LOCUS       NM_029751               1291 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ribosomal protein L18A (Rpl18a), mRNA.
ACCESSION   NM_029751 XM_001001472 XM_001001483 XM_903236
VERSION     NM_029751.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1291)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (bases 1 to 1291)
  AUTHORS   Tiu,G.C., Kerr,C.H., Forester,C.M., Krishnarao,P.S.,
            Rosenblatt,H.D., Raj,N., Lantz,T.C., Zhulyn,O., Bowen,M.E.,
            Shokat,L., Attardi,L.D., Ruggero,D. and Barna,M.
  TITLE     A p53-dependent translational program directs tissue-selective
            phenotypes in a model of ribosomopathies
  JOURNAL   Dev Cell 56 (14), 2089-2102 (2021)
   PUBMED   34242585
REFERENCE   3  (bases 1 to 1291)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   4  (bases 1 to 1291)
  AUTHORS   Distler,U., Schmeisser,M.J., Pelosi,A., Reim,D., Kuharev,J.,
            Weiczner,R., Baumgart,J., Boeckers,T.M., Nitsch,R., Vogt,J. and
            Tenzer,S.
  TITLE     In-depth protein profiling of the postsynaptic density from mouse
            hippocampus using data-independent acquisition proteomics
  JOURNAL   Proteomics 14 (21-22), 2607-2613 (2014)
   PUBMED   25211037
REFERENCE   5  (bases 1 to 1291)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ042325.1 and AK161942.1.
            
            On Dec 7, 2007 this sequence version replaced NM_029751.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK161942.1, CA326122.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                CJ042325.1         2-32
            32-1291             AK161942.1         2-1261
FEATURES             Location/Qualifiers
     source          1..1291
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.38 cM"
     gene            1..1291
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /note="ribosomal protein L18A"
                     /db_xref="GeneID:76808"
                     /db_xref="MGI:MGI:1924058"
     exon            1..85
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..598
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /note="60S ribosomal protein L18a"
                     /codon_start=1
                     /product="large ribosomal subunit protein eL20"
                     /protein_id="NP_084027.1"
                     /db_xref="CCDS:CCDS22386.1"
                     /db_xref="GeneID:76808"
                     /db_xref="MGI:MGI:1924058"
                     /translation="MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRF
                     WYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTT
                     AGAVTQCYRDMGARHRARAHSIQIMKVEEIAAGKCRRPAVKQFHDSKIKFPLPHRVLR
                     RQHKPRFTTKRPNTFF"
     exon            86..265
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            266..395
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            396..505
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            506..1291
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      615..620
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      634
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
                     /note="major polyA site"
     polyA_site      714
                     /gene="Rpl18a"
                     /gene_synonym="2510019J09Rik"
ORIGIN      
        1 atggtgagag cctgcgcgaa agacaacact tccttttgtg actggcggtg aacgagtgcg
       61 cagtgccatg aaggcctcgg gcacgcttcg ggagtacaag gtggtggggc gctgcttgcc
      121 aaccccaaaa tgccacacac caccactgta ccgtatgcga atctttgcac ccaaccatgt
      181 ggtggccaag tcccgcttct ggtactttgt gtcacagctg aagaagatga agaagtcatc
      241 cggggaaatt gtgtactgcg gacaggtgtt tgagaagtca cccctgcgtg tgaagaactt
      301 tggcatctgg ctgcgctatg actcccgcag tggcacacac aacatgtatc gggagtacag
      361 ggacctgacc actgctggtg cagtcacaca gtgctaccga gacatgggtg cccgacaccg
      421 tgcccgtgcc cactccatcc agatcatgaa ggtggaagag attgcagctg gcaagtgccg
      481 ccggccagct gtcaagcagt tccacgactc caagatcaaa ttcccactgc cccaccgtgt
      541 gttgcggcgc cagcacaagc cacgcttcac caccaagagg cccaacacct tcttctagac
      601 acagagaccc actgaataaa aacttgagac tgtccttgct tgtttgcttc tatgtccctg
      661 gagaggtccc agttggtccc gtccctaaca acatgctagc cctgctcacc tgcctgtcag
      721 ccttgctcag tggcatcttt ccataggtgt gtatcccctt agattagctt cagccccact
      781 acgatttgtc taggacatag cctgagccct gcctgtgaca ctgaggggta gcagtctgtt
      841 tctggactcc agggtgctgc tgtctcaggc ctaagaattc cagacatgac tataatccaa
      901 gcctggggac ctggttgagc tttttatcct gctggctcta agcttcagct aggtggaaat
      961 gaggccagcc aagccccaca gtgagcttgc aagctttaga tggggacagg gttacgcttt
     1021 ggtgaatgat ggaggaaaca tgggggttcc ttttgttggg tgcagccagc acggcatcat
     1081 catggtgccc aatcttgaaa gggcacaggc ctgaagcttc ctgggactgt tctgtcacag
     1141 ggaggaacct actgcagttg cctacaattg ctacctctga gggacttgcc tctggcccct
     1201 tgtagacatt tccatgtcta cacatggccc agagtacttt cagggatagc aatgtgtgaa
     1261 tggcacttag aagataacat gtgaaagcca t
//
