LOCUS       NM_013721                872 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus ribosomal protein L7A (Rpl7a), transcript variant 1,
            mRNA.
ACCESSION   NM_013721
VERSION     NM_013721.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 872)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (bases 1 to 872)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 872)
  AUTHORS   Saez,I., Gerbracht,J.V., Koyuncu,S., Lee,H.J., Horn,M., Kroef,V.,
            Denzel,M.S., Dieterich,C., Gehring,N.H. and Vilchez,D.
  TITLE     The E3 ubiquitin ligase UBR5 interacts with the H/ACA
            ribonucleoprotein complex and regulates ribosomal RNA biogenesis in
            embryonic stem cells
  JOURNAL   FEBS Lett 594 (1), 175-188 (2020)
   PUBMED   31365120
REFERENCE   4  (bases 1 to 872)
  AUTHORS   Jiang,Q., Wu,G., Yang,L., Lu,Y.P., Liu,X.X., Han,F., Deng,Y.P.,
            Fu,X.C., Liu,Q.B. and Lu,Y.M.
  TITLE     Elucidation of the FKBP25-60S Ribosomal Protein L7a Stress Response
            Signaling During Ischemic Injury
  JOURNAL   Cell Physiol Biochem 47 (5), 2018-2030 (2018)
   PUBMED   29969783
  REMARK    GeneRIF: findings reveal that the nuclear import of FKBP25 and
            binding with 60S ribosomal protein L7a are protective stress
            responses to ischemia/nitrosaive stress injury.
REFERENCE   5  (bases 1 to 872)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   6  (bases 1 to 872)
  AUTHORS   Feo,S., Davies,B. and Fried,M.
  TITLE     The mapping of seven intron-containing ribosomal protein genes
            shows they are unlinked in the human genome
  JOURNAL   Genomics 13 (1), 201-207 (1992)
   PUBMED   1577483
REFERENCE   7  (bases 1 to 872)
  AUTHORS   Taylor,K.D. and Piko,L.
  TITLE     Expression of ribosomal protein genes in mouse oocytes and early
            embryos
  JOURNAL   Mol Reprod Dev 31 (3), 182-188 (1992)
   PUBMED   1554502
REFERENCE   8  (bases 1 to 872)
  AUTHORS   Haas,I.G., Simon-Chazottes,D. and Guenet,J.L.
  TITLE     The gene coding for the immunoglobulin heavy chain binding protein
            BiP (Hsce-70) maps to mouse chromosome 2
  JOURNAL   Mamm Genome 3 (11), 659-660 (1992)
   PUBMED   1450517
REFERENCE   9  (bases 1 to 872)
  AUTHORS   Stubbs,L., Huxley,C., Hogan,B., Evans,T., Fried,M., Duboule,D. and
            Lehrach,H.
  TITLE     The HOX-5 and surfeit gene clusters are linked in the proximal
            portion of mouse chromosome 2
  JOURNAL   Genomics 6 (4), 645-650 (1990)
   PUBMED   1971250
REFERENCE   10 (bases 1 to 872)
  AUTHORS   Huxley,C. and Fried,M.
  TITLE     The mouse surfeit locus contains a cluster of six genes associated
            with four CpG-rich islands in 32 kilobases of genomic DNA
  JOURNAL   Mol Cell Biol 10 (2), 605-614 (1990)
   PUBMED   2300057
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL773563.12.
            
            On Mar 21, 2023 this sequence version replaced NM_013721.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160621.1, BC099389.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AL773563.12        114337-114361
            26-146              AL773563.12        114537-114657
            147-296             AL773563.12        114953-115102
            297-437             AL773563.12        115550-115690
            438-517             AL773563.12        115897-115976
            518-648             AL773563.12        116202-116332
            649-718             AL773563.12        116519-116588
            719-872             AL773563.12        116696-116849
FEATURES             Location/Qualifiers
     source          1..872
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 19.1 cM"
     gene            1..872
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /note="ribosomal protein L7A"
                     /db_xref="GeneID:27176"
                     /db_xref="MGI:MGI:1353472"
     exon            1..25
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..823
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /note="surfeit 3; 60S ribosomal protein L7a; surfeit locus
                     protein 3"
                     /codon_start=1
                     /product="large ribosomal subunit protein eL8"
                     /protein_id="NP_038749.1"
                     /db_xref="CCDS:CCDS15815.1"
                     /db_xref="GeneID:27176"
                     /db_xref="MGI:MGI:1353472"
                     /translation="MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQD
                     IQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKY
                     RPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHD
                     VDPIELVVFLPALCRKMGVPYCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKL
                     VEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG"
     exon            26..146
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /inference="alignment:Splign:2.1.0"
     exon            147..296
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /inference="alignment:Splign:2.1.0"
     exon            297..437
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /inference="alignment:Splign:2.1.0"
     exon            438..517
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /inference="alignment:Splign:2.1.0"
     exon            518..648
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /inference="alignment:Splign:2.1.0"
     exon            649..718
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /inference="alignment:Splign:2.1.0"
     exon            719..872
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      849..854
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /note="hexamer: AATATA"
     polyA_site      872
                     /gene="Rpl7a"
                     /gene_synonym="Surf3"
                     /note="major polyA site"
ORIGIN      
        1 ctttctccag cagccgagca agatgcccaa agggaagaag gccaagggga agaaggtggc
       61 cccggccccc gccgtcgtca agaagcagga ggccaagaag gtggtcaacc ctctgttcga
      121 gaagaggccc aagaacttcg gcattggaca ggacatccag cccaaaagag atttaacgcg
      181 cttcgtcaaa tggccccgct acatcagact gcagcggcaa agagctatcc tctacaagcg
      241 gctcaaagtc cctcctgcca ttaaccagtt cacccaggcc ctggacaggc agacagctac
      301 tcagctgctt aagcttgccc acaagtacag gccagagaca aagcaagaga agaagcaaag
      361 gctactggcc cgtgctgaga agaaagctgc tggcaaaggc gacgtcccaa ctaagagacc
      421 acctgtcctc cgagcaggag tcaatacagt caccaccttg gtggagaaca agaaggctca
      481 gctggtggtg attgcccatg acgtagaccc cattgagctg gtggttttcc tacctgctct
      541 gtgtcgaaag atgggggtgc cctactgcat catcaaggga aaggccaggc tggggcacct
      601 ggtccacagg aagacatgca ccaccgttgc cttcacacag gttaactcgg aagacaaggg
      661 tgctctggct aagctggtgg aagctattag gaccaattat aatgacagat atgacgagat
      721 ccgtcgccac tggggaggca acgtcctggg tcctaagtct gtggctcgaa ttgccaagct
      781 ggaaaaagca aaggctaaag aactcgccac taaattgggt taaatgtaca ctaaattttc
      841 tgtacctaaa tataattaca aaattatctt ga
//
