LOCUS       NM_025586               1857 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ribosomal protein L15 (Rpl15), transcript variant 3,
            mRNA.
ACCESSION   NM_025586
VERSION     NM_025586.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   2  (bases 1 to 1857)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   3  (bases 1 to 1857)
  AUTHORS   Distler,U., Schmeisser,M.J., Pelosi,A., Reim,D., Kuharev,J.,
            Weiczner,R., Baumgart,J., Boeckers,T.M., Nitsch,R., Vogt,J. and
            Tenzer,S.
  TITLE     In-depth protein profiling of the postsynaptic density from mouse
            hippocampus using data-independent acquisition proteomics
  JOURNAL   Proteomics 14 (21-22), 2607-2613 (2014)
   PUBMED   25211037
REFERENCE   4  (bases 1 to 1857)
  AUTHORS   Plaks,V., Gershon,E., Zeisel,A., Jacob-Hirsch,J., Neeman,M.,
            Winterhager,E., Rechavi,G., Domany,E. and Dekel,N.
  TITLE     Blastocyst implantation failure relates to impaired translational
            machinery gene expression
  JOURNAL   Reproduction 148 (1), 87-98 (2014)
   PUBMED   24700326
REFERENCE   5  (bases 1 to 1857)
  AUTHORS   Kondrashov,N., Pusic,A., Stumpf,C.R., Shimizu,K., Hsieh,A.C.,
            Ishijima,J., Shiroishi,T. and Barna,M.
  TITLE     Ribosome-mediated specificity in Hox mRNA translation and
            vertebrate tissue patterning
  JOURNAL   Cell 145 (3), 383-397 (2011)
   PUBMED   21529712
REFERENCE   6  (bases 1 to 1857)
  AUTHORS   Wang,H., Zhao,L.N., Li,K.Z., Ling,R., Li,X.J. and Wang,L.
  TITLE     Overexpression of ribosomal protein L15 is associated with cell
            proliferation in gastric cancer
  JOURNAL   BMC Cancer 6, 91 (2006)
   PUBMED   16608517
  REMARK    GeneRIF: RPL15 promotes cell proliferation in gastric neoplasms
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1857)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   8  (bases 1 to 1857)
  AUTHORS   Zhang,J., Gao,F.L., Zhi,H.Y., Luo,A.P., Ding,F., Wu,M. and Liu,Z.H.
  TITLE     Expression patterns of esophageal cancer deregulated genes in
            C57BL/6J mouse embryogenesis
  JOURNAL   World J Gastroenterol 10 (8), 1088-1092 (2004)
   PUBMED   15069704
REFERENCE   9  (bases 1 to 1857)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC087917.1, AK168807.1 and AW491775.1.
            
            On Mar 10, 2007 this sequence version replaced NM_025586.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BG807085.1, AK168807.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-703               BC087917.1         28-730
            704-1838            AK168807.1         696-1830
            1839-1857           AW491775.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 7.08 cM"
     gene            1..1857
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /note="ribosomal protein L15"
                     /db_xref="GeneID:66480"
                     /db_xref="MGI:MGI:1913730"
     exon            1..28
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            29..210
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..653
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /note="60S ribosomal protein L15"
                     /codon_start=1
                     /product="large ribosomal subunit protein eL15"
                     /protein_id="NP_079862.1"
                     /db_xref="CCDS:CCDS36812.1"
                     /db_xref="GeneID:66480"
                     /db_xref="MGI:MGI:1913730"
                     /translation="MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTR
                     PDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVA
                     EERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHRE
                     MRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR"
     exon            211..347
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            348..1841
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      683..688
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      705
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /note="major polyA site"
     regulatory      1819..1824
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1841
                     /gene="Rpl15"
                     /gene_synonym="2510008H07Rik"
ORIGIN      
        1 cttcctttcc tctggcggca gccatcaggt gagccaagat gggtgcatac aagtacatcc
       61 aggagctatg gaggaagaag cagtccgacg tgatgcgctt tcttctgagg gtccgctgtt
      121 ggcaataccg ccagctctct gcgctgcaca gggctccccg ccccacccgg cctgataaag
      181 ctcgaagact gggatacaag gctaagcaag gctatgtcat ttacaggatt cgtgtccgcc
      241 gtggtggtcg taaacgccca gttcctaagg gtgcaactta cggcaagcct gtccaccatg
      301 gtgttaacca gctgaaattt gcccgaagcc ttcagtctgt tgctgaggag agagctgggc
      361 gccattgtgg ggctttgaga gtcctgaatt cctactgggt tggtgaagat tccacatata
      421 aattttttga ggttatcctc attgatccgt tccataaagc tatcagaaga aatcctgaca
      481 cccagtggat caccaaacca gtccacaaac acagagaaat gcgtgggctg acatctgctg
      541 gccgaaagag ccgtggcctt ggaaagggcc acaagttcca ccacactatt ggtggttccc
      601 gccgtgcagc ctggagaagg cgcaatactc tccagctcca ccgttaccgc taatacacgt
      661 gatatttgta aaattcatat ccaataaaca atttaggaca gtcatttctg cttaaaggtg
      721 ttatttgtta aaactagtct acagattgtc atgagtgttc tgtgaaaatg tagaagttaa
      781 gtgcaataat tgaaaactgc aggtgatggc atatcttgtt tctgatgtac tttgcattat
      841 ctgcttatga gattaagtgt atatagtgtt tgtgccaagt ggtgttctgt gtgtaagacc
      901 ctgtaagagg taaaaagtcc tgaaactgac cctggatgtg ttggtgcatg agatagaatc
      961 tacagcttta cgatggcatc ttttggttca ctgaagtggc tgcttgggag tttgatgagt
     1021 acaaacttta tagagttgga ttttgcttag aaatgtgtag gaagagaggg tttcaaaacc
     1081 tgttttgtgc atagaaaagt gagatcaact ataacccaca ttttgagaat tgaatccagt
     1141 gttattttca gaagaccagg taaatttgtt ggaagaggtt tcactttctg ttggatctag
     1201 agtatggatt tggagatgaa ggttgaacat tggatgtagt agggcttatt tagggcagat
     1261 tatttccatt agatttgtaa acttggttgt ggttgcaagt taatatcaac caagcaaata
     1321 taagtttgat taagcttgca gacattaagc ttttctagca gctggtgtgt gcagaggcag
     1381 atggctctct ggttccagga ctacctacaa tatagagaaa ttttctctat tccagtcaat
     1441 tcatcatggg taagaatagt ccattttggt agtgttattt catcgtttac aatctaccta
     1501 tgggtagtgg ctggtaactg cctggatgtt gacatttcac aaaggccata cttaaccaca
     1561 cttttatttc tatttgtgcg atgccttgga gtagtttccc aaagtgattt tgagtgtgga
     1621 agaaatggta ttgtccccga acagctggct tggtctcaaa atctaattga tgcttttatt
     1681 aaattggttt tcctttggag attttaaaag gatgatttga tttccagaaa atactagact
     1741 caaaatcttg atagctaaaa ttcttttcta ttcagcaaaa caagtcactg tatagaggtt
     1801 gttcaaatca actaaagtaa taaatgtctt aaacaagtgg aaaaaaaaaa aaaaaaa
//
