LOCUS       NM_011291                937 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus ribosomal protein L7 (Rpl7), mRNA.
ACCESSION   NM_011291
VERSION     NM_011291.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Borisova,E., Newman,A.G., Couce Iglesias,M., Dannenberg,R.,
            Schaub,T., Qin,B., Rusanova,A., Brockmann,M., Koch,J., Daniels,M.,
            Turko,P., Jahn,O., Kaplan,D.R., Rosario,M., Iwawaki,T.,
            Spahn,C.M.T., Rosenmund,C., Meierhofer,D., Kraushar,M.L.,
            Tarabykin,V. and Ambrozkiewicz,M.C.
  TITLE     Protein translation rate determines neocortical neuron fate
  JOURNAL   Nat Commun 15 (1), 4879 (2024)
   PUBMED   38849354
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 937)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   3  (bases 1 to 937)
  AUTHORS   Kraushar,M.L., Viljetic,B., Wijeratne,H.R., Thompson,K., Jiao,X.,
            Pike,J.W., Medvedeva,V., Groszer,M., Kiledjian,M., Hart,R.P. and
            Rasin,M.R.
  TITLE     Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical
            Ribosome Signature and mRNA Translation to Specify Neocortical Cell
            Subtypes
  JOURNAL   J Neurosci 35 (31), 10911-10926 (2015)
   PUBMED   26245956
REFERENCE   4  (bases 1 to 937)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   5  (bases 1 to 937)
  AUTHORS   Kraushar,M.L., Thompson,K., Wijeratne,H.R., Viljetic,B., Sakers,K.,
            Marson,J.W., Kontoyiannis,D.L., Buyske,S., Hart,R.P. and Rasin,M.R.
  TITLE     Temporally defined neocortical translation and polysome assembly
            are determined by the RNA-binding protein Hu antigen R
  JOURNAL   Proc Natl Acad Sci U S A 111 (36), E3815-E3824 (2014)
   PUBMED   25157170
REFERENCE   6  (bases 1 to 937)
  AUTHORS   Cramer,S.D., Barnard,R., Engbers,C., Ogren,L. and Talamantes,F.
  TITLE     Expression of the growth hormone receptor and growth
            hormone-binding protein during pregnancy in the mouse
  JOURNAL   Endocrinology 131 (2), 876-882 (1992)
   PUBMED   1639029
REFERENCE   7  (bases 1 to 937)
  AUTHORS   Taylor,K.D. and Piko,L.
  TITLE     Expression of ribosomal protein genes in mouse oocytes and early
            embryos
  JOURNAL   Mol Reprod Dev 31 (3), 182-188 (1992)
   PUBMED   1554502
REFERENCE   8  (bases 1 to 937)
  AUTHORS   Haas,I.G., Simon-Chazottes,D. and Guenet,J.L.
  TITLE     The gene coding for the immunoglobulin heavy chain binding protein
            BiP (Hsce-70) maps to mouse chromosome 2
  JOURNAL   Mamm Genome 3 (11), 659-660 (1992)
   PUBMED   1450517
REFERENCE   9  (bases 1 to 937)
  AUTHORS   Meyuhas,O. and Klein,A.
  TITLE     The mouse ribosomal protein L7 gene. Its primary structure and
            functional analysis of the promoter region
  JOURNAL   J Biol Chem 265 (20), 11465-11473 (1990)
   PUBMED   2365680
REFERENCE   10 (bases 1 to 937)
  AUTHORS   Williams,T., Yon,J., Huxley,C. and Fried,M.
  TITLE     The mouse surfeit locus contains a very tight cluster of four
            'housekeeping' genes that is conserved through evolution
  JOURNAL   Proc Natl Acad Sci U S A 85 (10), 3527-3530 (1988)
   PUBMED   2453062
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB839528.1, AK050656.1 and BY441493.1.
            
            On Aug 1, 2009 this sequence version replaced NM_011291.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC025909.1, DV072123.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                BB839528.1         1-37
            38-931              AK050656.1         13-906
            932-937             BY441493.1         381-386
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 4.94 cM"
     gene            1..937
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /note="ribosomal protein L7"
                     /db_xref="GeneID:19989"
                     /db_xref="MGI:MGI:98073"
     exon            1..69
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..868
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /note="60S ribosomal protein L7"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL30"
                     /protein_id="NP_035421.2"
                     /db_xref="CCDS:CCDS14829.1"
                     /db_xref="GeneID:19989"
                     /db_xref="MGI:MGI:98073"
                     /translation="MEAVPEKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKR
                     RNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGN
                     FYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEP
                     YIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLIARSLGKFGIICMEDLIHEIYT
                     VGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN"
     exon            70..244
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /inference="alignment:Splign:2.1.0"
     exon            245..411
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /inference="alignment:Splign:2.1.0"
     exon            412..549
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /inference="alignment:Splign:2.1.0"
     exon            550..659
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /inference="alignment:Splign:2.1.0"
     exon            660..869
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /inference="alignment:Splign:2.1.0"
     exon            870..934
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      905..910
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /note="hexamer: AATAAA"
     polyA_site      934
                     /gene="Rpl7"
                     /gene_synonym="Rpl7a; Surf-3"
                     /note="major polyA site"
ORIGIN      
        1 tttaaggaga cagtgcgcat gcgccacctt tctctcttct tttccggctg gaaccatgga
       61 ggctgttcca gagaagaaaa agaaggttgc cactgtgcca ggaaccctta agaaaaaggt
      121 tcctgctggg ccaaaaactc tcaagaaaaa ggttcccgct gtgccagaaa ccctcaagaa
      181 aaagcgaagg aatttcgcag agttgaaggt gaagcgcctg aggaagaagt ttgccctgaa
      241 gacacttcga aaggcaagga ggaagctcat ctatgagaag gcaaagcact atcacaagga
      301 gtacaggcag atgtaccgca ctgagattcg gatggccagg atggcaagga aagctggcaa
      361 cttctatgtg cccgcagaac caaagctggc ctttgtcatc agaattcgag gtatcaatgg
      421 agtaagccca aaggttcgta aggttctgca gctccttcgt cttcgacaga tcttcaatgg
      481 cacctttgtt aagctcaaca aggcttcaat taacatgctg cggattgtgg agccatacat
      541 tgcatggggg taccccaacc tgaagtcagt aaacgagctc atctacaagc gaggctacgg
      601 caaaatcaac aagaagcgga ttgccttgac agataattcc ttgattgctc ggtctcttgg
      661 taagtttggc atcatctgca tggaggatct aattcatgag atctatacag tcgggaaacg
      721 cttcaaggaa gcaaataact tcctgtggcc cttcaagtta tcttccccac gaggtgggat
      781 gaagaaaaag acaactcact ttgtagaagg tggagatgct ggcaacaggg aagaccagat
      841 aaacaggctt attagacgga tgaactaagg tgtcacccat tgtatttttg taatctggtc
      901 agttaataaa cagtcacagc ttggcaaatt gaaaaaa
//
