LOCUS       NP_035419                136 aa            linear   ROD 27-APR-2025
DEFINITION  large ribosomal subunit protein eL27 [Mus musculus].
ACCESSION   NP_035419
VERSION     NP_035419.1
DBSOURCE    REFSEQ: accession NM_011289.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 136)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (residues 1 to 136)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   3  (residues 1 to 136)
  AUTHORS   Distler,U., Schmeisser,M.J., Pelosi,A., Reim,D., Kuharev,J.,
            Weiczner,R., Baumgart,J., Boeckers,T.M., Nitsch,R., Vogt,J. and
            Tenzer,S.
  TITLE     In-depth protein profiling of the postsynaptic density from mouse
            hippocampus using data-independent acquisition proteomics
  JOURNAL   Proteomics 14 (21-22), 2607-2613 (2014)
   PUBMED   25211037
REFERENCE   4  (residues 1 to 136)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
REFERENCE   5  (residues 1 to 136)
  AUTHORS   Sehic,A., Risnes,S., Khan,Q.E., Khuu,C. and Osmundsen,H.
  TITLE     Gene expression and dental enamel structure in developing mouse
            incisor
  JOURNAL   Eur J Oral Sci 118 (2), 118-130 (2010)
   PUBMED   20487000
REFERENCE   6  (residues 1 to 136)
  AUTHORS   Larsen,H.S., Ruus,A.K., Schreurs,O. and Galtung,H.K.
  TITLE     Aquaporin 11 in the developing mouse submandibular gland
  JOURNAL   Eur J Oral Sci 118 (1), 9-13 (2010)
   PUBMED   20156259
REFERENCE   7  (residues 1 to 136)
  AUTHORS   Sehic,A., Khuu,C., Risnes,S. and Osmundsen,H.
  TITLE     Differential gene expression profiling of the molar tooth germ in
            peroxisome proliferator-activated receptor-alpha (PPAR-alpha)
            knockout mouse and in wild-type mouse: molar tooth phenotype of
            PPAR-alpha knockout mouse
  JOURNAL   Eur J Oral Sci 117 (2), 93-104 (2009)
   PUBMED   19320717
REFERENCE   8  (residues 1 to 136)
  AUTHORS   Maggi,L.B. Jr., Kuchenruether,M., Dadey,D.Y., Schwope,R.M.,
            Grisendi,S., Townsend,R.R., Pandolfi,P.P. and Weber,J.D.
  TITLE     Nucleophosmin serves as a rate-limiting nuclear export chaperone
            for the Mammalian ribosome
  JOURNAL   Mol Cell Biol 28 (23), 7050-7065 (2008)
   PUBMED   18809582
REFERENCE   9  (residues 1 to 136)
  AUTHORS   Osmundsen,H., Landin,M.A., From,S.H., Kolltveit,K.M. and Risnes,S.
  TITLE     Changes in gene-expression during development of the murine molar
            tooth germ
  JOURNAL   Arch Oral Biol 52 (9), 803-813 (2007)
   PUBMED   17374359
REFERENCE   10 (residues 1 to 136)
  AUTHORS   Belhumeur,P., Paterno,G.D., Boileau,G., Claverie,J.M. and Skup,D.
  TITLE     Isolation and characterisation of a murine cDNA clone highly
            homologous to the yeast L29 ribosomal protein gene
  JOURNAL   Nucleic Acids Res 15 (3), 1019-1029 (1987)
   PUBMED   2434927
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN831363.1, AK132027.1 and BQ748836.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ748836.1, CN831363.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..136
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 65.05 cM"
     Protein         1..136
                     /product="large ribosomal subunit protein eL27"
                     /EC_number="3.6.5.3"
                     /note="60S ribosomal protein L27"
                     /calculated_mol_wt=15667
     Region          1..136
                     /region_name="KOW"
                     /note="an acronym for the authors' surnames (Kyrpides,
                     Ouzounis and Woese); cl00354"
                     /db_xref="CDD:469738"
     Site            order(7..15,18,22..29,42..47,52..54,56,59..61,67)
                     /site_type="other"
                     /note="RNA binding site [nucleotide binding]"
                     /db_xref="CDD:240514"
     Site            27
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:23576753; propagated from
                     UniProtKB/Swiss-Prot (P61358.2)"
     Site            93
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:P61353; propagated from
                     UniProtKB/Swiss-Prot (P61358.2)"
     CDS             1..136
                     /gene="Rpl27"
                     /coded_by="NM_011289.3:215..625"
                     /db_xref="CCDS:CCDS25470.1"
                     /db_xref="GeneID:19942"
                     /db_xref="MGI:MGI:98036"
ORIGIN      
        1 mgkfmkpgkv vlvlagrysg rkavivknid dgtsdrpysh alvagidryp rkvtaamgkk
       61 kiakrskiks fvkvynynhl mptrysvdip ldktvvnkdv frdpalkrka rreakvkfee
      121 ryktgknkwf fqklrf
//
