LOCUS       NM_001163945            1369 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus ribosomal protein L3-like (Rpl3l), transcript variant
            1, mRNA.
ACCESSION   NM_001163945
VERSION     NM_001163945.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1369)
  AUTHORS   Bajpai,A.K., Gu,Q., Orgil,B.O., Alberson,N.R., Towbin,J.A.,
            Martinez,H.R., Lu,L. and Purevjav,E.
  TITLE     Exploring the Regulation and Function of Rpl3l in the Development
            of Early-Onset Dilated Cardiomyopathy and Congestive Heart Failure
            Using Systems Genetics Approach
  JOURNAL   Genes (Basel) 15 (1), 53 (2023)
   PUBMED   38254943
  REMARK    GeneRIF: Exploring the Regulation and Function of Rpl3l in the
            Development of Early-Onset Dilated Cardiomyopathy and Congestive
            Heart Failure Using Systems Genetics Approach.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1369)
  AUTHORS   Milenkovic,I., Santos Vieira,H.G., Lucas,M.C., Ruiz-Orera,J.,
            Patone,G., Kesteven,S., Wu,J., Feneley,M., Espadas,G., Sabido,E.,
            Hubner,N., van Heesch,S., Volkers,M. and Novoa,E.M.
  TITLE     Dynamic interplay between RPL3- and RPL3L-containing ribosomes
            modulates mitochondrial activity in the mammalian heart
  JOURNAL   Nucleic Acids Res 51 (11), 5301-5324 (2023)
   PUBMED   36882085
  REMARK    GeneRIF: Dynamic interplay between RPL3- and RPL3L-containing
            ribosomes modulates mitochondrial activity in the mammalian heart.
REFERENCE   3  (bases 1 to 1369)
  AUTHORS   Shiraishi,C., Matsumoto,A., Ichihara,K., Yamamoto,T., Yokoyama,T.,
            Mizoo,T., Hatano,A., Matsumoto,M., Tanaka,Y., Matsuura-Suzuki,E.,
            Iwasaki,S., Matsushima,S., Tsutsui,H. and Nakayama,K.I.
  TITLE     RPL3L-containing ribosomes determine translation elongation
            dynamics required for cardiac function
  JOURNAL   Nat Commun 14 (1), 2131 (2023)
   PUBMED   37080962
  REMARK    GeneRIF: RPL3L-containing ribosomes determine translation
            elongation dynamics required for cardiac function.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1369)
  AUTHORS   Grimes,K.M., Prasad,V., Huo,J., Kuwabara,Y., Vanhoutte,D.,
            Baldwin,T.A., Bowers,S.L.K., Johansen,A.K.Z., Sargent,M.A.,
            Lin,S.J. and Molkentin,J.D.
  TITLE     Rpl3l gene deletion in mice reduces heart weight over time
  JOURNAL   Front Physiol 14, 1054169 (2023)
   PUBMED   36733907
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1369)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   6  (bases 1 to 1369)
  AUTHORS   Kao,B.R., Malerba,A., Lu-Nguyen,N.B., Harish,P., McCarthy,J.J.,
            Dickson,G. and Popplewell,L.J.
  TITLE     Knockdown of Muscle-Specific Ribosomal Protein L3-Like Enhances
            Muscle Function in Healthy and Dystrophic Mice
  JOURNAL   Nucleic Acid Ther 31 (6), 457-464 (2021)
   PUBMED   34081545
  REMARK    GeneRIF: Knockdown of Muscle-Specific Ribosomal Protein L3-Like
            Enhances Muscle Function in Healthy and Dystrophic Mice.
REFERENCE   7  (bases 1 to 1369)
  AUTHORS   Chaillou,T., Zhang,X. and McCarthy,J.J.
  TITLE     Expression of Muscle-Specific Ribosomal Protein L3-Like Impairs
            Myotube Growth
  JOURNAL   J Cell Physiol 231 (9), 1894-1902 (2016)
   PUBMED   26684695
REFERENCE   8  (bases 1 to 1369)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154566.2.
            
            On Dec 6, 2019 this sequence version replaced NM_001163945.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and it encodes the longer protein (isoform 1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189679.78295.1,
                                           SRR5189670.38158.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                AC154566.2         35235-35295         c
            62-254              AC154566.2         34612-34804         c
            255-423             AC154566.2         32084-32252         c
            424-559             AC154566.2         30650-30785         c
            560-746             AC154566.2         29626-29812         c
            747-907             AC154566.2         29377-29537         c
            908-1009            AC154566.2         29103-29204         c
            1010-1105           AC154566.2         27609-27704         c
            1106-1225           AC154566.2         27280-27399         c
            1226-1369           AC154566.2         26978-27121         c
FEATURES             Location/Qualifiers
     source          1..1369
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.52 cM"
     gene            1..1369
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /note="ribosomal protein L3-like"
                     /db_xref="GeneID:66211"
                     /db_xref="MGI:MGI:1913461"
     exon            1..61
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            62..254
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            255..423
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            424..559
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            560..746
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            747..907
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1009
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1105
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1225
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1369
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1347..1352
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1369
                     /gene="Rpl3l"
                     /gene_synonym="1110057H16Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtcatttgac ctctggtgcc tggtggggag gccccttcct aacctgcagg gatcggccat
       61 gtcccaccgg aagttctctg cccctcggca tggacacctg ggcttcctgc cccacaagag
      121 gagccggcgg caccggggca aggtgaagag ctggcctcgg gatgacccca gccagccggt
      181 gcacctaaca gccttcctgg gctacaaggc tggcatgacc cacacccttc gcgaagtgca
      241 ccgacccgga ctcaaaattt ctaagcgaga ggaggtagaa gctgtgacaa ttgtggagac
      301 gccaccgctg gtggtggtgg gtgtggtggg ctacgtagcc actccgagag gcctgcggag
      361 cttcaagacc atctttgcgg aacacctcag cgatgagtgc cgccggcgat tctacaagga
      421 ctggcacaag agtaagaaga aagcctttac caaagcctgc aagaggtggc gagacgctga
      481 cggcaagaag cagctgcaga aagactttgc tgccatgaag aagtactgca aggtcattcg
      541 ggtcattgtc cacacccaga tgaagttgct gccctttcgg cagaagaagg cccacatcat
      601 ggagattcag ctgaatggtg gcaccgtggc tgagaaggtg gcttgggttc aggcacggat
      661 ggagaagcag gtgcctgtac acagcgtgtt cagccagagt gaggttattg atgtcattgc
      721 tgtcacgaag ggccggggtg ttaaaggggt gaccagtcgc tggcatacca agaagcttcc
      781 aaggaagacc cacaaaggct tgcgcaaagt ggcctgcatc ggcgcctggc accctgcccg
      841 agtaggctgc tccatcgccc gggctgggca gaagggttac caccaccgta cagagctgaa
      901 caagaagatc taccgcattg gccgggggct gcacatggaa gatggaaaga tggtcagaaa
      961 caacgcatcc accagctacg acgtaactga caagtcaatc acacccctgg gtggcttccc
     1021 ccactatggg gaagtgaaca atgacttcat catgttaaag ggctgcattg caggtaccaa
     1081 gaagcgagtg atcactctga gaaagtccct tctggtgcac cacagccgca gggccctgga
     1141 gaatattgag ctcaagttca ttgacaccac ttctaagttt ggccacggat gttttcagac
     1201 agcgcaggag aagagggcct tcatgggtcc ccaaaagaaa catctggaga aagagaagcc
     1261 ggagaccttg ggaaacatgt aagatgtctg gaatggagca cacctgggat gtagcactct
     1321 tgctatctgt ccggtccttt ttgttcaata aagtcctgag gcaactctc
//
