541 tccatccgtc tctaagtcta tagaacgaat ctttaaaatc tgggaagatc gaaatgtgta
      601 cccagaagac atgattgtgg cattgagaga agctttaatg gacagagcag cttcccataa
      661 tgccagactg caaaaactgc aatgttttcc aggtaccact ttcaaaactc agaagcagct
      721 gaaagaaaat ctgaacaaac aaccgaataa gcagtggaag aaatcacaaa catccacgaa
      781 tccaaaagct gctctcaaat ctaagattgt tgctgagttt cgatctcagg ccctcattga
      841 agagttgctg atgtacaaac gatcagaaga tcagatagaa ctgaaggaga aacagttgtc
      901 aactatgaga gtggatgtct gcagcacaga aactctcaag tgtttaaaag ataaaacagg
      961 tggaaagaag ttctccaaag aatttgaaga agcaagttcc aagctagagg agtttgtgaa
     1021 tggattagat aaacaggtga aaaatgggcc ctcactaaca gaagcattag agaacgctgg
     1081 aattttctat gaagcacagt acaaggaagt gaaagtggtc gctaacgctt acaaaacctt
     1141 cgctaaccga gtaaacaact taaagaagaa gttggatcaa ttgaagtcaa cccttcctga
     1201 tcctgaggaa tcaccagtcc cctctccaag tatggatgct ccttccccaa ctggttctga
     1261 gtctccattc cagggcatgg gaggtgaaga accccagtca ccggccatgg agagtgacaa
     1321 gtctgccaca cccgagcctg tgactgataa ccgtgatgtg gaagacatgg aactctcaga
     1381 tgtggaagat gatggatcaa aaatcattgt ggaggaccgg aaagaaaagc ctgtggagaa
     1441 acctgctgtc tccactggtg tgcccaccaa gtcaacagaa agtgtctcga aagcctcacc
     1501 gtgtgcccca ccgtctgtgc ccacgacggc agctccacct ctcccgaagc ctctgagcac
     1561 tgcacttctg tccccttccc caactttggt tttgccaaac ctggcaaatg tggatctggc
     1621 aaagatcagt tccatcctta gcagcctaac atcagtcatg aaaaatacgg gggtcagttc
     1681 tgcatcaaga ccttctccag gaattcctac cagtcccagc aacctcagca gtggcctgaa
     1741 aacacctgca cctgccacaa caccatctca caaccctctg gcaaatatcc tgtcaaaggt
     1801 ggagatcacc ccagagagca ttctctctgc tctttctaaa acccagacac agtcagcccc
     1861 tgcactccaa ggcttgtcat cattacttca gagtgttact gcgaaccctg tgccagccag
     1921 tgaagtcact tcccagagca ccacagcctc ccctgcgagc accacaggct ctgccgtaaa
     1981 ggggagaaat ctactctcca gtacccagtc ttttattccc aaaagcttca actattctcc
     2041 tagttcttca acttctgaag tctcttccac ttcagcaagc aaggcgtcag ttgggcagag
     2101 cccggtgctc ccaagcacta cgtttaaact accatccagt tctttgggat ttactggtac
     2161 ccacaatcct agccctgctg ccccacctac tgaagttgcc gtgtgccaat cctcagaggt
     2221 ctccaagcca aagccagaat cagagtccac ctctccaagc ctggaaatga agatccacaa
     2281 cttcttgaaa ggtaatcctg gtttcagtgg cttaaactta aacatcccga tcctaagcag
     2341 cttgggatcc agtgccccat cagagggcca tgcctcagac ttccagcgtg gtcctactag
     2401 cacttcagtt gacagcatcg atggaactcc tgttcgggat gaacggagtg ggacacccac
     2461 ccaggatgag atgatggata agcccacatc cagcagcgta gacactatgt ccctgctgtc
     2521 taagatcatc agccctggtt cctcaacacc cagcagtaca aggtcgccac ctccaggaag
     2581 agatgaaagc tacccccaag agctccccaa ttctgtgtct acatatcgac cgtttggtct
     2641 gggcagtgac tctccctaca agcagccttc tggtggagtt gagaggccgt catcactgat
     2701 ggactcttca caggaaaagc tcttcccaga tacttccttc caggaagacg aggactaccg
     2761 agattttgag tattcagggc ctcctccatc tgccatgatg aatctagaga agaaaccagc
     2821 caaatccatc ctgaagtcaa gcaagctttc tgatgccact gagtaccagc caatcctgtc
     2881 tagttacaac cacagggccc aagagtttgg ggtcaagtct gccttccctc catctgtaag
     2941 ggccctcctg gactctagtg agaactgtga ccgtctctca tctccccctg ggctatttgg
     3001 tgccttcaac ataagaggga atgaacctgg gtctgagcgg tcaccatcac caagtaaaaa
     3061 tgatgcattt ttcacccctg actccaacca cagtggcttg tctcagtcta ctgctgggca
     3121 tctcacgttg ccacagacac aatacccaga ctctcctcac tcagtcccac atcgttccat
     3181 tttctcttca cagagtaccc ttgccgctcc agcaggccac ccacccacat caggcgtgga
     3241 aaaagtcctg gcctccacga tttccaccac atcgacgatt gagtttaaga atatgcttaa
     3301 aaacgcctca cgcaagccct cagatgataa gcattttggc cagacaccca acaagggtac
     3361 ttcaagtgat ggtgtcagtc tctcaaacct cacccagccc agcttgccca ccactgacca
     3421 acaacaggaa gaacactatc gaatagaaac tcgtgtttcc tcctcctgtt tagacttgcc
     3481 tgacagcaca gaagaaaagg gggcccctat agaaactcta ggttatcata acgcagctaa
     3541 taggaggatg tcaggggagc cgataaagac tgtagagtct atacgagttc ctgggaaggg
     3601 aaatagagga catgggcgcg aggtttcaag agtgggttgg tttgatctga gcacaccagg
     3661 cagctctttt gacaatggtc cctcaagtgc ctctgagttg gcatcccttg ggggtggggg
     3721 cagcggaggc ctcactggct ttaagacaac gccgtacaag gaacgggcac cccagtttca
     3781 ggagagtgtc accagctttc gttccaacag tttcaactca acatttgagc atcatctccc
     3841 cccatcccct ttggaacatg gggcaccctt ccagagagag ccagtggggc cgtcatctgc
     3901 cccacctgcc cctcctaagg atcatggtgg tatcttctct cgagaggcac ccactcatct
     3961 gccctctgtg gatctttcga acccctttac aaaggaggca tctctggccc acgctggccc
     4021 accacctcct ccaggagagc acagcggagt tcctttccct ccaccccccc ctcctccacc
     4081 cccgggggaa cttagcagtg gagggactgg tgtccccttt gctactccag ccccgcctcc
     4141 accccctgtt gaccactctg gggttgtacc tttcccaact ccaccactgc cagagcatgg
     4201 agtaactggg gctgtgtcag tttttcccaa ggaccatagt tccctccttc aagggaccat
     4261 ggctgagcat tttggggtgc tcacaggacc cagggacctc aatggccctg gtcttaaccg
     4321 ttcacgagag agcctgagcc tgccttccca tcctctggag cacctgggcc cagcccttgg
     4381 aggaggtggg ggaggcaaca ccagcagcag tggccttccc ttgagtcccg cacacagaga
     4441 cgccatcggc cggagtggta tgattttacg gagtccccgg ccagactttc ggcctaggga
     4501 agcttttctc ggcagagacc cattccacag tttaaagaga cccaggccac cttttgttag
     4561 aggccctccg ttctttgcac caaaacgccc attcttccct cccaggtact gatggaaatc
     4621 tggggaaggc attttgaaca gtctatagag agcattggaa gtagcagttt gggtttttgt
     4681 ttaaatttgg ttttcctttc ttgttttttt ttttccactt tgtttttttt tttttgtttt
     4741 gttttgtttt gttttgtttt tttaatgaag ggccctcctt ccaaattcag aaagcataca
     4801 tggtaacagt ttgctattat ccagtcctct ctccacactt agggcctttc caatttgttt
     4861 gtattttttc tttaaaaaaa caaaacacac aggcataagt aaacataacc aaagccacat
     4921 tatttggctg ggggagtggg gaggataaca gtatttatcc catctattga gagattactt
     4981 acatcgaaat aaaacttcgg tcagtacagg taataacgtg caatgttggg gtgttatttg
     5041 ggtcttggcc ttgctgatgg tcagtaggag gagccctgtc tccttccctc tccagctaag
     5101 cagcttctgt aaccagcttg gctcccttct ttgtattttc tactctgcag aggaccgaga
     5161 gtgtttgcag aggggaaaca atgggcagtg tggggcctgt cgactttatt tgctttactc
     5221 taaaagcatg tggaaacaga atgctttcct ctttcctttt ttaagcagcc tcgtctgaac
     5281 tattaccagg cagtgactct gaggcagtac aaacttcatt atgtgcagta aaaagttttc
     5341 tcttgctaga tgtggtagca cacacaagtc cagcactggg aggcaggggc aagagaaggg
     5401 cacgtttgag gccagcccgg gctatagagt agaactttat ctcagaaaga aaggaaagtt
     5461 tctttgttga aagaaaaagc tgaatataat aatttcaagg ttaaaatggg aaatgatcac
     5521 aatatgtaaa gctagggaca gaccactcag tgaccaactg tcttttgtaa acaaggaaaa
     5581 gggaaacatt ttgatggttc tccgtatcta ttctaagccc ttgtctcctg ctttccctta
     5641 ctttttctcc ctcagttatt ctgactaaat tgataatgaa tgtaggtaaa atgttgtccc
     5701 tgccttctta aaaatttaag tagacactta actttactat ggtgcctaac tggtggtttt
     5761 cagcaaacat taactattag agaaaggaaa atattgtgtc tttatagttt ctttctaccc
     5821 tcacccatca cagtcctgta ttcatcctgt tcttgctgtt tcagaggcga ttgggtggta
     5881 tccttacatg atactgcgta ggcgtgtctt agaggcaggg ggtactgaga aagcagcgtc
     5941 ctgaggaatc catgttatcc ctcagcaaat agcatcttgg tgctttcagt acccacctct
     6001 caccctcacc ctcaccctca tttgagttgc ctgagtcatt gctgtggagg ggagagcttt
     6061 cttccctgca ttaaaaactt tgtttgtgtt tctgcatcga atccctaagg ggaagacaat
     6121 cgtggatctt ggaatgtttc tgtctttgta tctgggaagc agacactgca cactaggttt
     6181 tctggtagtg tgttgcaccg gggcacacgc tgaggacctc cagctaggtg tgctgcacca
     6241 gtgtgttgag cttttgaagg aattccagca agttcacaca ggactctaca gaggaaagaa
     6301 aaggagggct ttggattcct cagtggggtg ggtagggaat ggagggaagg gtggcctgtg
     6361 gttgaagaca atccttttgt cttggagcaa accacttttt ttttttcctg aagaaaggct
     6421 gtccagcaga gcccgggagc tgtgatctct gtgaggtaca gcaagaatcc tcagaattca
     6481 catccgtttt gagccagttc tttcctctca agcctttctg ccctataggt ctcctcacaa
     6541 aaatgcatga tatcatgacc tcgtgttttg ggttgggtat aacatagcaa agcaagggaa
     6601 atatagttat atactgagtc ttaagacatt tgtttagtaa aaaagaaaaa aaggtatcaa
     6661 acagagaatg ggggcggggg cggggaaatt gtgactttca gaattgattt ttttttccca
     6721 gaaattaagt gggggtattt ttcagtctag aataaaagaa tgtgaattct ttctaccgct
     6781 cttatttaaa cttaaatata ctgtttactt gaaaaggctc tcttgactat ttgattttct
     6841 aagaaaacag ggaagtatca ggaaagtggt ttctgaaatg ttgaagcagg ataactgtct
     6901 tcaaaagcat agcggccgcc acaagacagg agtgcgttgt acagttcaag gacggacttt
     6961 tcagggcttg gggtttgtgg gatatttttt gttttgtttt gtttttgcca caagatcttc
     7021 agtgtgtttg tttcagggtg gaagtgggtg ttatatgaag ctgtcagata ttttaaggaa
     7081 atcttcctac aacagtaaat gaagacatct gtatatatgt gatatagtga aacaaaagac
     7141 atttctggta ttcataaaga taaaacaagg attttattct tcctgtgtct gtgatttaaa
     7201 ctcggtacca tactctggct tttgtatttc accctaagtt taaaaataaa taaacaagat
     7261 attttttaaa gaatgcacaa catagtgtgt cttagcaagg acatgagtca tatgaagcag
     7321 agtgagtagt tgtcactaag gtccttgatg ctcactgtaa aaacacaaag agttccatga
     7381 atactctagt accacacaga agtaccacag tggtgctgtg tcacatagga ccctgaagga
     7441 ttttctgaga gttgattcag cttagatggg agctccctcc ctgcaactct ctgccttcct
     7501 ggtgtcatca gaacttggtt tgactcctag gaaggtatca tgagcagact aggacctttc
     7561 tcctctctga acccagaaac cttgtttatg agaagtgtgg tacagcaagc tggtctccac
     7621 catgtgagta ggtgcaggtt tcttactgca cagtatccac tcagtcctaa tattacctgc
     7681 tgatggagtt aggcctcagc tgttagtttt tgaagcggct gtaaattact gctcctcccc
     7741 caccaccttc atatttttaa ctggtggggt tacctgttaa aattaaaaaa aaaaaataga
     7801 tatgttggat tgatattctc tcacgtgttg gattgatatt ctctcacgtg ttcagtgtgg
     7861 aaaacaagta catgctttag aggcaacaac agtgaaatcc ttttggaatg tgtattaata
     7921 tcatttaata aaataactag ttctaaaggt ttgacatttt tctttgagat tggggctttg
     7981 accaagggcc cttggctttt ctggtaagtg caaacaaaag tgacttctcc tcccaggagc
     8041 cgaagctgca acgctgcagt acagacctat ggttagagat gctaaattct ctccgttgca
     8101 gatgcagcat ggctacccag ggccaaaggt gaaacaggct acagaatgga gaacgagaat
     8161 ctggggacag ccctgaagat gccactagac tgcctttcca cctgagggta tgtgggaagg
     8221 acaaatggtg gtacgtgtgg gcacgcacac ctgaggcaca tgtgccgcag acccccaccc
     8281 tcacccccac cccgtatgtt ttcttcattg ctgcttgcac ttacctctcc catcgtcttg
     8341 gagaaaaaaa aaaaaacaaa ctgcctccaa tactttgttt tccagcttaa taaaatatgt
     8401 ttttgtttgt tgcgtggtt
//
