LOCUS       NM_011975               1551 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus ribosomal protein L27A (Rpl27a), mRNA.
ACCESSION   NM_011975
VERSION     NM_011975.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1551)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (bases 1 to 1551)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   3  (bases 1 to 1551)
  AUTHORS   Distler,U., Schmeisser,M.J., Pelosi,A., Reim,D., Kuharev,J.,
            Weiczner,R., Baumgart,J., Boeckers,T.M., Nitsch,R., Vogt,J. and
            Tenzer,S.
  TITLE     In-depth protein profiling of the postsynaptic density from mouse
            hippocampus using data-independent acquisition proteomics
  JOURNAL   Proteomics 14 (21-22), 2607-2613 (2014)
   PUBMED   25211037
REFERENCE   4  (bases 1 to 1551)
  AUTHORS   Terzian,T., Dumble,M., Arbab,F., Thaller,C., Donehower,L.A.,
            Lozano,G., Justice,M.J., Roop,D.R. and Box,N.F.
  TITLE     Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53
            mouse models
  JOURNAL   J Pathol 224 (4), 540-552 (2011)
   PUBMED   21674502
REFERENCE   5  (bases 1 to 1551)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
REFERENCE   6  (bases 1 to 1551)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   7  (bases 1 to 1551)
  AUTHORS   Kusuda,J., Hirai,M., Tanuma,R., Hirata,M. and Hashimoto,K.
  TITLE     Genomic structure and chromosome location of RPL27A/Rpl27a, the
            genes encoding human and mouse ribosomal protein L27A
  JOURNAL   Cytogenet Cell Genet 85 (3-4), 248-251 (1999)
   PUBMED   10449908
REFERENCE   8  (bases 1 to 1551)
  AUTHORS   Takenaka,M., Imai,E., Kaneko,T., Ito,T., Moriyama,T., Yamauchi,A.,
            Hori,M., Kawamoto,S. and Okubo,K.
  TITLE     Isolation of genes identified in mouse renal proximal tubule by
            comparing different gene expression profiles
  JOURNAL   Kidney Int 53 (3), 562-572 (1998)
   PUBMED   9507200
REFERENCE   9  (bases 1 to 1551)
  AUTHORS   Fleming,G., Belhumeur,P., Skup,D. and Fried,H.M.
  TITLE     Functional substitution of mouse ribosomal protein L27' for yeast
            ribosomal protein L29 in yeast ribosomes
  JOURNAL   Proc Natl Acad Sci U S A 86 (1), 217-221 (1989)
   PUBMED   2643099
REFERENCE   10 (bases 1 to 1551)
  AUTHORS   Belhumeur,P., Paterno,G.D., Boileau,G., Claverie,J.M. and Skup,D.
  TITLE     Isolation and characterisation of a murine cDNA clone highly
            homologous to the yeast L29 ribosomal protein gene
  JOURNAL   Nucleic Acids Res 15 (3), 1019-1029 (1987)
   PUBMED   2434927
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124457.4.
            
            On Dec 15, 2022 this sequence version replaced NM_011975.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK010286.1, SRR13422597.387414.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-76                AC124457.4         125731-125806
            77-140              AC124457.4         126169-126232
            141-216             AC124457.4         126502-126577
            217-391             AC124457.4         127052-127226
            392-1551            AC124457.4         128185-129344
FEATURES             Location/Qualifiers
     source          1..1551
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 57.26 cM"
     gene            1..1551
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /note="ribosomal protein L27A"
                     /db_xref="GeneID:26451"
                     /db_xref="MGI:MGI:1347076"
     exon            1..76
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..520
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /EC_number="3.6.5.3"
                     /note="60S ribosomal protein L27a; ribosomal protein L29
                     homolog"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL15"
                     /protein_id="NP_036105.2"
                     /db_xref="CCDS:CCDS40083.1"
                     /db_xref="GeneID:26451"
                     /db_xref="MGI:MGI:1347076"
                     /translation="MPSRLRKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGMHHHRIN
                     FDKYHPGYFGKVGMRHYHLKRNQSFCPTVNLDKLWTLVSEQTRVNAAKNKTGVAPIID
                     VVRSGYYKVLGKGKLPKQPVIVKAKFFSRRAEEKIKGVGGACVLVA"
     exon            77..140
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /inference="alignment:Splign:2.1.0"
     exon            141..216
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /inference="alignment:Splign:2.1.0"
     exon            217..391
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /inference="alignment:Splign:2.1.0"
     exon            392..1551
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /inference="alignment:Splign:2.1.0"
     regulatory      539..544
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /note="hexamer: ATTAAA"
     polyA_site      563
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /note="major polyA site"
     regulatory      1134..1139
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /note="hexamer: AATAAA"
     polyA_site      1160
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
     polyA_site      1478
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
     regulatory      1531..1536
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
                     /note="hexamer: ATTATA"
     polyA_site      1551
                     /gene="Rpl27a"
                     /gene_synonym="L27'; L27A; L29"
ORIGIN      
        1 attggtcccg cccccgcgcc tgctacctcg cgagacttcg tgagctcctc ccttttccct
       61 ttctgccacc gccatgccat ccagactgag gaagacccgg aaactccggg gccacgtgag
      121 ccacggccac ggccgcatcg gtaagcaccg caagcaccca ggcggccgcg ggaatgctgg
      181 aggcatgcac caccacagga tcaactttga caaatatcac ccaggttact ttgggaaagt
      241 tggtatgcgg cattaccact tgaagaggaa ccagagcttc tgcccaacag tcaacctgga
      301 taaactgtgg acattggtca gcgagcagac acgggtcaat gcggcaaaaa acaagactgg
      361 agttgctccc atcattgatg ttgttcgatc aggctactac aaagttctgg gcaagggaaa
      421 gctccctaag caacctgtca tcgtgaaggc caaattcttc agcagaagag ctgaggagaa
      481 gattaagggt gttggaggtg cctgtgttct ggtggcttaa aagccacacc ggaggttaat
      541 taaatgctaa cattttccat gtggtctttg catccttcct tgtctgcatg ttggaaatct
      601 gcctaacatt ctaggaagag gtgaggtgtg ggcccttgag agtcagtctg tgggaataag
      661 tgtagcccaa ctatgcacag ttgtaaattc ctacatcccc gtgtgtattg gtcttgatat
      721 tcaaagaatt gatgaatgcc attactttca gtccaaagtg aagaaacctg gtctcaaaaa
      781 atcccgagga ccagaaatga gatgggtttt cctgaaaatc taaagttctt gaaaaacctt
      841 gccatccaga ttgctagcaa ctgcctagct ttgtaagctt actgtgatgg acaggtagct
      901 caggacgact ggtcacttaa tactggacag attagcatgg aaaacttaag gggaggagga
      961 ggtagtaggt tccatccagc ttcgctttgt tggtggcatc taggtgttgt tccaagggag
     1021 catgcctacc tgcaacagga catcactggt tgggaatact gtagaaccag agctgtgacc
     1081 tttgaactac tagaaagatg aaattttatg taaagagtac cttggagtaa ataaataaag
     1141 cccaagatcc tgattgtcta catctttaaa tctggaagtt tttagggagt aggttgtgta
     1201 tgcttagtac tgacgctgct ttagtagaca agtgcgtagt aagaggcagt ataagttggg
     1261 tcactaaata cggaaaaatt cattttaaga tgtgttgggg gacaaaagac ttctggctct
     1321 agagataata ctgtgtgctg cccctagtcc agatgatgta tctgtttatg ggtggaggat
     1381 gattgacatg catgtggcag tcgggacaat tatagggtcc gtaacatgac aattgtgtat
     1441 gtaaccacag taattctatg taaaggttta ggcatgtggc tgcattgtta tttcctaaag
     1501 catatattta caggtttttt ttataacact attatactaa gatgtaagtt a
//
