LOCUS       NM_009077                646 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus ribosomal protein L18 (Rpl18), transcript variant 1,
            mRNA.
ACCESSION   NM_009077 XM_976842
VERSION     NM_009077.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 646)
  AUTHORS   Szakats,S., McAtamney,A., Cross,H. and Wilson,M.J.
  TITLE     Sex-biased gene and microRNA expression in the developing mouse
            brain is associated with neurodevelopmental functions and
            neurological phenotypes
  JOURNAL   Biol Sex Differ 14 (1), 57 (2023)
   PUBMED   37679839
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 646)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   3  (bases 1 to 646)
  AUTHORS   Nakagawa,T., Hattori,S., Nobuta,R., Kimura,R., Nakagawa,M.,
            Matsumoto,M., Nagasawa,Y., Funayama,R., Miyakawa,T., Inada,T.,
            Osumi,N., Nakayama,K.I. and Nakayama,K.
  TITLE     The Autism-Related Protein SETD5 Controls Neural Cell Proliferation
            through Epigenetic Regulation of rDNA Expression
  JOURNAL   iScience 23 (4), 101030 (2020)
   PUBMED   32299058
REFERENCE   4  (bases 1 to 646)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   5  (bases 1 to 646)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
REFERENCE   6  (bases 1 to 646)
  AUTHORS   Taylor,K.D. and Piko,L.
  TITLE     Expression of ribosomal protein genes in mouse oocytes and early
            embryos
  JOURNAL   Mol Reprod Dev 31 (3), 182-188 (1992)
   PUBMED   1554502
REFERENCE   7  (bases 1 to 646)
  AUTHORS   Agrawal,M.G. and Bowman,L.H.
  TITLE     Transcriptional and translational regulation of ribosomal protein
            formation during mouse myoblast differentiation
  JOURNAL   J Biol Chem 262 (10), 4868-4875 (1987)
   PUBMED   3558374
REFERENCE   8  (bases 1 to 646)
  AUTHORS   Peled-Yalif,E., Cohen-Binder,I. and Meyuhas,O.
  TITLE     Isolation and characterization of four mouse ribosomal-protein-L18
            genes that appear to be processed pseudogenes
  JOURNAL   Gene 29 (1-2), 157-166 (1984)
   PUBMED   6149171
REFERENCE   9  (bases 1 to 646)
  AUTHORS   D'Eustachio,P., Meyuhas,O., Ruddle,F. and Perry,R.P.
  TITLE     Chromosomal distribution of ribosomal protein genes in the mouse
  JOURNAL   Cell 24 (2), 307-312 (1981)
   PUBMED   7237550
REFERENCE   10 (bases 1 to 646)
  AUTHORS   Meyuhas,O. and Perry,R.P.
  TITLE     Construction and identification of cDNA clones for mouse ribosomal
            proteins: application for the study of r-protein gene expression
  JOURNAL   Gene 10 (2), 113-129 (1980)
   PUBMED   6993285
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC167242.4.
            
            On Feb 28, 2023 this sequence version replaced NM_009077.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB195604.1, CA319991.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AC167242.4         118760-118799
            41-127              AC167242.4         119913-119999
            128-235             AC167242.4         120189-120296
            236-334             AC167242.4         120580-120678
            335-528             AC167242.4         120954-121147
            529-646             AC167242.4         121374-121491
FEATURES             Location/Qualifiers
     source          1..646
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.45 cM"
     gene            1..646
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /note="ribosomal protein L18"
                     /db_xref="GeneID:19899"
                     /db_xref="MGI:MGI:98003"
     exon            1..40
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..604
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /note="isoform 1 is encoded by transcript variant 1; 60S
                     ribosomal protein L18; large ribosomal subunit protein
                     eL18"
                     /codon_start=1
                     /product="large ribosomal subunit protein eL18 isoform 1"
                     /protein_id="NP_033103.2"
                     /db_xref="CCDS:CCDS39958.1"
                     /db_xref="GeneID:19899"
                     /db_xref="MGI:MGI:98003"
                     /translation="MGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFN
                     QVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRILEVPKLKVCA
                     LRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPH
                     SHTKPYVRSKGRKFERARGRRASRGYKN"
     exon            41..127
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /inference="alignment:Splign:2.1.0"
     exon            128..235
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /inference="alignment:Splign:2.1.0"
     exon            236..334
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /inference="alignment:Splign:2.1.0"
     exon            335..528
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /inference="alignment:Splign:2.1.0"
     exon            529..646
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      623..628
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /note="hexamer: AATAAA"
     polyA_site      646
                     /gene="Rpl18"
                     /gene_synonym="L18; Rpl18a"
                     /note="major polyA site"
ORIGIN      
        1 ccgtctttcc ggacctggcc gagcaggagg cgccatcatg ggtgttgaca ttcgccacaa
       61 caaggaccga aaggttcggc gcaaggagcc caagagccag gacatctacc tgcggctgct
      121 tgtcaagctg tacaggtttc tggccagacg gaccaactcc accttcaatc aggttgtgct
      181 gaagaggttg ttcatgagcc gaaccaaccg gccacctctg tccctgtccc gcatgatccg
      241 aaagatgaag cttcctggcc gcgagaacaa gactgccgtg gttgtgggga cggtcacaga
      301 tgatgtgcgg attctggaag ttcccaagct gaaggtgtgt gcactgcggg tgagcagccg
      361 ggcccggagt cgcatcctca aggctggggg taagatcctc acctttgacc agctggccct
      421 ggagtctccc aagggccggg gcactgtgct cctgtctggt cctcggaagg gccgagaggt
      481 gtaccgacat tttggcaagg ccccaggaac cccacacagc cataccaaac cctatgtccg
      541 ttccaagggc cggaagtttg agcgcgccag aggccgaagg gccagcagag gctacaaaaa
      601 ctaaccctgg atcttaactg ttaataaaaa aaacattgga tgatga
//
