LOCUS       NM_145938               2736 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus ribonuclease P 40 subunit (Rpp40), mRNA.
ACCESSION   NM_145938
VERSION     NM_145938.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2736)
  AUTHORS   Durkin ME, Yuan BZ, Thorgeirsson SS and Popescu NC.
  TITLE     Gene structure, tissue expression, and linkage mapping of the mouse
            DLC-1 gene (Arhgap7)
  JOURNAL   Gene 288 (1-2), 119-127 (2002)
   PUBMED   12034501
REFERENCE   2  (bases 1 to 2736)
  AUTHORS   Jarrous N, Eder PS, Guerrier-Takada C, Hoog C and Altman S.
  TITLE     Autoantigenic properties of some protein subunits of catalytically
            active complexes of human ribonuclease P
  JOURNAL   RNA 4 (4), 407-417 (1998)
   PUBMED   9630247
REFERENCE   3  (bases 1 to 2736)
  AUTHORS   Brady KP, Rowe LB, Her H, Stevens TJ, Eppig J, Sussman DJ, Sikela J
            and Beier DR.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK048810.1, AC134860.4 and AC159209.2.
            
            [WARNING] On Dec 12, 2023 this sequence was replaced by
            NM_145938.5.
            
            On Apr 4, 2008 this sequence version replaced NM_145938.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because transcript sequence consistent with
            the reference genome assembly was not available for all regions of
            the RefSeq transcript. The extent of this transcript is supported
            by transcript alignments.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus to one that is more supported by available conservation
            data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK048810.1, BC024607.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-243               AK048810.1         1-243
            244-244             AC134860.4         165293-165293
            245-2408            AK048810.1         245-2408
            2409-2736           AC159209.2         4949-5276
FEATURES             Location/Qualifiers
     source          1..2736
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 14.44 cM"
     gene            1..2736
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /note="ribonuclease P 40 subunit"
                     /db_xref="GeneID:208366"
                     /db_xref="MGI:MGI:1346084"
     exon            1..144
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..1113
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /EC_number="3.1.26.5"
                     /note="RNaseP protein p40; ribonuclease P 40kDa subunit;
                     ribonuclease P1"
                     /codon_start=1
                     /product="ribonuclease P protein subunit p40"
                     /protein_id="NP_666050.3"
                     /db_xref="CCDS:CCDS26451.2"
                     /db_xref="GeneID:208366"
                     /db_xref="MGI:MGI:1346084"
                     /translation="MATLRRLQEAPRHLLVCEKSNFGHDKSRHKHLVETHYHNYRVSF
                     LIPECGLLSKELKSLVMDIGPYYSVKNLPLHELITHEFINTFVKKGSFSALTYNTSID
                     EDNTVALLPNGKLILSLDKDTYEETGLQGRPSRYSGRKSMKFVISIDLMDLSLNLDSK
                     KYRRISWSFKEKKPLKFDFLLAWHPTGTEESTMMSYFSKYQIQEHQPKVALSTVRELQ
                     CPVLRSSGLAGEPEEACSALEFFDWLGAVFCSADLNNEPYNFISTYCCPQPSAVVAQA
                     FLCTITGFILPEKIHVLLEQLCHYFDEPKLAPWVTLTVQGFADSPVAWREKEHGFHKG
                     GEHLYNFVVFNNQDYWLQMAVGANDDCPP"
     exon            145..289
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /inference="alignment:Splign:2.1.0"
     exon            290..358
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /inference="alignment:Splign:2.1.0"
     exon            359..454
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /inference="alignment:Splign:2.1.0"
     exon            455..580
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /inference="alignment:Splign:2.1.0"
     exon            581..779
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /inference="alignment:Splign:2.1.0"
     exon            780..914
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /inference="alignment:Splign:2.1.0"
     exon            915..2736
                     /gene="Rpp40"
                     /gene_synonym="D8Bwg1265e; Rnasep1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcgcctggac tcctgcttaa catggccacg ctgcgcaggc tgcaagaggc gcctcggcac
       61 ttactggtct gtgagaaatc caacttcggc cacgataagt ctcgccataa gcatctcgtg
      121 gagacgcact atcataatta cagggtttca tttcttattc ctgaatgtgg gcttctatca
      181 aaagagctaa aaagcctggt catggacatt ggaccctatt actctgtgaa gaacttacct
      241 cttcatgaat taattacaca cgagttcatc aacacctttg taaagaaagg ttcattctct
      301 gcattaacat acaatacaag tattgatgag gataatactg ttgctctcct accaaatggg
      361 aaattaattt tatcactaga taaagatact tacgaagaaa ccggacttca aggtcgtcca
      421 tctcggtatt ctggcagaaa aagtatgaag tttgtcattt ccattgacct aatggattta
      481 tcccttaacc tggattctaa gaagtacaga agaatatctt ggtccttcaa agagaagaag
      541 cctttgaagt ttgatttcct tttggcttgg catcctacag gtacagaaga atcaacaatg
      601 atgtcgtact tttccaaata ccaaattcag gagcatcagc ccaaagtggc attgagcaca
      661 gtgagagagc tgcagtgccc agtgctgcgg agcagcgggc ttgcaggaga gccggaggag
      721 gcctgcagtg ccctggagtt ctttgactgg cttggtgctg tcttctgcag tgcggaccta
      781 aataacgagc cttataactt catatcaacc tactgctgtc cccagccaag cgccgtggta
      841 gcccaagctt ttctgtgtac aatcacaggt ttcatattgc cagagaagat acatgtcctt
      901 ctggaacagc tgtgtcacta cttcgatgaa ccaaagttgg ctccatgggt caccttgaca
      961 gttcaaggct ttgcagacag ccccgttgcc tggagagaga aggaacatgg cttccataaa
     1021 ggaggcgagc acttgtacaa ttttgtggtt ttcaataatc aggactattg gcttcagatg
     1081 gctgttgggg caaatgatga ctgcccacca taaaagatgc aaagtttata gagtcacacc
     1141 ttgcttgttt gttgtcatgt ttcctcatca caaagtgtta tatgtcaccc agacttgcta
     1201 cagtgattag cttcccagct cagctctggc ttgcttcctc ctgtgccgtg gcccctgtgc
     1261 actggctgct tatcctacga tcagctctga gctggttttt cagttgaatg cagagtgttg
     1321 cttactagag agtagggtaa accggaatga ttgagaatag caggagtgga gcacttggtg
     1381 agtgttctag gtgctaatca tggatgaact cttctagttt ggttttctgt tggccagagc
     1441 aacgtctgtg aggacaggac cgactgcagt ccatcatcag tgatggaacc tagagacagg
     1501 aactgaagca gagaccatgg aggaatgcca ctcggcttgc tcacctagct ttcttatata
     1561 gcccaggacc tgcttaggat taataccgcc cactgttggc tggacccccc ttgatgaacc
     1621 agcattcaag aaaatacccc atagacatgc ttaggagcca gattgatgga ggtggttcct
     1681 caactgaggt ttcttccgcc caagtgtatc agcagataac caagatgaac catcagaatt
     1741 tttgtgtgtc cccaggatct catgttgata taaaatacag tgcaaattga aaagtcacac
     1801 cgtcttttaa gaacaccact acgtaaaaat tcagtgtctc ttaaaagtcc aaacttcctt
     1861 aaccatgact tcctataaaa tcaaggttga ataccttctt acagcaaaag ggaagaacca
     1921 cacttaaaac caaagtccaa aaaggtagct ccagaatcac agggcctgac atctgggact
     1981 cactcaccgt cttctggact ccaaggcaat tctcagcaca cagcatgtct agtaggctaa
     2041 ggctgggtcc ttgctgacgt gacagccatc ttgactctta gagcacacgc tgctcacgtg
     2101 cttatgtgac agtggtgtga acaaaccctc ctttgctgcc agtggtgtga agttcagtaa
     2161 ttagaagtgt gtacagcaca tgacacttaa taacttactg gcttatgagt ttactccttc
     2221 tacttataga aaagtatgaa tcaccgtggg atgatattgg gagcagctat tgatcaccac
     2281 gtcttttaac cacatccatt accttttgca gcttccctta atttcatttt ttgttcatca
     2341 tgatcctgga agcaataagc ttctctctct ctctctctct ctctctctct ctctctctct
     2401 ctctctctct ctgtgtgtgt gtgtgtgtgt gtgtgtgtct gtgtctgtgt ctgtgtctgt
     2461 gtctgtgtct gtgtatcata tatcctagat gtctagaagg caataaacca tctggtttta
     2521 tgcaagtatc tcctgcagtg atcacgtaac aaccaaattg cctgtcaata cttgccttag
     2581 cccatgtccc tgtcatcatg tgacccaata ctatgtatac ctgcccccta ccctgaatct
     2641 tccaaccgtt ctattctttc tccctcaaga atgtaagcac cagcccagca ggaagtcaga
     2701 ggtggttttg gttttggggt gcttctgctc tcatgt
//
