LOCUS       NM_011290               1282 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus ribosomal protein L6 (Rpl6), transcript variant 1,
            mRNA.
ACCESSION   NM_011290
VERSION     NM_011290.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1282)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (bases 1 to 1282)
  AUTHORS   Chern,T., Achilleos,A., Tong,X., Hill,M.C., Saltzman,A.B.,
            Reineke,L.C., Chaudhury,A., Dasgupta,S.K., Redhead,Y., Watkins,D.,
            Neilson,J.R., Thiagarajan,P., Green,J.B.A., Malovannaya,A.,
            Martin,J.F., Rosenblatt,D.S. and Poche,R.A.
  TITLE     Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin
            metabolism and ribosomopathy
  JOURNAL   Nat Commun 13 (1), 134 (2022)
   PUBMED   35013307
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1282)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   4  (bases 1 to 1282)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
REFERENCE   5  (bases 1 to 1282)
  AUTHORS   Collins,M.O., Husi,H., Yu,L., Brandon,J.M., Anderson,C.N.,
            Blackstock,W.P., Choudhary,J.S. and Grant,S.G.
  TITLE     Molecular characterization and comparison of the components and
            multiprotein complexes in the postsynaptic proteome
  JOURNAL   J Neurochem 97 Suppl 1, 16-23 (2006)
   PUBMED   16635246
REFERENCE   6  (bases 1 to 1282)
  AUTHORS   Pfisterer,P., Ehlermann,J., Hegen,M. and Schorle,H.
  TITLE     A subtractive gene expression screen suggests a role of
            transcription factor AP-2 alpha in control of proliferation and
            differentiation
  JOURNAL   J Biol Chem 277 (8), 6637-6644 (2002)
   PUBMED   11741941
REFERENCE   7  (bases 1 to 1282)
  AUTHORS   Jakel,S., Mingot,J.M., Schwarzmaier,P., Hartmann,E. and Gorlich,D.
  TITLE     Importins fulfil a dual function as nuclear import receptors and
            cytoplasmic chaperones for exposed basic domains
  JOURNAL   EMBO J 21 (3), 377-386 (2002)
   PUBMED   11823430
REFERENCE   8  (bases 1 to 1282)
  AUTHORS   Thomson,S.R. and Johnson,S.E.
  TITLE     Isolation and characterization of chicken TaxREB107, a putative DNA
            binding protein abundantly expressed in muscle
  JOURNAL   Gene 278 (1-2), 81-88 (2001)
   PUBMED   11707324
REFERENCE   9  (bases 1 to 1282)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
REFERENCE   10 (bases 1 to 1282)
  AUTHORS   Nacken,W., Klempt,M. and Sorg,C.
  TITLE     The mouse homologue of the HTLV-I tax responsive element binding
            protein TAXREB107 is a highly conserved gene which may regulate
            some basal cellular functions
  JOURNAL   Biochim Biophys Acta 1261 (3), 432-434 (1995)
   PUBMED   7537974
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK153208.1, AK151022.1 and CJ316043.1.
            
            On Jul 31, 2009 this sequence version replaced NM_011290.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK150540.1, AK151344.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                AK153208.1         2-31
            31-1239             AK151022.1         3-1211
            1240-1282           CJ316043.1         279-321
FEATURES             Location/Qualifiers
     source          1..1282
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 61.72 cM"
     gene            1..1282
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /note="ribosomal protein L6"
                     /db_xref="GeneID:19988"
                     /db_xref="MGI:MGI:108057"
     exon            1..52
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..943
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /note="60S ribosomal protein L6; TAX-responsive enhancer
                     element-binding protein 107"
                     /codon_start=1
                     /product="large ribosomal subunit protein eL6"
                     /protein_id="NP_035420.2"
                     /db_xref="CCDS:CCDS19632.1"
                     /db_xref="GeneID:19988"
                     /db_xref="MGI:MGI:108057"
                     /translation="MAGEKAPDTKEKKPAAKKAGSDAAASRPRAAKVAKKVHPKGKKP
                     KKAKPHCSRNPVLVRGIGRYSRSAMYSRKALYKRKYSAAKTKVEKKKKKEKVLATVTK
                     TVGGDKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRRLRSSITPGTVLII
                     LTGRHRGKRVVFLKQLDSGLLLVTGPLVINRVPLRRTHQKFVIATSTKVDISDVKIPK
                     HLTDAYFKKKQLRKPRHQEGEIFDTEKEKYEITEQRKADQKAVDLQILPKIKAVPQLQ
                     GYLRSQFSLTNGMYPHKLVF"
     exon            53..310
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /inference="alignment:Splign:2.1.0"
     exon            311..412
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /inference="alignment:Splign:2.1.0"
     exon            413..556
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /inference="alignment:Splign:2.1.0"
     exon            557..605
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /inference="alignment:Splign:2.1.0"
     exon            606..790
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /inference="alignment:Splign:2.1.0"
     exon            791..1250
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /inference="alignment:Splign:2.1.0"
     regulatory      956..961
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /note="hexamer: ATTAAA"
     polyA_site      976
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /note="major polyA site"
     regulatory      1223..1228
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
                     /note="hexamer: AATAGA"
     polyA_site      1250
                     /gene="Rpl6"
                     /gene_synonym="Taxreb107"
ORIGIN      
        1 attgcttata gaccggaagc cgctgcctta gttctctttc ccgtcttgca agatggcggg
       61 tgaaaaagcg cctgatacaa aggagaagaa acctgcggcc aagaaggctg gcagtgatgc
      121 tgctgcctcc cggccccggg ccgccaaagt agccaaaaag gttcacccta agggtaaaaa
      181 gcccaagaag gcgaagcccc attgcagccg aaaccctgtc ctggtgagag gaattggcag
      241 gtactcccga tctgctatgt actccaggaa ggccttgtac aaaaggaaat actcggctgc
      301 caagaccaag gttgagaaga agaagaaaaa agagaaggtc cttgctactg tcaccaaaac
      361 agttggtggg gacaagaacg gtggcacccg ggtggtgaag cttcgaaaaa tgcctaggta
      421 ttatcccacc gaagatgttc ctcggaagct gctgagccac ggcaagaagc ccttcagcca
      481 gcacgtgaga aggctacgct ccagcatcac tcccggaact gtcctgatca tcctcactgg
      541 gcgccacagg ggcaagagag tggttttcct gaagcagctg gacagtggct tgctgcttgt
      601 gactgggcct cttgtcatca acagagttcc tctgcgcaga acacaccaga agtttgtcat
      661 tgccacctct acaaaagttg atatcagcga tgttaaaatc cccaaacacc tgactgacgc
      721 ttacttcaag aagaagcagc tgcgcaagcc caggcatcag gagggcgaga tcttcgacac
      781 agagaaggag aaatacgaga ttacagagca gcgaaaggct gaccagaaag ctgtggattt
      841 gcagattttg ccaaagatta aagctgttcc tcagctccag ggctacctgc gctctcagtt
      901 ttccctgaca aacgggatgt atcctcacaa actggtcttc taaattgtta acctaattaa
      961 acagcttcat aggttctttt ggtgtccttt ttgtgtgttg tgtgtgcaca tgtttgttgg
     1021 gtgggtgttt tgctggtgtc ttttcctctg tgtcttcctc tggccctttc tggaaagacc
     1081 tgcttaatct gaagcatgtg agctaggcta gtccactggg tcctgctctc tgcccatccc
     1141 cagctggctt tggattagag gcacatacac tgccatggct gccttttact gtggctgtgg
     1201 ttttgccctt tttttttaag caaatagaaa atgctgctga ctatactgga aaaaaaaaaa
     1261 aaaaaaaaaa aaaaaaaaaa aa
//
